A naturally-occurring molecule shows promise as effective first-line treatment for prostate cancer

JANUARY 5, 2024byNottingham Trent UniversityLive-cell cytotoxicity analysis shows that carnosine induces the death of PC346Flu1 (A) and TRAMP-C1 (B) cells. Carnosine inhibited cell growth in a d

Updated on: March 28,2024

A naturally-occurring molecule shows promise as effective first-line treatment for prostate cancer

JANUARY 5, 2024byNottingham Trent UniversityLive-cell cytotoxicity analysis shows that carnosine induces the death of PC346Flu1 (A) and TRAMP-C1 (B) cells. Carnosine inhibited cell growth in a d

Updated on:March 28,2024

How the tumor microenvironment stimulates pancreatic cancer growth and progression

by Nancy Fliesler,Children's Hospital BostonMyeloid-specific deletion of LRP1 inhibits tumor growth by preventing the repression of Tsp-1. A Plot of percentage of LRP1 + multiple myeloid and

Updated on: January 22,2024

How the tumor microenvironment stimulates pancreatic cancer growth and progression

by Nancy Fliesler,Children's Hospital BostonMyeloid-specific deletion of LRP1 inhibits tumor growth by preventing the repression of Tsp-1. A Plot of percentage of LRP1 + multiple myeloid and

Updated on:January 22,2024

Researchers show aspirin added to cancer drug improves effectiveness

by University of QueenslandCredit: University of QueenslandAdding aspirin to some existing cancer drugs could increase their effectiveness against a group of tumours resistant to treatment, new r

Updated on: March 01,2024

Researchers show aspirin added to cancer drug improves effectiveness

by University of QueenslandCredit: University of QueenslandAdding aspirin to some existing cancer drugs could increase their effectiveness against a group of tumours resistant to treatment, new r

Updated on:March 01,2024

Researchers unravel the mechanisms of Epstein-Barr virus and host chromatin interactions in nasopharyngeal cancer

byChiba UniversityEBV interacts at specific locations within the B compartment of the host chromatin structure and hijacks gene enhancers. The activation of enhancers activates the expression of

Updated on: March 30,2024

Researchers unravel the mechanisms of Epstein-Barr virus and host chromatin interactions in nasopharyngeal cancer

byChiba UniversityEBV interacts at specific locations within the B compartment of the host chromatin structure and hijacks gene enhancers. The activation of enhancers activates the expression of

Updated on:March 30,2024

Cooling glioblastoma to room temperature extends survival in preclinical study

by Jenny Owen,Emory UniversityConceptual model of a translational device to deliver cytostatic hypothermia for GBM. Representative diagram of a patient with GBM implanted with an envisioned cyto

Updated on: January 30,2024

Cooling glioblastoma to room temperature extends survival in preclinical study

by Jenny Owen,Emory UniversityConceptual model of a translational device to deliver cytostatic hypothermia for GBM. Representative diagram of a patient with GBM implanted with an envisioned cyto

Updated on:January 30,2024

'Collateral damage' from normal cell function may cause mutations that play a role in cancer

by Wellcome Trust Sanger InstituteSpatial distribution of APOBEC-positive crypts. APOBEC-positive crypts and their surrounding crypts before microdissection with their SBS mutational spectrums. S

Updated on: February 18,2024

'Collateral damage' from normal cell function may cause mutations that play a role in cancer

by Wellcome Trust Sanger InstituteSpatial distribution of APOBEC-positive crypts. APOBEC-positive crypts and their surrounding crypts before microdissection with their SBS mutational spectrums. S

Updated on:February 18,2024

Study finds education and navigation increase cancer genetic counseling and/or testing

by Rutgers Cancer Institute of New JerseyGraphical depiction of TP and TCN interventions. (a) Baseline survey, which captured sociodemographic information (age, rural status, etc), self-reported healt

Updated on: January 23,2024

Study finds education and navigation increase cancer genetic counseling and/or testing

by Rutgers Cancer Institute of New JerseyGraphical depiction of TP and TCN interventions. (a) Baseline survey, which captured sociodemographic information (age, rural status, etc), self-reported healt

Updated on:January 23,2024

Primary pancreatic organoid tumor models for high-throughput phenotypic drug screening

by SLAS (Society for Laboratory Automation and Screening)A Z-stack image was obtained after staining nuclei with Hoechst using confocal microscopy at 5 micron intervals and then assembled using ImageJ

Updated on: May 09,2024

Primary pancreatic organoid tumor models for high-throughput phenotypic drug screening

by SLAS (Society for Laboratory Automation and Screening)A Z-stack image was obtained after staining nuclei with Hoechst using confocal microscopy at 5 micron intervals and then assembled using ImageJ

Updated on:May 09,2024

New genetic testing pathways could ensure patients get personalized BRCA-linked cancer treatments

byInstitute of Cancer ResearchThe BRCA-DIRECT Pathway. Credit:British Journal of Cancer(2024). DOI: 10.1038/s41416-024-02832-2Scientists have developed a new clinical pathway for tes

Updated on: October 24,2024

New genetic testing pathways could ensure patients get personalized BRCA-linked cancer treatments

byInstitute of Cancer ResearchThe BRCA-DIRECT Pathway. Credit:British Journal of Cancer(2024). DOI: 10.1038/s41416-024-02832-2Scientists have developed a new clinical pathway for tes

Updated on:October 24,2024

Accurate assessment of heart rhythm can optimize chemotherapy use

byUNC Lineberger Comprehensive Cancer CenterCredit: Pixabay/CC0 Public DomainUsing the wrong mathematical formula to assess heartbeat rhythms may lead oncologists to inappropriately stop life-sa

Updated on: January 22,2024

Accurate assessment of heart rhythm can optimize chemotherapy use

byUNC Lineberger Comprehensive Cancer CenterCredit: Pixabay/CC0 Public DomainUsing the wrong mathematical formula to assess heartbeat rhythms may lead oncologists to inappropriately stop life-sa

Updated on:January 22,2024

Researchers use microscopy plus deep learning to advance prostate cancer diagnosis

by SPIEMicroscopic glands of the prostate are segmented (colored) with the new deep-learning pipeline; the image shows a prostate cancer tissue volume, measuring roughly 1 x 1 x 2 mm in size. The

Updated on: March 20,2024

Researchers use microscopy plus deep learning to advance prostate cancer diagnosis

by SPIEMicroscopic glands of the prostate are segmented (colored) with the new deep-learning pipeline; the image shows a prostate cancer tissue volume, measuring roughly 1 x 1 x 2 mm in size. The

Updated on:March 20,2024

Expert discusses the impact and potential of cancer prevention

by Anne Trafton,Massachusetts Institute of TechnologyGreat progress has been made in reducing the cancer death toll through better prevention and screening, according to a new article by MIT Pro

Updated on: April 01,2024

Expert discusses the impact and potential of cancer prevention

by Anne Trafton,Massachusetts Institute of TechnologyGreat progress has been made in reducing the cancer death toll through better prevention and screening, according to a new article by MIT Pro

Updated on:April 01,2024