Researchers identify key metabolic regulators of drug resistance in the fight against pancreatic cancer

by Rebecca Brierley,University at BuffaloGraphical abstract. Credit:Molecular & Cellular Proteomics(2022). DOI: 10.1016/j.mcpro.2022.100409Researchers from the University at Buff

Updated on: February 20,2024

Researchers identify key metabolic regulators of drug resistance in the fight against pancreatic cancer

by Rebecca Brierley,University at BuffaloGraphical abstract. Credit:Molecular & Cellular Proteomics(2022). DOI: 10.1016/j.mcpro.2022.100409Researchers from the University at Buff

Updated on:February 20,2024

Research identifies a new drug candidate to starve and suffocate breast cancer cell stem growth

by University of SalfordMichael P. Lisanti. Credit: University of SalfordScientists have identified a new drug candidate that is able starve and suffocate cancer stem cells, paving the way for ne

Updated on: June 28,2024

Research identifies a new drug candidate to starve and suffocate breast cancer cell stem growth

by University of SalfordMichael P. Lisanti. Credit: University of SalfordScientists have identified a new drug candidate that is able starve and suffocate cancer stem cells, paving the way for ne

Updated on:June 28,2024

Researchers create new tool for assessing risk of kidney injury after chemotherapy

by Brigham and Women’s HospitalCredit: Pixabay/CC0 Public DomainUsing patient data from six major U.S. cancer centers, Brigham researchers and collaborators developed a risk prediction model for

Updated on: March 30,2024

Researchers create new tool for assessing risk of kidney injury after chemotherapy

by Brigham and Women’s HospitalCredit: Pixabay/CC0 Public DomainUsing patient data from six major U.S. cancer centers, Brigham researchers and collaborators developed a risk prediction model for

Updated on:March 30,2024

An unexpected journey reveals a potent way to attack tumors

by Nancy Fliesler,Children's Hospital BostonSenescence inducer CuSO4, which causes ER stress, activates NKp46- and NKG2D-dependent NK killing, but 4-PBA, which induces senescence without ER

Updated on: February 23,2024

An unexpected journey reveals a potent way to attack tumors

by Nancy Fliesler,Children's Hospital BostonSenescence inducer CuSO4, which causes ER stress, activates NKp46- and NKG2D-dependent NK killing, but 4-PBA, which induces senescence without ER

Updated on:February 23,2024

70-gene signature impacts treatment decisions in breast CA

(HealthDay)—The 70-gene signature (GS) assay affects treatment decisions among physicians treating patients identified as being at intermediate risk with the 21-gene assay (21-GA), according to a stud

Updated on: March 14,2024

70-gene signature impacts treatment decisions in breast CA

(HealthDay)—The 70-gene signature (GS) assay affects treatment decisions among physicians treating patients identified as being at intermediate risk with the 21-gene assay (21-GA), according to a stud

Updated on:March 14,2024

Loss of Y chromosome in men enables cancer to grow, finds new study

by Cedars-Sinai Medical CenterCredit: Pixabay/CC0 Public DomainAs men age, some of their cells lose the very thing that makes them biological males—the Y chromosome—and this loss hampers the body

Updated on: January 30,2024

Loss of Y chromosome in men enables cancer to grow, finds new study

by Cedars-Sinai Medical CenterCredit: Pixabay/CC0 Public DomainAs men age, some of their cells lose the very thing that makes them biological males—the Y chromosome—and this loss hampers the body

Updated on:January 30,2024

Diverse immune cell profiles and roles found in breast cancer resistance to immunotherapy

by Baylor College of MedicineDr. Xiang 'Shawn' Zhang, the corresponding author of this work. Credit: Baylor College of MedicineIn recent years it has been increasingly appreciated that im

Updated on: April 22,2024

Diverse immune cell profiles and roles found in breast cancer resistance to immunotherapy

by Baylor College of MedicineDr. Xiang 'Shawn' Zhang, the corresponding author of this work. Credit: Baylor College of MedicineIn recent years it has been increasingly appreciated that im

Updated on:April 22,2024

Allogeneic hematopoietic cell transplant outcomes improved from 2005 to 2019: Study

by Lori SolomonOutcomes of allogeneic hematopoietic cell transplantation (allo-HCT) in patients with acute myeloid leukemia (AML) and second complete remission (CR2) have significantly improved over t

Updated on: February 18,2024

Allogeneic hematopoietic cell transplant outcomes improved from 2005 to 2019: Study

by Lori SolomonOutcomes of allogeneic hematopoietic cell transplantation (allo-HCT) in patients with acute myeloid leukemia (AML) and second complete remission (CR2) have significantly improved over t

Updated on:February 18,2024

Immunotherapy was meant to defeat cancer—what happened to the great promise?

by Jonathan Fisher,The ConversationCredit: Ivan Samkov from PexelsIn 1893, theAmerican Journal of the Medical Sciencesreported on 10 patients whose large and hitherto incurable cance

Updated on: November 10,2024

Immunotherapy was meant to defeat cancer—what happened to the great promise?

by Jonathan Fisher,The ConversationCredit: Ivan Samkov from PexelsIn 1893, theAmerican Journal of the Medical Sciencesreported on 10 patients whose large and hitherto incurable cance

Updated on:November 10,2024

Researchers discover method to 'turn off' mutated melanoma

by Boston University School of MedicineMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Melanoma is the deadliest f

Updated on: June 22,2024

Researchers discover method to 'turn off' mutated melanoma

by Boston University School of MedicineMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Melanoma is the deadliest f

Updated on:June 22,2024

Researchers determine epigenetic origin of docetaxel-resistant breast cancer

by IDIBELL-Bellvitge Biomedical Research InstituteResearchers at the Bellvitge Biomedical Research Institute (IDIBELL), published today in Molecular Cancer Research a study where they identify me

Updated on: June 08,2024

Researchers determine epigenetic origin of docetaxel-resistant breast cancer

by IDIBELL-Bellvitge Biomedical Research InstituteResearchers at the Bellvitge Biomedical Research Institute (IDIBELL), published today in Molecular Cancer Research a study where they identify me

Updated on:June 08,2024

A machine learning-based algorithm to predict which cancer patients benefit from immunotherapy

by Institute for Research in Biomedicine (IRB Barcelona)Credit: CC0 Public DomainScientists at the Institute for Research in Biomedicine (IRB Barcelona), in collaboration with the Centre for Geno

Updated on: May 20,2024

A machine learning-based algorithm to predict which cancer patients benefit from immunotherapy

by Institute for Research in Biomedicine (IRB Barcelona)Credit: CC0 Public DomainScientists at the Institute for Research in Biomedicine (IRB Barcelona), in collaboration with the Centre for Geno

Updated on:May 20,2024