Liquid biopsies reveal genetic alterations linked to cancer drug resistance

by Nicole Davis,Broad Institute of MIT and HarvardCredit: CC0 Public DomainMany patients see their tumors shrink in response to a drug, only to have them come back with a vengeance as they evolv

Updated on: May 23,2024

Liquid biopsies reveal genetic alterations linked to cancer drug resistance

by Nicole Davis,Broad Institute of MIT and HarvardCredit: CC0 Public DomainMany patients see their tumors shrink in response to a drug, only to have them come back with a vengeance as they evolv

Updated on:May 23,2024

The protein behind immunotherapy resistance

byEcole Polytechnique Federale de LausanneTumor with FMRP-deficient cancer cells (in green) being infiltrated and attached by killer (CD8) T cells. Credit: Jeremy Guillot (Hanahan Lab – EPFL).Im

Updated on: January 02,2024

The protein behind immunotherapy resistance

byEcole Polytechnique Federale de LausanneTumor with FMRP-deficient cancer cells (in green) being infiltrated and attached by killer (CD8) T cells. Credit: Jeremy Guillot (Hanahan Lab – EPFL).Im

Updated on:January 02,2024

Novel genomics tool enables more accurate identification of rare mutations in cancer cells

by New York Genome CenterExample of colored de Bruijn graph rendered to represent genomic data for a short region of 400 base pairs using the Lancet genomics tool developed by New York Genome Center s

Updated on: March 01,2024

Novel genomics tool enables more accurate identification of rare mutations in cancer cells

by New York Genome CenterExample of colored de Bruijn graph rendered to represent genomic data for a short region of 400 base pairs using the Lancet genomics tool developed by New York Genome Center s

Updated on:March 01,2024

Study: Drugs reprogram genes in breast tumors to prevent endocrine resistance

by Sharita Forrest,University of Illinois at Urbana-ChampaignTargeting estrogen receptor-positive breast tumors with the XPO1 antagonist selinexor and the tamoxifen byproduct 4-OHT simultaneousl

Updated on: May 27,2024

Study: Drugs reprogram genes in breast tumors to prevent endocrine resistance

by Sharita Forrest,University of Illinois at Urbana-ChampaignTargeting estrogen receptor-positive breast tumors with the XPO1 antagonist selinexor and the tamoxifen byproduct 4-OHT simultaneousl

Updated on:May 27,2024

Can diet help cancer treatment? Study in mice offers clues

by Sara HusseinA study in the journalNaturefound that restricting the intake of an amino acid found in red meat and eggs slowed the growth of cancerous tumours in miceDiet is already a key

Updated on: May 11,2024

Can diet help cancer treatment? Study in mice offers clues

by Sara HusseinA study in the journalNaturefound that restricting the intake of an amino acid found in red meat and eggs slowed the growth of cancerous tumours in miceDiet is already a key

Updated on:May 11,2024

Deep learning algorithm may streamline lung cancer radiotherapy treatment

byBrigham and Women's HospitalCredit: Unsplash/CC0 Public DomainLung cancer, the most common cancer worldwide, is targeted with radiation therapy (RT) in nearly one-half of cases. RT plannin

Updated on: January 04,2024

Deep learning algorithm may streamline lung cancer radiotherapy treatment

byBrigham and Women's HospitalCredit: Unsplash/CC0 Public DomainLung cancer, the most common cancer worldwide, is targeted with radiation therapy (RT) in nearly one-half of cases. RT plannin

Updated on:January 04,2024

New study shows recently diagnosed adult cancer survivors at higher risk for bone fractures

byAmerican Cancer SocietyAdult cancer survivors at increased risk for bone fractures. Credit: American Cancer SocietyAdult cancer survivors, particularly those diagnosed within five years and/or

Updated on: January 12,2024

New study shows recently diagnosed adult cancer survivors at higher risk for bone fractures

byAmerican Cancer SocietyAdult cancer survivors at increased risk for bone fractures. Credit: American Cancer SocietyAdult cancer survivors, particularly those diagnosed within five years and/or

Updated on:January 12,2024

BMI's relation to cancer therapy mortality risks not so straightforward, study finds

byOsaka Metropolitan UniversityFor non-small cell lung cancer treatment, immunotherapy seems to pose less risk for persons under a certain BMI, while conventional chemotherapy appears optimal fo

Updated on: September 27,2024

BMI's relation to cancer therapy mortality risks not so straightforward, study finds

byOsaka Metropolitan UniversityFor non-small cell lung cancer treatment, immunotherapy seems to pose less risk for persons under a certain BMI, while conventional chemotherapy appears optimal fo

Updated on:September 27,2024

Research identifies new target that may prevent blood cancer

by Bill Snyder,Vanderbilt University Medical CenterCredit: Unsplash/CC0 Public DomainAn international coalition of biomedical researchers co-led by Alexander Bick, MD, Ph.D., at Vanderbilt Unive

Updated on: February 18,2024

Research identifies new target that may prevent blood cancer

by Bill Snyder,Vanderbilt University Medical CenterCredit: Unsplash/CC0 Public DomainAn international coalition of biomedical researchers co-led by Alexander Bick, MD, Ph.D., at Vanderbilt Unive

Updated on:February 18,2024

Cis-regulatory sequences indicative of nasopharyngeal carcinoma risk identified

by Justin Jackson , Medical XpressCredit:The American Journal of Human Genetics(2023). DOI: 10.1016/j.ajhg.2023.06.003Research led by the Sun Yat-sen University Cancer Center in China has

Updated on: February 01,2024

Cis-regulatory sequences indicative of nasopharyngeal carcinoma risk identified

by Justin Jackson , Medical XpressCredit:The American Journal of Human Genetics(2023). DOI: 10.1016/j.ajhg.2023.06.003Research led by the Sun Yat-sen University Cancer Center in China has

Updated on:February 01,2024

Inhibition of histone deacetylase 2 reduces MDM2 expression and reduces tumor growth in dedifferentiated liposarcoma

by OncotargetElevated HDAC2 mRNA expression is poorly prognostic in DDLPS. (A) mRNA expression of HDAC2 and disease-free survival (DFS) data from 52 subjects with DDLPS from The Cancer Genome Atlas (T

Updated on: May 11,2024

Inhibition of histone deacetylase 2 reduces MDM2 expression and reduces tumor growth in dedifferentiated liposarcoma

by OncotargetElevated HDAC2 mRNA expression is poorly prognostic in DDLPS. (A) mRNA expression of HDAC2 and disease-free survival (DFS) data from 52 subjects with DDLPS from The Cancer Genome Atlas (T

Updated on:May 11,2024

Researchers determine epigenetic origin of docetaxel-resistant breast cancer

by IDIBELL-Bellvitge Biomedical Research InstituteResearchers at the Bellvitge Biomedical Research Institute (IDIBELL), published today in Molecular Cancer Research a study where they identify me

Updated on: June 08,2024

Researchers determine epigenetic origin of docetaxel-resistant breast cancer

by IDIBELL-Bellvitge Biomedical Research InstituteResearchers at the Bellvitge Biomedical Research Institute (IDIBELL), published today in Molecular Cancer Research a study where they identify me

Updated on:June 08,2024