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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Childhood cancer deaths in the United States have declined six-fold over the last seventy years

Childhood cancer deaths in the United States have declined six-fold over the last seventy years

Childhood cancer deaths in the United States have fallen dramatically over time, as shown in the chart. It presents annual cancer death rates in children under five years old.

Childhood cancer deaths in the United States have declined six-fold over the last seventy years

Childhood cancer deaths in the United States have fallen dramatically over time, as shown in the chart. It presents annual cancer death rates in children under five years old.
Predicting DCIS upgrade to invasive cancer at breast surgery with ultrafast imaging

Predicting DCIS upgrade to invasive cancer at breast surgery with ultrafast imaging

by American Roentgen Ray SocietyA) Preoperative breast MRI, initial DCE post-contrast axial fat-saturated T1 axial subtraction image, demonstrates 6 cm clumped enhancement surrounding biopsy clip

Predicting DCIS upgrade to invasive cancer at breast surgery with ultrafast imaging

by American Roentgen Ray SocietyA) Preoperative breast MRI, initial DCE post-contrast axial fat-saturated T1 axial subtraction image, demonstrates 6 cm clumped enhancement surrounding biopsy clip
New hormone therapies before surgery may improve outcomes in high-risk prostate cancer

New hormone therapies before surgery may improve outcomes in high-risk prostate cancer

byWolters Kluwer HealthTime to BCR in the neo-RP and RP cohorts after IPTW. The number of participants at risk are based on unweighted population. Credit:Journal of Urology(2022). DO

New hormone therapies before surgery may improve outcomes in high-risk prostate cancer

byWolters Kluwer HealthTime to BCR in the neo-RP and RP cohorts after IPTW. The number of participants at risk are based on unweighted population. Credit:Journal of Urology(2022). DO
Gene and cell therapies to combat pancreatic cancer

Gene and cell therapies to combat pancreatic cancer

byMary Ann Liebert, IncGTMP clinical trials for pancreatic cancer depending on phase and trial status. Source: Clinical trial.gov. GTMPs, gene therapy medicinal products. Credit:Human Gene

Gene and cell therapies to combat pancreatic cancer

byMary Ann Liebert, IncGTMP clinical trials for pancreatic cancer depending on phase and trial status. Source: Clinical trial.gov. GTMPs, gene therapy medicinal products. Credit:Human Gene
Combining neurologic and blood pressure drugs reduces breast tumor development in mice

Combining neurologic and blood pressure drugs reduces breast tumor development in mice

byGeorgetown University Medical CenterCancer cell during cell division. Credit: National Institutes of HealthAdding a medication used to treat epilepsy, bipolar disorder and migraines to a blood

Combining neurologic and blood pressure drugs reduces breast tumor development in mice

byGeorgetown University Medical CenterCancer cell during cell division. Credit: National Institutes of HealthAdding a medication used to treat epilepsy, bipolar disorder and migraines to a blood
Training the immune system to prevent cancer—researchers discover paradigm-shifting approach

Training the immune system to prevent cancer—researchers discover paradigm-shifting approach

by Courtney Perrett,University of MissouriSA-4-1BBL treatment protected mice from developing lung tumors induced by NNK.AExperimental design, and treatment timeline.Female A/J

Training the immune system to prevent cancer—researchers discover paradigm-shifting approach

by Courtney Perrett,University of MissouriSA-4-1BBL treatment protected mice from developing lung tumors induced by NNK.AExperimental design, and treatment timeline.Female A/J
Discovery could improve MDS cancer treatment

Discovery could improve MDS cancer treatment

by Cold Spring Harbor LaboratoryImmature blood cells (stained purple) do not divide into enough functioning red blood cells when defective. Researchers have discovered how to stop the protein sig

Discovery could improve MDS cancer treatment

by Cold Spring Harbor LaboratoryImmature blood cells (stained purple) do not divide into enough functioning red blood cells when defective. Researchers have discovered how to stop the protein sig
How two 1990s discoveries have led to (some) cured cancers, and a Nobel Prize

How two 1990s discoveries have led to (some) cured cancers, and a Nobel Prize

by Craig Gedye,The ConversationCredit: CC0 Public DomainThis year's award of theNobel Prize for Physiology and Medicineto James P. Allison and Tasuku Honjo, for their work in the

How two 1990s discoveries have led to (some) cured cancers, and a Nobel Prize

by Craig Gedye,The ConversationCredit: CC0 Public DomainThis year's award of theNobel Prize for Physiology and Medicineto James P. Allison and Tasuku Honjo, for their work in the
Going for a walk wasn't really a thing 300 years ago—the Victorians turned it into a popular pastime

Going for a walk wasn't really a thing 300 years ago—the Victorians turned it into a popular pastime

by Lauren Nichola Colley,The ConversationCredit: Pixabay/CC0 Public DomainGoing for a walk is always a good idea. Perhaps, if you are lucky enough, this might be a hike along ragged cliffs or tr

Going for a walk wasn't really a thing 300 years ago—the Victorians turned it into a popular pastime

by Lauren Nichola Colley,The ConversationCredit: Pixabay/CC0 Public DomainGoing for a walk is always a good idea. Perhaps, if you are lucky enough, this might be a hike along ragged cliffs or tr
Researchers identify protein with DYRK1A-inhibiting effect that may have implications for Down syndrome

Researchers identify protein with DYRK1A-inhibiting effect that may have implications for Down syndrome

by Kyoto UniversityDYRK1A bound to FAM53C in the cytoplasm is less active. DYRK1A not bound to FAM53C in the nucleus is highly active. Functional abnormalities cause various neuropsychiatric deve

Researchers identify protein with DYRK1A-inhibiting effect that may have implications for Down syndrome

by Kyoto UniversityDYRK1A bound to FAM53C in the cytoplasm is less active. DYRK1A not bound to FAM53C in the nucleus is highly active. Functional abnormalities cause various neuropsychiatric deve
Risk model identifies metastatic cancer patients who may benefit from immune checkpoint inhibitors

Risk model identifies metastatic cancer patients who may benefit from immune checkpoint inhibitors

byUniversity of Eastern FinlandSurvival of the patients according to the risk scores. Kaplan-Meier curves illustrating overall survival (OS) (a) and progression-free survival (PFS) (b) according

Risk model identifies metastatic cancer patients who may benefit from immune checkpoint inhibitors

byUniversity of Eastern FinlandSurvival of the patients according to the risk scores. Kaplan-Meier curves illustrating overall survival (OS) (a) and progression-free survival (PFS) (b) according
Surgery first for colon cancer? Not so fast, according to new study

Surgery first for colon cancer? Not so fast, according to new study

by National Comprehensive Cancer NetworkRadiologic response, TRG, and clinical T stage. (A) Radiologic response among patients with different clinical T stage; patients with cT2–3 disease were more li

Surgery first for colon cancer? Not so fast, according to new study

by National Comprehensive Cancer NetworkRadiologic response, TRG, and clinical T stage. (A) Radiologic response among patients with different clinical T stage; patients with cT2–3 disease were more li