Peripheral blood haplo-SCT feasible for leukemia patients 70 years and older

by Elana GotkineFor patients with acute myeloid leukemia (AML)/myelodysplastic syndromes (MDS) aged 70 years and older, haploidentical stem cell transplantation (Haplo-SCT) using a nonmyeloablative co

Updated on: December 28,2023

Peripheral blood haplo-SCT feasible for leukemia patients 70 years and older

by Elana GotkineFor patients with acute myeloid leukemia (AML)/myelodysplastic syndromes (MDS) aged 70 years and older, haploidentical stem cell transplantation (Haplo-SCT) using a nonmyeloablative co

Updated on:December 28,2023

Disorderly DNA helps cancer cells evade treatment

byNorthwestern UniversityWhen the chromatin packing is heterogenous and disordered, a cell demonstrates more plasticity. Credit: Northwestern UniversityEach cell in the human body holds a full t

Updated on: December 22,2023

Disorderly DNA helps cancer cells evade treatment

byNorthwestern UniversityWhen the chromatin packing is heterogenous and disordered, a cell demonstrates more plasticity. Credit: Northwestern UniversityEach cell in the human body holds a full t

Updated on:December 22,2023

Unveiling the non-canonical functions of EZH2 in prostate cancer

by Impact Journals LLCProstate cancer cells. Credit: NIH Image GalleryA new editorial paper was published inOncotargettitled "Unveiling the non-canonical functions of EZH2 in prostate

Updated on: December 26,2023

Unveiling the non-canonical functions of EZH2 in prostate cancer

by Impact Journals LLCProstate cancer cells. Credit: NIH Image GalleryA new editorial paper was published inOncotargettitled "Unveiling the non-canonical functions of EZH2 in prostate

Updated on:December 26,2023

New therapeutic strategy for chemotherapy resistance in ovarian cancer

byThe Wistar InstituteDr. Rugang Zhang. Credit: The Wistar InstituteA study from The Wistar Institute demonstrated that NAMPT, an enzyme critical for NAD+ biosynthesis, mediates selection of ste

Updated on: December 22,2023

New therapeutic strategy for chemotherapy resistance in ovarian cancer

byThe Wistar InstituteDr. Rugang Zhang. Credit: The Wistar InstituteA study from The Wistar Institute demonstrated that NAMPT, an enzyme critical for NAD+ biosynthesis, mediates selection of ste

Updated on:December 22,2023

Revealing one of the mechanisms by which thyroid cancer becomes resistant to lenvatinib-a

by Shinshu UniversityThe EGFR-mediated pathway, which is not targeted by lenvatinib, is activated for survival in thyroid cancer cells under the potent inhibition of the VEGFR and FGFR families by len

Updated on: December 26,2023

Revealing one of the mechanisms by which thyroid cancer becomes resistant to lenvatinib-a

by Shinshu UniversityThe EGFR-mediated pathway, which is not targeted by lenvatinib, is activated for survival in thyroid cancer cells under the potent inhibition of the VEGFR and FGFR families by len

Updated on:December 26,2023

Study maps alterations that make melanoma more severe, could lead to better therapies and diagnosis

by André Julião,FAPESPStudy design, resources and methodology. A major aim (steps 1–2) is the discovery and validation of genome-wide methylation alterations associated with the UV mutational si

Updated on: February 20,2024

Study maps alterations that make melanoma more severe, could lead to better therapies and diagnosis

by André Julião,FAPESPStudy design, resources and methodology. A major aim (steps 1–2) is the discovery and validation of genome-wide methylation alterations associated with the UV mutational si

Updated on:February 20,2024

Study shows clinical benefit of a new way of treating advanced ER+ breast cancer

by University of LiverpoolCredit: Unsplash/CC0 Public DomainA research paper published today inThe Lancet Oncologydemonstrates that the drug enobosarm, a selective androgen receptor m

Updated on: May 26,2024

Study shows clinical benefit of a new way of treating advanced ER+ breast cancer

by University of LiverpoolCredit: Unsplash/CC0 Public DomainA research paper published today inThe Lancet Oncologydemonstrates that the drug enobosarm, a selective androgen receptor m

Updated on:May 26,2024

Fourth SARS-CoV-2 vaccination also protects cancer patients

by Johannes Angerer,Medical University of ViennaReceptor-Binding Domain and Angiotensin-Converting Enzyme 2 Interaction Inhibition in Patients With Hematologic Malignant Neoplasm With or Without

Updated on: December 20,2023

Fourth SARS-CoV-2 vaccination also protects cancer patients

by Johannes Angerer,Medical University of ViennaReceptor-Binding Domain and Angiotensin-Converting Enzyme 2 Interaction Inhibition in Patients With Hematologic Malignant Neoplasm With or Without

Updated on:December 20,2023

SABCS: Long-term outcomes good for PBI in early breast cancer

(HealthDay)—For patients with early-stage breast cancer, 10-year outcomes are similar for treatment with partial breast irradiation (PBI) and whole breast irradiation (WBI), according to a study prese

Updated on: December 22,2023

SABCS: Long-term outcomes good for PBI in early breast cancer

(HealthDay)—For patients with early-stage breast cancer, 10-year outcomes are similar for treatment with partial breast irradiation (PBI) and whole breast irradiation (WBI), according to a study prese

Updated on:December 22,2023

Surgery first for colon cancer? Not so fast, according to new study

by National Comprehensive Cancer NetworkRadiologic response, TRG, and clinical T stage. (A) Radiologic response among patients with different clinical T stage; patients with cT2–3 disease were more li

Updated on: January 10,2024

Surgery first for colon cancer? Not so fast, according to new study

by National Comprehensive Cancer NetworkRadiologic response, TRG, and clinical T stage. (A) Radiologic response among patients with different clinical T stage; patients with cT2–3 disease were more li

Updated on:January 10,2024

New drug combinations could improve therapies for breast cancer, other aggressive cancers

by Angela Yeager,Oregon Health & Science UniversityQuantification of CD8+T cells by multispectral flow cytometry in an ex vivo co-culture assay. Credit:Cell Reports Medicine&nbsp

Updated on: September 10,2024

New drug combinations could improve therapies for breast cancer, other aggressive cancers

by Angela Yeager,Oregon Health & Science UniversityQuantification of CD8+T cells by multispectral flow cytometry in an ex vivo co-culture assay. Credit:Cell Reports Medicine&nbsp

Updated on:September 10,2024

Exploring reasons for higher breast cancer risk among Caribbean women

by Sylvester Comprehensive Cancer CenterSylvester researcher Sophia George, Ph.D., who was raised in the Caribbean country of Dominica. Credit: Sylvester Comprehensive Cancer CenterA new study from re

Updated on: November 11,2024

Exploring reasons for higher breast cancer risk among Caribbean women

by Sylvester Comprehensive Cancer CenterSylvester researcher Sophia George, Ph.D., who was raised in the Caribbean country of Dominica. Credit: Sylvester Comprehensive Cancer CenterA new study from re

Updated on:November 11,2024