Alzheimer's research with primates could address treatments that show promise in mice but don't help humans

by Agnès Lacreuse, Allyson J. Bennett and Amanda M. Dettmer,The ConversationRhesus macaques experience an aging process similar to people’s. Credit: Unsplash/CC0 Public DomainAs of 2022, an esti

Updated on: May 26,2024

Alzheimer's research with primates could address treatments that show promise in mice but don't help humans

by Agnès Lacreuse, Allyson J. Bennett and Amanda M. Dettmer,The ConversationRhesus macaques experience an aging process similar to people’s. Credit: Unsplash/CC0 Public DomainAs of 2022, an esti

Updated on:May 26,2024

Cell-type-specific genetic risk contributes to distinct stages of Alzheimer's disease progression, finds study

by Brigham and Women's HospitalCell-type-specific Alzheimer’s disease polygenic risk scores (ADPRS).aA schematic of cell-type-specific PRS derivation.bAn UpSetR plot o

Updated on: February 24,2024

Cell-type-specific genetic risk contributes to distinct stages of Alzheimer's disease progression, finds study

by Brigham and Women's HospitalCell-type-specific Alzheimer’s disease polygenic risk scores (ADPRS).aA schematic of cell-type-specific PRS derivation.bAn UpSetR plot o

Updated on:February 24,2024

Synthetic peptide can inhibit toxicity, aggregation of protein in Alzheimer's disease

by University of WashingtonPET scan of a human brain with Alzheimer's disease. Credit: public domainAlzheimer's is a disease of aggregation. Neurons in the human brain make a protein call

Updated on: June 07,2024

Synthetic peptide can inhibit toxicity, aggregation of protein in Alzheimer's disease

by University of WashingtonPET scan of a human brain with Alzheimer's disease. Credit: public domainAlzheimer's is a disease of aggregation. Neurons in the human brain make a protein call

Updated on:June 07,2024

Study shows DNA organization can influence the growth of deadly brain tumors in response to neuronal signals

by Gustav Löfgren,Swedish Research CouncilGene expression changes common to all four GB subtypes relate to synapse organization, glutamatergic synapses and chromatin binding (OPCs: oligodendrocy

Updated on: January 11,2024

Study shows DNA organization can influence the growth of deadly brain tumors in response to neuronal signals

by Gustav Löfgren,Swedish Research CouncilGene expression changes common to all four GB subtypes relate to synapse organization, glutamatergic synapses and chromatin binding (OPCs: oligodendrocy

Updated on:January 11,2024

Overlooked brain organ plays key role in promoting brain repair after stroke, researchers discover

byUniversity of CincinnatiFluorescent image of a healthy choroid plexus, the main producer of cerebrospinal fluid in the brain. Credit: Agnes (Yu) LuoUniversity of Cincinnati researchers have pi

Updated on: July 08,2024

Overlooked brain organ plays key role in promoting brain repair after stroke, researchers discover

byUniversity of CincinnatiFluorescent image of a healthy choroid plexus, the main producer of cerebrospinal fluid in the brain. Credit: Agnes (Yu) LuoUniversity of Cincinnati researchers have pi

Updated on:July 08,2024

Clinical trial suggests ALS drug effective for treating spinal cord injuries

by Laurie Fickman,University of HoustonRiluzole trough and peak concentrations from Phase I and Phase II/III trials presented in waterfall plots. Credit:Journal of Neurotrauma(2023).

Updated on: January 11,2024

Clinical trial suggests ALS drug effective for treating spinal cord injuries

by Laurie Fickman,University of HoustonRiluzole trough and peak concentrations from Phase I and Phase II/III trials presented in waterfall plots. Credit:Journal of Neurotrauma(2023).

Updated on:January 11,2024

Lipid-based diets effectively combat Alzheimer's disease in mouse model

by Bentham Science PublishersResearchers have devised several lipid-based diets aimed at slowing down progression and relieving symptoms of Alzheimer's disease. Credit: Janickova et al, Bentham Sc

Updated on: February 27,2024

Lipid-based diets effectively combat Alzheimer's disease in mouse model

by Bentham Science PublishersResearchers have devised several lipid-based diets aimed at slowing down progression and relieving symptoms of Alzheimer's disease. Credit: Janickova et al, Bentham Sc

Updated on:February 27,2024

Unlocking the mystery of tau for treatment of neurodegenerative diseases

by Nagoya UniversityUnder normal physiological conditions, FUS and SFPQ interact in the nucleus of nerve cells and regulate the alternative splicing of MAPT by excising exon 10. When this functio

Updated on: July 01,2024

Unlocking the mystery of tau for treatment of neurodegenerative diseases

by Nagoya UniversityUnder normal physiological conditions, FUS and SFPQ interact in the nucleus of nerve cells and regulate the alternative splicing of MAPT by excising exon 10. When this functio

Updated on:July 01,2024

Molecule reduces multiple pathologies associated with Alzheimer's disease

by Diana Yates,University of Illinois at Urbana-ChampaignWhen tested in a mouse model of Alzheimer's disease, a new compound, L1, reduced neuroinflammation, amyloid plaques and other molecul

Updated on: June 01,2024

Molecule reduces multiple pathologies associated with Alzheimer's disease

by Diana Yates,University of Illinois at Urbana-ChampaignWhen tested in a mouse model of Alzheimer's disease, a new compound, L1, reduced neuroinflammation, amyloid plaques and other molecul

Updated on:June 01,2024

Presence hallucinations: An early predictor of cognitive decline in Parkinson's disease

by Ecole Polytechnique Federale de LausanneEarly hallucinations in Parkinson's disease are associated with frontal cognitive decline (triangles), and preceded by specific frontal neural oscil

Updated on: February 18,2024

Presence hallucinations: An early predictor of cognitive decline in Parkinson's disease

by Ecole Polytechnique Federale de LausanneEarly hallucinations in Parkinson's disease are associated with frontal cognitive decline (triangles), and preceded by specific frontal neural oscil

Updated on:February 18,2024

Alzheimer's diagnosis, management improved by brain scans

by Alzheimer's AssociationAmyloid-positive (left) and amyloid-negative (right) PET scans can respectively be used to diagnose or rule out Alzheimer's disease in individuals with memory loss or

Updated on: April 25,2024

Alzheimer's diagnosis, management improved by brain scans

by Alzheimer's AssociationAmyloid-positive (left) and amyloid-negative (right) PET scans can respectively be used to diagnose or rule out Alzheimer's disease in individuals with memory loss or

Updated on:April 25,2024

Good news, bad news from Alzheimer's vaccine trial

by Marianne Madeiros and Robin FosterAn experimental Alzheimer's vaccine appears to safely clear abnormal tau protein from the brain, but it's not yet clear whether the shot will be able to sa

Updated on: April 16,2024

Good news, bad news from Alzheimer's vaccine trial

by Marianne Madeiros and Robin FosterAn experimental Alzheimer's vaccine appears to safely clear abnormal tau protein from the brain, but it's not yet clear whether the shot will be able to sa

Updated on:April 16,2024