'Viral relicts' in the genome could fuel neurodegeneration

by Marcus Neitzert, Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)Different HERV glycoproteins increase intercellular protein aggregate spreading.aExperimental workflow.

Updated on: June 18,2024

'Viral relicts' in the genome could fuel neurodegeneration

by Marcus Neitzert, Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)Different HERV glycoproteins increase intercellular protein aggregate spreading.aExperimental workflow.

Updated on:June 18,2024

Risk gene for Alzheimer's has early effects on the brain

by German Center for Neurodegenerative DiseasesCredit: Pixabay/CC0 Public DomainA genetic predisposition to late-onset Alzheimer's disease affects how the brains of young adults cope with cer

Updated on: April 18,2024

Risk gene for Alzheimer's has early effects on the brain

by German Center for Neurodegenerative DiseasesCredit: Pixabay/CC0 Public DomainA genetic predisposition to late-onset Alzheimer's disease affects how the brains of young adults cope with cer

Updated on:April 18,2024

Broken brain cells repaired in dementia mouse model

by Society for NeuroscienceRepresentative images of the hippocampus and Entorhinal cortex. Credit: Terreros-Roncal et al.JNeurosci(2019)Dysfunctional neurons in the hippocampus of adu

Updated on: May 06,2024

Broken brain cells repaired in dementia mouse model

by Society for NeuroscienceRepresentative images of the hippocampus and Entorhinal cortex. Credit: Terreros-Roncal et al.JNeurosci(2019)Dysfunctional neurons in the hippocampus of adu

Updated on:May 06,2024

ALS and frontotemporal dementia: Early diagnosis thanks to an experimental test

by International School of Advanced Studies (SISSA)The scientists developed an experimental technique able to detect the protein TDP-43 even when it is present in the body in minute quantities an

Updated on: June 14,2024

ALS and frontotemporal dementia: Early diagnosis thanks to an experimental test

by International School of Advanced Studies (SISSA)The scientists developed an experimental technique able to detect the protein TDP-43 even when it is present in the body in minute quantities an

Updated on:June 14,2024

Using prebiotics to help treat Parkinson's disease

by Ariana Baldassano,Rush University Medical CenterTen days of the prebiotic intervention had effects on biological outcomes. Credit:Nature Communications(2023). DOI: 10.1038/s41467-

Updated on: May 21,2024

Using prebiotics to help treat Parkinson's disease

by Ariana Baldassano,Rush University Medical CenterTen days of the prebiotic intervention had effects on biological outcomes. Credit:Nature Communications(2023). DOI: 10.1038/s41467-

Updated on:May 21,2024

No cure for Alzheimer's disease in my lifetime

by Norman A. Paradis,The ConversationCredit: SAM LIN from PexelsBiogen recently announced that it was abandoning its late stage drug for Alzheimer's,aducanumab, causing investors to&nb

Updated on: April 16,2024

No cure for Alzheimer's disease in my lifetime

by Norman A. Paradis,The ConversationCredit: SAM LIN from PexelsBiogen recently announced that it was abandoning its late stage drug for Alzheimer's,aducanumab, causing investors to&nb

Updated on:April 16,2024

Scientists find a determining mechanism for synapse formation in the cerebellum

byMiguel Hernandez University of ElcheExpansion microscopy image with synaptic boutons (green) of climbing fibers on a Purkinje cell (blue) from the cerebellum of a mouse. Credit: CC BY IN-CSIC-

Updated on: July 11,2024

Scientists find a determining mechanism for synapse formation in the cerebellum

byMiguel Hernandez University of ElcheExpansion microscopy image with synaptic boutons (green) of climbing fibers on a Purkinje cell (blue) from the cerebellum of a mouse. Credit: CC BY IN-CSIC-

Updated on:July 11,2024

Dementia kills nearly three times more people than previously thought

by Boston University School of MedicineCredit: CC0 Public DomainDementia may be an underlying cause of nearly three times more deaths in the U.S. than official records show, according to a new Bo

Updated on: May 06,2024

Dementia kills nearly three times more people than previously thought

by Boston University School of MedicineCredit: CC0 Public DomainDementia may be an underlying cause of nearly three times more deaths in the U.S. than official records show, according to a new Bo

Updated on:May 06,2024

More appropriate support is needed for older residents with dementia in subsidized housing

by University of TorontoCredit: Pixabay/CC0 Public DomainA recent scoping review, published online in theJournal of Aging and Environment, found that older adults with dementia or cognitive

Updated on: May 26,2024

More appropriate support is needed for older residents with dementia in subsidized housing

by University of TorontoCredit: Pixabay/CC0 Public DomainA recent scoping review, published online in theJournal of Aging and Environment, found that older adults with dementia or cognitive

Updated on:May 26,2024

Secret structure in the wiring diagram of the brain

by Petra Sandow,University of BonnCredit: UKB & LMU / Dr. Nataliya Kraynyukova; Dr. Simon RennerIn the brain, our perception arises from a complex interplay of neurons that are connected via

Updated on: February 21,2024

Secret structure in the wiring diagram of the brain

by Petra Sandow,University of BonnCredit: UKB & LMU / Dr. Nataliya Kraynyukova; Dr. Simon RennerIn the brain, our perception arises from a complex interplay of neurons that are connected via

Updated on:February 21,2024

Epigenetic 'age' predicts cognitive function

by Will Doss,Northwestern UniversityCredit: Unsplash/CC0 Public DomainEpigenetic markers of cognitive aging can predict performance on cognitive tests later in life, according to a study publish

Updated on: April 29,2024

Epigenetic 'age' predicts cognitive function

by Will Doss,Northwestern UniversityCredit: Unsplash/CC0 Public DomainEpigenetic markers of cognitive aging can predict performance on cognitive tests later in life, according to a study publish

Updated on:April 29,2024

Study reveals insights into link between genetic mutation and Parkinson's

by Bill Hathaway,Yale UniversityLRRK2 inhibits lysosomal protease activity in human iPSC-derived macrophages. (A) Airyscan live cell confocal micrographs showing lysosome labeling in human iPSC-

Updated on: April 26,2024

Study reveals insights into link between genetic mutation and Parkinson's

by Bill Hathaway,Yale UniversityLRRK2 inhibits lysosomal protease activity in human iPSC-derived macrophages. (A) Airyscan live cell confocal micrographs showing lysosome labeling in human iPSC-

Updated on:April 26,2024