Alzheimer's disease could be treated with gene therapy, animal study suggests

by Imperial College LondonBrain cells from a mouse cortex that didn't receive the gene therapy. The amyloid plaques are shown in green, and the glial cells, which surround the plaques, are sh

Updated on: May 22,2024

Alzheimer's disease could be treated with gene therapy, animal study suggests

by Imperial College LondonBrain cells from a mouse cortex that didn't receive the gene therapy. The amyloid plaques are shown in green, and the glial cells, which surround the plaques, are sh

Updated on:May 22,2024

Study shows DNA organization can influence the growth of deadly brain tumors in response to neuronal signals

by Gustav Löfgren,Swedish Research CouncilGene expression changes common to all four GB subtypes relate to synapse organization, glutamatergic synapses and chromatin binding (OPCs: oligodendrocy

Updated on: January 11,2024

Study shows DNA organization can influence the growth of deadly brain tumors in response to neuronal signals

by Gustav Löfgren,Swedish Research CouncilGene expression changes common to all four GB subtypes relate to synapse organization, glutamatergic synapses and chromatin binding (OPCs: oligodendrocy

Updated on:January 11,2024

Overlooked brain organ plays key role in promoting brain repair after stroke, researchers discover

byUniversity of CincinnatiFluorescent image of a healthy choroid plexus, the main producer of cerebrospinal fluid in the brain. Credit: Agnes (Yu) LuoUniversity of Cincinnati researchers have pi

Updated on: July 08,2024

Overlooked brain organ plays key role in promoting brain repair after stroke, researchers discover

byUniversity of CincinnatiFluorescent image of a healthy choroid plexus, the main producer of cerebrospinal fluid in the brain. Credit: Agnes (Yu) LuoUniversity of Cincinnati researchers have pi

Updated on:July 08,2024

Brain damage study reveals part of the brain necessary for helping others

byUniversity of BirminghamCredit: CC0 Public DomainOur willingness to help others is governed by a specific brain region pinpointed by researchers in a study of patients with brain damage to tha

Updated on: May 30,2024

Brain damage study reveals part of the brain necessary for helping others

byUniversity of BirminghamCredit: CC0 Public DomainOur willingness to help others is governed by a specific brain region pinpointed by researchers in a study of patients with brain damage to tha

Updated on:May 30,2024

Clinical trial suggests ALS drug effective for treating spinal cord injuries

by Laurie Fickman,University of HoustonRiluzole trough and peak concentrations from Phase I and Phase II/III trials presented in waterfall plots. Credit:Journal of Neurotrauma(2023).

Updated on: January 11,2024

Clinical trial suggests ALS drug effective for treating spinal cord injuries

by Laurie Fickman,University of HoustonRiluzole trough and peak concentrations from Phase I and Phase II/III trials presented in waterfall plots. Credit:Journal of Neurotrauma(2023).

Updated on:January 11,2024

Presence hallucinations: An early predictor of cognitive decline in Parkinson's disease

by Ecole Polytechnique Federale de LausanneEarly hallucinations in Parkinson's disease are associated with frontal cognitive decline (triangles), and preceded by specific frontal neural oscil

Updated on: February 18,2024

Presence hallucinations: An early predictor of cognitive decline in Parkinson's disease

by Ecole Polytechnique Federale de LausanneEarly hallucinations in Parkinson's disease are associated with frontal cognitive decline (triangles), and preceded by specific frontal neural oscil

Updated on:February 18,2024

Good news, bad news from Alzheimer's vaccine trial

by Marianne Madeiros and Robin FosterAn experimental Alzheimer's vaccine appears to safely clear abnormal tau protein from the brain, but it's not yet clear whether the shot will be able to sa

Updated on: April 16,2024

Good news, bad news from Alzheimer's vaccine trial

by Marianne Madeiros and Robin FosterAn experimental Alzheimer's vaccine appears to safely clear abnormal tau protein from the brain, but it's not yet clear whether the shot will be able to sa

Updated on:April 16,2024

Synthetic peptide can inhibit toxicity, aggregation of protein in Alzheimer's disease

by University of WashingtonPET scan of a human brain with Alzheimer's disease. Credit: public domainAlzheimer's is a disease of aggregation. Neurons in the human brain make a protein call

Updated on: June 07,2024

Synthetic peptide can inhibit toxicity, aggregation of protein in Alzheimer's disease

by University of WashingtonPET scan of a human brain with Alzheimer's disease. Credit: public domainAlzheimer's is a disease of aggregation. Neurons in the human brain make a protein call

Updated on:June 07,2024

Researchers uncover shared cellular mechanisms across three major dementias

byUniversity of California, Los AngelesCredit: Pixabay/CC0 Public DomainResearchers have for the first time identified degeneration-associated "molecular markers"—observable changes in

Updated on: September 15,2024

Researchers uncover shared cellular mechanisms across three major dementias

byUniversity of California, Los AngelesCredit: Pixabay/CC0 Public DomainResearchers have for the first time identified degeneration-associated "molecular markers"—observable changes in

Updated on:September 15,2024

Molecule reduces multiple pathologies associated with Alzheimer's disease

by Diana Yates,University of Illinois at Urbana-ChampaignWhen tested in a mouse model of Alzheimer's disease, a new compound, L1, reduced neuroinflammation, amyloid plaques and other molecul

Updated on: June 01,2024

Molecule reduces multiple pathologies associated with Alzheimer's disease

by Diana Yates,University of Illinois at Urbana-ChampaignWhen tested in a mouse model of Alzheimer's disease, a new compound, L1, reduced neuroinflammation, amyloid plaques and other molecul

Updated on:June 01,2024

Lipid-based diets effectively combat Alzheimer's disease in mouse model

by Bentham Science PublishersResearchers have devised several lipid-based diets aimed at slowing down progression and relieving symptoms of Alzheimer's disease. Credit: Janickova et al, Bentham Sc

Updated on: February 27,2024

Lipid-based diets effectively combat Alzheimer's disease in mouse model

by Bentham Science PublishersResearchers have devised several lipid-based diets aimed at slowing down progression and relieving symptoms of Alzheimer's disease. Credit: Janickova et al, Bentham Sc

Updated on:February 27,2024

Unlocking the mystery of tau for treatment of neurodegenerative diseases

by Nagoya UniversityUnder normal physiological conditions, FUS and SFPQ interact in the nucleus of nerve cells and regulate the alternative splicing of MAPT by excising exon 10. When this functio

Updated on: July 01,2024

Unlocking the mystery of tau for treatment of neurodegenerative diseases

by Nagoya UniversityUnder normal physiological conditions, FUS and SFPQ interact in the nucleus of nerve cells and regulate the alternative splicing of MAPT by excising exon 10. When this functio

Updated on:July 01,2024