For Alzheimer's patients, a controversial drug brings hope

by Hannah Critchfield and Kirby WilsonCredit: Pixabay/CC0 Public DomainAt 53, Michele Hall was at the height of her legal career. She'd just sent her three kids to college. She had decades ahead w

Updated on: May 26,2024

For Alzheimer's patients, a controversial drug brings hope

by Hannah Critchfield and Kirby WilsonCredit: Pixabay/CC0 Public DomainAt 53, Michele Hall was at the height of her legal career. She'd just sent her three kids to college. She had decades ahead w

Updated on:May 26,2024

Couples and young-onset dementia: Study of coping offers hope for new interventions

by Massachusetts General HospitalCredit: CC0 Public DomainResearchers from Massachusetts General Hospital (MGH) have used a couples-based framework to describe the experiences of individuals diag

Updated on: June 01,2024

Couples and young-onset dementia: Study of coping offers hope for new interventions

by Massachusetts General HospitalCredit: CC0 Public DomainResearchers from Massachusetts General Hospital (MGH) have used a couples-based framework to describe the experiences of individuals diag

Updated on:June 01,2024

Cell-type-specific genetic risk contributes to distinct stages of Alzheimer's disease progression, finds study

by Brigham and Women's HospitalCell-type-specific Alzheimer’s disease polygenic risk scores (ADPRS).aA schematic of cell-type-specific PRS derivation.bAn UpSetR plot o

Updated on: February 24,2024

Cell-type-specific genetic risk contributes to distinct stages of Alzheimer's disease progression, finds study

by Brigham and Women's HospitalCell-type-specific Alzheimer’s disease polygenic risk scores (ADPRS).aA schematic of cell-type-specific PRS derivation.bAn UpSetR plot o

Updated on:February 24,2024

Is a commonly-used screening tool for cognitive impairment accurate in diverse populations?

by WileyCredit: Pixabay/CC0 Public DomainA screening tool often used in primary care clinics to detect cognitive impairment has shortcomings when applied to ethnically and linguistically diverse

Updated on: February 24,2024

Is a commonly-used screening tool for cognitive impairment accurate in diverse populations?

by WileyCredit: Pixabay/CC0 Public DomainA screening tool often used in primary care clinics to detect cognitive impairment has shortcomings when applied to ethnically and linguistically diverse

Updated on:February 24,2024

APOE4 triggers early breakdowns in the blood-brain barrier

by University of Southern CaliforniaCredit: CC0 Public DomainNew USC research reveals how APOE4, a genetic culprit for Alzheimer's disease, triggers leaks in the brain's plumbing system,

Updated on: March 26,2024

APOE4 triggers early breakdowns in the blood-brain barrier

by University of Southern CaliforniaCredit: CC0 Public DomainNew USC research reveals how APOE4, a genetic culprit for Alzheimer's disease, triggers leaks in the brain's plumbing system,

Updated on:March 26,2024

Down syndrome carries raised risk of dementia by 55

(HealthDay)—Most people with Down syndrome have dementia by age 55, a new study shows.People with Down syndrome are born with an extra copy of chromosome 21, which often results in developmental disab

Updated on: June 07,2024

Down syndrome carries raised risk of dementia by 55

(HealthDay)—Most people with Down syndrome have dementia by age 55, a new study shows.People with Down syndrome are born with an extra copy of chromosome 21, which often results in developmental disab

Updated on:June 07,2024

Intermittent fasting could help protect the brain from age-related diseases like Alzheimer's

by Claudia Ntsapi,The ConversationCredit: AI-generated imageAs the world population hasgrown older, Alzheimer's disease has become increasingly common. Alzheimer's disease is the m

Updated on: June 20,2024

Intermittent fasting could help protect the brain from age-related diseases like Alzheimer's

by Claudia Ntsapi,The ConversationCredit: AI-generated imageAs the world population hasgrown older, Alzheimer's disease has become increasingly common. Alzheimer's disease is the m

Updated on:June 20,2024

Alzheimer's disease could be treated with gene therapy, animal study suggests

by Imperial College LondonBrain cells from a mouse cortex that didn't receive the gene therapy. The amyloid plaques are shown in green, and the glial cells, which surround the plaques, are sh

Updated on: May 22,2024

Alzheimer's disease could be treated with gene therapy, animal study suggests

by Imperial College LondonBrain cells from a mouse cortex that didn't receive the gene therapy. The amyloid plaques are shown in green, and the glial cells, which surround the plaques, are sh

Updated on:May 22,2024

Neuron populations in the medial prefrontal cortex shown to code the learning of avoidant behaviors

by Ingrid Fadelli , Medical XpressThe two-dimensional active avoidance paradigm and recording of prefrontal population activity. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024-0

Updated on: September 06,2024

Neuron populations in the medial prefrontal cortex shown to code the learning of avoidant behaviors

by Ingrid Fadelli , Medical XpressThe two-dimensional active avoidance paradigm and recording of prefrontal population activity. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024-0

Updated on:September 06,2024

Study: Age-related alterations in the oscillatory dynamics serving verbal working memory processing

by Impact Journals LLCEffect of age on alpha and beta oscillations during the encoding, maintenance, and retrieval phases. Credit: 2023 Springer et al.A new research paper was published on the cover o

Updated on: January 09,2024

Study: Age-related alterations in the oscillatory dynamics serving verbal working memory processing

by Impact Journals LLCEffect of age on alpha and beta oscillations during the encoding, maintenance, and retrieval phases. Credit: 2023 Springer et al.A new research paper was published on the cover o

Updated on:January 09,2024

Synthetic peptide can inhibit toxicity, aggregation of protein in Alzheimer's disease

by University of WashingtonPET scan of a human brain with Alzheimer's disease. Credit: public domainAlzheimer's is a disease of aggregation. Neurons in the human brain make a protein call

Updated on: June 07,2024

Synthetic peptide can inhibit toxicity, aggregation of protein in Alzheimer's disease

by University of WashingtonPET scan of a human brain with Alzheimer's disease. Credit: public domainAlzheimer's is a disease of aggregation. Neurons in the human brain make a protein call

Updated on:June 07,2024

How a mutation in microglia elevates Alzheimer's risk

byMassachusetts Institute of TechnologyBright green staining highlights human microglia implanted in the hippocampus region of the brain of a mouse. Credit: Jay Penney/MIT Picower InstituteA rar

Updated on: January 10,2024

How a mutation in microglia elevates Alzheimer's risk

byMassachusetts Institute of TechnologyBright green staining highlights human microglia implanted in the hippocampus region of the brain of a mouse. Credit: Jay Penney/MIT Picower InstituteA rar

Updated on:January 10,2024