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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Researchers build first large-scale atlas of how immune cells react to mutations during cancer immunotherapy

Researchers build first large-scale atlas of how immune cells react to mutations during cancer immunotherapy

byCleveland ClinicNeoantigen screening design and genomic features of NSCLC cohort.a, WES was performed onn= 58 pre-therapy samples andn= 42 on-therapy samples, whi

Researchers build first large-scale atlas of how immune cells react to mutations during cancer immunotherapy

byCleveland ClinicNeoantigen screening design and genomic features of NSCLC cohort.a, WES was performed onn= 58 pre-therapy samples andn= 42 on-therapy samples, whi
Early supper associated with lower risk of breast and prostate cancer

Early supper associated with lower risk of breast and prostate cancer

by Barcelona Institute for Global HealthEarly supper associated with breast and prostate cancer risk. Credit: ISGlobalHaving an early supper or leaving an interval of at least two hours before going t

Early supper associated with lower risk of breast and prostate cancer

by Barcelona Institute for Global HealthEarly supper associated with breast and prostate cancer risk. Credit: ISGlobalHaving an early supper or leaving an interval of at least two hours before going t
French Polynesia nuke tests slightly increased cancer risk: Study

French Polynesia nuke tests slightly increased cancer risk: Study

Underground nuclear tests in French Polynesia in 1985 have been a source of friction between Paris and the archipelago.Polynesians exposed to fallout from France's nuclear tests in the South Pacif

French Polynesia nuke tests slightly increased cancer risk: Study

Underground nuclear tests in French Polynesia in 1985 have been a source of friction between Paris and the archipelago.Polynesians exposed to fallout from France's nuclear tests in the South Pacif
Novobiocin attacks BRCA-mutated cancer cells from within and without, study shows

Novobiocin attacks BRCA-mutated cancer cells from within and without, study shows

byDana-Farber Cancer InstituteEfficacy of POLθ inhibition in HR-deficient cancers requires CD8+T cells.a,bK14-Cre-Brca1f/f;Trp53f/fTNBC tumors from syngeneic FVB/12

Novobiocin attacks BRCA-mutated cancer cells from within and without, study shows

byDana-Farber Cancer InstituteEfficacy of POLθ inhibition in HR-deficient cancers requires CD8+T cells.a,bK14-Cre-Brca1f/f;Trp53f/fTNBC tumors from syngeneic FVB/12
Protein linked to aggressive skin cancer

Protein linked to aggressive skin cancer

by Lund UniversityMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Almost 300,000 people worldwide develop malignan

Protein linked to aggressive skin cancer

by Lund UniversityMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Almost 300,000 people worldwide develop malignan
AI improving digestive cancer diagnosis, but data-sharing obstacles remain

AI improving digestive cancer diagnosis, but data-sharing obstacles remain

by Health Data ScienceThe AI analysis workflow in digestive system neoplasms. SVM, support vector machine; LASSO, the least absolute shrinkage and selection operator; LN, lymph node; ROC, receiver ope

AI improving digestive cancer diagnosis, but data-sharing obstacles remain

by Health Data ScienceThe AI analysis workflow in digestive system neoplasms. SVM, support vector machine; LASSO, the least absolute shrinkage and selection operator; LN, lymph node; ROC, receiver ope
Some breast cancer patients with high responses to chemotherapy may not need surgery

Some breast cancer patients with high responses to chemotherapy may not need surgery

by University of Texas M. D. Anderson Cancer CenterThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit:

Some breast cancer patients with high responses to chemotherapy may not need surgery

by University of Texas M. D. Anderson Cancer CenterThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit:
Study sends strong signal not to sequence immune checkpoint inhibitors in advanced kidney cancer

Study sends strong signal not to sequence immune checkpoint inhibitors in advanced kidney cancer

byDana-Farber Cancer InstituteCredit: Pixabay/CC0 Public DomainPatients with advanced kidney cancer are routinely given immune checkpoint inhibitors (ICIs) as first-line treatment. The CONTACT-0

Study sends strong signal not to sequence immune checkpoint inhibitors in advanced kidney cancer

byDana-Farber Cancer InstituteCredit: Pixabay/CC0 Public DomainPatients with advanced kidney cancer are routinely given immune checkpoint inhibitors (ICIs) as first-line treatment. The CONTACT-0
Fighting cancer one cell at a time

Fighting cancer one cell at a time

by Agency for Science, Technology and Research (A*STAR), SingaporeDrug-induced stem-cell switch (from Sox2 to Sox9) activates epigenetic re-programming driving tumour evolution in squamous cell c

Fighting cancer one cell at a time

by Agency for Science, Technology and Research (A*STAR), SingaporeDrug-induced stem-cell switch (from Sox2 to Sox9) activates epigenetic re-programming driving tumour evolution in squamous cell c
Study: Fat cells play key role in dangerous transformation of melanoma

Study: Fat cells play key role in dangerous transformation of melanoma

by Tel Aviv UniversityNano-vaccine mechanism of action: following injection, the nano-vaccine internalizes into immune cells, leading to activation of T cells to recognize and attack melanoma. Cr

Study: Fat cells play key role in dangerous transformation of melanoma

by Tel Aviv UniversityNano-vaccine mechanism of action: following injection, the nano-vaccine internalizes into immune cells, leading to activation of T cells to recognize and attack melanoma. Cr
First randomized phase 3 clinical trial of neoadjuvant immunotherapy in patients with kidney cancer

First randomized phase 3 clinical trial of neoadjuvant immunotherapy in patients with kidney cancer

by ECOG-ACRIN Cancer Research GroupCredit: Pixabay/CC0 Public DomainThe ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) will present data from PROSPER RCC (EA8143), the first randomized phase 3 trial of

First randomized phase 3 clinical trial of neoadjuvant immunotherapy in patients with kidney cancer

by ECOG-ACRIN Cancer Research GroupCredit: Pixabay/CC0 Public DomainThe ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) will present data from PROSPER RCC (EA8143), the first randomized phase 3 trial of