Unlocking the mystery of tau for treatment of neurodegenerative diseases

by Nagoya UniversityUnder normal physiological conditions, FUS and SFPQ interact in the nucleus of nerve cells and regulate the alternative splicing of MAPT by excising exon 10. When this functio

Updated on: July 01,2024

Unlocking the mystery of tau for treatment of neurodegenerative diseases

by Nagoya UniversityUnder normal physiological conditions, FUS and SFPQ interact in the nucleus of nerve cells and regulate the alternative splicing of MAPT by excising exon 10. When this functio

Updated on:July 01,2024

Maria shriver and AARP take on Alzheimer's in women

by Serena Gordon, Healthday ReporterMaria Shriver(HealthDay)—An Alzheimer's diagnosis is devastating, no matter your sex. But the disease strikes far more women than men.Journalist and author Mari

Updated on: March 30,2024

Maria shriver and AARP take on Alzheimer's in women

by Serena Gordon, Healthday ReporterMaria Shriver(HealthDay)—An Alzheimer's diagnosis is devastating, no matter your sex. But the disease strikes far more women than men.Journalist and author Mari

Updated on:March 30,2024

For Alzheimer's patients, a controversial drug brings hope

by Hannah Critchfield and Kirby WilsonCredit: Pixabay/CC0 Public DomainAt 53, Michele Hall was at the height of her legal career. She'd just sent her three kids to college. She had decades ahead w

Updated on: May 26,2024

For Alzheimer's patients, a controversial drug brings hope

by Hannah Critchfield and Kirby WilsonCredit: Pixabay/CC0 Public DomainAt 53, Michele Hall was at the height of her legal career. She'd just sent her three kids to college. She had decades ahead w

Updated on:May 26,2024

Traumatic memories can rewire the brain: Study

by National Institutes of Natural SciencesDetecting learning-dependent changes in neural networks to understand how memory is made in the prefrontal region of the brain. Credit: Masakazu Agetsuma

Updated on: February 05,2024

Traumatic memories can rewire the brain: Study

by National Institutes of Natural SciencesDetecting learning-dependent changes in neural networks to understand how memory is made in the prefrontal region of the brain. Credit: Masakazu Agetsuma

Updated on:February 05,2024

Lipid-based diets effectively combat Alzheimer's disease in mouse model

by Bentham Science PublishersResearchers have devised several lipid-based diets aimed at slowing down progression and relieving symptoms of Alzheimer's disease. Credit: Janickova et al, Bentham Sc

Updated on: February 27,2024

Lipid-based diets effectively combat Alzheimer's disease in mouse model

by Bentham Science PublishersResearchers have devised several lipid-based diets aimed at slowing down progression and relieving symptoms of Alzheimer's disease. Credit: Janickova et al, Bentham Sc

Updated on:February 27,2024

Researchers identify neurons responsible for key activity transition in brain development

byKing's College LondonCredit:Neuron(2024). DOI: 10.1016/j.neuron.2024.03.014Scientists at the Center for Developmental Neurobiology and MRC Center for Neurodevelopmental Disorde

Updated on: April 28,2024

Researchers identify neurons responsible for key activity transition in brain development

byKing's College LondonCredit:Neuron(2024). DOI: 10.1016/j.neuron.2024.03.014Scientists at the Center for Developmental Neurobiology and MRC Center for Neurodevelopmental Disorde

Updated on:April 28,2024

Silencing a faulty gene may uncover clues to rare forms of ALS

by National Institutes of HealthCredit: Pixabay/CC0 Public DomainUsing an experimental drug, researchers have been able to suppress a mutated amyotrophic lateral sclerosis (ALS) gene. Studies in

Updated on: February 05,2024

Silencing a faulty gene may uncover clues to rare forms of ALS

by National Institutes of HealthCredit: Pixabay/CC0 Public DomainUsing an experimental drug, researchers have been able to suppress a mutated amyotrophic lateral sclerosis (ALS) gene. Studies in

Updated on:February 05,2024

Early diagnosis of Alzheimer's: Ultra-long protein fibrils give clues on dementia risk

by Swiss Federal Laboratories for Materials Science and TechnologyAtomic force microscopy: Peter Nirmalraj investigates Alzheimer's disease at the nanometer scale. Credit: EmpaThe early detec

Updated on: April 18,2024

Early diagnosis of Alzheimer's: Ultra-long protein fibrils give clues on dementia risk

by Swiss Federal Laboratories for Materials Science and TechnologyAtomic force microscopy: Peter Nirmalraj investigates Alzheimer's disease at the nanometer scale. Credit: EmpaThe early detec

Updated on:April 18,2024

Living with Alzheimer's: China's health time bomb

Credit: CC0 Public DomainThe first time Chen Shaohua went missing and was picked up by police, the 68-year-old's family put it down to confusion.When he disappeared a second time, they realised he

Updated on: April 25,2024

Living with Alzheimer's: China's health time bomb

Credit: CC0 Public DomainThe first time Chen Shaohua went missing and was picked up by police, the 68-year-old's family put it down to confusion.When he disappeared a second time, they realised he

Updated on:April 25,2024

Synthetic peptide can inhibit toxicity, aggregation of protein in Alzheimer's disease

by University of WashingtonPET scan of a human brain with Alzheimer's disease. Credit: public domainAlzheimer's is a disease of aggregation. Neurons in the human brain make a protein call

Updated on: June 07,2024

Synthetic peptide can inhibit toxicity, aggregation of protein in Alzheimer's disease

by University of WashingtonPET scan of a human brain with Alzheimer's disease. Credit: public domainAlzheimer's is a disease of aggregation. Neurons in the human brain make a protein call

Updated on:June 07,2024

Identifying typical patterns in the progression towards Alzheimer's disease

by University of MontrealHow the brain progresses from mild cognitive impairment (MCI) to Alzheimer's-type dementia has been an enigma for the scientific community. However, a recent study by

Updated on: February 26,2024

Identifying typical patterns in the progression towards Alzheimer's disease

by University of MontrealHow the brain progresses from mild cognitive impairment (MCI) to Alzheimer's-type dementia has been an enigma for the scientific community. However, a recent study by

Updated on:February 26,2024

New insights into the development of Parkinson's disease in the brain might open the doors to new therapies

byTokyo Medical and Dental UniversityIn healthy condition, CHCHD2WT localizes in mitochondria. In pathogenic condition, mutant CHCHD2T61I mislocalizes to the cytosol and recruits Casein kinase 1

Updated on: March 14,2024

New insights into the development of Parkinson's disease in the brain might open the doors to new therapies

byTokyo Medical and Dental UniversityIn healthy condition, CHCHD2WT localizes in mitochondria. In pathogenic condition, mutant CHCHD2T61I mislocalizes to the cytosol and recruits Casein kinase 1

Updated on:March 14,2024