Researchers discover new molecular drug targets for progressive neurological disorder

by Lynda De Widt,Mayo ClinicSingle-nucleus RNAseq captures glial expression changes in PSP brains. a Nuclei in UMAP space colored by cluster number and grouped by its cell type. b Average expres

Updated on: January 10,2024 19

Researchers discover new molecular drug targets for progressive neurological disorder

by Lynda De Widt,Mayo ClinicSingle-nucleus RNAseq captures glial expression changes in PSP brains. a Nuclei in UMAP space colored by cluster number and grouped by its cell type. b Average expres

Updated on:January 10,2024 19

Cognitive impairment afflicts majority of stroke patients

by Wenche Margrethe Kulmo,Norwegian University of Science and TechnologyCredit: Marcus Aurelius from PexelsParalysis and difficulty speaking are well-known problems following a stroke. Establish

Updated on: February 18,2024 10

Cognitive impairment afflicts majority of stroke patients

by Wenche Margrethe Kulmo,Norwegian University of Science and TechnologyCredit: Marcus Aurelius from PexelsParalysis and difficulty speaking are well-known problems following a stroke. Establish

Updated on:February 18,2024 10

Moments of clarity in dementia patients at end of life: Glimmers of hope?

by University of MichiganCredit: CC0 Public DomainIt happens unexpectedly: a person long thought lost to the ravages of dementia, unable to recall the events of their lives or even recognize thos

Updated on: May 08,2024 6

Moments of clarity in dementia patients at end of life: Glimmers of hope?

by University of MichiganCredit: CC0 Public DomainIt happens unexpectedly: a person long thought lost to the ravages of dementia, unable to recall the events of their lives or even recognize thos

Updated on:May 08,2024 6

Depression best treated by nonpharmacological approaches in people living with dementia

by University of New South WalesCredit: Pixabay/CC0 Public DomainResearch led by UNSW Sydney's Center for Healthy Brain Aging (CHeBA) has confirmed treating symptoms of depression is most eff

Updated on: May 06,2024 16

Depression best treated by nonpharmacological approaches in people living with dementia

by University of New South WalesCredit: Pixabay/CC0 Public DomainResearch led by UNSW Sydney's Center for Healthy Brain Aging (CHeBA) has confirmed treating symptoms of depression is most eff

Updated on:May 06,2024 16

Clinical trial finds herbal medicine Sailuotong effective for brain health in older people

by Western Sydney UniversityCredit: Pixabay/CC0 Public DomainWestern Sydney University's NICM Health Research Institute has led a world-first clinical trial in Australia that offers new hope

Updated on: March 02,2024 13

Clinical trial finds herbal medicine Sailuotong effective for brain health in older people

by Western Sydney UniversityCredit: Pixabay/CC0 Public DomainWestern Sydney University's NICM Health Research Institute has led a world-first clinical trial in Australia that offers new hope

Updated on:March 02,2024 13

Beyond neurons: How cells called astrocytes contribute to brain disorders

by Salk InstituteSalk researchers studied the molecules produced by astrocytes, like those pictured, to understand how the cells play a role in neurodevelopmental disorders. Credit: Salk Institut

Updated on: February 03,2024 17

Beyond neurons: How cells called astrocytes contribute to brain disorders

by Salk InstituteSalk researchers studied the molecules produced by astrocytes, like those pictured, to understand how the cells play a role in neurodevelopmental disorders. Credit: Salk Institut

Updated on:February 03,2024 17

Hippocampal study unveils distinct protein machineries for calcium channel clustering and vesicle priming

by Ingrid Fadelli , Medical XpressMunc13-1 and CaV2.1 nanoclustering. a–c, Example STED images of sideview synapses (a), quantification of line profiles (b) and Pearson's colocalization coefficien

Updated on: September 23,2024 0

Hippocampal study unveils distinct protein machineries for calcium channel clustering and vesicle priming

by Ingrid Fadelli , Medical XpressMunc13-1 and CaV2.1 nanoclustering. a–c, Example STED images of sideview synapses (a), quantification of line profiles (b) and Pearson's colocalization coefficien

Updated on:September 23,2024 0

High-energy lasers could be used to treat Alzheimer's disease in the future

by Tokyo University of ScienceCredit: CC0 Public DomainAmyloid fibrils are a type of self-assembled proteins/peptides that take on a stacked sheet-like formation. Amyloid fibril aggregates are kn

Updated on: June 04,2024 7

High-energy lasers could be used to treat Alzheimer's disease in the future

by Tokyo University of ScienceCredit: CC0 Public DomainAmyloid fibrils are a type of self-assembled proteins/peptides that take on a stacked sheet-like formation. Amyloid fibril aggregates are kn

Updated on:June 04,2024 7

Study reveals that the brain's cerebellum can shape cognition

by University of PittsburghThe cerebellum, which controls movement, balance and coordination, also plays a key role in reward-based learning, according to scientists at Pitt and Columbia Universi

Updated on: April 06,2024 0

Study reveals that the brain's cerebellum can shape cognition

by University of PittsburghThe cerebellum, which controls movement, balance and coordination, also plays a key role in reward-based learning, according to scientists at Pitt and Columbia Universi

Updated on:April 06,2024 0

Study reveals insights into link between genetic mutation and Parkinson's

by Bill Hathaway,Yale UniversityLRRK2 inhibits lysosomal protease activity in human iPSC-derived macrophages. (A) Airyscan live cell confocal micrographs showing lysosome labeling in human iPSC-

Updated on: April 26,2024 0

Study reveals insights into link between genetic mutation and Parkinson's

by Bill Hathaway,Yale UniversityLRRK2 inhibits lysosomal protease activity in human iPSC-derived macrophages. (A) Airyscan live cell confocal micrographs showing lysosome labeling in human iPSC-

Updated on:April 26,2024 0

Synthetic peptide can inhibit toxicity, aggregation of protein in Alzheimer's disease

by University of WashingtonPET scan of a human brain with Alzheimer's disease. Credit: public domainAlzheimer's is a disease of aggregation. Neurons in the human brain make a protein call

Updated on: June 07,2024 5

Synthetic peptide can inhibit toxicity, aggregation of protein in Alzheimer's disease

by University of WashingtonPET scan of a human brain with Alzheimer's disease. Credit: public domainAlzheimer's is a disease of aggregation. Neurons in the human brain make a protein call

Updated on:June 07,2024 5

Researchers make key improvements to Parkinson's disease cell therapies

JULY 13, 2023byMass General BrighamCredit: Pixabay/CC0 Public DomainCell therapy holds promise as a new treatment for Parkinson's disease but, in many trials to date, most transplanted dopam

Updated on: March 28,2024 2

Researchers make key improvements to Parkinson's disease cell therapies

JULY 13, 2023byMass General BrighamCredit: Pixabay/CC0 Public DomainCell therapy holds promise as a new treatment for Parkinson's disease but, in many trials to date, most transplanted dopam

Updated on:March 28,2024 2