Molecular clusters on glial cells show they are more than our brain's 'glue'

FEBRUARY 28, 2024byFred Hutchinson Cancer CenterGraphical abstract. Credit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113844Neuroscientists at Fred Hutchinson Cancer Center have

Updated on: March 25,2024 11

Molecular clusters on glial cells show they are more than our brain's 'glue'

FEBRUARY 28, 2024byFred Hutchinson Cancer CenterGraphical abstract. Credit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113844Neuroscientists at Fred Hutchinson Cancer Center have

Updated on:March 25,2024 11

Novel Rett syndrome variant shines light on new screening strategies for therapies

byTexas Children's HospitalMeCP2 protein level is reduced in the patient fibroblast-derived neurons. (A) Diagram of MeCP2 protein with the G118E mutation in the methyl-CpG binding domain (MB

Updated on: January 11,2024 10

Novel Rett syndrome variant shines light on new screening strategies for therapies

byTexas Children's HospitalMeCP2 protein level is reduced in the patient fibroblast-derived neurons. (A) Diagram of MeCP2 protein with the G118E mutation in the methyl-CpG binding domain (MB

Updated on:January 11,2024 10

Freedom, dignity in French Alzheimer's 'village'

Credit: Pixabay/CC0 Public DomainThe small village, like most in France, has a cafe-restaurant, a hairdresser, a superette and a library.Neighbours have a cup of coffee and a chat on the terrace, or m

Updated on: June 01,2024 5

Freedom, dignity in French Alzheimer's 'village'

Credit: Pixabay/CC0 Public DomainThe small village, like most in France, has a cafe-restaurant, a hairdresser, a superette and a library.Neighbours have a cup of coffee and a chat on the terrace, or m

Updated on:June 01,2024 5

Alzheimer's treatment holds promise for primary progressive aphasia patients

by Northwestern UniversityCredit: CC0 Public DomainNorthwestern Medicine scientists have discovered that an existing therapy frequently used to treat Alzheimer's disease might also work on pa

Updated on: April 08,2024 10

Alzheimer's treatment holds promise for primary progressive aphasia patients

by Northwestern UniversityCredit: CC0 Public DomainNorthwestern Medicine scientists have discovered that an existing therapy frequently used to treat Alzheimer's disease might also work on pa

Updated on:April 08,2024 10

Restoring 'chaperone' protein may prevent plaque build-up in Alzheimer's

by Perelman School of Medicine at the University of PennsylvaniaDAXX (red color at top) prevents the aggregation of mutant p53 protein associated with cancers (dark green color at bottom) in cell

Updated on: June 11,2024 7

Restoring 'chaperone' protein may prevent plaque build-up in Alzheimer's

by Perelman School of Medicine at the University of PennsylvaniaDAXX (red color at top) prevents the aggregation of mutant p53 protein associated with cancers (dark green color at bottom) in cell

Updated on:June 11,2024 7

Early diagnosis of Alzheimer's: Ultra-long protein fibrils give clues on dementia risk

by Swiss Federal Laboratories for Materials Science and TechnologyAtomic force microscopy: Peter Nirmalraj investigates Alzheimer's disease at the nanometer scale. Credit: EmpaThe early detec

Updated on: April 18,2024 19

Early diagnosis of Alzheimer's: Ultra-long protein fibrils give clues on dementia risk

by Swiss Federal Laboratories for Materials Science and TechnologyAtomic force microscopy: Peter Nirmalraj investigates Alzheimer's disease at the nanometer scale. Credit: EmpaThe early detec

Updated on:April 18,2024 19

Researchers find connections between neuroinflammation and Alzheimer's disease

by Brigham and Women's HospitalINPP5D expression in the human brain is restricted to microglia in the human brain. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-4281

Updated on: June 19,2024 3

Researchers find connections between neuroinflammation and Alzheimer's disease

by Brigham and Women's HospitalINPP5D expression in the human brain is restricted to microglia in the human brain. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-4281

Updated on:June 19,2024 3

A new treatment reduces inflammation in multiple sclerosis mice models

by Autonomous University of BarcelonaMaR1 reduces pro-inflammatory cytokines in the spinal cord of EAE mice. Plot showing the fold change in cytokine protein levels of different cytokines in the

Updated on: March 25,2024 18

A new treatment reduces inflammation in multiple sclerosis mice models

by Autonomous University of BarcelonaMaR1 reduces pro-inflammatory cytokines in the spinal cord of EAE mice. Plot showing the fold change in cytokine protein levels of different cytokines in the

Updated on:March 25,2024 18

Improving quality of life and sleep in people with memory problems without using drugs

by University of Pennsylvania School of NursingCredit: Pixabay/CC0 Public DomainA study from the University of Pennsylvania School of Nursing (Penn Nursing), recentlypublishedin

Updated on: March 05,2024 17

Improving quality of life and sleep in people with memory problems without using drugs

by University of Pennsylvania School of NursingCredit: Pixabay/CC0 Public DomainA study from the University of Pennsylvania School of Nursing (Penn Nursing), recentlypublishedin

Updated on:March 05,2024 17

Experiments on mice reveal the parts of the brain involved in motion sickness

by Bob Yirka , Medical XpressIdentification of glutamatergic neuronal subpopulations in the VN. (A)Slc17a6Cremice were bilaterally injected in the VN with a viral vector expressing the Rib

Updated on: January 11,2024 10

Experiments on mice reveal the parts of the brain involved in motion sickness

by Bob Yirka , Medical XpressIdentification of glutamatergic neuronal subpopulations in the VN. (A)Slc17a6Cremice were bilaterally injected in the VN with a viral vector expressing the Rib

Updated on:January 11,2024 10

Global dementia cases set to triple by 2050 unless countries address risk factors

by LancetCredit: Pixabay/CC0 Public DomainThe number of adults (aged 40 years and older) living with dementia worldwide is expected to nearly triple, from an estimated 57 million in 2019 to 153 m

Updated on: May 13,2024 5

Global dementia cases set to triple by 2050 unless countries address risk factors

by LancetCredit: Pixabay/CC0 Public DomainThe number of adults (aged 40 years and older) living with dementia worldwide is expected to nearly triple, from an estimated 57 million in 2019 to 153 m

Updated on:May 13,2024 5

Alzheimer's disease risk gene APOE4 impairs function of brain immune cells

by University of Eastern FinlandThe induced pluripotent stem cell (iPSC) -derived microglia demonstrate that apolipoprotein E4 (APOE4) has a profound impact on several functions of human brain im

Updated on: April 08,2024 18

Alzheimer's disease risk gene APOE4 impairs function of brain immune cells

by University of Eastern FinlandThe induced pluripotent stem cell (iPSC) -derived microglia demonstrate that apolipoprotein E4 (APOE4) has a profound impact on several functions of human brain im

Updated on:April 08,2024 18