Molecule reduces multiple pathologies associated with Alzheimer's disease

by Diana Yates,University of Illinois at Urbana-ChampaignWhen tested in a mouse model of Alzheimer's disease, a new compound, L1, reduced neuroinflammation, amyloid plaques and other molecul

Updated on: June 01,2024

Molecule reduces multiple pathologies associated with Alzheimer's disease

by Diana Yates,University of Illinois at Urbana-ChampaignWhen tested in a mouse model of Alzheimer's disease, a new compound, L1, reduced neuroinflammation, amyloid plaques and other molecul

Updated on:June 01,2024

Researchers identify a new small molecule inhibitor for use against Alzheimer's disease

by Brandon Chase,Massachusetts General HospitalChemical properties, and synthesis of PB118. Credit:Advanced Science(2023). DOI: 10.1002/advs.202304545In people with Alzheimer's d

Updated on: February 24,2024

Researchers identify a new small molecule inhibitor for use against Alzheimer's disease

by Brandon Chase,Massachusetts General HospitalChemical properties, and synthesis of PB118. Credit:Advanced Science(2023). DOI: 10.1002/advs.202304545In people with Alzheimer's d

Updated on:February 24,2024

Brain imaging of tau protein in patients with various forms of dementia

by Cell PressThis figure shows associations between the Clinical Disease Severity and the Extent of Areas Showing Increased 18F-PM-PBB3 Binding in the AD Spectrum. Credit: Tagai, Ono, and Kubota

Updated on: May 05,2024

Brain imaging of tau protein in patients with various forms of dementia

by Cell PressThis figure shows associations between the Clinical Disease Severity and the Extent of Areas Showing Increased 18F-PM-PBB3 Binding in the AD Spectrum. Credit: Tagai, Ono, and Kubota

Updated on:May 05,2024

AI-based diagnostic tool differentiates dementia diseases by analysis of eye movement patterns

by University of TsukubaExamples of complex scene images with gaze densities derived from the CU, AD, and LBD groups. Results show that AD and LBD patients focused on fewer locations (A–D), had d

Updated on: June 15,2024

AI-based diagnostic tool differentiates dementia diseases by analysis of eye movement patterns

by University of TsukubaExamples of complex scene images with gaze densities derived from the CU, AD, and LBD groups. Results show that AD and LBD patients focused on fewer locations (A–D), had d

Updated on:June 15,2024

Driving with dementia—New guidance for doctors

by Newcastle UniversityNew guidelines have been published to help doctors and health care professionals assess and manage when people living with dementia should stop driving. Credit: Newcastle U

Updated on: May 09,2024

Driving with dementia—New guidance for doctors

by Newcastle UniversityNew guidelines have been published to help doctors and health care professionals assess and manage when people living with dementia should stop driving. Credit: Newcastle U

Updated on:May 09,2024

Controversial Alzheimer's drug should not be approved out of desperation, warn Aussie experts

by Medical Journal of AustraliaCredit: Unsplash/CC0 Public DomainAducanumab, a controversial Alzheimer's disease medication with "questionable efficacy," is under review by the Therapeut

Updated on: April 25,2024

Controversial Alzheimer's drug should not be approved out of desperation, warn Aussie experts

by Medical Journal of AustraliaCredit: Unsplash/CC0 Public DomainAducanumab, a controversial Alzheimer's disease medication with "questionable efficacy," is under review by the Therapeut

Updated on:April 25,2024

Interferon drives cognitive impairment in Alzheimer's disease model

by Baylor College of MedicineCredit: CC0 Public DomainAlzheimer's disease (AD), the most common type of dementia, progressively impairs memory, concentration and the ability to learn new thin

Updated on: June 04,2024

Interferon drives cognitive impairment in Alzheimer's disease model

by Baylor College of MedicineCredit: CC0 Public DomainAlzheimer's disease (AD), the most common type of dementia, progressively impairs memory, concentration and the ability to learn new thin

Updated on:June 04,2024

Researchers find connections between neuroinflammation and Alzheimer's disease

by Brigham and Women's HospitalINPP5D expression in the human brain is restricted to microglia in the human brain. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-4281

Updated on: June 19,2024

Researchers find connections between neuroinflammation and Alzheimer's disease

by Brigham and Women's HospitalINPP5D expression in the human brain is restricted to microglia in the human brain. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-4281

Updated on:June 19,2024

Broken brain cells repaired in dementia mouse model

by Society for NeuroscienceRepresentative images of the hippocampus and Entorhinal cortex. Credit: Terreros-Roncal et al.JNeurosci(2019)Dysfunctional neurons in the hippocampus of adu

Updated on: May 06,2024

Broken brain cells repaired in dementia mouse model

by Society for NeuroscienceRepresentative images of the hippocampus and Entorhinal cortex. Credit: Terreros-Roncal et al.JNeurosci(2019)Dysfunctional neurons in the hippocampus of adu

Updated on:May 06,2024

1 in 10 people with dementia experience suicidal thoughts, finds study

byUniversity College LondonForest plots of prevalence of suicide outcomes in PwD. Credit:Ageing Research Reviews(2024). DOI: 10.1016/j.arr.2024.102445People with dementia are more li

Updated on: September 21,2024

1 in 10 people with dementia experience suicidal thoughts, finds study

byUniversity College LondonForest plots of prevalence of suicide outcomes in PwD. Credit:Ageing Research Reviews(2024). DOI: 10.1016/j.arr.2024.102445People with dementia are more li

Updated on:September 21,2024

New drug candidate ameliorates Alzheimer's and other brain diseases

by Ludwig Maximilian University of MunichCredit: Jens WagnerProfessor Armin Giese from the Center for Neuropathology and Prion Research at the LMU Munich and researchers at the Max Planck Institu

Updated on: February 26,2024

New drug candidate ameliorates Alzheimer's and other brain diseases

by Ludwig Maximilian University of MunichCredit: Jens WagnerProfessor Armin Giese from the Center for Neuropathology and Prion Research at the LMU Munich and researchers at the Max Planck Institu

Updated on:February 26,2024

Adult-born dentate granule cells support the activity of hippocampal cell populations

by Ingrid Fadelli , Medical XpressConfocal image of the dentate gyrus (cyan), with labelled adult-born dentate granule cells (magenta). Image credit: Katja Hartwich/Stephen McHugh/David DupretThe dent

Updated on: February 05,2024

Adult-born dentate granule cells support the activity of hippocampal cell populations

by Ingrid Fadelli , Medical XpressConfocal image of the dentate gyrus (cyan), with labelled adult-born dentate granule cells (magenta). Image credit: Katja Hartwich/Stephen McHugh/David DupretThe dent

Updated on:February 05,2024