ALS and frontotemporal dementia show origins in utero, according to new study

by Cristy Lytal,Keck School of Medicine of USCGrpahical abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112983Even though neurodegenerative diseases often strike in m

Updated on: June 05,2024

ALS and frontotemporal dementia show origins in utero, according to new study

by Cristy Lytal,Keck School of Medicine of USCGrpahical abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112983Even though neurodegenerative diseases often strike in m

Updated on:June 05,2024

Single-cell dissection of Alzheimer's vascular changes across six brain regions

by Rachel Gordon, MIT Computer Science & Artificial Intelligence LabExperimental validation of adDEGs. a. Chromogenic RNAscope for ABCC9 and SLC6A1. Prefrontal cortex brain sections (n = 4 for AD

Updated on: April 20,2024

Single-cell dissection of Alzheimer's vascular changes across six brain regions

by Rachel Gordon, MIT Computer Science & Artificial Intelligence LabExperimental validation of adDEGs. a. Chromogenic RNAscope for ABCC9 and SLC6A1. Prefrontal cortex brain sections (n = 4 for AD

Updated on:April 20,2024

Majority of stroke patients with depression do not receive mental health treatment

byRegenstrief InstituteCredit: CC0 Public DomainAbout one in three stroke survivors will experience depression in the first year after a stroke. A new study from Regenstrief Institute, Indiana U

Updated on: February 18,2024

Majority of stroke patients with depression do not receive mental health treatment

byRegenstrief InstituteCredit: CC0 Public DomainAbout one in three stroke survivors will experience depression in the first year after a stroke. A new study from Regenstrief Institute, Indiana U

Updated on:February 18,2024

'Aggressive' new advance directive would let dementia patients refuse food

by Jonel Aleccia, Kaiser Health NewsCredit: CC0 Public DomainTreading into ethically and legally uncertain territory, a New York end-of-life agency has approved a new document that lets people stipula

Updated on: June 18,2024

'Aggressive' new advance directive would let dementia patients refuse food

by Jonel Aleccia, Kaiser Health NewsCredit: CC0 Public DomainTreading into ethically and legally uncertain territory, a New York end-of-life agency has approved a new document that lets people stipula

Updated on:June 18,2024

Study reveals insights into link between genetic mutation and Parkinson's

by Bill Hathaway,Yale UniversityLRRK2 inhibits lysosomal protease activity in human iPSC-derived macrophages. (A) Airyscan live cell confocal micrographs showing lysosome labeling in human iPSC-

Updated on: April 26,2024

Study reveals insights into link between genetic mutation and Parkinson's

by Bill Hathaway,Yale UniversityLRRK2 inhibits lysosomal protease activity in human iPSC-derived macrophages. (A) Airyscan live cell confocal micrographs showing lysosome labeling in human iPSC-

Updated on:April 26,2024

Alzheimer's disease is partly genetic—studying the genes that delay decline in some may lead to treatments for all

by Steven DeKosky,The ConversationCredit: Unsplash/CC0 Public DomainDiseases that run in families usually have genetic causes. Some aregenetic mutationsthat directly cause the diseas

Updated on: March 02,2024

Alzheimer's disease is partly genetic—studying the genes that delay decline in some may lead to treatments for all

by Steven DeKosky,The ConversationCredit: Unsplash/CC0 Public DomainDiseases that run in families usually have genetic causes. Some aregenetic mutationsthat directly cause the diseas

Updated on:March 02,2024

Scientists uncover new molecular drivers of Alzheimer's

by The Scripps Research InstituteA tiny glass tube (top left) represents the electrode recording from an excitatory human Alzheimer's neuron, generated using modern stem cell techniques (dark

Updated on: June 15,2024

Scientists uncover new molecular drivers of Alzheimer's

by The Scripps Research InstituteA tiny glass tube (top left) represents the electrode recording from an excitatory human Alzheimer's neuron, generated using modern stem cell techniques (dark

Updated on:June 15,2024

New studies suggest millions with mild cognitive impairment go undiagnosed, often until it's too late

by Soeren Mattke and Ying Liu,The ConversationCredit: Pixabay/CC0 Public DomainMild cognitive impairment—an early stage of dementia—is widely underdiagnosed in people 65 and older. That is the k

Updated on: March 28,2024

New studies suggest millions with mild cognitive impairment go undiagnosed, often until it's too late

by Soeren Mattke and Ying Liu,The ConversationCredit: Pixabay/CC0 Public DomainMild cognitive impairment—an early stage of dementia—is widely underdiagnosed in people 65 and older. That is the k

Updated on:March 28,2024

Is risk of Alzheimer's linked to specific sleep patterns?

by American Academy of NeurologyPET scan of a human brain with Alzheimer's disease. Credit: public domainDisturbed sleep patterns do not cause Alzheimer's disease but people who are at hi

Updated on: June 07,2024

Is risk of Alzheimer's linked to specific sleep patterns?

by American Academy of NeurologyPET scan of a human brain with Alzheimer's disease. Credit: public domainDisturbed sleep patterns do not cause Alzheimer's disease but people who are at hi

Updated on:June 07,2024

Stem cell scientists develop game-changing organoid model to study human cerebellar development and disease

byKeck School of Medicine of USCCredit: Pixabay/CC0 Public DomainIn a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato has pioneered a novel human brain organoid model that

Updated on: January 09,2024

Stem cell scientists develop game-changing organoid model to study human cerebellar development and disease

byKeck School of Medicine of USCCredit: Pixabay/CC0 Public DomainIn a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato has pioneered a novel human brain organoid model that

Updated on:January 09,2024

New hope against Alzheimer's disease

Updated on: December 25,2024

New hope against Alzheimer's disease

Updated on:December 25,2024

Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on: July 25,2024

Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on:July 25,2024