Cell-type-specific genetic risk contributes to distinct stages of Alzheimer's disease progression, finds study

by Brigham and Women's HospitalCell-type-specific Alzheimer’s disease polygenic risk scores (ADPRS).aA schematic of cell-type-specific PRS derivation.bAn UpSetR plot o

Updated on: February 24,2024

Cell-type-specific genetic risk contributes to distinct stages of Alzheimer's disease progression, finds study

by Brigham and Women's HospitalCell-type-specific Alzheimer’s disease polygenic risk scores (ADPRS).aA schematic of cell-type-specific PRS derivation.bAn UpSetR plot o

Updated on:February 24,2024

Tips to protect long-term brain health

by Tufts UniversityCredit: AI-generated imageThere is a growing understanding of the role lifestyle choices play in preventing and slowing the progression of cognitive decline. While we await new

Updated on: March 02,2024

Tips to protect long-term brain health

by Tufts UniversityCredit: AI-generated imageThere is a growing understanding of the role lifestyle choices play in preventing and slowing the progression of cognitive decline. While we await new

Updated on:March 02,2024

Tool to measure brain blood flow identifies tell-tale signs of dementia and Alzheimer's early

by COSTCredit: COSTA network of over 200 scientists, clinicians and industry partners developed a cost-effective diagnostic tool for measuring the tell-tale signs of dementia and Alzheimer's. The

Updated on: May 05,2024

Tool to measure brain blood flow identifies tell-tale signs of dementia and Alzheimer's early

by COSTCredit: COSTA network of over 200 scientists, clinicians and industry partners developed a cost-effective diagnostic tool for measuring the tell-tale signs of dementia and Alzheimer's. The

Updated on:May 05,2024

Study finds brain waves can be manipulated during REM sleep

byUniversity of SurreyGraphical Abstract. Credit:SLEEP(2024). DOI: 10.1093/sleep/zsae193Brain waves can be manipulated while in rapid eye movement (REM) sleep, a sleep stage associat

Updated on: September 23,2024

Study finds brain waves can be manipulated during REM sleep

byUniversity of SurreyGraphical Abstract. Credit:SLEEP(2024). DOI: 10.1093/sleep/zsae193Brain waves can be manipulated while in rapid eye movement (REM) sleep, a sleep stage associat

Updated on:September 23,2024

Concussions in young children: Symptoms still present three months later

byUniversity of MontrealCredit: Pixabay/CC0 Public DomainConcussions in children aged 6 and under continue to affect their health three months after the event. This is the finding of a study led

Updated on: March 28,2024

Concussions in young children: Symptoms still present three months later

byUniversity of MontrealCredit: Pixabay/CC0 Public DomainConcussions in children aged 6 and under continue to affect their health three months after the event. This is the finding of a study led

Updated on:March 28,2024

Overlooked brain organ plays key role in promoting brain repair after stroke, researchers discover

byUniversity of CincinnatiFluorescent image of a healthy choroid plexus, the main producer of cerebrospinal fluid in the brain. Credit: Agnes (Yu) LuoUniversity of Cincinnati researchers have pi

Updated on: July 08,2024

Overlooked brain organ plays key role in promoting brain repair after stroke, researchers discover

byUniversity of CincinnatiFluorescent image of a healthy choroid plexus, the main producer of cerebrospinal fluid in the brain. Credit: Agnes (Yu) LuoUniversity of Cincinnati researchers have pi

Updated on:July 08,2024

Hippocampal study unveils distinct protein machineries for calcium channel clustering and vesicle priming

by Ingrid Fadelli , Medical XpressMunc13-1 and CaV2.1 nanoclustering. a–c, Example STED images of sideview synapses (a), quantification of line profiles (b) and Pearson's colocalization coefficien

Updated on: September 23,2024

Hippocampal study unveils distinct protein machineries for calcium channel clustering and vesicle priming

by Ingrid Fadelli , Medical XpressMunc13-1 and CaV2.1 nanoclustering. a–c, Example STED images of sideview synapses (a), quantification of line profiles (b) and Pearson's colocalization coefficien

Updated on:September 23,2024

Scientists find a determining mechanism for synapse formation in the cerebellum

byMiguel Hernandez University of ElcheExpansion microscopy image with synaptic boutons (green) of climbing fibers on a Purkinje cell (blue) from the cerebellum of a mouse. Credit: CC BY IN-CSIC-

Updated on: July 11,2024

Scientists find a determining mechanism for synapse formation in the cerebellum

byMiguel Hernandez University of ElcheExpansion microscopy image with synaptic boutons (green) of climbing fibers on a Purkinje cell (blue) from the cerebellum of a mouse. Credit: CC BY IN-CSIC-

Updated on:July 11,2024

Scientists uncover new molecular drivers of Alzheimer's

by The Scripps Research InstituteA tiny glass tube (top left) represents the electrode recording from an excitatory human Alzheimer's neuron, generated using modern stem cell techniques (dark

Updated on: June 15,2024

Scientists uncover new molecular drivers of Alzheimer's

by The Scripps Research InstituteA tiny glass tube (top left) represents the electrode recording from an excitatory human Alzheimer's neuron, generated using modern stem cell techniques (dark

Updated on:June 15,2024

APOE4 triggers early breakdowns in the blood-brain barrier

by University of Southern CaliforniaCredit: CC0 Public DomainNew USC research reveals how APOE4, a genetic culprit for Alzheimer's disease, triggers leaks in the brain's plumbing system,

Updated on: March 26,2024

APOE4 triggers early breakdowns in the blood-brain barrier

by University of Southern CaliforniaCredit: CC0 Public DomainNew USC research reveals how APOE4, a genetic culprit for Alzheimer's disease, triggers leaks in the brain's plumbing system,

Updated on:March 26,2024

Synthetic peptide can inhibit toxicity, aggregation of protein in Alzheimer's disease

by University of WashingtonPET scan of a human brain with Alzheimer's disease. Credit: public domainAlzheimer's is a disease of aggregation. Neurons in the human brain make a protein call

Updated on: June 07,2024

Synthetic peptide can inhibit toxicity, aggregation of protein in Alzheimer's disease

by University of WashingtonPET scan of a human brain with Alzheimer's disease. Credit: public domainAlzheimer's is a disease of aggregation. Neurons in the human brain make a protein call

Updated on:June 07,2024

For Alzheimer's patients, a controversial drug brings hope

by Hannah Critchfield and Kirby WilsonCredit: Pixabay/CC0 Public DomainAt 53, Michele Hall was at the height of her legal career. She'd just sent her three kids to college. She had decades ahead w

Updated on: May 26,2024

For Alzheimer's patients, a controversial drug brings hope

by Hannah Critchfield and Kirby WilsonCredit: Pixabay/CC0 Public DomainAt 53, Michele Hall was at the height of her legal career. She'd just sent her three kids to college. She had decades ahead w

Updated on:May 26,2024