Gene-editing tools pave way for new Alzheimer's treatments

by Cara MurezTwo new studies using CRISPR gene editing offer potential new treatments for Alzheimer's disease."A pipeline of potential new treatments offers hope for the Alzheimer's and d

Updated on: June 14,2024

Gene-editing tools pave way for new Alzheimer's treatments

by Cara MurezTwo new studies using CRISPR gene editing offer potential new treatments for Alzheimer's disease."A pipeline of potential new treatments offers hope for the Alzheimer's and d

Updated on:June 14,2024

'Aggressive' new advance directive would let dementia patients refuse food

by Jonel Aleccia, Kaiser Health NewsCredit: CC0 Public DomainTreading into ethically and legally uncertain territory, a New York end-of-life agency has approved a new document that lets people stipula

Updated on: June 18,2024

'Aggressive' new advance directive would let dementia patients refuse food

by Jonel Aleccia, Kaiser Health NewsCredit: CC0 Public DomainTreading into ethically and legally uncertain territory, a New York end-of-life agency has approved a new document that lets people stipula

Updated on:June 18,2024

Epigenetic 'age' predicts cognitive function

by Will Doss,Northwestern UniversityCredit: Unsplash/CC0 Public DomainEpigenetic markers of cognitive aging can predict performance on cognitive tests later in life, according to a study publish

Updated on: April 29,2024

Epigenetic 'age' predicts cognitive function

by Will Doss,Northwestern UniversityCredit: Unsplash/CC0 Public DomainEpigenetic markers of cognitive aging can predict performance on cognitive tests later in life, according to a study publish

Updated on:April 29,2024

'Viral relicts' in the genome could fuel neurodegeneration

by Marcus Neitzert, Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)Different HERV glycoproteins increase intercellular protein aggregate spreading.aExperimental workflow.

Updated on: June 18,2024

'Viral relicts' in the genome could fuel neurodegeneration

by Marcus Neitzert, Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)Different HERV glycoproteins increase intercellular protein aggregate spreading.aExperimental workflow.

Updated on:June 18,2024

Researchers detail mechanism of a key protein implicated in age-related brain dysfunction

byThe Mount Sinai HospitalAccumulation of extracellular matrix content in brain of TIMP2-deficient "KO" mice (left column) that leads to impaired plasticity processes, including the mi

Updated on: January 10,2024

Researchers detail mechanism of a key protein implicated in age-related brain dysfunction

byThe Mount Sinai HospitalAccumulation of extracellular matrix content in brain of TIMP2-deficient "KO" mice (left column) that leads to impaired plasticity processes, including the mi

Updated on:January 10,2024

Study reveals insights into link between genetic mutation and Parkinson's

by Bill Hathaway,Yale UniversityLRRK2 inhibits lysosomal protease activity in human iPSC-derived macrophages. (A) Airyscan live cell confocal micrographs showing lysosome labeling in human iPSC-

Updated on: April 26,2024

Study reveals insights into link between genetic mutation and Parkinson's

by Bill Hathaway,Yale UniversityLRRK2 inhibits lysosomal protease activity in human iPSC-derived macrophages. (A) Airyscan live cell confocal micrographs showing lysosome labeling in human iPSC-

Updated on:April 26,2024

How being friends with someone who has dementia can be good for you both

by Janelle Taylor,The ConversationCredit: AI-generated imageEach year, in the final few hours of the last day of December, many people all across North America gather with friends to raise a gla

Updated on: June 07,2024

How being friends with someone who has dementia can be good for you both

by Janelle Taylor,The ConversationCredit: AI-generated imageEach year, in the final few hours of the last day of December, many people all across North America gather with friends to raise a gla

Updated on:June 07,2024

ALS and frontotemporal dementia show origins in utero, according to new study

by Cristy Lytal,Keck School of Medicine of USCGrpahical abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112983Even though neurodegenerative diseases often strike in m

Updated on: June 05,2024

ALS and frontotemporal dementia show origins in utero, according to new study

by Cristy Lytal,Keck School of Medicine of USCGrpahical abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112983Even though neurodegenerative diseases often strike in m

Updated on:June 05,2024

Tauvid receives approval for tau pathology imaging

(HealthDay)—Tauvid (flortaucipir F18), a radioactive diagnostic agent, was approved to image tau pathology in patients with cognitive impairment being evaluated for Alzheimer disease, the U.S. Food an

Updated on: April 02,2024

Tauvid receives approval for tau pathology imaging

(HealthDay)—Tauvid (flortaucipir F18), a radioactive diagnostic agent, was approved to image tau pathology in patients with cognitive impairment being evaluated for Alzheimer disease, the U.S. Food an

Updated on:April 02,2024

New cellular mechanisms in Parkinson's disease discovered

by Melissa Rohman,Northwestern UniversityCredit:Neuron(2024). DOI: 10.1016/j.neuron.2024.05.003A pair of recent studies led by Joseph Mazzulli, Ph.D., associate professor in The Ken

Updated on: July 08,2024

New cellular mechanisms in Parkinson's disease discovered

by Melissa Rohman,Northwestern UniversityCredit:Neuron(2024). DOI: 10.1016/j.neuron.2024.05.003A pair of recent studies led by Joseph Mazzulli, Ph.D., associate professor in The Ken

Updated on:July 08,2024

Too few seniors are getting their memory tested

by Serena Gordon, Healthday Reporter(HealthDay)—Most seniors expect their doctor to recommend testing of thinking and memory when it's needed.But a new survey discovered that is rarely the case: O

Updated on: June 07,2024

Too few seniors are getting their memory tested

by Serena Gordon, Healthday Reporter(HealthDay)—Most seniors expect their doctor to recommend testing of thinking and memory when it's needed.But a new survey discovered that is rarely the case: O

Updated on:June 07,2024

Sorting protein in neurons defends against neurodegenerative disease

by Temple UniversityDomenico Praticò, MD, Scott Richards North Star Foundation Chair for Alzheimer's Research, Professor in the Departments of Pharmacology and Microbiology, and Director of t

Updated on: May 26,2024

Sorting protein in neurons defends against neurodegenerative disease

by Temple UniversityDomenico Praticò, MD, Scott Richards North Star Foundation Chair for Alzheimer's Research, Professor in the Departments of Pharmacology and Microbiology, and Director of t

Updated on:May 26,2024