Silencing a faulty gene may uncover clues to rare forms of ALS

by National Institutes of HealthCredit: Pixabay/CC0 Public DomainUsing an experimental drug, researchers have been able to suppress a mutated amyotrophic lateral sclerosis (ALS) gene. Studies in

Updated on: February 05,2024

Silencing a faulty gene may uncover clues to rare forms of ALS

by National Institutes of HealthCredit: Pixabay/CC0 Public DomainUsing an experimental drug, researchers have been able to suppress a mutated amyotrophic lateral sclerosis (ALS) gene. Studies in

Updated on:February 05,2024

Cell-type-specific genetic risk contributes to distinct stages of Alzheimer's disease progression, finds study

by Brigham and Women's HospitalCell-type-specific Alzheimer’s disease polygenic risk scores (ADPRS).aA schematic of cell-type-specific PRS derivation.bAn UpSetR plot o

Updated on: February 24,2024

Cell-type-specific genetic risk contributes to distinct stages of Alzheimer's disease progression, finds study

by Brigham and Women's HospitalCell-type-specific Alzheimer’s disease polygenic risk scores (ADPRS).aA schematic of cell-type-specific PRS derivation.bAn UpSetR plot o

Updated on:February 24,2024

Scientists identify mutated gene behind mirror movement disorder

byUniversity of MontrealArhgef7 is required for Netrin-1–mediated commissural axon guidance. (A) The mean mRNA expression, fragments per kilobase of transcript per million mapped reads (fpkm), (

Updated on: April 22,2024

Scientists identify mutated gene behind mirror movement disorder

byUniversity of MontrealArhgef7 is required for Netrin-1–mediated commissural axon guidance. (A) The mean mRNA expression, fragments per kilobase of transcript per million mapped reads (fpkm), (

Updated on:April 22,2024

How SORLA protects against Alzheimer's disease

by Sanford-Burnham Prebys Medical Discovery InstituteHuaxi Xu, Ph.D., Professor, Neuroscience and Aging Research Center. Credit: Sanford Burnham Prebys Medical Discovery Institute (SBP)Researcher

Updated on: April 02,2024

How SORLA protects against Alzheimer's disease

by Sanford-Burnham Prebys Medical Discovery InstituteHuaxi Xu, Ph.D., Professor, Neuroscience and Aging Research Center. Credit: Sanford Burnham Prebys Medical Discovery Institute (SBP)Researcher

Updated on:April 02,2024

Down syndrome carries raised risk of dementia by 55

(HealthDay)—Most people with Down syndrome have dementia by age 55, a new study shows.People with Down syndrome are born with an extra copy of chromosome 21, which often results in developmental disab

Updated on: June 07,2024

Down syndrome carries raised risk of dementia by 55

(HealthDay)—Most people with Down syndrome have dementia by age 55, a new study shows.People with Down syndrome are born with an extra copy of chromosome 21, which often results in developmental disab

Updated on:June 07,2024

Scientists find a determining mechanism for synapse formation in the cerebellum

byMiguel Hernandez University of ElcheExpansion microscopy image with synaptic boutons (green) of climbing fibers on a Purkinje cell (blue) from the cerebellum of a mouse. Credit: CC BY IN-CSIC-

Updated on: July 11,2024

Scientists find a determining mechanism for synapse formation in the cerebellum

byMiguel Hernandez University of ElcheExpansion microscopy image with synaptic boutons (green) of climbing fibers on a Purkinje cell (blue) from the cerebellum of a mouse. Credit: CC BY IN-CSIC-

Updated on:July 11,2024

Can traditional chinese medicine offer treatments for dementia and Alzheimer's disease?

A new study of classical Chinese medical texts identifies references to age-related memory impairment similar to modern-day Alzheimer's disease, and to several plant-based ingredients used centuri

Updated on: March 07,2024

Can traditional chinese medicine offer treatments for dementia and Alzheimer's disease?

A new study of classical Chinese medical texts identifies references to age-related memory impairment similar to modern-day Alzheimer's disease, and to several plant-based ingredients used centuri

Updated on:March 07,2024

Clinical trial suggests ALS drug effective for treating spinal cord injuries

by Laurie Fickman,University of HoustonRiluzole trough and peak concentrations from Phase I and Phase II/III trials presented in waterfall plots. Credit:Journal of Neurotrauma(2023).

Updated on: January 11,2024

Clinical trial suggests ALS drug effective for treating spinal cord injuries

by Laurie Fickman,University of HoustonRiluzole trough and peak concentrations from Phase I and Phase II/III trials presented in waterfall plots. Credit:Journal of Neurotrauma(2023).

Updated on:January 11,2024

5 ways to lower your chances of getting Alzheimer's

by University of Southern CaliforniaCredit: University of Southern CaliforniaRetain a sharp, healthy brain and reduce your risk of Alzheimer's disease by following five simple rules. Some of

Updated on: June 24,2024

5 ways to lower your chances of getting Alzheimer's

by University of Southern CaliforniaCredit: University of Southern CaliforniaRetain a sharp, healthy brain and reduce your risk of Alzheimer's disease by following five simple rules. Some of

Updated on:June 24,2024

Scientists uncover new molecular drivers of Alzheimer's

by The Scripps Research InstituteA tiny glass tube (top left) represents the electrode recording from an excitatory human Alzheimer's neuron, generated using modern stem cell techniques (dark

Updated on: June 15,2024

Scientists uncover new molecular drivers of Alzheimer's

by The Scripps Research InstituteA tiny glass tube (top left) represents the electrode recording from an excitatory human Alzheimer's neuron, generated using modern stem cell techniques (dark

Updated on:June 15,2024

Family caregivers find support on #dementia TikTok

by Kate WellsCredit: Unsplash/CC0 Public DomainIt all changed on a Saturday night in New York City in 2016. Jacquelyn Revere was 29 and headed out to attend a friend's comedy show. She was on the

Updated on: June 20,2024

Family caregivers find support on #dementia TikTok

by Kate WellsCredit: Unsplash/CC0 Public DomainIt all changed on a Saturday night in New York City in 2016. Jacquelyn Revere was 29 and headed out to attend a friend's comedy show. She was on the

Updated on:June 20,2024

For Alzheimer's patients, a controversial drug brings hope

by Hannah Critchfield and Kirby WilsonCredit: Pixabay/CC0 Public DomainAt 53, Michele Hall was at the height of her legal career. She'd just sent her three kids to college. She had decades ahead w

Updated on: May 26,2024

For Alzheimer's patients, a controversial drug brings hope

by Hannah Critchfield and Kirby WilsonCredit: Pixabay/CC0 Public DomainAt 53, Michele Hall was at the height of her legal career. She'd just sent her three kids to college. She had decades ahead w

Updated on:May 26,2024