Problems finding your way around may be earliest sign of Alzheimer's disease

by Gerry Everding,Washington University in St. LouisA bird's-eye view of a virtual maze layout used in a study of how cognitive mapping and wayfinding skills are compromised in early stages

Updated on: February 28,2024 11

Problems finding your way around may be earliest sign of Alzheimer's disease

by Gerry Everding,Washington University in St. LouisA bird's-eye view of a virtual maze layout used in a study of how cognitive mapping and wayfinding skills are compromised in early stages

Updated on:February 28,2024 11

Genome-wide transcriptome profiling and development of age prediction models in the human brain

by Impact Journals LLCDifferential gene expression analysis overall and by sex. Credit:Aging(2024). DOI: 10.18632/aging.205609A new research paper was published inAgingentitled

Updated on: March 19,2024 10

Genome-wide transcriptome profiling and development of age prediction models in the human brain

by Impact Journals LLCDifferential gene expression analysis overall and by sex. Credit:Aging(2024). DOI: 10.18632/aging.205609A new research paper was published inAgingentitled

Updated on:March 19,2024 10

Digital detection of dementia: Using AI to identify undiagnosed cases

by Regenstrief InstituteOur two trials are highly pragmatic as indicated by scores of 4 and 5 (‘most pragmatic’) in the PRECIS-2 summary wheel depicted here. The diverse primary care settings, mi

Updated on: May 06,2024 14

Digital detection of dementia: Using AI to identify undiagnosed cases

by Regenstrief InstituteOur two trials are highly pragmatic as indicated by scores of 4 and 5 (‘most pragmatic’) in the PRECIS-2 summary wheel depicted here. The diverse primary care settings, mi

Updated on:May 06,2024 14

Incidence of dementia in primary care increased in the Netherlands over 23 years

by Public Library of ScienceCredit: CC0 Public DomainThe incidence of registered dementia cases has increased slightly over a 23-year period (1992 to 2014) in the Netherlands, according to a stud

Updated on: March 13,2024 19

Incidence of dementia in primary care increased in the Netherlands over 23 years

by Public Library of ScienceCredit: CC0 Public DomainThe incidence of registered dementia cases has increased slightly over a 23-year period (1992 to 2014) in the Netherlands, according to a stud

Updated on:March 13,2024 19

Long-term use of opioid patches common among persons with Alzheimer's disease

by University of Eastern FinlandApproximately seven per cent of persons with Alzheimer's disease use strong pain medicines, opioids, for non-cancer pain for a period longer than six months, a

Updated on: March 07,2024 16

Long-term use of opioid patches common among persons with Alzheimer's disease

by University of Eastern FinlandApproximately seven per cent of persons with Alzheimer's disease use strong pain medicines, opioids, for non-cancer pain for a period longer than six months, a

Updated on:March 07,2024 16

10 ways to reduce your risk of dementia

by Erin Fox,University of MichiganCredit: Pixabay/CC0 Public DomainDementia affects millions of Americans—includingnearly one in 10 adults over age 65. While the causes of different dement

Updated on: March 13,2024 12

10 ways to reduce your risk of dementia

by Erin Fox,University of MichiganCredit: Pixabay/CC0 Public DomainDementia affects millions of Americans—includingnearly one in 10 adults over age 65. While the causes of different dement

Updated on:March 13,2024 12

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on: March 02,2024 13

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on:March 02,2024 13

Study shows beneficial effects of blocking brain inflammation in experimental model of Alzheimer's

by University of SouthamptonDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A University of Southampton-led study has found that blocking a receptor

Updated on: February 27,2024 16

Study shows beneficial effects of blocking brain inflammation in experimental model of Alzheimer's

by University of SouthamptonDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A University of Southampton-led study has found that blocking a receptor

Updated on:February 27,2024 16

Biochemical clues may predict who develops Alzheimer's disease—and who doesn't

by ElsevierDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Investigators have wondered why the brains of some cognitively-intact elderly individuals

Updated on: February 27,2024 11

Biochemical clues may predict who develops Alzheimer's disease—and who doesn't

by ElsevierDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Investigators have wondered why the brains of some cognitively-intact elderly individuals

Updated on:February 27,2024 11

New memory drug moves into Phase 1 clinical study

by National Institutes of HealthAn experimental drug that may improve memory is now being tested in a Phase 1 safety trial. The compound, BPN14770, was developed by Tetra Discovery Partners, with

Updated on: February 27,2024 16

New memory drug moves into Phase 1 clinical study

by National Institutes of HealthAn experimental drug that may improve memory is now being tested in a Phase 1 safety trial. The compound, BPN14770, was developed by Tetra Discovery Partners, with

Updated on:February 27,2024 16

Estrogen may offer protection against delirium

by Cedars-Sinai Medical CenterOophorectomy (OVX) and urinary tract infection (UTI)-mediated changes in cleaved caspase-3 (CC3). (A) A schematic of design of a preliminary experiment examining the

Updated on: February 05,2024 15

Estrogen may offer protection against delirium

by Cedars-Sinai Medical CenterOophorectomy (OVX) and urinary tract infection (UTI)-mediated changes in cleaved caspase-3 (CC3). (A) A schematic of design of a preliminary experiment examining the

Updated on:February 05,2024 15

Assessment of balance deficits in neurocognitive disorders

by University of TsukubaCredit: Marta Wave from PexelsBalance is important to maintain in many aspects of life, but the most important may be your body's sense of balance—also known as vestib

Updated on: March 19,2024 19

Assessment of balance deficits in neurocognitive disorders

by University of TsukubaCredit: Marta Wave from PexelsBalance is important to maintain in many aspects of life, but the most important may be your body's sense of balance—also known as vestib

Updated on:March 19,2024 19