Synthetic peptide can inhibit toxicity, aggregation of protein in Alzheimer's disease

by University of WashingtonPET scan of a human brain with Alzheimer's disease. Credit: public domainAlzheimer's is a disease of aggregation. Neurons in the human brain make a protein call

Updated on: June 07,2024

Synthetic peptide can inhibit toxicity, aggregation of protein in Alzheimer's disease

by University of WashingtonPET scan of a human brain with Alzheimer's disease. Credit: public domainAlzheimer's is a disease of aggregation. Neurons in the human brain make a protein call

Updated on:June 07,2024

Unlocking the mystery of tau for treatment of neurodegenerative diseases

by Nagoya UniversityUnder normal physiological conditions, FUS and SFPQ interact in the nucleus of nerve cells and regulate the alternative splicing of MAPT by excising exon 10. When this functio

Updated on: July 01,2024

Unlocking the mystery of tau for treatment of neurodegenerative diseases

by Nagoya UniversityUnder normal physiological conditions, FUS and SFPQ interact in the nucleus of nerve cells and regulate the alternative splicing of MAPT by excising exon 10. When this functio

Updated on:July 01,2024

Alzheimer's disease could be treated with gene therapy, animal study suggests

by Imperial College LondonBrain cells from a mouse cortex that didn't receive the gene therapy. The amyloid plaques are shown in green, and the glial cells, which surround the plaques, are sh

Updated on: May 22,2024

Alzheimer's disease could be treated with gene therapy, animal study suggests

by Imperial College LondonBrain cells from a mouse cortex that didn't receive the gene therapy. The amyloid plaques are shown in green, and the glial cells, which surround the plaques, are sh

Updated on:May 22,2024

Is Alzheimer's caused by disruptions to the brain's energy supply?

by Kira Shaw And Orla Bonnar,The ConversationCredit: AI-generated imageIt is well known that Alzheimer's disease, the most common form of dementia, involves the accumulation of sticky protei

Updated on: April 20,2024

Is Alzheimer's caused by disruptions to the brain's energy supply?

by Kira Shaw And Orla Bonnar,The ConversationCredit: AI-generated imageIt is well known that Alzheimer's disease, the most common form of dementia, involves the accumulation of sticky protei

Updated on:April 20,2024

A wave theory for explaining neurochemical balance in the brain

byHebrew University of JerusalemAcetylcholine wave traveling from lateral (L) to medial (M) in the striatum Credit: Dr. Joshua Goldberg, Prof. Jeffery Wickens, Dr. Nicolas TristchIn a new study,

Updated on: January 12,2024

A wave theory for explaining neurochemical balance in the brain

byHebrew University of JerusalemAcetylcholine wave traveling from lateral (L) to medial (M) in the striatum Credit: Dr. Joshua Goldberg, Prof. Jeffery Wickens, Dr. Nicolas TristchIn a new study,

Updated on:January 12,2024

Early diagnosis of Alzheimer's: Ultra-long protein fibrils give clues on dementia risk

by Swiss Federal Laboratories for Materials Science and TechnologyAtomic force microscopy: Peter Nirmalraj investigates Alzheimer's disease at the nanometer scale. Credit: EmpaThe early detec

Updated on: April 18,2024

Early diagnosis of Alzheimer's: Ultra-long protein fibrils give clues on dementia risk

by Swiss Federal Laboratories for Materials Science and TechnologyAtomic force microscopy: Peter Nirmalraj investigates Alzheimer's disease at the nanometer scale. Credit: EmpaThe early detec

Updated on:April 18,2024

Alzheimer's research with primates could address treatments that show promise in mice but don't help humans

by Agnès Lacreuse, Allyson J. Bennett and Amanda M. Dettmer,The ConversationRhesus macaques experience an aging process similar to people’s. Credit: Unsplash/CC0 Public DomainAs of 2022, an esti

Updated on: May 26,2024

Alzheimer's research with primates could address treatments that show promise in mice but don't help humans

by Agnès Lacreuse, Allyson J. Bennett and Amanda M. Dettmer,The ConversationRhesus macaques experience an aging process similar to people’s. Credit: Unsplash/CC0 Public DomainAs of 2022, an esti

Updated on:May 26,2024

How our brains learn new athletic skills fast: Investigating electrocortical activity and faster locomotor adaptation

byUniversity of FloridaVisual Overview. Credit:eneuro(2024). DOI: 10.1523/ENEURO.0515-23.2024You join a swing dance class, and at first you're all left feet. But—slowly, eyes glu

Updated on: July 31,2024

How our brains learn new athletic skills fast: Investigating electrocortical activity and faster locomotor adaptation

byUniversity of FloridaVisual Overview. Credit:eneuro(2024). DOI: 10.1523/ENEURO.0515-23.2024You join a swing dance class, and at first you're all left feet. But—slowly, eyes glu

Updated on:July 31,2024

Lipid-based diets effectively combat Alzheimer's disease in mouse model

by Bentham Science PublishersResearchers have devised several lipid-based diets aimed at slowing down progression and relieving symptoms of Alzheimer's disease. Credit: Janickova et al, Bentham Sc

Updated on: February 27,2024

Lipid-based diets effectively combat Alzheimer's disease in mouse model

by Bentham Science PublishersResearchers have devised several lipid-based diets aimed at slowing down progression and relieving symptoms of Alzheimer's disease. Credit: Janickova et al, Bentham Sc

Updated on:February 27,2024

Researchers identify neurons responsible for key activity transition in brain development

byKing's College LondonCredit:Neuron(2024). DOI: 10.1016/j.neuron.2024.03.014Scientists at the Center for Developmental Neurobiology and MRC Center for Neurodevelopmental Disorde

Updated on: April 28,2024

Researchers identify neurons responsible for key activity transition in brain development

byKing's College LondonCredit:Neuron(2024). DOI: 10.1016/j.neuron.2024.03.014Scientists at the Center for Developmental Neurobiology and MRC Center for Neurodevelopmental Disorde

Updated on:April 28,2024

New insights into the development of Parkinson's disease in the brain might open the doors to new therapies

byTokyo Medical and Dental UniversityIn healthy condition, CHCHD2WT localizes in mitochondria. In pathogenic condition, mutant CHCHD2T61I mislocalizes to the cytosol and recruits Casein kinase 1

Updated on: March 14,2024

New insights into the development of Parkinson's disease in the brain might open the doors to new therapies

byTokyo Medical and Dental UniversityIn healthy condition, CHCHD2WT localizes in mitochondria. In pathogenic condition, mutant CHCHD2T61I mislocalizes to the cytosol and recruits Casein kinase 1

Updated on:March 14,2024

How being friends with someone who has dementia can be good for you both

by Janelle Taylor,The ConversationCredit: AI-generated imageEach year, in the final few hours of the last day of December, many people all across North America gather with friends to raise a gla

Updated on: June 07,2024

How being friends with someone who has dementia can be good for you both

by Janelle Taylor,The ConversationCredit: AI-generated imageEach year, in the final few hours of the last day of December, many people all across North America gather with friends to raise a gla

Updated on:June 07,2024