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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
Sub Categories on Oncology
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Some cancer immunotherapy treatments may damage fertility

Some cancer immunotherapy treatments may damage fertility

by Monash UniversityCredit: Pixabay/CC0 Public DomainResearchers have discovered that some immunotherapy treatments used to treat cancer can cause fertility damage.It means these treatments could

Some cancer immunotherapy treatments may damage fertility

by Monash UniversityCredit: Pixabay/CC0 Public DomainResearchers have discovered that some immunotherapy treatments used to treat cancer can cause fertility damage.It means these treatments could
New research reviews myeloid-derived suppressor cells in cancer, autoimmune diseases, and more

New research reviews myeloid-derived suppressor cells in cancer, autoimmune diseases, and more

by Impact Journals LLCMDSCs generated by obesity migrate to lymphoid organ and TME. Credit: 2022 Shibata et al.A new review titled "Myeloid-derived suppressor cells: Cancer, autoimmune diseases,

New research reviews myeloid-derived suppressor cells in cancer, autoimmune diseases, and more

by Impact Journals LLCMDSCs generated by obesity migrate to lymphoid organ and TME. Credit: 2022 Shibata et al.A new review titled "Myeloid-derived suppressor cells: Cancer, autoimmune diseases,
Tumor-induced B cell changes reveal potential biomarker for treatment response in triple negative breast cancer

Tumor-induced B cell changes reveal potential biomarker for treatment response in triple negative breast cancer

byBaylor College of MedicineCredit: Pixabay/CC0 Public DomainResearchers at Baylor College of Medicine and collaborating institutions have discovered new insights into tumor-induced B cell chang

Tumor-induced B cell changes reveal potential biomarker for treatment response in triple negative breast cancer

byBaylor College of MedicineCredit: Pixabay/CC0 Public DomainResearchers at Baylor College of Medicine and collaborating institutions have discovered new insights into tumor-induced B cell chang
Skin cancer rewires its energy systems to spread more efficiently, finds study

Skin cancer rewires its energy systems to spread more efficiently, finds study

by Queen Mary, University of LondonDifferent modes of migration and mitochondrial metabolism.a,bOxygen consumption rate (OCR) from cells embedded in a 3D collagen I matrix (n = 

Skin cancer rewires its energy systems to spread more efficiently, finds study

by Queen Mary, University of LondonDifferent modes of migration and mitochondrial metabolism.a,bOxygen consumption rate (OCR) from cells embedded in a 3D collagen I matrix (n = 
Researchers identify mechanism of resistance to BRAF inhibitors in melanoma

Researchers identify mechanism of resistance to BRAF inhibitors in melanoma

by H. Lee Moffitt Cancer Center & Research InstituteMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Melanoma i

Researchers identify mechanism of resistance to BRAF inhibitors in melanoma

by H. Lee Moffitt Cancer Center & Research InstituteMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Melanoma i
Killing pancreatic cancer with T cells that supercharge themselves

Killing pancreatic cancer with T cells that supercharge themselves

by University of California, San FranciscoTherapeutic T cells engineered with tumor-triggered IL-2 production infiltrate and clear immune-excluded tumors. (A) We hypothesized that cell autonomous

Killing pancreatic cancer with T cells that supercharge themselves

by University of California, San FranciscoTherapeutic T cells engineered with tumor-triggered IL-2 production infiltrate and clear immune-excluded tumors. (A) We hypothesized that cell autonomous
Preclinical study shows promise of systemic targeted therapy in a rare form of cancer

Preclinical study shows promise of systemic targeted therapy in a rare form of cancer

byVall d'Hebron Institute of OncologyTreatment with BRAF inhibitors reduces tumor cell proliferation in subcutaneous BRAFV600EPMP-PDX tumors without impacting in apoptosis. a–d) Mice b

Preclinical study shows promise of systemic targeted therapy in a rare form of cancer

byVall d'Hebron Institute of OncologyTreatment with BRAF inhibitors reduces tumor cell proliferation in subcutaneous BRAFV600EPMP-PDX tumors without impacting in apoptosis. a–d) Mice b
DDX41 and its unique contribution to myeloid leukemogenesis

DDX41 and its unique contribution to myeloid leukemogenesis

by Impact Journals LLCCredit: Unsplash/CC0 Public DomainIn an editorial paper published inOncotargettitled, "DDX41 and its unique contribution to myeloid leukemogenesis," researc

DDX41 and its unique contribution to myeloid leukemogenesis

by Impact Journals LLCCredit: Unsplash/CC0 Public DomainIn an editorial paper published inOncotargettitled, "DDX41 and its unique contribution to myeloid leukemogenesis," researc
Study shows novel agent can overcome immune dysfunction in cancer

Study shows novel agent can overcome immune dysfunction in cancer

by Roswell Park Comprehensive Cancer CenterVSSP restores myeloid cell frequencies following leukopenia. C57BL/6 mice were injected with CY (200 mg/kg body weight, i.p.) and with two consecutive daily

Study shows novel agent can overcome immune dysfunction in cancer

by Roswell Park Comprehensive Cancer CenterVSSP restores myeloid cell frequencies following leukopenia. C57BL/6 mice were injected with CY (200 mg/kg body weight, i.p.) and with two consecutive daily
The sugar-attaching enzyme that defines colon cancer

The sugar-attaching enzyme that defines colon cancer

by American Society for Biochemistry and Molecular BiologyThe enzyme GalNAc-T6 is selectively up-regulated in colon adenocarcinomas, and its expression is associated with a cancer-like growth pat

The sugar-attaching enzyme that defines colon cancer

by American Society for Biochemistry and Molecular BiologyThe enzyme GalNAc-T6 is selectively up-regulated in colon adenocarcinomas, and its expression is associated with a cancer-like growth pat
Study: Drugs reprogram genes in breast tumors to prevent endocrine resistance

Study: Drugs reprogram genes in breast tumors to prevent endocrine resistance

by Sharita Forrest,University of Illinois at Urbana-ChampaignTargeting estrogen receptor-positive breast tumors with the XPO1 antagonist selinexor and the tamoxifen byproduct 4-OHT simultaneousl

Study: Drugs reprogram genes in breast tumors to prevent endocrine resistance

by Sharita Forrest,University of Illinois at Urbana-ChampaignTargeting estrogen receptor-positive breast tumors with the XPO1 antagonist selinexor and the tamoxifen byproduct 4-OHT simultaneousl
Researchers to investigate screening for prostate cancer using MRI—potentially replacing the PSA test

Researchers to investigate screening for prostate cancer using MRI—potentially replacing the PSA test

by Medical Research CouncilCredit: Medical Research CouncilA new clinical study will test for the first time if MRI scans can be used for population screening to detect prostate cancer more accur

Researchers to investigate screening for prostate cancer using MRI—potentially replacing the PSA test

by Medical Research CouncilCredit: Medical Research CouncilA new clinical study will test for the first time if MRI scans can be used for population screening to detect prostate cancer more accur