Hippocampal study unveils distinct protein machineries for calcium channel clustering and vesicle priming

by Ingrid Fadelli , Medical XpressMunc13-1 and CaV2.1 nanoclustering. a–c, Example STED images of sideview synapses (a), quantification of line profiles (b) and Pearson's colocalization coefficien

Updated on: September 23,2024

Hippocampal study unveils distinct protein machineries for calcium channel clustering and vesicle priming

by Ingrid Fadelli , Medical XpressMunc13-1 and CaV2.1 nanoclustering. a–c, Example STED images of sideview synapses (a), quantification of line profiles (b) and Pearson's colocalization coefficien

Updated on:September 23,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on: February 05,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on:February 05,2024

How SORLA protects against Alzheimer's disease

by Sanford-Burnham Prebys Medical Discovery InstituteHuaxi Xu, Ph.D., Professor, Neuroscience and Aging Research Center. Credit: Sanford Burnham Prebys Medical Discovery Institute (SBP)Researcher

Updated on: April 02,2024

How SORLA protects against Alzheimer's disease

by Sanford-Burnham Prebys Medical Discovery InstituteHuaxi Xu, Ph.D., Professor, Neuroscience and Aging Research Center. Credit: Sanford Burnham Prebys Medical Discovery Institute (SBP)Researcher

Updated on:April 02,2024

Improving the lives of people with dementia

by Cardiff UniversityCredit: CC0 Public DomainAn expert in the communication challenges caused by dementia is using her research to inform training practices for carers and families.Professor Ali

Updated on: June 04,2024

Improving the lives of people with dementia

by Cardiff UniversityCredit: CC0 Public DomainAn expert in the communication challenges caused by dementia is using her research to inform training practices for carers and families.Professor Ali

Updated on:June 04,2024

Research offers insight into future understanding of MS and its treatments

byTrinity College DublinComparison of EBNA-1 IgG Levels in Healthy Controls and People With MS and Epilepsy. Credit:Neurology Neuroimmunology & Neuroinflammation(2024). DOI: 10.1

Updated on: April 06,2024

Research offers insight into future understanding of MS and its treatments

byTrinity College DublinComparison of EBNA-1 IgG Levels in Healthy Controls and People With MS and Epilepsy. Credit:Neurology Neuroimmunology & Neuroinflammation(2024). DOI: 10.1

Updated on:April 06,2024

Unlocking how the new Alzheimer's drug lecanemab works

by Rockefeller UniversityA false-color SEM image of a fibrin blood clot before and after the buildup of amyloid-beta proteins called protofibrils. Credit: Pradeep Singh, PhD; Images collected at

Updated on: March 02,2024

Unlocking how the new Alzheimer's drug lecanemab works

by Rockefeller UniversityA false-color SEM image of a fibrin blood clot before and after the buildup of amyloid-beta proteins called protofibrils. Credit: Pradeep Singh, PhD; Images collected at

Updated on:March 02,2024

Better than a hole in the head: Modernizing intracranial pressure sensing methods

by Sara Vaccar,Carnegie Mellon UniversityCredit: Carnegie Mellon UniversityJust as blood pressure informs heart health, intracranial pressure (ICP) helps indicate brain health. ICP sensing is th

Updated on: February 03,2024

Better than a hole in the head: Modernizing intracranial pressure sensing methods

by Sara Vaccar,Carnegie Mellon UniversityCredit: Carnegie Mellon UniversityJust as blood pressure informs heart health, intracranial pressure (ICP) helps indicate brain health. ICP sensing is th

Updated on:February 03,2024

Altered gut bacteria may be early sign of Alzheimer's disease

by Washington University School of MedicineCredit: Unsplash/CC0 Public DomainPeople in the earliest stage of Alzheimer's disease—after brain changes have begun but before cognitive symptoms b

Updated on: May 05,2024

Altered gut bacteria may be early sign of Alzheimer's disease

by Washington University School of MedicineCredit: Unsplash/CC0 Public DomainPeople in the earliest stage of Alzheimer's disease—after brain changes have begun but before cognitive symptoms b

Updated on:May 05,2024

Specific brain responses to traumatic stress linked to PTSD risk

by University of North Carolina Health CareCredit: CC0 Public DomainResults from the largest prospective study of its kind indicate that in the initial days and weeks after experiencing trauma, i

Updated on: February 21,2024

Specific brain responses to traumatic stress linked to PTSD risk

by University of North Carolina Health CareCredit: CC0 Public DomainResults from the largest prospective study of its kind indicate that in the initial days and weeks after experiencing trauma, i

Updated on:February 21,2024

Depression symptoms in Alzheimer's could be signs for cognitive decline

by Massachusetts General HospitalCredit: CC0 Public DomainBOSTON -Increasingly, Alzheimer's disease (AD) research has focused on the preclinical stage, when people have biological evidence of

Updated on: April 18,2024

Depression symptoms in Alzheimer's could be signs for cognitive decline

by Massachusetts General HospitalCredit: CC0 Public DomainBOSTON -Increasingly, Alzheimer's disease (AD) research has focused on the preclinical stage, when people have biological evidence of

Updated on:April 18,2024

Nanoscopic motor proteins in the brain build the physical structures of memory, study finds

by Albert HiuKa Fok,The ConversationCredit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113906The puzzle of memory has intrigued philosophers and intellects for a very long time. P

Updated on: July 06,2024

Nanoscopic motor proteins in the brain build the physical structures of memory, study finds

by Albert HiuKa Fok,The ConversationCredit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113906The puzzle of memory has intrigued philosophers and intellects for a very long time. P

Updated on:July 06,2024

Different pain types in multiple sclerosis can cause difficulty staying active

by Valerie Goodwin,University of MichiganCredit: CC0 Public DomainFor patients with multiple sclerosis, a regular exercise routine is important for managing symptoms. But due to different causes

Updated on: January 11,2024

Different pain types in multiple sclerosis can cause difficulty staying active

by Valerie Goodwin,University of MichiganCredit: CC0 Public DomainFor patients with multiple sclerosis, a regular exercise routine is important for managing symptoms. But due to different causes

Updated on:January 11,2024