Hippocampal study unveils distinct protein machineries for calcium channel clustering and vesicle priming

by Ingrid Fadelli , Medical XpressMunc13-1 and CaV2.1 nanoclustering. a–c, Example STED images of sideview synapses (a), quantification of line profiles (b) and Pearson's colocalization coefficien

Updated on: September 23,2024

Hippocampal study unveils distinct protein machineries for calcium channel clustering and vesicle priming

by Ingrid Fadelli , Medical XpressMunc13-1 and CaV2.1 nanoclustering. a–c, Example STED images of sideview synapses (a), quantification of line profiles (b) and Pearson's colocalization coefficien

Updated on:September 23,2024

Traumatic memories can rewire the brain: Study

by National Institutes of Natural SciencesDetecting learning-dependent changes in neural networks to understand how memory is made in the prefrontal region of the brain. Credit: Masakazu Agetsuma

Updated on: February 05,2024

Traumatic memories can rewire the brain: Study

by National Institutes of Natural SciencesDetecting learning-dependent changes in neural networks to understand how memory is made in the prefrontal region of the brain. Credit: Masakazu Agetsuma

Updated on:February 05,2024

Clinical trial suggests ALS drug effective for treating spinal cord injuries

by Laurie Fickman,University of HoustonRiluzole trough and peak concentrations from Phase I and Phase II/III trials presented in waterfall plots. Credit:Journal of Neurotrauma(2023).

Updated on: January 11,2024

Clinical trial suggests ALS drug effective for treating spinal cord injuries

by Laurie Fickman,University of HoustonRiluzole trough and peak concentrations from Phase I and Phase II/III trials presented in waterfall plots. Credit:Journal of Neurotrauma(2023).

Updated on:January 11,2024

Researchers uncover shared cellular mechanisms across three major dementias

byUniversity of California, Los AngelesCredit: Pixabay/CC0 Public DomainResearchers have for the first time identified degeneration-associated "molecular markers"—observable changes in

Updated on: September 15,2024

Researchers uncover shared cellular mechanisms across three major dementias

byUniversity of California, Los AngelesCredit: Pixabay/CC0 Public DomainResearchers have for the first time identified degeneration-associated "molecular markers"—observable changes in

Updated on:September 15,2024

Alzheimer's research with primates could address treatments that show promise in mice but don't help humans

by Agnès Lacreuse, Allyson J. Bennett and Amanda M. Dettmer,The ConversationRhesus macaques experience an aging process similar to people’s. Credit: Unsplash/CC0 Public DomainAs of 2022, an esti

Updated on: May 26,2024

Alzheimer's research with primates could address treatments that show promise in mice but don't help humans

by Agnès Lacreuse, Allyson J. Bennett and Amanda M. Dettmer,The ConversationRhesus macaques experience an aging process similar to people’s. Credit: Unsplash/CC0 Public DomainAs of 2022, an esti

Updated on:May 26,2024

Overlooked brain organ plays key role in promoting brain repair after stroke, researchers discover

byUniversity of CincinnatiFluorescent image of a healthy choroid plexus, the main producer of cerebrospinal fluid in the brain. Credit: Agnes (Yu) LuoUniversity of Cincinnati researchers have pi

Updated on: July 08,2024

Overlooked brain organ plays key role in promoting brain repair after stroke, researchers discover

byUniversity of CincinnatiFluorescent image of a healthy choroid plexus, the main producer of cerebrospinal fluid in the brain. Credit: Agnes (Yu) LuoUniversity of Cincinnati researchers have pi

Updated on:July 08,2024

Presence hallucinations: An early predictor of cognitive decline in Parkinson's disease

by Ecole Polytechnique Federale de LausanneEarly hallucinations in Parkinson's disease are associated with frontal cognitive decline (triangles), and preceded by specific frontal neural oscil

Updated on: February 18,2024

Presence hallucinations: An early predictor of cognitive decline in Parkinson's disease

by Ecole Polytechnique Federale de LausanneEarly hallucinations in Parkinson's disease are associated with frontal cognitive decline (triangles), and preceded by specific frontal neural oscil

Updated on:February 18,2024

Synthetic peptide can inhibit toxicity, aggregation of protein in Alzheimer's disease

by University of WashingtonPET scan of a human brain with Alzheimer's disease. Credit: public domainAlzheimer's is a disease of aggregation. Neurons in the human brain make a protein call

Updated on: June 07,2024

Synthetic peptide can inhibit toxicity, aggregation of protein in Alzheimer's disease

by University of WashingtonPET scan of a human brain with Alzheimer's disease. Credit: public domainAlzheimer's is a disease of aggregation. Neurons in the human brain make a protein call

Updated on:June 07,2024

Scientists identify mutated gene behind mirror movement disorder

byUniversity of MontrealArhgef7 is required for Netrin-1–mediated commissural axon guidance. (A) The mean mRNA expression, fragments per kilobase of transcript per million mapped reads (fpkm), (

Updated on: April 22,2024

Scientists identify mutated gene behind mirror movement disorder

byUniversity of MontrealArhgef7 is required for Netrin-1–mediated commissural axon guidance. (A) The mean mRNA expression, fragments per kilobase of transcript per million mapped reads (fpkm), (

Updated on:April 22,2024

Alzheimer's diagnosis, management improved by brain scans

by Alzheimer's AssociationAmyloid-positive (left) and amyloid-negative (right) PET scans can respectively be used to diagnose or rule out Alzheimer's disease in individuals with memory loss or

Updated on: April 25,2024

Alzheimer's diagnosis, management improved by brain scans

by Alzheimer's AssociationAmyloid-positive (left) and amyloid-negative (right) PET scans can respectively be used to diagnose or rule out Alzheimer's disease in individuals with memory loss or

Updated on:April 25,2024

Good news, bad news from Alzheimer's vaccine trial

by Marianne Madeiros and Robin FosterAn experimental Alzheimer's vaccine appears to safely clear abnormal tau protein from the brain, but it's not yet clear whether the shot will be able to sa

Updated on: April 16,2024

Good news, bad news from Alzheimer's vaccine trial

by Marianne Madeiros and Robin FosterAn experimental Alzheimer's vaccine appears to safely clear abnormal tau protein from the brain, but it's not yet clear whether the shot will be able to sa

Updated on:April 16,2024

Combining amino acid PET and MRI imaging: Aggressive brain tumors could soon be treated more effectively

by Politechnika Bydgoska im Jana i Jedrzeja SniadeckichA new procedure for performing a PET scan using tyrosine will allow for more precise localization of brain tumors. Credit: Franciszek Lukaszczyk

Updated on: January 12,2024

Combining amino acid PET and MRI imaging: Aggressive brain tumors could soon be treated more effectively

by Politechnika Bydgoska im Jana i Jedrzeja SniadeckichA new procedure for performing a PET scan using tyrosine will allow for more precise localization of brain tumors. Credit: Franciszek Lukaszczyk

Updated on:January 12,2024