Aβ43 generation in familial Alzheimer's disease: New insights into disease onset

by Doshisha UniversityIn this study, γ-secretase was extracted from wild type (WT) cells and cells carrying FAD-related genetic mutations (mutations in presenilin 1: L85P, I143T, H163R, L166P, G206V,

Updated on: June 20,2024

Aβ43 generation in familial Alzheimer's disease: New insights into disease onset

by Doshisha UniversityIn this study, γ-secretase was extracted from wild type (WT) cells and cells carrying FAD-related genetic mutations (mutations in presenilin 1: L85P, I143T, H163R, L166P, G206V,

Updated on:June 20,2024

Scientists demonstrate how individual differences in 'whole-brain' activity are generated in roundworms

by University of TokyoA snapshot taken with a confocal microscope of the whole brain of a roundworm. Credit: Toyoshima et al 2024Joint research led by Yu Toyoshima and Yuichi Iino of the Universi

Updated on: March 19,2024

Scientists demonstrate how individual differences in 'whole-brain' activity are generated in roundworms

by University of TokyoA snapshot taken with a confocal microscope of the whole brain of a roundworm. Credit: Toyoshima et al 2024Joint research led by Yu Toyoshima and Yuichi Iino of the Universi

Updated on:March 19,2024

Abnormalities in genes linked to IRSP in Alzheimer's disease

(HealthDay)—Individuals with Alzheimer's disease (AD) have abnormalities and reductions in gene expression in the parahippocampal gyri that map to genes associated with the insulin receptor signal

Updated on: April 18,2024

Abnormalities in genes linked to IRSP in Alzheimer's disease

(HealthDay)—Individuals with Alzheimer's disease (AD) have abnormalities and reductions in gene expression in the parahippocampal gyri that map to genes associated with the insulin receptor signal

Updated on:April 18,2024

Blind people sense their heartbeats better than sighted people, shows study

by Anna Molin,Karolinska InstitutetA new study compared how well blind versus sighteed sensed their own heartbeats. Credit: Julia KorczykBlind people are better at sensing their own heartbeats t

Updated on: January 21,2024

Blind people sense their heartbeats better than sighted people, shows study

by Anna Molin,Karolinska InstitutetA new study compared how well blind versus sighteed sensed their own heartbeats. Credit: Julia KorczykBlind people are better at sensing their own heartbeats t

Updated on:January 21,2024

3D-printed acoustic holograms against Alzheimer's or Parkinson's

by Universitat Politècnica de València3D-printed acoustic hologram. Credit: Universitat Politècnica de ValènciaThe holograms designed by the team of researchers from UPV and CSIC allow the opening of

Updated on: January 21,2024

3D-printed acoustic holograms against Alzheimer's or Parkinson's

by Universitat Politècnica de València3D-printed acoustic hologram. Credit: Universitat Politècnica de ValènciaThe holograms designed by the team of researchers from UPV and CSIC allow the opening of

Updated on:January 21,2024

Gold nanoclusters: New frontier for developing medication for treatment of Alzheimer's disease

by Science China PressAu23(CR)14 Nanocluster functions in multiple stages of the progression from Aβ monomer to Aβ plaques. Credit: ©Science China PressAlzheimer's disease (AD) is a progressi

Updated on: July 01,2024

Gold nanoclusters: New frontier for developing medication for treatment of Alzheimer's disease

by Science China PressAu23(CR)14 Nanocluster functions in multiple stages of the progression from Aβ monomer to Aβ plaques. Credit: ©Science China PressAlzheimer's disease (AD) is a progressi

Updated on:July 01,2024

Studies identify novel underpinnings of genetic ALS

by Melissa Rohman,Northwestern UniversityLeft: Neuron at the motor cortex of a C9ORF72 patient stained for MAP2 and rRNA, showing the pattern of expression of ribosomal RNA in a human neuron mos

Updated on: January 10,2024

Studies identify novel underpinnings of genetic ALS

by Melissa Rohman,Northwestern UniversityLeft: Neuron at the motor cortex of a C9ORF72 patient stained for MAP2 and rRNA, showing the pattern of expression of ribosomal RNA in a human neuron mos

Updated on:January 10,2024

Study shows potential of optogenetics in treating epilepsy

byUniversity of California, San FranciscoHD-MEA recordings of human hippocampal slices. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024-01782-5In what could one day become

Updated on: November 22,2024

Study shows potential of optogenetics in treating epilepsy

byUniversity of California, San FranciscoHD-MEA recordings of human hippocampal slices. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024-01782-5In what could one day become

Updated on:November 22,2024

Chemical tool illuminates pathways used by dopamine, opioids and other neuronal signals

by Emily Kagey,University of MichiganA slice of the mouse brainstem demonstrates the detection of morphine (green) and the expression of the SPOTIT sensor (magenta). Credit: Noam Gannot and Peng

Updated on: April 28,2024

Chemical tool illuminates pathways used by dopamine, opioids and other neuronal signals

by Emily Kagey,University of MichiganA slice of the mouse brainstem demonstrates the detection of morphine (green) and the expression of the SPOTIT sensor (magenta). Credit: Noam Gannot and Peng

Updated on:April 28,2024

Neural prosthetic device can help humans restore memory

byAtrium Health Wake Forest BaptistDelayed match to sample (DMS) task performed on a touch screen by patients seated in either the hospital bed or a chair. Trial is started by patient touching a

Updated on: March 13,2024

Neural prosthetic device can help humans restore memory

byAtrium Health Wake Forest BaptistDelayed match to sample (DMS) task performed on a touch screen by patients seated in either the hospital bed or a chair. Trial is started by patient touching a

Updated on:March 13,2024

Study opens the door to earlier diagnosis and potential treatment for Alzheimer's disease

by Aarhus UniversityLarge Aβ Agg [+] MCI patients display lower AD-like brain pathology than large Aβ Agg [-] MCI.a18F-FTP PET uptake in each group at baseline, two-year follow-up, an

Updated on: March 19,2024

Study opens the door to earlier diagnosis and potential treatment for Alzheimer's disease

by Aarhus UniversityLarge Aβ Agg [+] MCI patients display lower AD-like brain pathology than large Aβ Agg [-] MCI.a18F-FTP PET uptake in each group at baseline, two-year follow-up, an

Updated on:March 19,2024

Risk factors of Alzheimer's disease and metabolic syndrome can accumulate in childhood

byUniversity of Eastern FinlandCredit: CC0 Public DomainGenetic predisposition to Alzheimer's disease is linked to an increased risk of cardiometabolic disorders present in childhood, a new

Updated on: April 08,2024

Risk factors of Alzheimer's disease and metabolic syndrome can accumulate in childhood

byUniversity of Eastern FinlandCredit: CC0 Public DomainGenetic predisposition to Alzheimer's disease is linked to an increased risk of cardiometabolic disorders present in childhood, a new

Updated on:April 08,2024