Study validates clinical utility of pan-tumor predictive biomarker for checkpoint inhibitor immunotherapy benefit

by Strata OncologyDevelopment of an integrative immunotherapy response score (IRS) model to stratify PD-(L)1 therapy benefit in patients with advanced solid tumors.aReal-world treatment an

Updated on: February 03,2024

Study validates clinical utility of pan-tumor predictive biomarker for checkpoint inhibitor immunotherapy benefit

by Strata OncologyDevelopment of an integrative immunotherapy response score (IRS) model to stratify PD-(L)1 therapy benefit in patients with advanced solid tumors.aReal-world treatment an

Updated on:February 03,2024

by Niigata UniversityCredit: Unsplash/CC0 Public DomainAn international team led by the Department of Neurosurgery, Niigata University, has identified a new gene called Schlafen11 (SLFN11) whose expre

Updated on: February 03,2024

by Niigata UniversityCredit: Unsplash/CC0 Public DomainAn international team led by the Department of Neurosurgery, Niigata University, has identified a new gene called Schlafen11 (SLFN11) whose expre

Updated on:February 03,2024

Leukemia spread fueled by messenger particles, shows study

byKing Abdullah University of Science and TechnologyMass spectrometry analysis reveals HSPCs-derived exosomes are enriched in proteins involved in adhesion and migration. Proteomics analysis of

Updated on: January 16,2024

Leukemia spread fueled by messenger particles, shows study

byKing Abdullah University of Science and TechnologyMass spectrometry analysis reveals HSPCs-derived exosomes are enriched in proteins involved in adhesion and migration. Proteomics analysis of

Updated on:January 16,2024

New method eradicates deadly brain tumors by 'starving' them of energy source

byTel Aviv UniversityDr. Lior Mayo and students. Credit: Tel Aviv UniversityA groundbreaking study at Tel Aviv University effectively eradicated glioblastoma, a highly lethal type of brain cance

Updated on: January 13,2024

New method eradicates deadly brain tumors by 'starving' them of energy source

byTel Aviv UniversityDr. Lior Mayo and students. Credit: Tel Aviv UniversityA groundbreaking study at Tel Aviv University effectively eradicated glioblastoma, a highly lethal type of brain cance

Updated on:January 13,2024

Ancient viruses could help kill cancers

by The Francis Crick InstituteHeatmap showing expression of melanoma-specific transcripts across a range of cancer types. The three columns with high expression are from melanoma samples. Credit:

Updated on: March 30,2024

Ancient viruses could help kill cancers

by The Francis Crick InstituteHeatmap showing expression of melanoma-specific transcripts across a range of cancer types. The three columns with high expression are from melanoma samples. Credit:

Updated on:March 30,2024

Synthetic molecule proves able to mitigate heart failure in translational study

by Maria Fernanda Ziegler,FAPESPThe vicious cycle of heart failure (HF). (i) Impaired aldehyde metabolism by aldehyde dehydrogenase 2 (ALDH2); (ii) accumulation of 4-hydroxynonenal (4-HNE), a re

Updated on: April 01,2024

Synthetic molecule proves able to mitigate heart failure in translational study

by Maria Fernanda Ziegler,FAPESPThe vicious cycle of heart failure (HF). (i) Impaired aldehyde metabolism by aldehyde dehydrogenase 2 (ALDH2); (ii) accumulation of 4-hydroxynonenal (4-HNE), a re

Updated on:April 01,2024

Previously unidentified proteins suggest new way to diagnose ovarian cancer

by Nagoya UniversityExtracellular vesicles (EVs) are vesicles with lipid-bilayer structures (shown in center), and three proteins expressed on small EVs called exosomes (shown in red, green, blue

Updated on: February 23,2024

Previously unidentified proteins suggest new way to diagnose ovarian cancer

by Nagoya UniversityExtracellular vesicles (EVs) are vesicles with lipid-bilayer structures (shown in center), and three proteins expressed on small EVs called exosomes (shown in red, green, blue

Updated on:February 23,2024

Revealing characteristics of circulating cell-free RNA in the blood of liver cancer patients

byScience China PressMOF materials efficiently enrich circulating nucleic acids (cfDNA and cfRNA) in blood through a simple operational process, enabling various downstream nucleic acid detectio

Updated on: March 30,2024

Revealing characteristics of circulating cell-free RNA in the blood of liver cancer patients

byScience China PressMOF materials efficiently enrich circulating nucleic acids (cfDNA and cfRNA) in blood through a simple operational process, enabling various downstream nucleic acid detectio

Updated on:March 30,2024

BMI's relation to cancer therapy mortality risks not so straightforward, study finds

byOsaka Metropolitan UniversityFor non-small cell lung cancer treatment, immunotherapy seems to pose less risk for persons under a certain BMI, while conventional chemotherapy appears optimal fo

Updated on: September 27,2024

BMI's relation to cancer therapy mortality risks not so straightforward, study finds

byOsaka Metropolitan UniversityFor non-small cell lung cancer treatment, immunotherapy seems to pose less risk for persons under a certain BMI, while conventional chemotherapy appears optimal fo

Updated on:September 27,2024

Target discovered for the treatment of pancreatic cancer

byKiel UniversityAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainA team at the Institute of Biochemistry at Kiel University has found a

Updated on: July 05,2024

Target discovered for the treatment of pancreatic cancer

byKiel UniversityAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainA team at the Institute of Biochemistry at Kiel University has found a

Updated on:July 05,2024

Some breast cancer patients are missing out on genetic counseling

by University of MichiganSteven Katz, M.D., MPH. Credit: Michigan MedicineAs new genes are linked to breast cancer occurring in families and as genetic testing becomes more important in directing

Updated on: May 21,2024

Some breast cancer patients are missing out on genetic counseling

by University of MichiganSteven Katz, M.D., MPH. Credit: Michigan MedicineAs new genes are linked to breast cancer occurring in families and as genetic testing becomes more important in directing

Updated on:May 21,2024

Molecule Linking Cancer Driver and Cell Death Genes May Be Effective Against DLBCL

November 2023Thomas R. CollinsMolecules that link cancer driver genes and promoters of cell death genes produce potent killing of diffuse large B-cell lymphoma (DLBCL) cells, according to findings pub

Updated on: February 18,2024

Molecule Linking Cancer Driver and Cell Death Genes May Be Effective Against DLBCL

November 2023Thomas R. CollinsMolecules that link cancer driver genes and promoters of cell death genes produce potent killing of diffuse large B-cell lymphoma (DLBCL) cells, according to findings pub

Updated on:February 18,2024