Sorting protein in neurons defends against neurodegenerative disease

by Temple UniversityDomenico Praticò, MD, Scott Richards North Star Foundation Chair for Alzheimer's Research, Professor in the Departments of Pharmacology and Microbiology, and Director of t

Updated on: May 26,2024

Sorting protein in neurons defends against neurodegenerative disease

by Temple UniversityDomenico Praticò, MD, Scott Richards North Star Foundation Chair for Alzheimer's Research, Professor in the Departments of Pharmacology and Microbiology, and Director of t

Updated on:May 26,2024

Alzheimer's disease could be treated with gene therapy, animal study suggests

by Imperial College LondonBrain cells from a mouse cortex that didn't receive the gene therapy. The amyloid plaques are shown in green, and the glial cells, which surround the plaques, are sh

Updated on: May 22,2024

Alzheimer's disease could be treated with gene therapy, animal study suggests

by Imperial College LondonBrain cells from a mouse cortex that didn't receive the gene therapy. The amyloid plaques are shown in green, and the glial cells, which surround the plaques, are sh

Updated on:May 22,2024

New insights into the development of Parkinson's disease in the brain might open the doors to new therapies

byTokyo Medical and Dental UniversityIn healthy condition, CHCHD2WT localizes in mitochondria. In pathogenic condition, mutant CHCHD2T61I mislocalizes to the cytosol and recruits Casein kinase 1

Updated on: March 14,2024

New insights into the development of Parkinson's disease in the brain might open the doors to new therapies

byTokyo Medical and Dental UniversityIn healthy condition, CHCHD2WT localizes in mitochondria. In pathogenic condition, mutant CHCHD2T61I mislocalizes to the cytosol and recruits Casein kinase 1

Updated on:March 14,2024

Good timing: Study unravels how our brains track time

by Keyonna Summers,University of Nevada, Las VegasA UNLV research team explored how the brain tells time. Credit: Talha K. Soluoku/UNLVEver hear the old adage that time flies when you're hav

Updated on: July 31,2024

Good timing: Study unravels how our brains track time

by Keyonna Summers,University of Nevada, Las VegasA UNLV research team explored how the brain tells time. Credit: Talha K. Soluoku/UNLVEver hear the old adage that time flies when you're hav

Updated on:July 31,2024

Controversial Alzheimer's drug should not be approved out of desperation, warn Aussie experts

by Medical Journal of AustraliaCredit: Unsplash/CC0 Public DomainAducanumab, a controversial Alzheimer's disease medication with "questionable efficacy," is under review by the Therapeut

Updated on: April 25,2024

Controversial Alzheimer's drug should not be approved out of desperation, warn Aussie experts

by Medical Journal of AustraliaCredit: Unsplash/CC0 Public DomainAducanumab, a controversial Alzheimer's disease medication with "questionable efficacy," is under review by the Therapeut

Updated on:April 25,2024

Living with Alzheimer's: China's health time bomb

Credit: CC0 Public DomainThe first time Chen Shaohua went missing and was picked up by police, the 68-year-old's family put it down to confusion.When he disappeared a second time, they realised he

Updated on: April 25,2024

Living with Alzheimer's: China's health time bomb

Credit: CC0 Public DomainThe first time Chen Shaohua went missing and was picked up by police, the 68-year-old's family put it down to confusion.When he disappeared a second time, they realised he

Updated on:April 25,2024

Alzheimer's research with primates could address treatments that show promise in mice but don't help humans

by Agnès Lacreuse, Allyson J. Bennett and Amanda M. Dettmer,The ConversationRhesus macaques experience an aging process similar to people’s. Credit: Unsplash/CC0 Public DomainAs of 2022, an esti

Updated on: May 26,2024

Alzheimer's research with primates could address treatments that show promise in mice but don't help humans

by Agnès Lacreuse, Allyson J. Bennett and Amanda M. Dettmer,The ConversationRhesus macaques experience an aging process similar to people’s. Credit: Unsplash/CC0 Public DomainAs of 2022, an esti

Updated on:May 26,2024

How our brains learn new athletic skills fast: Investigating electrocortical activity and faster locomotor adaptation

byUniversity of FloridaVisual Overview. Credit:eneuro(2024). DOI: 10.1523/ENEURO.0515-23.2024You join a swing dance class, and at first you're all left feet. But—slowly, eyes glu

Updated on: July 31,2024

How our brains learn new athletic skills fast: Investigating electrocortical activity and faster locomotor adaptation

byUniversity of FloridaVisual Overview. Credit:eneuro(2024). DOI: 10.1523/ENEURO.0515-23.2024You join a swing dance class, and at first you're all left feet. But—slowly, eyes glu

Updated on:July 31,2024

Is a commonly-used screening tool for cognitive impairment accurate in diverse populations?

by WileyCredit: Pixabay/CC0 Public DomainA screening tool often used in primary care clinics to detect cognitive impairment has shortcomings when applied to ethnically and linguistically diverse

Updated on: February 24,2024

Is a commonly-used screening tool for cognitive impairment accurate in diverse populations?

by WileyCredit: Pixabay/CC0 Public DomainA screening tool often used in primary care clinics to detect cognitive impairment has shortcomings when applied to ethnically and linguistically diverse

Updated on:February 24,2024

Clinical trial suggests ALS drug effective for treating spinal cord injuries

by Laurie Fickman,University of HoustonRiluzole trough and peak concentrations from Phase I and Phase II/III trials presented in waterfall plots. Credit:Journal of Neurotrauma(2023).

Updated on: January 11,2024

Clinical trial suggests ALS drug effective for treating spinal cord injuries

by Laurie Fickman,University of HoustonRiluzole trough and peak concentrations from Phase I and Phase II/III trials presented in waterfall plots. Credit:Journal of Neurotrauma(2023).

Updated on:January 11,2024

ALS and frontotemporal dementia show origins in utero, according to new study

by Cristy Lytal,Keck School of Medicine of USCGrpahical abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112983Even though neurodegenerative diseases often strike in m

Updated on: June 05,2024

ALS and frontotemporal dementia show origins in utero, according to new study

by Cristy Lytal,Keck School of Medicine of USCGrpahical abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112983Even though neurodegenerative diseases often strike in m

Updated on:June 05,2024

Overlooked brain organ plays key role in promoting brain repair after stroke, researchers discover

byUniversity of CincinnatiFluorescent image of a healthy choroid plexus, the main producer of cerebrospinal fluid in the brain. Credit: Agnes (Yu) LuoUniversity of Cincinnati researchers have pi

Updated on: July 08,2024

Overlooked brain organ plays key role in promoting brain repair after stroke, researchers discover

byUniversity of CincinnatiFluorescent image of a healthy choroid plexus, the main producer of cerebrospinal fluid in the brain. Credit: Agnes (Yu) LuoUniversity of Cincinnati researchers have pi

Updated on:July 08,2024