Study reveals insights into link between genetic mutation and Parkinson's

by Bill Hathaway,Yale UniversityLRRK2 inhibits lysosomal protease activity in human iPSC-derived macrophages. (A) Airyscan live cell confocal micrographs showing lysosome labeling in human iPSC-

Updated on: April 26,2024

Study reveals insights into link between genetic mutation and Parkinson's

by Bill Hathaway,Yale UniversityLRRK2 inhibits lysosomal protease activity in human iPSC-derived macrophages. (A) Airyscan live cell confocal micrographs showing lysosome labeling in human iPSC-

Updated on:April 26,2024

Optimizing chronic subdural hematoma treatment

by Cactus CommunicationsThe MRCSDH is the first nationwide study in mainland China to assess the safety and efficacy of different treatment approaches for CSDH. Its findings can help the medical commu

Updated on: April 06,2024

Optimizing chronic subdural hematoma treatment

by Cactus CommunicationsThe MRCSDH is the first nationwide study in mainland China to assess the safety and efficacy of different treatment approaches for CSDH. Its findings can help the medical commu

Updated on:April 06,2024

Hippocampal study unveils distinct protein machineries for calcium channel clustering and vesicle priming

by Ingrid Fadelli , Medical XpressMunc13-1 and CaV2.1 nanoclustering. a–c, Example STED images of sideview synapses (a), quantification of line profiles (b) and Pearson's colocalization coefficien

Updated on: September 23,2024

Hippocampal study unveils distinct protein machineries for calcium channel clustering and vesicle priming

by Ingrid Fadelli , Medical XpressMunc13-1 and CaV2.1 nanoclustering. a–c, Example STED images of sideview synapses (a), quantification of line profiles (b) and Pearson's colocalization coefficien

Updated on:September 23,2024

Gene-editing tools pave way for new Alzheimer's treatments

by Cara MurezTwo new studies using CRISPR gene editing offer potential new treatments for Alzheimer's disease."A pipeline of potential new treatments offers hope for the Alzheimer's and d

Updated on: June 14,2024

Gene-editing tools pave way for new Alzheimer's treatments

by Cara MurezTwo new studies using CRISPR gene editing offer potential new treatments for Alzheimer's disease."A pipeline of potential new treatments offers hope for the Alzheimer's and d

Updated on:June 14,2024

Early-life exposure to manganese may be beneficial to adolescent cognition

by Jillian McKoy,Boston UniversityAdjusted beta (β) estimates and 95% CIs from multivariable linear regression models assessing associations between prenatal, postnatal, and childhood tooth Mn l

Updated on: January 10,2024

Early-life exposure to manganese may be beneficial to adolescent cognition

by Jillian McKoy,Boston UniversityAdjusted beta (β) estimates and 95% CIs from multivariable linear regression models assessing associations between prenatal, postnatal, and childhood tooth Mn l

Updated on:January 10,2024

Innovative method identifies rare brain cell types for the first time

by Katherine Fenz,Rockefeller UniversityEasySci enables high-throughput and low-cost single-cell transcriptome and chromatin accessibility profiling across the entire mammalian brain. Credit:&nb

Updated on: February 05,2024

Innovative method identifies rare brain cell types for the first time

by Katherine Fenz,Rockefeller UniversityEasySci enables high-throughput and low-cost single-cell transcriptome and chromatin accessibility profiling across the entire mammalian brain. Credit:&nb

Updated on:February 05,2024

Unlocking the mystery of tau for treatment of neurodegenerative diseases

by Nagoya UniversityUnder normal physiological conditions, FUS and SFPQ interact in the nucleus of nerve cells and regulate the alternative splicing of MAPT by excising exon 10. When this functio

Updated on: July 01,2024

Unlocking the mystery of tau for treatment of neurodegenerative diseases

by Nagoya UniversityUnder normal physiological conditions, FUS and SFPQ interact in the nucleus of nerve cells and regulate the alternative splicing of MAPT by excising exon 10. When this functio

Updated on:July 01,2024

Novel cause of brain mosaicism and focal epilepsy identified

byNationwide Children's HospitalBrain mosaic copy number gain of chr1q.a, Six patients included in the study met the following criteria: infantile spasms progressing to intractable foc

Updated on: January 12,2024

Novel cause of brain mosaicism and focal epilepsy identified

byNationwide Children's HospitalBrain mosaic copy number gain of chr1q.a, Six patients included in the study met the following criteria: infantile spasms progressing to intractable foc

Updated on:January 12,2024

Stretchable probe measures brain chemicals central to Parkinson's, depression, and gut disease

by Stanford UniversityResearchers demonstrated the advantages of the flexible and elastic NeuroString technology by threading a probe through a segment of mouse colon. Credit: Zhenan Bao labImbal

Updated on: June 03,2024

Stretchable probe measures brain chemicals central to Parkinson's, depression, and gut disease

by Stanford UniversityResearchers demonstrated the advantages of the flexible and elastic NeuroString technology by threading a probe through a segment of mouse colon. Credit: Zhenan Bao labImbal

Updated on:June 03,2024

Power of illusion can help with learning new movements

by Tokyo Metropolitan UniversitySet up of each condition. Participants were seated in a chair with their left upper limb placed on a table and maintained in a resting position. (a) The Visual-mot

Updated on: February 18,2024

Power of illusion can help with learning new movements

by Tokyo Metropolitan UniversitySet up of each condition. Participants were seated in a chair with their left upper limb placed on a table and maintained in a resting position. (a) The Visual-mot

Updated on:February 18,2024

Investigating specific pathological features of cerebral cavernous malformation in children

by Katie Paradis,Children's Hospital BostonCredit: CC0 Public DomainChildren with cavernous malformations face unique treatment challenges due to factors such as the malformation's locat

Updated on: November 28,2024

Investigating specific pathological features of cerebral cavernous malformation in children

by Katie Paradis,Children's Hospital BostonCredit: CC0 Public DomainChildren with cavernous malformations face unique treatment challenges due to factors such as the malformation's locat

Updated on:November 28,2024

New hope against Alzheimer's disease

Updated on: December 25,2024

New hope against Alzheimer's disease

Updated on:December 25,2024