Study uncovers epigenetic source of resistance to targeted therapy in EGFR-mutant lung cancer

by Dana-Farber Cancer InstituteCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.07.005When lung cancers driven by mutations in the EGFR gene become resistant to osimertinib or othe

Updated on: February 01,2024

Study uncovers epigenetic source of resistance to targeted therapy in EGFR-mutant lung cancer

by Dana-Farber Cancer InstituteCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.07.005When lung cancers driven by mutations in the EGFR gene become resistant to osimertinib or othe

Updated on:February 01,2024

1999 to 2018 saw increase in cancer survivors with functional limitation, finds research

by Elana GotkineFrom 1999 to 2018, there was a more than twofold increase in the number of cancer survivors reporting functional limitations, according to a research letter published online May 11 in&

Updated on: January 23,2024

1999 to 2018 saw increase in cancer survivors with functional limitation, finds research

by Elana GotkineFrom 1999 to 2018, there was a more than twofold increase in the number of cancer survivors reporting functional limitations, according to a research letter published online May 11 in&

Updated on:January 23,2024

Early palliative care offers no extra benefit for mesothelioma patients

by Curtin UniversityCredit: CC0 Public DomainEarly specialist palliative care treatment does not improve the quality of life for patients diagnosed with the rare cancer mesothelioma when compared

Updated on: April 20,2024

Early palliative care offers no extra benefit for mesothelioma patients

by Curtin UniversityCredit: CC0 Public DomainEarly specialist palliative care treatment does not improve the quality of life for patients diagnosed with the rare cancer mesothelioma when compared

Updated on:April 20,2024

Skin cancer rewires its energy systems to spread more efficiently, finds study

by Queen Mary, University of LondonDifferent modes of migration and mitochondrial metabolism.a,bOxygen consumption rate (OCR) from cells embedded in a 3D collagen I matrix (n = 

Updated on: February 18,2024

Skin cancer rewires its energy systems to spread more efficiently, finds study

by Queen Mary, University of LondonDifferent modes of migration and mitochondrial metabolism.a,bOxygen consumption rate (OCR) from cells embedded in a 3D collagen I matrix (n = 

Updated on:February 18,2024

New technique adds to the expanding suite of TAPS capabilities

byLudwig Cancer ResearchDevelopment of wglrTAPS. (A) Schematic representation of the wglrTAPS. (B) Sequence length distribution of wglrTAPS HiFi read. (C) Conversion rate of wglrTAPS at methylat

Updated on: January 13,2024

New technique adds to the expanding suite of TAPS capabilities

byLudwig Cancer ResearchDevelopment of wglrTAPS. (A) Schematic representation of the wglrTAPS. (B) Sequence length distribution of wglrTAPS HiFi read. (C) Conversion rate of wglrTAPS at methylat

Updated on:January 13,2024

Specialized immune cells carry potential for new cancer immunotherapies

byLeiden UniversityTumor-infiltrating Vδ1 and Vδ3 T cell subsets display hallmarks of cytotoxic activity in MMR-d colon cancers. a, UMAP embedding showing the clustering of γδ T cells (n = 4,442

Updated on: January 23,2024

Specialized immune cells carry potential for new cancer immunotherapies

byLeiden UniversityTumor-infiltrating Vδ1 and Vδ3 T cell subsets display hallmarks of cytotoxic activity in MMR-d colon cancers. a, UMAP embedding showing the clustering of γδ T cells (n = 4,442

Updated on:January 23,2024

Multiple myeloma survival down with high ADAR1 RNA expression

(HealthDay)—Amplification of the inflammation-responsive RNA editase adenosine deaminase acting on RNA (ADAR)1 gene is associated with reduced survival in multiple myeloma (MM), according to a study p

Updated on: March 30,2024

Multiple myeloma survival down with high ADAR1 RNA expression

(HealthDay)—Amplification of the inflammation-responsive RNA editase adenosine deaminase acting on RNA (ADAR)1 gene is associated with reduced survival in multiple myeloma (MM), according to a study p

Updated on:March 30,2024

A machine learning-based algorithm to predict which cancer patients benefit from immunotherapy

by Institute for Research in Biomedicine (IRB Barcelona)Credit: CC0 Public DomainScientists at the Institute for Research in Biomedicine (IRB Barcelona), in collaboration with the Centre for Geno

Updated on: May 20,2024

A machine learning-based algorithm to predict which cancer patients benefit from immunotherapy

by Institute for Research in Biomedicine (IRB Barcelona)Credit: CC0 Public DomainScientists at the Institute for Research in Biomedicine (IRB Barcelona), in collaboration with the Centre for Geno

Updated on:May 20,2024

The hitchhiker's guide to defeating glioblastoma

by Brigham and Women's HospitalGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0In cancer therapeutics research, microRNAs—tiny strings of nucleotides that get churned out inside

Updated on: April 18,2024

The hitchhiker's guide to defeating glioblastoma

by Brigham and Women's HospitalGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0In cancer therapeutics research, microRNAs—tiny strings of nucleotides that get churned out inside

Updated on:April 18,2024

Predicting efficacy of neoadjuvant chemotherapy for advanced gastric cancer

by Zhang Nannan,Chinese Academy of SciencesProcess for predicting the NACT efficacy in AGC. Credit: SIBETGastric cancer is a common malignant tumor that originates from the gastric mucosal epith

Updated on: February 24,2024

Predicting efficacy of neoadjuvant chemotherapy for advanced gastric cancer

by Zhang Nannan,Chinese Academy of SciencesProcess for predicting the NACT efficacy in AGC. Credit: SIBETGastric cancer is a common malignant tumor that originates from the gastric mucosal epith

Updated on:February 24,2024

'Fighting' cancer may detract men from palliative care

by University of Rochester Medical CenterMen with advanced cancer are 30 percent less likely than women to consider palliative care, according to a University of Rochester Medical Center study.Re

Updated on: March 01,2024

'Fighting' cancer may detract men from palliative care

by University of Rochester Medical CenterMen with advanced cancer are 30 percent less likely than women to consider palliative care, according to a University of Rochester Medical Center study.Re

Updated on:March 01,2024

Novel bioassay predicts cancer patients' response to immunotherapy

byBen-Gurion University of the NegevIcAR response to fresh and fixed PDXs and generation of an IcAR score.(A) Schematic representation of the IcAR assay protocol. Following flow cytometry determ

Updated on: January 12,2024

Novel bioassay predicts cancer patients' response to immunotherapy

byBen-Gurion University of the NegevIcAR response to fresh and fixed PDXs and generation of an IcAR score.(A) Schematic representation of the IcAR assay protocol. Following flow cytometry determ

Updated on:January 12,2024