Cell-type-specific genetic risk contributes to distinct stages of Alzheimer's disease progression, finds study

by Brigham and Women's HospitalCell-type-specific Alzheimer’s disease polygenic risk scores (ADPRS).aA schematic of cell-type-specific PRS derivation.bAn UpSetR plot o

Updated on: February 24,2024

Cell-type-specific genetic risk contributes to distinct stages of Alzheimer's disease progression, finds study

by Brigham and Women's HospitalCell-type-specific Alzheimer’s disease polygenic risk scores (ADPRS).aA schematic of cell-type-specific PRS derivation.bAn UpSetR plot o

Updated on:February 24,2024

Is a commonly-used screening tool for cognitive impairment accurate in diverse populations?

by WileyCredit: Pixabay/CC0 Public DomainA screening tool often used in primary care clinics to detect cognitive impairment has shortcomings when applied to ethnically and linguistically diverse

Updated on: February 24,2024

Is a commonly-used screening tool for cognitive impairment accurate in diverse populations?

by WileyCredit: Pixabay/CC0 Public DomainA screening tool often used in primary care clinics to detect cognitive impairment has shortcomings when applied to ethnically and linguistically diverse

Updated on:February 24,2024

A wave theory for explaining neurochemical balance in the brain

byHebrew University of JerusalemAcetylcholine wave traveling from lateral (L) to medial (M) in the striatum Credit: Dr. Joshua Goldberg, Prof. Jeffery Wickens, Dr. Nicolas TristchIn a new study,

Updated on: January 12,2024

A wave theory for explaining neurochemical balance in the brain

byHebrew University of JerusalemAcetylcholine wave traveling from lateral (L) to medial (M) in the striatum Credit: Dr. Joshua Goldberg, Prof. Jeffery Wickens, Dr. Nicolas TristchIn a new study,

Updated on:January 12,2024

Alzheimer's disease could be treated with gene therapy, animal study suggests

by Imperial College LondonBrain cells from a mouse cortex that didn't receive the gene therapy. The amyloid plaques are shown in green, and the glial cells, which surround the plaques, are sh

Updated on: May 22,2024

Alzheimer's disease could be treated with gene therapy, animal study suggests

by Imperial College LondonBrain cells from a mouse cortex that didn't receive the gene therapy. The amyloid plaques are shown in green, and the glial cells, which surround the plaques, are sh

Updated on:May 22,2024

Individuals with high Alzheimer's risk may use attention to process, rather than suppress, distracting stimuli

by California Institute of TechnologyPractice makes imperfect: stronger implicit interference with practice in individuals at high risk of developing Alzheimer’s disease. An example trial sequenc

Updated on: February 24,2024

Individuals with high Alzheimer's risk may use attention to process, rather than suppress, distracting stimuli

by California Institute of TechnologyPractice makes imperfect: stronger implicit interference with practice in individuals at high risk of developing Alzheimer’s disease. An example trial sequenc

Updated on:February 24,2024

Eating lots of 'ultra-processed' foods could harm your brain

by Steven ReinbergChips, pizza, cookies: Delicious, but a diet full of ultra-processed foods like these may contribute to brain deterioration, researchers report.Ultra-processed foods have lots of add

Updated on: February 05,2024

Eating lots of 'ultra-processed' foods could harm your brain

by Steven ReinbergChips, pizza, cookies: Delicious, but a diet full of ultra-processed foods like these may contribute to brain deterioration, researchers report.Ultra-processed foods have lots of add

Updated on:February 05,2024

Maria shriver and AARP take on Alzheimer's in women

by Serena Gordon, Healthday ReporterMaria Shriver(HealthDay)—An Alzheimer's diagnosis is devastating, no matter your sex. But the disease strikes far more women than men.Journalist and author Mari

Updated on: March 30,2024

Maria shriver and AARP take on Alzheimer's in women

by Serena Gordon, Healthday ReporterMaria Shriver(HealthDay)—An Alzheimer's diagnosis is devastating, no matter your sex. But the disease strikes far more women than men.Journalist and author Mari

Updated on:March 30,2024

Tool to measure brain blood flow identifies tell-tale signs of dementia and Alzheimer's early

by COSTCredit: COSTA network of over 200 scientists, clinicians and industry partners developed a cost-effective diagnostic tool for measuring the tell-tale signs of dementia and Alzheimer's. The

Updated on: May 05,2024

Tool to measure brain blood flow identifies tell-tale signs of dementia and Alzheimer's early

by COSTCredit: COSTA network of over 200 scientists, clinicians and industry partners developed a cost-effective diagnostic tool for measuring the tell-tale signs of dementia and Alzheimer's. The

Updated on:May 05,2024

Living with Alzheimer's: China's health time bomb

Credit: CC0 Public DomainThe first time Chen Shaohua went missing and was picked up by police, the 68-year-old's family put it down to confusion.When he disappeared a second time, they realised he

Updated on: April 25,2024

Living with Alzheimer's: China's health time bomb

Credit: CC0 Public DomainThe first time Chen Shaohua went missing and was picked up by police, the 68-year-old's family put it down to confusion.When he disappeared a second time, they realised he

Updated on:April 25,2024

Scientists find a determining mechanism for synapse formation in the cerebellum

byMiguel Hernandez University of ElcheExpansion microscopy image with synaptic boutons (green) of climbing fibers on a Purkinje cell (blue) from the cerebellum of a mouse. Credit: CC BY IN-CSIC-

Updated on: July 11,2024

Scientists find a determining mechanism for synapse formation in the cerebellum

byMiguel Hernandez University of ElcheExpansion microscopy image with synaptic boutons (green) of climbing fibers on a Purkinje cell (blue) from the cerebellum of a mouse. Credit: CC BY IN-CSIC-

Updated on:July 11,2024

Unlocking the mystery of tau for treatment of neurodegenerative diseases

by Nagoya UniversityUnder normal physiological conditions, FUS and SFPQ interact in the nucleus of nerve cells and regulate the alternative splicing of MAPT by excising exon 10. When this functio

Updated on: July 01,2024

Unlocking the mystery of tau for treatment of neurodegenerative diseases

by Nagoya UniversityUnder normal physiological conditions, FUS and SFPQ interact in the nucleus of nerve cells and regulate the alternative splicing of MAPT by excising exon 10. When this functio

Updated on:July 01,2024

For Alzheimer's patients, a controversial drug brings hope

by Hannah Critchfield and Kirby WilsonCredit: Pixabay/CC0 Public DomainAt 53, Michele Hall was at the height of her legal career. She'd just sent her three kids to college. She had decades ahead w

Updated on: May 26,2024

For Alzheimer's patients, a controversial drug brings hope

by Hannah Critchfield and Kirby WilsonCredit: Pixabay/CC0 Public DomainAt 53, Michele Hall was at the height of her legal career. She'd just sent her three kids to college. She had decades ahead w

Updated on:May 26,2024