Cell-type-specific genetic risk contributes to distinct stages of Alzheimer's disease progression, finds study

by Brigham and Women's HospitalCell-type-specific Alzheimer’s disease polygenic risk scores (ADPRS).aA schematic of cell-type-specific PRS derivation.bAn UpSetR plot o

Updated on: February 24,2024

Cell-type-specific genetic risk contributes to distinct stages of Alzheimer's disease progression, finds study

by Brigham and Women's HospitalCell-type-specific Alzheimer’s disease polygenic risk scores (ADPRS).aA schematic of cell-type-specific PRS derivation.bAn UpSetR plot o

Updated on:February 24,2024

Neuron populations in the medial prefrontal cortex shown to code the learning of avoidant behaviors

by Ingrid Fadelli , Medical XpressThe two-dimensional active avoidance paradigm and recording of prefrontal population activity. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024-0

Updated on: September 06,2024

Neuron populations in the medial prefrontal cortex shown to code the learning of avoidant behaviors

by Ingrid Fadelli , Medical XpressThe two-dimensional active avoidance paradigm and recording of prefrontal population activity. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024-0

Updated on:September 06,2024

Intensive trauma treatment relieves PTSD symptoms within eight days, finds researcher

by Radboud UniversityCredit: Unsplash/CC0 Public DomainRelieved from post-traumatic stress disorder symptoms in eight days? It is possible with a highly intensive treatment method that combines t

Updated on: March 19,2024

Intensive trauma treatment relieves PTSD symptoms within eight days, finds researcher

by Radboud UniversityCredit: Unsplash/CC0 Public DomainRelieved from post-traumatic stress disorder symptoms in eight days? It is possible with a highly intensive treatment method that combines t

Updated on:March 19,2024

How decision-making mechanisms go awry in OCD brains

by Maddie Massy-Westropp,University of New South WalesExperienced value—devaluation test results. Credit:Biological Psychiatry Global Open Science(2022). DOI: 10.1016/j.bpsgos.2022.1

Updated on: January 12,2024

How decision-making mechanisms go awry in OCD brains

by Maddie Massy-Westropp,University of New South WalesExperienced value—devaluation test results. Credit:Biological Psychiatry Global Open Science(2022). DOI: 10.1016/j.bpsgos.2022.1

Updated on:January 12,2024

How a mutation in microglia elevates Alzheimer's risk

byMassachusetts Institute of TechnologyBright green staining highlights human microglia implanted in the hippocampus region of the brain of a mouse. Credit: Jay Penney/MIT Picower InstituteA rar

Updated on: January 10,2024

How a mutation in microglia elevates Alzheimer's risk

byMassachusetts Institute of TechnologyBright green staining highlights human microglia implanted in the hippocampus region of the brain of a mouse. Credit: Jay Penney/MIT Picower InstituteA rar

Updated on:January 10,2024

Intermittent fasting could help protect the brain from age-related diseases like Alzheimer's

by Claudia Ntsapi,The ConversationCredit: AI-generated imageAs the world population hasgrown older, Alzheimer's disease has become increasingly common. Alzheimer's disease is the m

Updated on: June 20,2024

Intermittent fasting could help protect the brain from age-related diseases like Alzheimer's

by Claudia Ntsapi,The ConversationCredit: AI-generated imageAs the world population hasgrown older, Alzheimer's disease has become increasingly common. Alzheimer's disease is the m

Updated on:June 20,2024

5 ways to lower your chances of getting Alzheimer's

by University of Southern CaliforniaCredit: University of Southern CaliforniaRetain a sharp, healthy brain and reduce your risk of Alzheimer's disease by following five simple rules. Some of

Updated on: June 24,2024

5 ways to lower your chances of getting Alzheimer's

by University of Southern CaliforniaCredit: University of Southern CaliforniaRetain a sharp, healthy brain and reduce your risk of Alzheimer's disease by following five simple rules. Some of

Updated on:June 24,2024

Synthetic peptide can inhibit toxicity, aggregation of protein in Alzheimer's disease

by University of WashingtonPET scan of a human brain with Alzheimer's disease. Credit: public domainAlzheimer's is a disease of aggregation. Neurons in the human brain make a protein call

Updated on: June 07,2024

Synthetic peptide can inhibit toxicity, aggregation of protein in Alzheimer's disease

by University of WashingtonPET scan of a human brain with Alzheimer's disease. Credit: public domainAlzheimer's is a disease of aggregation. Neurons in the human brain make a protein call

Updated on:June 07,2024

Alzheimer's disease could be treated with gene therapy, animal study suggests

by Imperial College LondonBrain cells from a mouse cortex that didn't receive the gene therapy. The amyloid plaques are shown in green, and the glial cells, which surround the plaques, are sh

Updated on: May 22,2024

Alzheimer's disease could be treated with gene therapy, animal study suggests

by Imperial College LondonBrain cells from a mouse cortex that didn't receive the gene therapy. The amyloid plaques are shown in green, and the glial cells, which surround the plaques, are sh

Updated on:May 22,2024

Is a commonly-used screening tool for cognitive impairment accurate in diverse populations?

by WileyCredit: Pixabay/CC0 Public DomainA screening tool often used in primary care clinics to detect cognitive impairment has shortcomings when applied to ethnically and linguistically diverse

Updated on: February 24,2024

Is a commonly-used screening tool for cognitive impairment accurate in diverse populations?

by WileyCredit: Pixabay/CC0 Public DomainA screening tool often used in primary care clinics to detect cognitive impairment has shortcomings when applied to ethnically and linguistically diverse

Updated on:February 24,2024

APOE4 triggers early breakdowns in the blood-brain barrier

by University of Southern CaliforniaCredit: CC0 Public DomainNew USC research reveals how APOE4, a genetic culprit for Alzheimer's disease, triggers leaks in the brain's plumbing system,

Updated on: March 26,2024

APOE4 triggers early breakdowns in the blood-brain barrier

by University of Southern CaliforniaCredit: CC0 Public DomainNew USC research reveals how APOE4, a genetic culprit for Alzheimer's disease, triggers leaks in the brain's plumbing system,

Updated on:March 26,2024

Tips to protect long-term brain health

by Tufts UniversityCredit: AI-generated imageThere is a growing understanding of the role lifestyle choices play in preventing and slowing the progression of cognitive decline. While we await new

Updated on: March 02,2024

Tips to protect long-term brain health

by Tufts UniversityCredit: AI-generated imageThere is a growing understanding of the role lifestyle choices play in preventing and slowing the progression of cognitive decline. While we await new

Updated on:March 02,2024