Breakthrough research reveals a new target for Alzheimer's disease treatment

by VIB (the Flanders Institute for Biotechnology)A 3D visualization of lectin-stained blood vessels (magenta) and Thioflavin-S–positive (yellow) amyloid plaques in the brain of a mouse model of A

Updated on: February 26,2024

Breakthrough research reveals a new target for Alzheimer's disease treatment

by VIB (the Flanders Institute for Biotechnology)A 3D visualization of lectin-stained blood vessels (magenta) and Thioflavin-S–positive (yellow) amyloid plaques in the brain of a mouse model of A

Updated on:February 26,2024

Abnormalities in genes linked to IRSP in Alzheimer's disease

(HealthDay)—Individuals with Alzheimer's disease (AD) have abnormalities and reductions in gene expression in the parahippocampal gyri that map to genes associated with the insulin receptor signal

Updated on: April 18,2024

Abnormalities in genes linked to IRSP in Alzheimer's disease

(HealthDay)—Individuals with Alzheimer's disease (AD) have abnormalities and reductions in gene expression in the parahippocampal gyri that map to genes associated with the insulin receptor signal

Updated on:April 18,2024

Researchers detail mechanism of a key protein implicated in age-related brain dysfunction

byThe Mount Sinai HospitalAccumulation of extracellular matrix content in brain of TIMP2-deficient "KO" mice (left column) that leads to impaired plasticity processes, including the mi

Updated on: January 10,2024

Researchers detail mechanism of a key protein implicated in age-related brain dysfunction

byThe Mount Sinai HospitalAccumulation of extracellular matrix content in brain of TIMP2-deficient "KO" mice (left column) that leads to impaired plasticity processes, including the mi

Updated on:January 10,2024

Comorbidities can increase plasma biomarker levels associated with Alzheimer's disease

by Wake Forest University Baptist Medical CenterCredit: Pixabay/CC0 Public DomainA simple blood test to diagnose Alzheimer's disease, perhaps even years before symptoms appear, is an exciting

Updated on: June 07,2024

Comorbidities can increase plasma biomarker levels associated with Alzheimer's disease

by Wake Forest University Baptist Medical CenterCredit: Pixabay/CC0 Public DomainA simple blood test to diagnose Alzheimer's disease, perhaps even years before symptoms appear, is an exciting

Updated on:June 07,2024

'Viral relicts' in the genome could fuel neurodegeneration

by Marcus Neitzert, Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)Different HERV glycoproteins increase intercellular protein aggregate spreading.aExperimental workflow.

Updated on: June 18,2024

'Viral relicts' in the genome could fuel neurodegeneration

by Marcus Neitzert, Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)Different HERV glycoproteins increase intercellular protein aggregate spreading.aExperimental workflow.

Updated on:June 18,2024

Study reveals insights into link between genetic mutation and Parkinson's

by Bill Hathaway,Yale UniversityLRRK2 inhibits lysosomal protease activity in human iPSC-derived macrophages. (A) Airyscan live cell confocal micrographs showing lysosome labeling in human iPSC-

Updated on: April 26,2024

Study reveals insights into link between genetic mutation and Parkinson's

by Bill Hathaway,Yale UniversityLRRK2 inhibits lysosomal protease activity in human iPSC-derived macrophages. (A) Airyscan live cell confocal micrographs showing lysosome labeling in human iPSC-

Updated on:April 26,2024

How being friends with someone who has dementia can be good for you both

by Janelle Taylor,The ConversationCredit: AI-generated imageEach year, in the final few hours of the last day of December, many people all across North America gather with friends to raise a gla

Updated on: June 07,2024

How being friends with someone who has dementia can be good for you both

by Janelle Taylor,The ConversationCredit: AI-generated imageEach year, in the final few hours of the last day of December, many people all across North America gather with friends to raise a gla

Updated on:June 07,2024

Retraining the brain for better vision

by Eric Bender,Massachusetts Institute of TechnologyProfessor Mark Bear. Credit: David Sella/MIT Corporate RelationsHundreds of millions of people worldwide suffer from a vision condition called

Updated on: January 12,2024

Retraining the brain for better vision

by Eric Bender,Massachusetts Institute of TechnologyProfessor Mark Bear. Credit: David Sella/MIT Corporate RelationsHundreds of millions of people worldwide suffer from a vision condition called

Updated on:January 12,2024

How heavy alcohol consumption increases brain inflammation

by The Scripps Research InstituteResearchers discovered higher than usual levels of the immune signaling molecule interleukin 1β (green) in neurons (outlined in red) from the brains of alcohol-de

Updated on: February 18,2024

How heavy alcohol consumption increases brain inflammation

by The Scripps Research InstituteResearchers discovered higher than usual levels of the immune signaling molecule interleukin 1β (green) in neurons (outlined in red) from the brains of alcohol-de

Updated on:February 18,2024

Older people with early, asymptomatic Alzheimer's at risk of falls

by Tamara Bhandari,Washington University School of MedicineCredit: CC0 Public DomainFalls are the leading cause of fatal injuries in older adults, causing more than 800,000 hospitalizations and

Updated on: June 11,2024

Older people with early, asymptomatic Alzheimer's at risk of falls

by Tamara Bhandari,Washington University School of MedicineCredit: CC0 Public DomainFalls are the leading cause of fatal injuries in older adults, causing more than 800,000 hospitalizations and

Updated on:June 11,2024

Too few seniors are getting their memory tested

by Serena Gordon, Healthday Reporter(HealthDay)—Most seniors expect their doctor to recommend testing of thinking and memory when it's needed.But a new survey discovered that is rarely the case: O

Updated on: June 07,2024

Too few seniors are getting their memory tested

by Serena Gordon, Healthday Reporter(HealthDay)—Most seniors expect their doctor to recommend testing of thinking and memory when it's needed.But a new survey discovered that is rarely the case: O

Updated on:June 07,2024

Post-COVID condition is not linked to ongoing infection or active brain damage, study shows

by Gustav Löfgren,Swedish Research CouncilPrincipal component analysis plot of 5 neurobiomarkers in CSF. The centroids for each group are indicated and surrounded with ellipses indicating 95% co

Updated on: January 11,2024

Post-COVID condition is not linked to ongoing infection or active brain damage, study shows

by Gustav Löfgren,Swedish Research CouncilPrincipal component analysis plot of 5 neurobiomarkers in CSF. The centroids for each group are indicated and surrounded with ellipses indicating 95% co

Updated on:January 11,2024