Novel late-stage colorectal cancer treatment proves effective in preclinical models

by Angel Mendez,University of Minnesota Medical SchoolThe low T cells are due to exosomal, immunosuppressive miRNAs that disrupt T cell function and loss of T cells in the tumor environment. Cre

Updated on: April 29,2024

Novel late-stage colorectal cancer treatment proves effective in preclinical models

by Angel Mendez,University of Minnesota Medical SchoolThe low T cells are due to exosomal, immunosuppressive miRNAs that disrupt T cell function and loss of T cells in the tumor environment. Cre

Updated on:April 29,2024

Exploring how gene mutations in tumors impact radiation sensitivity

byNorthwestern UniversityHigh-content irradiation platform reproducibility for the duration of the profiling effort. The signal-to-noise ratio (SNR), in blue represents the in-plate ratio of rad

Updated on: January 07,2024

Exploring how gene mutations in tumors impact radiation sensitivity

byNorthwestern UniversityHigh-content irradiation platform reproducibility for the duration of the profiling effort. The signal-to-noise ratio (SNR), in blue represents the in-plate ratio of rad

Updated on:January 07,2024

Dual checkpoint inhibitor blockade shows promise as first-line and salvage therapy for Merkel cell carcinoma patients

byH. Lee Moffitt Cancer Center & Research InstituteMicrograph of a lung primary small cell carcinoma, a type of carcinoma. Credit: WikipediaMerkel cell carcinoma is a rare but aggressive for

Updated on: January 04,2024

Dual checkpoint inhibitor blockade shows promise as first-line and salvage therapy for Merkel cell carcinoma patients

byH. Lee Moffitt Cancer Center & Research InstituteMicrograph of a lung primary small cell carcinoma, a type of carcinoma. Credit: WikipediaMerkel cell carcinoma is a rare but aggressive for

Updated on:January 04,2024

Tumor cells' response to chemotherapy is driven by randomness, shows study

byGarvan Institute of Medical ResearchNeuroblastoma cells (cyan) growing as a tumour and the surrounding collagen matrix (magenta). The cells are expressing a biosensor (JNK-KTR) that reads out

Updated on: January 23,2024

Tumor cells' response to chemotherapy is driven by randomness, shows study

byGarvan Institute of Medical ResearchNeuroblastoma cells (cyan) growing as a tumour and the surrounding collagen matrix (magenta). The cells are expressing a biosensor (JNK-KTR) that reads out

Updated on:January 23,2024

Study reveals mechanism linking heart disease to cancer development

byTel-Aviv UniversityCredit: CC0 Public DomainResearchers at Tel Aviv University (TAU) and the Leviev Cardiothoracic and Vascular Center at the Sheba Medical Center have found a mechanism respon

Updated on: April 28,2024

Study reveals mechanism linking heart disease to cancer development

byTel-Aviv UniversityCredit: CC0 Public DomainResearchers at Tel Aviv University (TAU) and the Leviev Cardiothoracic and Vascular Center at the Sheba Medical Center have found a mechanism respon

Updated on:April 28,2024

How oxygen deprivation causes cancer cells to spread

byLeiden UniversityCredit: Pixabay/CC0 Public DomainIn breast cancer, metastasis rather than the primary tumor is the cause of death. A lack of oxygen in the tumor cells promotes this metastasis

Updated on: January 02,2024

How oxygen deprivation causes cancer cells to spread

byLeiden UniversityCredit: Pixabay/CC0 Public DomainIn breast cancer, metastasis rather than the primary tumor is the cause of death. A lack of oxygen in the tumor cells promotes this metastasis

Updated on:January 02,2024

Time of day matters when it comes to cancer diagnosis and treatment, says metastasis study

byCell PressCredit: Unsplash/CC0 Public DomainYour circadian rhythm doesn't just govern your sleeping schedule; it can also impact cancer development, diagnosis, and treatment. In a review p

Updated on: January 23,2024

Time of day matters when it comes to cancer diagnosis and treatment, says metastasis study

byCell PressCredit: Unsplash/CC0 Public DomainYour circadian rhythm doesn't just govern your sleeping schedule; it can also impact cancer development, diagnosis, and treatment. In a review p

Updated on:January 23,2024

Right-sided colon cancer patients have poorer survival than those with left-sided disease

by American College of SurgeonsKiller T cells surround a cancer cell. Credit: NIHORLANDO (July 23, 2018): Patients with colorectal cancer tumors on the right side may have poorer five-year surviv

Updated on: May 07,2024

Right-sided colon cancer patients have poorer survival than those with left-sided disease

by American College of SurgeonsKiller T cells surround a cancer cell. Credit: NIHORLANDO (July 23, 2018): Patients with colorectal cancer tumors on the right side may have poorer five-year surviv

Updated on:May 07,2024

Cancer metastasis: Tumor plasticity counts

by Université libre de BruxellesCredit: CC0 Public DomainCancer metastasis, which is the propagation of tumor cells into distant organs, is the leading cause of cancer patient mortality. To under

Updated on: March 12,2024

Cancer metastasis: Tumor plasticity counts

by Université libre de BruxellesCredit: CC0 Public DomainCancer metastasis, which is the propagation of tumor cells into distant organs, is the leading cause of cancer patient mortality. To under

Updated on:March 12,2024

Possible therapeutic approach to fight incurable blood cancer

by Technical University MunichGraphical abstract. Credit:The EMBO Journal(2022). DOI: 10.15252/embj.2022110871Multiple myeloma (MM) is the second most common type of blood cancer. It

Updated on: January 30,2024

Possible therapeutic approach to fight incurable blood cancer

by Technical University MunichGraphical abstract. Credit:The EMBO Journal(2022). DOI: 10.15252/embj.2022110871Multiple myeloma (MM) is the second most common type of blood cancer. It

Updated on:January 30,2024

Renal impairment linked to worse prognosis in IgD multiple myeloma

by Elana GotkineFor patients with immunoglobulin D multiple myeloma (IgD MM), those with renal impairment (RI) have poorer prognosis and shorter median survival than those with no renal impairment (no

Updated on: January 04,2024

Renal impairment linked to worse prognosis in IgD multiple myeloma

by Elana GotkineFor patients with immunoglobulin D multiple myeloma (IgD MM), those with renal impairment (RI) have poorer prognosis and shorter median survival than those with no renal impairment (no

Updated on:January 04,2024

Study highlights difficulty in diagnosing blood disorders, need for coordination between clinicians and pathologists

by University of Miami Leonard M. Miller School of Medicine“Our findings highlight the vital importance of seeking expert opinions from National Cancer Institute-designated cancer centers, especi

Updated on: January 30,2024

Study highlights difficulty in diagnosing blood disorders, need for coordination between clinicians and pathologists

by University of Miami Leonard M. Miller School of Medicine“Our findings highlight the vital importance of seeking expert opinions from National Cancer Institute-designated cancer centers, especi

Updated on:January 30,2024