Mapping lactylome in hepatocellular carcinoma reveals new mechanisms of metabolic adaptation

by Liu Jia,Chinese Academy of SciencesCredit: Pixabay/CC0 Public DomainLactate, a major product of glycolysis in mammals, is significantly increased in pathological states such as tumors, sepsis

Updated on: February 20,2024

Mapping lactylome in hepatocellular carcinoma reveals new mechanisms of metabolic adaptation

by Liu Jia,Chinese Academy of SciencesCredit: Pixabay/CC0 Public DomainLactate, a major product of glycolysis in mammals, is significantly increased in pathological states such as tumors, sepsis

Updated on:February 20,2024

Researchers determine epigenetic origin of docetaxel-resistant breast cancer

by IDIBELL-Bellvitge Biomedical Research InstituteResearchers at the Bellvitge Biomedical Research Institute (IDIBELL), published today in Molecular Cancer Research a study where they identify me

Updated on: June 08,2024

Researchers determine epigenetic origin of docetaxel-resistant breast cancer

by IDIBELL-Bellvitge Biomedical Research InstituteResearchers at the Bellvitge Biomedical Research Institute (IDIBELL), published today in Molecular Cancer Research a study where they identify me

Updated on:June 08,2024

Study illuminates precancerous 'clonal outgrowth' in blood cells

byWeill Cornell Medical CollegeCredit: CC0 Public DomainA common, spontaneous mutation in blood stem cells, which has been linked to higher risks of blood cancer and cardiovascular disease, may

Updated on: January 22,2024

Study illuminates precancerous 'clonal outgrowth' in blood cells

byWeill Cornell Medical CollegeCredit: CC0 Public DomainA common, spontaneous mutation in blood stem cells, which has been linked to higher risks of blood cancer and cardiovascular disease, may

Updated on:January 22,2024

Researchers suggest new way to target third most common oncogene, TERT

by Garth Sundem,CU Anschutz Medical CampusChromosome, showing telomeres in pink. Credit: CUHealthy cells have a built-in self-destruct mechanism: Strands of DNA called "telomeres" act

Updated on: March 01,2024

Researchers suggest new way to target third most common oncogene, TERT

by Garth Sundem,CU Anschutz Medical CampusChromosome, showing telomeres in pink. Credit: CUHealthy cells have a built-in self-destruct mechanism: Strands of DNA called "telomeres" act

Updated on:March 01,2024

Aerobic exercise cuts chemotherapy-induced peripheral neuropathy symptoms

by Lori SolomonA six-month aerobic exercise intervention significantly improves self-reported chemotherapy-induced peripheral neuropathy (CIPN) among patients treated for ovarian cancer, according to

Updated on: February 23,2024

Aerobic exercise cuts chemotherapy-induced peripheral neuropathy symptoms

by Lori SolomonA six-month aerobic exercise intervention significantly improves self-reported chemotherapy-induced peripheral neuropathy (CIPN) among patients treated for ovarian cancer, according to

Updated on:February 23,2024

A new strategy 'raises the volume' of gut-body communication

by Ana María Rodríguez, Ph.d.,Baylor College of MedicineCredit: CC0 Public DomainThroughout the gastrointestinal tract there are specialized hormone-producing cells called enteroendocrine cells

Updated on: May 23,2024

A new strategy 'raises the volume' of gut-body communication

by Ana María Rodríguez, Ph.d.,Baylor College of MedicineCredit: CC0 Public DomainThroughout the gastrointestinal tract there are specialized hormone-producing cells called enteroendocrine cells

Updated on:May 23,2024

Researchers create new tool for assessing risk of kidney injury after chemotherapy

by Brigham and Women’s HospitalCredit: Pixabay/CC0 Public DomainUsing patient data from six major U.S. cancer centers, Brigham researchers and collaborators developed a risk prediction model for

Updated on: March 30,2024

Researchers create new tool for assessing risk of kidney injury after chemotherapy

by Brigham and Women’s HospitalCredit: Pixabay/CC0 Public DomainUsing patient data from six major U.S. cancer centers, Brigham researchers and collaborators developed a risk prediction model for

Updated on:March 30,2024

The protein behind immunotherapy resistance

byEcole Polytechnique Federale de LausanneTumor with FMRP-deficient cancer cells (in green) being infiltrated and attached by killer (CD8) T cells. Credit: Jeremy Guillot (Hanahan Lab – EPFL).Im

Updated on: January 02,2024

The protein behind immunotherapy resistance

byEcole Polytechnique Federale de LausanneTumor with FMRP-deficient cancer cells (in green) being infiltrated and attached by killer (CD8) T cells. Credit: Jeremy Guillot (Hanahan Lab – EPFL).Im

Updated on:January 02,2024

Previously unidentified proteins suggest new way to diagnose ovarian cancer

by Nagoya UniversityExtracellular vesicles (EVs) are vesicles with lipid-bilayer structures (shown in center), and three proteins expressed on small EVs called exosomes (shown in red, green, blue

Updated on: February 23,2024

Previously unidentified proteins suggest new way to diagnose ovarian cancer

by Nagoya UniversityExtracellular vesicles (EVs) are vesicles with lipid-bilayer structures (shown in center), and three proteins expressed on small EVs called exosomes (shown in red, green, blue

Updated on:February 23,2024

Boosting the effects of a particular microRNA may benefit patients with cervical cancer

by WileyHigh grade dysplasia (carcinoma in situ) in the uterine cervix. The abnormal epithelium is extending into a mucus gland to the left of centre. This disease can progress to invasive cancer

Updated on: February 18,2024

Boosting the effects of a particular microRNA may benefit patients with cervical cancer

by WileyHigh grade dysplasia (carcinoma in situ) in the uterine cervix. The abnormal epithelium is extending into a mucus gland to the left of centre. This disease can progress to invasive cancer

Updated on:February 18,2024

Protein could offer therapeutic target for pancreatic cancer

by The Francis Crick InstituteHuman pancreatic ductal adenocarcinoma showing high levels of CD9 (red). Credit: Francis Crick InstituteA protein that drives growth of pancreatic cancer, and which

Updated on: March 01,2024

Protein could offer therapeutic target for pancreatic cancer

by The Francis Crick InstituteHuman pancreatic ductal adenocarcinoma showing high levels of CD9 (red). Credit: Francis Crick InstituteA protein that drives growth of pancreatic cancer, and which

Updated on:March 01,2024

Sticky cell fingers help keep breast tumors contained

by University of TurkuBreast cancer cells break through the basement membrane acting as a biological barrier. In the image, the finger-like projections formed by the actin of cancer cells invadin

Updated on: February 24,2024

Sticky cell fingers help keep breast tumors contained

by University of TurkuBreast cancer cells break through the basement membrane acting as a biological barrier. In the image, the finger-like projections formed by the actin of cancer cells invadin

Updated on:February 24,2024