Hippocampal study unveils distinct protein machineries for calcium channel clustering and vesicle priming

by Ingrid Fadelli , Medical XpressMunc13-1 and CaV2.1 nanoclustering. a–c, Example STED images of sideview synapses (a), quantification of line profiles (b) and Pearson's colocalization coefficien

Updated on: September 23,2024

Hippocampal study unveils distinct protein machineries for calcium channel clustering and vesicle priming

by Ingrid Fadelli , Medical XpressMunc13-1 and CaV2.1 nanoclustering. a–c, Example STED images of sideview synapses (a), quantification of line profiles (b) and Pearson's colocalization coefficien

Updated on:September 23,2024

Brain stimulation can rewire and heal damaged neural connections, but it isn't clear how

by Azadeh Yazdan-Shahmorad, Alec Greaves-Tunnell and Julien Bloch,The ConversationDeep-brain stimulation is one form of neurostimulation currently used to treat Parkinson’s and depression.The co

Updated on: February 21,2024

Brain stimulation can rewire and heal damaged neural connections, but it isn't clear how

by Azadeh Yazdan-Shahmorad, Alec Greaves-Tunnell and Julien Bloch,The ConversationDeep-brain stimulation is one form of neurostimulation currently used to treat Parkinson’s and depression.The co

Updated on:February 21,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on: February 05,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on:February 05,2024

From molecular to whole-brain scale in a simple animal, study reveals serotonin's effects

byMassachusetts Institute of TechnologyA 3D rendering of a C. elegans worm, mapping all of its neurons. Credit: Steve Flavell/MIT Picower InstituteBecause serotonin is one of the primary chemica

Updated on: February 18,2024

From molecular to whole-brain scale in a simple animal, study reveals serotonin's effects

byMassachusetts Institute of TechnologyA 3D rendering of a C. elegans worm, mapping all of its neurons. Credit: Steve Flavell/MIT Picower InstituteBecause serotonin is one of the primary chemica

Updated on:February 18,2024

AI-based diagnostic tool differentiates dementia diseases by analysis of eye movement patterns

by University of TsukubaExamples of complex scene images with gaze densities derived from the CU, AD, and LBD groups. Results show that AD and LBD patients focused on fewer locations (A–D), had d

Updated on: June 15,2024

AI-based diagnostic tool differentiates dementia diseases by analysis of eye movement patterns

by University of TsukubaExamples of complex scene images with gaze densities derived from the CU, AD, and LBD groups. Results show that AD and LBD patients focused on fewer locations (A–D), had d

Updated on:June 15,2024

Risk gene for Alzheimer's has early effects on the brain

by German Center for Neurodegenerative DiseasesCredit: Pixabay/CC0 Public DomainA genetic predisposition to late-onset Alzheimer's disease affects how the brains of young adults cope with cer

Updated on: April 18,2024

Risk gene for Alzheimer's has early effects on the brain

by German Center for Neurodegenerative DiseasesCredit: Pixabay/CC0 Public DomainA genetic predisposition to late-onset Alzheimer's disease affects how the brains of young adults cope with cer

Updated on:April 18,2024

Targeting the LANDO pathway holds a potential clue to treating Alzheimer's disease

by St. Jude Children's Research HospitalBradlee Heckmann, Ph.D., of St. Jude Immunology. Credit: St. Jude Children's Research HospitalScientists at St. Jude Children's Research Hospit

Updated on: April 25,2024

Targeting the LANDO pathway holds a potential clue to treating Alzheimer's disease

by St. Jude Children's Research HospitalBradlee Heckmann, Ph.D., of St. Jude Immunology. Credit: St. Jude Children's Research HospitalScientists at St. Jude Children's Research Hospit

Updated on:April 25,2024

Improving the lives of people with dementia

by Cardiff UniversityCredit: CC0 Public DomainAn expert in the communication challenges caused by dementia is using her research to inform training practices for carers and families.Professor Ali

Updated on: June 04,2024

Improving the lives of people with dementia

by Cardiff UniversityCredit: CC0 Public DomainAn expert in the communication challenges caused by dementia is using her research to inform training practices for carers and families.Professor Ali

Updated on:June 04,2024

Researchers uncover shared cellular mechanisms across three major dementias

byUniversity of California, Los AngelesCredit: Pixabay/CC0 Public DomainResearchers have for the first time identified degeneration-associated "molecular markers"—observable changes in

Updated on: September 15,2024

Researchers uncover shared cellular mechanisms across three major dementias

byUniversity of California, Los AngelesCredit: Pixabay/CC0 Public DomainResearchers have for the first time identified degeneration-associated "molecular markers"—observable changes in

Updated on:September 15,2024

More appropriate support is needed for older residents with dementia in subsidized housing

by University of TorontoCredit: Pixabay/CC0 Public DomainA recent scoping review, published online in theJournal of Aging and Environment, found that older adults with dementia or cognitive

Updated on: May 26,2024

More appropriate support is needed for older residents with dementia in subsidized housing

by University of TorontoCredit: Pixabay/CC0 Public DomainA recent scoping review, published online in theJournal of Aging and Environment, found that older adults with dementia or cognitive

Updated on:May 26,2024

Scientists identify mutated gene behind mirror movement disorder

byUniversity of MontrealArhgef7 is required for Netrin-1–mediated commissural axon guidance. (A) The mean mRNA expression, fragments per kilobase of transcript per million mapped reads (fpkm), (

Updated on: April 22,2024

Scientists identify mutated gene behind mirror movement disorder

byUniversity of MontrealArhgef7 is required for Netrin-1–mediated commissural axon guidance. (A) The mean mRNA expression, fragments per kilobase of transcript per million mapped reads (fpkm), (

Updated on:April 22,2024

Cardiovascular drugs may reduce dementia risk

byKarolinska InstitutetCredit: Unsplash/CC0 Public DomainCommon cardiovascular drugs are linked to a lower risk of dementia in older age, according to anew studyfrom Karolinska Insti

Updated on: November 28,2024

Cardiovascular drugs may reduce dementia risk

byKarolinska InstitutetCredit: Unsplash/CC0 Public DomainCommon cardiovascular drugs are linked to a lower risk of dementia in older age, according to anew studyfrom Karolinska Insti

Updated on:November 28,2024