Report highlights scale of dementia epidemic in Africa

by King's College LondonCredit: King's College LondonAlzheimer's Disease International (ADI) has published its first report on the impact of dementia in sub-Saharan Africa (SSA), at i

Updated on: April 29,2024

Report highlights scale of dementia epidemic in Africa

by King's College LondonCredit: King's College LondonAlzheimer's Disease International (ADI) has published its first report on the impact of dementia in sub-Saharan Africa (SSA), at i

Updated on:April 29,2024

Unlocking the mystery of tau for treatment of neurodegenerative diseases

by Nagoya UniversityUnder normal physiological conditions, FUS and SFPQ interact in the nucleus of nerve cells and regulate the alternative splicing of MAPT by excising exon 10. When this functio

Updated on: July 01,2024

Unlocking the mystery of tau for treatment of neurodegenerative diseases

by Nagoya UniversityUnder normal physiological conditions, FUS and SFPQ interact in the nucleus of nerve cells and regulate the alternative splicing of MAPT by excising exon 10. When this functio

Updated on:July 01,2024

More appropriate support is needed for older residents with dementia in subsidized housing

by University of TorontoCredit: Pixabay/CC0 Public DomainA recent scoping review, published online in theJournal of Aging and Environment, found that older adults with dementia or cognitive

Updated on: May 26,2024

More appropriate support is needed for older residents with dementia in subsidized housing

by University of TorontoCredit: Pixabay/CC0 Public DomainA recent scoping review, published online in theJournal of Aging and Environment, found that older adults with dementia or cognitive

Updated on:May 26,2024

Alzheimer's disease is partly genetic—studying the genes that delay decline in some may lead to treatments for all

by Steven DeKosky,The ConversationCredit: Unsplash/CC0 Public DomainDiseases that run in families usually have genetic causes. Some aregenetic mutationsthat directly cause the diseas

Updated on: March 02,2024

Alzheimer's disease is partly genetic—studying the genes that delay decline in some may lead to treatments for all

by Steven DeKosky,The ConversationCredit: Unsplash/CC0 Public DomainDiseases that run in families usually have genetic causes. Some aregenetic mutationsthat directly cause the diseas

Updated on:March 02,2024

New studies suggest millions with mild cognitive impairment go undiagnosed, often until it's too late

by Soeren Mattke and Ying Liu,The ConversationCredit: Pixabay/CC0 Public DomainMild cognitive impairment—an early stage of dementia—is widely underdiagnosed in people 65 and older. That is the k

Updated on: March 28,2024

New studies suggest millions with mild cognitive impairment go undiagnosed, often until it's too late

by Soeren Mattke and Ying Liu,The ConversationCredit: Pixabay/CC0 Public DomainMild cognitive impairment—an early stage of dementia—is widely underdiagnosed in people 65 and older. That is the k

Updated on:March 28,2024

Stretchable probe measures brain chemicals central to Parkinson's, depression, and gut disease

by Stanford UniversityResearchers demonstrated the advantages of the flexible and elastic NeuroString technology by threading a probe through a segment of mouse colon. Credit: Zhenan Bao labImbal

Updated on: June 03,2024

Stretchable probe measures brain chemicals central to Parkinson's, depression, and gut disease

by Stanford UniversityResearchers demonstrated the advantages of the flexible and elastic NeuroString technology by threading a probe through a segment of mouse colon. Credit: Zhenan Bao labImbal

Updated on:June 03,2024

Hippocampal study unveils distinct protein machineries for calcium channel clustering and vesicle priming

by Ingrid Fadelli , Medical XpressMunc13-1 and CaV2.1 nanoclustering. a–c, Example STED images of sideview synapses (a), quantification of line profiles (b) and Pearson's colocalization coefficien

Updated on: September 23,2024

Hippocampal study unveils distinct protein machineries for calcium channel clustering and vesicle priming

by Ingrid Fadelli , Medical XpressMunc13-1 and CaV2.1 nanoclustering. a–c, Example STED images of sideview synapses (a), quantification of line profiles (b) and Pearson's colocalization coefficien

Updated on:September 23,2024

Early-life exposure to manganese may be beneficial to adolescent cognition

by Jillian McKoy,Boston UniversityAdjusted beta (β) estimates and 95% CIs from multivariable linear regression models assessing associations between prenatal, postnatal, and childhood tooth Mn l

Updated on: January 10,2024

Early-life exposure to manganese may be beneficial to adolescent cognition

by Jillian McKoy,Boston UniversityAdjusted beta (β) estimates and 95% CIs from multivariable linear regression models assessing associations between prenatal, postnatal, and childhood tooth Mn l

Updated on:January 10,2024

Study reveals insights into link between genetic mutation and Parkinson's

by Bill Hathaway,Yale UniversityLRRK2 inhibits lysosomal protease activity in human iPSC-derived macrophages. (A) Airyscan live cell confocal micrographs showing lysosome labeling in human iPSC-

Updated on: April 26,2024

Study reveals insights into link between genetic mutation and Parkinson's

by Bill Hathaway,Yale UniversityLRRK2 inhibits lysosomal protease activity in human iPSC-derived macrophages. (A) Airyscan live cell confocal micrographs showing lysosome labeling in human iPSC-

Updated on:April 26,2024

Novel cause of brain mosaicism and focal epilepsy identified

byNationwide Children's HospitalBrain mosaic copy number gain of chr1q.a, Six patients included in the study met the following criteria: infantile spasms progressing to intractable foc

Updated on: January 12,2024

Novel cause of brain mosaicism and focal epilepsy identified

byNationwide Children's HospitalBrain mosaic copy number gain of chr1q.a, Six patients included in the study met the following criteria: infantile spasms progressing to intractable foc

Updated on:January 12,2024

Power of illusion can help with learning new movements

by Tokyo Metropolitan UniversitySet up of each condition. Participants were seated in a chair with their left upper limb placed on a table and maintained in a resting position. (a) The Visual-mot

Updated on: February 18,2024

Power of illusion can help with learning new movements

by Tokyo Metropolitan UniversitySet up of each condition. Participants were seated in a chair with their left upper limb placed on a table and maintained in a resting position. (a) The Visual-mot

Updated on:February 18,2024

Prospects continue to improve for people with MS, but disease management in older adults presents challenges

by Ellen Goldbaum,University at BuffaloCredit: Anna Shvets from PexelsThe past five years have seen significant advancements in diagnosing and treating multiple sclerosis (MS), but challenges re

Updated on: January 10,2024

Prospects continue to improve for people with MS, but disease management in older adults presents challenges

by Ellen Goldbaum,University at BuffaloCredit: Anna Shvets from PexelsThe past five years have seen significant advancements in diagnosing and treating multiple sclerosis (MS), but challenges re

Updated on:January 10,2024