Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on: July 25,2024

Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on:July 25,2024

Optimizing chronic subdural hematoma treatment

by Cactus CommunicationsThe MRCSDH is the first nationwide study in mainland China to assess the safety and efficacy of different treatment approaches for CSDH. Its findings can help the medical commu

Updated on: April 06,2024

Optimizing chronic subdural hematoma treatment

by Cactus CommunicationsThe MRCSDH is the first nationwide study in mainland China to assess the safety and efficacy of different treatment approaches for CSDH. Its findings can help the medical commu

Updated on:April 06,2024

People with increased risk of Alzheimer's have deficits in navigating

by Ruhr-Universitaet-BochumCredit: Pixabay/CC0 Public DomainAnimals and humans have the ability to follow their own position in space through self-motion cues, even in the absence of any other se

Updated on: June 07,2024

People with increased risk of Alzheimer's have deficits in navigating

by Ruhr-Universitaet-BochumCredit: Pixabay/CC0 Public DomainAnimals and humans have the ability to follow their own position in space through self-motion cues, even in the absence of any other se

Updated on:June 07,2024

Study opens the door to earlier diagnosis and potential treatment for Alzheimer's disease

by Aarhus UniversityLarge Aβ Agg [+] MCI patients display lower AD-like brain pathology than large Aβ Agg [-] MCI.a18F-FTP PET uptake in each group at baseline, two-year follow-up, an

Updated on: March 19,2024

Study opens the door to earlier diagnosis and potential treatment for Alzheimer's disease

by Aarhus UniversityLarge Aβ Agg [+] MCI patients display lower AD-like brain pathology than large Aβ Agg [-] MCI.a18F-FTP PET uptake in each group at baseline, two-year follow-up, an

Updated on:March 19,2024

How does the brain make memories?

by Cedars-Sinai Medical CenterCredit: CC0 Public DomainIn a study led by Cedars-Sinai, researchers have discovered two types of brain cells that play a key role in dividing continuous human exper

Updated on: February 21,2024

How does the brain make memories?

by Cedars-Sinai Medical CenterCredit: CC0 Public DomainIn a study led by Cedars-Sinai, researchers have discovered two types of brain cells that play a key role in dividing continuous human exper

Updated on:February 21,2024

Dementia rates more than 20% higher among black adults than UK average

by University College LondonCrude dementia prevalence (95% CI) in those aged 65 and over, by ethnic group. Credit:Alzheimer's & Dementia(2022). DOI: 10.1002/alz.12774Dementia

Updated on: June 07,2024

Dementia rates more than 20% higher among black adults than UK average

by University College LondonCrude dementia prevalence (95% CI) in those aged 65 and over, by ethnic group. Credit:Alzheimer's & Dementia(2022). DOI: 10.1002/alz.12774Dementia

Updated on:June 07,2024

Post-COVID condition is not linked to ongoing infection or active brain damage, study shows

by Gustav Löfgren,Swedish Research CouncilPrincipal component analysis plot of 5 neurobiomarkers in CSF. The centroids for each group are indicated and surrounded with ellipses indicating 95% co

Updated on: January 11,2024

Post-COVID condition is not linked to ongoing infection or active brain damage, study shows

by Gustav Löfgren,Swedish Research CouncilPrincipal component analysis plot of 5 neurobiomarkers in CSF. The centroids for each group are indicated and surrounded with ellipses indicating 95% co

Updated on:January 11,2024

New findings on physical activity could shape treatment for mild Alzheimer's disease

by University of KansasResearchers say understanding daily patterns of physical activity could help design more effective interventions. Credit: KUFor older adults, physical activity is apt to sh

Updated on: June 05,2024

New findings on physical activity could shape treatment for mild Alzheimer's disease

by University of KansasResearchers say understanding daily patterns of physical activity could help design more effective interventions. Credit: KUFor older adults, physical activity is apt to sh

Updated on:June 05,2024

Researchers: Lifestyle changes can reduce dementia risk by maintaining brain plasticity, but the time to act is now

by Saskia Sivananthan and Laura Middleton,The ConversationCredit: CC0 Public DomainWalk 10,000 steps a day, cut back alcohol, get better sleep at night, stay socially active—we're told that

Updated on: February 24,2024

Researchers: Lifestyle changes can reduce dementia risk by maintaining brain plasticity, but the time to act is now

by Saskia Sivananthan and Laura Middleton,The ConversationCredit: CC0 Public DomainWalk 10,000 steps a day, cut back alcohol, get better sleep at night, stay socially active—we're told that

Updated on:February 24,2024

Adult-born dentate granule cells support the activity of hippocampal cell populations

by Ingrid Fadelli , Medical XpressConfocal image of the dentate gyrus (cyan), with labelled adult-born dentate granule cells (magenta). Image credit: Katja Hartwich/Stephen McHugh/David DupretThe dent

Updated on: February 05,2024

Adult-born dentate granule cells support the activity of hippocampal cell populations

by Ingrid Fadelli , Medical XpressConfocal image of the dentate gyrus (cyan), with labelled adult-born dentate granule cells (magenta). Image credit: Katja Hartwich/Stephen McHugh/David DupretThe dent

Updated on:February 05,2024

Molecular mechanism behind HIV-associated dementia revealed

by Will Doss,Northwestern UniversityThe interaction between APP (red) and GAG (green) in the cell. Credit: Northwestern UniversityFor the first time, scientists have identified and inhibited a m

Updated on: March 30,2024

Molecular mechanism behind HIV-associated dementia revealed

by Will Doss,Northwestern UniversityThe interaction between APP (red) and GAG (green) in the cell. Credit: Northwestern UniversityFor the first time, scientists have identified and inhibited a m

Updated on:March 30,2024

Advanced fMRI techniques reveal the brain's dynamic architecture

byMiguel Hernandez University of ElcheHierarchical distribution of connections represented in colors on the surface of a human brain. Credit: Varga, L. et al. inCell Systems(2024)Res

Updated on: September 23,2024

Advanced fMRI techniques reveal the brain's dynamic architecture

byMiguel Hernandez University of ElcheHierarchical distribution of connections represented in colors on the surface of a human brain. Credit: Varga, L. et al. inCell Systems(2024)Res

Updated on:September 23,2024