Gene-editing tools pave way for new Alzheimer's treatments

by Cara MurezTwo new studies using CRISPR gene editing offer potential new treatments for Alzheimer's disease."A pipeline of potential new treatments offers hope for the Alzheimer's and d

Updated on: June 14,2024

Gene-editing tools pave way for new Alzheimer's treatments

by Cara MurezTwo new studies using CRISPR gene editing offer potential new treatments for Alzheimer's disease."A pipeline of potential new treatments offers hope for the Alzheimer's and d

Updated on:June 14,2024

Most COVID-19 'long haulers' continue to experience symptoms 15 months after initial infection

by Northwestern UniversityPROMIS Quality of Life domain scores for cognitive function and fatigue, by SARS-CoV-2 result. (A) T-scores from the first clinic visit (circles) and follow-up (triangle

Updated on: February 18,2024

Most COVID-19 'long haulers' continue to experience symptoms 15 months after initial infection

by Northwestern UniversityPROMIS Quality of Life domain scores for cognitive function and fatigue, by SARS-CoV-2 result. (A) T-scores from the first clinic visit (circles) and follow-up (triangle

Updated on:February 18,2024

Breakthrough research reveals a new target for Alzheimer's disease treatment

by VIB (the Flanders Institute for Biotechnology)A 3D visualization of lectin-stained blood vessels (magenta) and Thioflavin-S–positive (yellow) amyloid plaques in the brain of a mouse model of A

Updated on: February 26,2024

Breakthrough research reveals a new target for Alzheimer's disease treatment

by VIB (the Flanders Institute for Biotechnology)A 3D visualization of lectin-stained blood vessels (magenta) and Thioflavin-S–positive (yellow) amyloid plaques in the brain of a mouse model of A

Updated on:February 26,2024

Researchers detail mechanism of a key protein implicated in age-related brain dysfunction

byThe Mount Sinai HospitalAccumulation of extracellular matrix content in brain of TIMP2-deficient "KO" mice (left column) that leads to impaired plasticity processes, including the mi

Updated on: January 10,2024

Researchers detail mechanism of a key protein implicated in age-related brain dysfunction

byThe Mount Sinai HospitalAccumulation of extracellular matrix content in brain of TIMP2-deficient "KO" mice (left column) that leads to impaired plasticity processes, including the mi

Updated on:January 10,2024

How being friends with someone who has dementia can be good for you both

by Janelle Taylor,The ConversationCredit: AI-generated imageEach year, in the final few hours of the last day of December, many people all across North America gather with friends to raise a gla

Updated on: June 07,2024

How being friends with someone who has dementia can be good for you both

by Janelle Taylor,The ConversationCredit: AI-generated imageEach year, in the final few hours of the last day of December, many people all across North America gather with friends to raise a gla

Updated on:June 07,2024

Study opens the door to earlier diagnosis and potential treatment for Alzheimer's disease

by Aarhus UniversityLarge Aβ Agg [+] MCI patients display lower AD-like brain pathology than large Aβ Agg [-] MCI.a18F-FTP PET uptake in each group at baseline, two-year follow-up, an

Updated on: March 19,2024

Study opens the door to earlier diagnosis and potential treatment for Alzheimer's disease

by Aarhus UniversityLarge Aβ Agg [+] MCI patients display lower AD-like brain pathology than large Aβ Agg [-] MCI.a18F-FTP PET uptake in each group at baseline, two-year follow-up, an

Updated on:March 19,2024

'Viral relicts' in the genome could fuel neurodegeneration

by Marcus Neitzert, Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)Different HERV glycoproteins increase intercellular protein aggregate spreading.aExperimental workflow.

Updated on: June 18,2024

'Viral relicts' in the genome could fuel neurodegeneration

by Marcus Neitzert, Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)Different HERV glycoproteins increase intercellular protein aggregate spreading.aExperimental workflow.

Updated on:June 18,2024

Post-COVID condition is not linked to ongoing infection or active brain damage, study shows

by Gustav Löfgren,Swedish Research CouncilPrincipal component analysis plot of 5 neurobiomarkers in CSF. The centroids for each group are indicated and surrounded with ellipses indicating 95% co

Updated on: January 11,2024

Post-COVID condition is not linked to ongoing infection or active brain damage, study shows

by Gustav Löfgren,Swedish Research CouncilPrincipal component analysis plot of 5 neurobiomarkers in CSF. The centroids for each group are indicated and surrounded with ellipses indicating 95% co

Updated on:January 11,2024

Lockdown and dementia: For some, COVID-19 has created an isolated, confusing but calmer world

by Catherine Talbot,The ConversationCredit: AI-generated imageThe approximately850,000people living with dementia in the UK have been badly affected by COVID-19. Many live in care ho

Updated on: June 01,2024

Lockdown and dementia: For some, COVID-19 has created an isolated, confusing but calmer world

by Catherine Talbot,The ConversationCredit: AI-generated imageThe approximately850,000people living with dementia in the UK have been badly affected by COVID-19. Many live in care ho

Updated on:June 01,2024

Women with a heart healthy diet in midlife are less likely to report cognitive decline later: Study

by NYU Langone HealthCredit: Pixabay/CC0 Public DomainWomen with diets during middle age designed to lower blood pressure were about 17% less likely to report memory loss and other signs of cogni

Updated on: February 24,2024

Women with a heart healthy diet in midlife are less likely to report cognitive decline later: Study

by NYU Langone HealthCredit: Pixabay/CC0 Public DomainWomen with diets during middle age designed to lower blood pressure were about 17% less likely to report memory loss and other signs of cogni

Updated on:February 24,2024

Older people with early, asymptomatic Alzheimer's at risk of falls

by Tamara Bhandari,Washington University School of MedicineCredit: CC0 Public DomainFalls are the leading cause of fatal injuries in older adults, causing more than 800,000 hospitalizations and

Updated on: June 11,2024

Older people with early, asymptomatic Alzheimer's at risk of falls

by Tamara Bhandari,Washington University School of MedicineCredit: CC0 Public DomainFalls are the leading cause of fatal injuries in older adults, causing more than 800,000 hospitalizations and

Updated on:June 11,2024

Study reveals insights into link between genetic mutation and Parkinson's

by Bill Hathaway,Yale UniversityLRRK2 inhibits lysosomal protease activity in human iPSC-derived macrophages. (A) Airyscan live cell confocal micrographs showing lysosome labeling in human iPSC-

Updated on: April 26,2024

Study reveals insights into link between genetic mutation and Parkinson's

by Bill Hathaway,Yale UniversityLRRK2 inhibits lysosomal protease activity in human iPSC-derived macrophages. (A) Airyscan live cell confocal micrographs showing lysosome labeling in human iPSC-

Updated on:April 26,2024