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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Exploring the biology of 'double positive' T cells

Exploring the biology of 'double positive' T cells

byLudwig Cancer ResearchCredit: CC0 Public DomainThe molecular markers CD4 and CD8—defining helper T cells and killer T cells, respectively—were once considered mutually exclusive. But "dou

Exploring the biology of 'double positive' T cells

byLudwig Cancer ResearchCredit: CC0 Public DomainThe molecular markers CD4 and CD8—defining helper T cells and killer T cells, respectively—were once considered mutually exclusive. But "dou
Existing cancer drug ponatinib could be repurposed to fight certain aggressive cancers

Existing cancer drug ponatinib could be repurposed to fight certain aggressive cancers

byNanyang Technological UniversitySchematic summary of mechanisms of action of ponatinib in ALT cells. Ponatinib disrupts alternative lengthening of telomeres mechanisms by inducing telomeric C-

Existing cancer drug ponatinib could be repurposed to fight certain aggressive cancers

byNanyang Technological UniversitySchematic summary of mechanisms of action of ponatinib in ALT cells. Ponatinib disrupts alternative lengthening of telomeres mechanisms by inducing telomeric C-
Here's why some high-risk patients aren't getting drugs to combat COVID

Here's why some high-risk patients aren't getting drugs to combat COVID

by Emily Alpert Reyes, Los Angeles TimesCredit: Unsplash/CC0 Public DomainAs the toll from the COVID-19 pandemic continued to mount, antiviral medications such as Paxlovid were hailed by health offici

Here's why some high-risk patients aren't getting drugs to combat COVID

by Emily Alpert Reyes, Los Angeles TimesCredit: Unsplash/CC0 Public DomainAs the toll from the COVID-19 pandemic continued to mount, antiviral medications such as Paxlovid were hailed by health offici
CAR-T Therapy Under Scrutiny: The Emerging Risk of Secondary Malignant Tumors

CAR-T Therapy Under Scrutiny: The Emerging Risk of Secondary Malignant Tumors

CAR-T therapy has long been an effective treatment for hematological cancers such as leukemia and lymphoma. However, some patients have developed secondary malignant tumors after undergoing CAR-T ......

CAR-T Therapy Under Scrutiny: The Emerging Risk of Secondary Malignant Tumors

CAR-T therapy has long been an effective treatment for hematological cancers such as leukemia and lymphoma. However, some patients have developed secondary malignant tumors after undergoing CAR-T ......
A new therapeutic target turns the immune system against lymphoma

A new therapeutic target turns the immune system against lymphoma

by Ecole Polytechnique Federale de LausanneCredit: CC0 Public DomainNon-Hodgkin's lymphoma (NHL) is a group of cancers that originate in the lymph nodes and affect white blood cells of the im

A new therapeutic target turns the immune system against lymphoma

by Ecole Polytechnique Federale de LausanneCredit: CC0 Public DomainNon-Hodgkin's lymphoma (NHL) is a group of cancers that originate in the lymph nodes and affect white blood cells of the im
Cell therapy appears safe and effective for lymphoma in remission

Cell therapy appears safe and effective for lymphoma in remission

byUniversity of Miami Leonard M. Miller School of MedicineCredit: University of Miami Leonard M. Miller School of MedicineA study led by researchers at Sylvester Comprehensive Cancer Center at t

Cell therapy appears safe and effective for lymphoma in remission

byUniversity of Miami Leonard M. Miller School of MedicineCredit: University of Miami Leonard M. Miller School of MedicineA study led by researchers at Sylvester Comprehensive Cancer Center at t
How genetic therapies transformed the lives of sickle cell patients

How genetic therapies transformed the lives of sickle cell patients

Credit: CC0 Public DomainTheir stories are divided into before and after. First, those long years of pain which flooded every moment—school, relationships, work.And then—after agonizing treatments—wha

How genetic therapies transformed the lives of sickle cell patients

Credit: CC0 Public DomainTheir stories are divided into before and after. First, those long years of pain which flooded every moment—school, relationships, work.And then—after agonizing treatments—wha
Significant proportion of cancer drugs lack proof of added benefit, finds study

Significant proportion of cancer drugs lack proof of added benefit, finds study

by British Medical JournalCredit: CC0 Public DomainMany cancer drugs approved by the European Medicines Agency (EMA) between 1995 and 2020 lack proof of added benefit, particularly those approved

Significant proportion of cancer drugs lack proof of added benefit, finds study

by British Medical JournalCredit: CC0 Public DomainMany cancer drugs approved by the European Medicines Agency (EMA) between 1995 and 2020 lack proof of added benefit, particularly those approved
Race, income can determine blood cancer outcomes, studies show

Race, income can determine blood cancer outcomes, studies show

by Ernie MundellIf someone is stricken with a blood cancer or life-threatening clot, they'll probably fare better if they are white and wealthy, three new studies show.The ongoing impact of patien

Race, income can determine blood cancer outcomes, studies show

by Ernie MundellIf someone is stricken with a blood cancer or life-threatening clot, they'll probably fare better if they are white and wealthy, three new studies show.The ongoing impact of patien
Exploring mini-labs as an alternative to animal testing for evaluating radiopharmaceuticals

Exploring mini-labs as an alternative to animal testing for evaluating radiopharmaceuticals

byHelmholtz Association of German Research CentresMPS layout; red—media circuit with integrated pump; blue—pneumatic connectors; yellow—microwells for organoids; green—LUER-connectors). Credit:&

Exploring mini-labs as an alternative to animal testing for evaluating radiopharmaceuticals

byHelmholtz Association of German Research CentresMPS layout; red—media circuit with integrated pump; blue—pneumatic connectors; yellow—microwells for organoids; green—LUER-connectors). Credit:&
A treatment for metastasis? Using ferroptosis to attack migrating cancer cells

A treatment for metastasis? Using ferroptosis to attack migrating cancer cells

byFriedrich–Alexander University Erlangen–NurnbergZeb1 regulates the expression of enzymes crucial for adjusting the PUFA:MUFA ratio in phospholipids. Credit:Nature Cell Biology(2024

A treatment for metastasis? Using ferroptosis to attack migrating cancer cells

byFriedrich–Alexander University Erlangen–NurnbergZeb1 regulates the expression of enzymes crucial for adjusting the PUFA:MUFA ratio in phospholipids. Credit:Nature Cell Biology(2024
New treatment option for prostate cancer shows successful outcomes

New treatment option for prostate cancer shows successful outcomes

by The Reis GroupCredit: CC0 Public DomainA minimally-invasive treatment using MRI and transurethral ultrasound instead of surgery or radiation is effective in treating prostate cancer, according to n

New treatment option for prostate cancer shows successful outcomes

by The Reis GroupCredit: CC0 Public DomainA minimally-invasive treatment using MRI and transurethral ultrasound instead of surgery or radiation is effective in treating prostate cancer, according to n