APOE4 triggers early breakdowns in the blood-brain barrier

by University of Southern CaliforniaCredit: CC0 Public DomainNew USC research reveals how APOE4, a genetic culprit for Alzheimer's disease, triggers leaks in the brain's plumbing system,

Updated on: March 26,2024

APOE4 triggers early breakdowns in the blood-brain barrier

by University of Southern CaliforniaCredit: CC0 Public DomainNew USC research reveals how APOE4, a genetic culprit for Alzheimer's disease, triggers leaks in the brain's plumbing system,

Updated on:March 26,2024

Synthetic peptide can inhibit toxicity, aggregation of protein in Alzheimer's disease

by University of WashingtonPET scan of a human brain with Alzheimer's disease. Credit: public domainAlzheimer's is a disease of aggregation. Neurons in the human brain make a protein call

Updated on: June 07,2024

Synthetic peptide can inhibit toxicity, aggregation of protein in Alzheimer's disease

by University of WashingtonPET scan of a human brain with Alzheimer's disease. Credit: public domainAlzheimer's is a disease of aggregation. Neurons in the human brain make a protein call

Updated on:June 07,2024

Unlocking the mystery of tau for treatment of neurodegenerative diseases

by Nagoya UniversityUnder normal physiological conditions, FUS and SFPQ interact in the nucleus of nerve cells and regulate the alternative splicing of MAPT by excising exon 10. When this functio

Updated on: July 01,2024

Unlocking the mystery of tau for treatment of neurodegenerative diseases

by Nagoya UniversityUnder normal physiological conditions, FUS and SFPQ interact in the nucleus of nerve cells and regulate the alternative splicing of MAPT by excising exon 10. When this functio

Updated on:July 01,2024

Traumatic memories can rewire the brain: Study

by National Institutes of Natural SciencesDetecting learning-dependent changes in neural networks to understand how memory is made in the prefrontal region of the brain. Credit: Masakazu Agetsuma

Updated on: February 05,2024

Traumatic memories can rewire the brain: Study

by National Institutes of Natural SciencesDetecting learning-dependent changes in neural networks to understand how memory is made in the prefrontal region of the brain. Credit: Masakazu Agetsuma

Updated on:February 05,2024

Is Alzheimer's caused by disruptions to the brain's energy supply?

by Kira Shaw And Orla Bonnar,The ConversationCredit: AI-generated imageIt is well known that Alzheimer's disease, the most common form of dementia, involves the accumulation of sticky protei

Updated on: April 20,2024

Is Alzheimer's caused by disruptions to the brain's energy supply?

by Kira Shaw And Orla Bonnar,The ConversationCredit: AI-generated imageIt is well known that Alzheimer's disease, the most common form of dementia, involves the accumulation of sticky protei

Updated on:April 20,2024

Researchers identify neurons responsible for key activity transition in brain development

byKing's College LondonCredit:Neuron(2024). DOI: 10.1016/j.neuron.2024.03.014Scientists at the Center for Developmental Neurobiology and MRC Center for Neurodevelopmental Disorde

Updated on: April 28,2024

Researchers identify neurons responsible for key activity transition in brain development

byKing's College LondonCredit:Neuron(2024). DOI: 10.1016/j.neuron.2024.03.014Scientists at the Center for Developmental Neurobiology and MRC Center for Neurodevelopmental Disorde

Updated on:April 28,2024

Early diagnosis of Alzheimer's: Ultra-long protein fibrils give clues on dementia risk

by Swiss Federal Laboratories for Materials Science and TechnologyAtomic force microscopy: Peter Nirmalraj investigates Alzheimer's disease at the nanometer scale. Credit: EmpaThe early detec

Updated on: April 18,2024

Early diagnosis of Alzheimer's: Ultra-long protein fibrils give clues on dementia risk

by Swiss Federal Laboratories for Materials Science and TechnologyAtomic force microscopy: Peter Nirmalraj investigates Alzheimer's disease at the nanometer scale. Credit: EmpaThe early detec

Updated on:April 18,2024

Living with Alzheimer's: China's health time bomb

Credit: CC0 Public DomainThe first time Chen Shaohua went missing and was picked up by police, the 68-year-old's family put it down to confusion.When he disappeared a second time, they realised he

Updated on: April 25,2024

Living with Alzheimer's: China's health time bomb

Credit: CC0 Public DomainThe first time Chen Shaohua went missing and was picked up by police, the 68-year-old's family put it down to confusion.When he disappeared a second time, they realised he

Updated on:April 25,2024

Alzheimer's disease could be treated with gene therapy, animal study suggests

by Imperial College LondonBrain cells from a mouse cortex that didn't receive the gene therapy. The amyloid plaques are shown in green, and the glial cells, which surround the plaques, are sh

Updated on: May 22,2024

Alzheimer's disease could be treated with gene therapy, animal study suggests

by Imperial College LondonBrain cells from a mouse cortex that didn't receive the gene therapy. The amyloid plaques are shown in green, and the glial cells, which surround the plaques, are sh

Updated on:May 22,2024

ALS and frontotemporal dementia show origins in utero, according to new study

by Cristy Lytal,Keck School of Medicine of USCGrpahical abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112983Even though neurodegenerative diseases often strike in m

Updated on: June 05,2024

ALS and frontotemporal dementia show origins in utero, according to new study

by Cristy Lytal,Keck School of Medicine of USCGrpahical abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112983Even though neurodegenerative diseases often strike in m

Updated on:June 05,2024

Identifying typical patterns in the progression towards Alzheimer's disease

by University of MontrealHow the brain progresses from mild cognitive impairment (MCI) to Alzheimer's-type dementia has been an enigma for the scientific community. However, a recent study by

Updated on: February 26,2024

Identifying typical patterns in the progression towards Alzheimer's disease

by University of MontrealHow the brain progresses from mild cognitive impairment (MCI) to Alzheimer's-type dementia has been an enigma for the scientific community. However, a recent study by

Updated on:February 26,2024

Silencing a faulty gene may uncover clues to rare forms of ALS

by National Institutes of HealthCredit: Pixabay/CC0 Public DomainUsing an experimental drug, researchers have been able to suppress a mutated amyotrophic lateral sclerosis (ALS) gene. Studies in

Updated on: February 05,2024

Silencing a faulty gene may uncover clues to rare forms of ALS

by National Institutes of HealthCredit: Pixabay/CC0 Public DomainUsing an experimental drug, researchers have been able to suppress a mutated amyotrophic lateral sclerosis (ALS) gene. Studies in

Updated on:February 05,2024