New review on p53 biology and reactivation in blood cancers

byKarolinska InstitutetA simplified scheme of p53 regulation in cells upon stress and the drugs currently evaluated in clinical trials for p53 reactivation for improved therapy in MDS and AML. C

Updated on: March 30,2024

New review on p53 biology and reactivation in blood cancers

byKarolinska InstitutetA simplified scheme of p53 regulation in cells upon stress and the drugs currently evaluated in clinical trials for p53 reactivation for improved therapy in MDS and AML. C

Updated on:March 30,2024

Study uncovers epigenetic source of resistance to targeted therapy in EGFR-mutant lung cancer

by Dana-Farber Cancer InstituteCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.07.005When lung cancers driven by mutations in the EGFR gene become resistant to osimertinib or othe

Updated on: February 01,2024

Study uncovers epigenetic source of resistance to targeted therapy in EGFR-mutant lung cancer

by Dana-Farber Cancer InstituteCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.07.005When lung cancers driven by mutations in the EGFR gene become resistant to osimertinib or othe

Updated on:February 01,2024

Drinking alcohol not likely to increase risk of a breast cancer recurrence

by Kaiser PermanenteCredit: CC0 Public DomainA Kaiser Permanente study provides new information that may help oncologists answer one of the most common questions they hear from breast cancer surv

Updated on: February 01,2024

Drinking alcohol not likely to increase risk of a breast cancer recurrence

by Kaiser PermanenteCredit: CC0 Public DomainA Kaiser Permanente study provides new information that may help oncologists answer one of the most common questions they hear from breast cancer surv

Updated on:February 01,2024

Tumor-induced B cell changes reveal potential biomarker for treatment response in triple negative breast cancer

byBaylor College of MedicineCredit: Pixabay/CC0 Public DomainResearchers at Baylor College of Medicine and collaborating institutions have discovered new insights into tumor-induced B cell chang

Updated on: September 28,2024

Tumor-induced B cell changes reveal potential biomarker for treatment response in triple negative breast cancer

byBaylor College of MedicineCredit: Pixabay/CC0 Public DomainResearchers at Baylor College of Medicine and collaborating institutions have discovered new insights into tumor-induced B cell chang

Updated on:September 28,2024

A window into the changing tumor microenvironment

by Ludwig Cancer ResearchGraphical abstract. Credit:iScience(2022). DOI: 10.1016/j.isci.2022.104570Researchers led by Ludwig Lausanne's Anoek Zomer, Davide Croci and Johanna Joyce

Updated on: February 18,2024

A window into the changing tumor microenvironment

by Ludwig Cancer ResearchGraphical abstract. Credit:iScience(2022). DOI: 10.1016/j.isci.2022.104570Researchers led by Ludwig Lausanne's Anoek Zomer, Davide Croci and Johanna Joyce

Updated on:February 18,2024

Study finds earlier mammograms for women with family history of breast cancer may not be needed

by Stephanie Winn,UC DavisCredit: Unsplash/CC0 Public DomainA new study released in the journalCancerreconsiders guidelines for when to start screening with mammograms if a woman has

Updated on: January 23,2024

Study finds earlier mammograms for women with family history of breast cancer may not be needed

by Stephanie Winn,UC DavisCredit: Unsplash/CC0 Public DomainA new study released in the journalCancerreconsiders guidelines for when to start screening with mammograms if a woman has

Updated on:January 23,2024

Inhibition of ribosome biogenesis as a novel approach for multi-stage cancer treatment

by Uppsala UniversityCredit: Uppsala UniversityNearly 90 percent of all cancer patient deaths are due to metastasis. A study from Uppsala University shows that a process that allows the cells to

Updated on: May 11,2024

Inhibition of ribosome biogenesis as a novel approach for multi-stage cancer treatment

by Uppsala UniversityCredit: Uppsala UniversityNearly 90 percent of all cancer patient deaths are due to metastasis. A study from Uppsala University shows that a process that allows the cells to

Updated on:May 11,2024

Researchers determine epigenetic origin of docetaxel-resistant breast cancer

by IDIBELL-Bellvitge Biomedical Research InstituteResearchers at the Bellvitge Biomedical Research Institute (IDIBELL), published today in Molecular Cancer Research a study where they identify me

Updated on: June 08,2024

Researchers determine epigenetic origin of docetaxel-resistant breast cancer

by IDIBELL-Bellvitge Biomedical Research InstituteResearchers at the Bellvitge Biomedical Research Institute (IDIBELL), published today in Molecular Cancer Research a study where they identify me

Updated on:June 08,2024

The sugar-attaching enzyme that defines colon cancer

by American Society for Biochemistry and Molecular BiologyThe enzyme GalNAc-T6 is selectively up-regulated in colon adenocarcinomas, and its expression is associated with a cancer-like growth pat

Updated on: April 14,2024

The sugar-attaching enzyme that defines colon cancer

by American Society for Biochemistry and Molecular BiologyThe enzyme GalNAc-T6 is selectively up-regulated in colon adenocarcinomas, and its expression is associated with a cancer-like growth pat

Updated on:April 14,2024

Researchers show potential liver cancer treatment by targeting cancer stem-like cells

by National University of SingaporeLiver cancer stem-like cells grown as tumourspheres that are sensitive to JAK/STAT small molecule inhibitors. Credit: National University of SingaporeLiver canc

Updated on: March 01,2024

Researchers show potential liver cancer treatment by targeting cancer stem-like cells

by National University of SingaporeLiver cancer stem-like cells grown as tumourspheres that are sensitive to JAK/STAT small molecule inhibitors. Credit: National University of SingaporeLiver canc

Updated on:March 01,2024

A new strategy 'raises the volume' of gut-body communication

by Ana María Rodríguez, Ph.d.,Baylor College of MedicineCredit: CC0 Public DomainThroughout the gastrointestinal tract there are specialized hormone-producing cells called enteroendocrine cells

Updated on: May 23,2024

A new strategy 'raises the volume' of gut-body communication

by Ana María Rodríguez, Ph.d.,Baylor College of MedicineCredit: CC0 Public DomainThroughout the gastrointestinal tract there are specialized hormone-producing cells called enteroendocrine cells

Updated on:May 23,2024

Depression linked to deadly inflammation in lung cancer patients

by Jeff Grabmeier,The Ohio State UniversityKaplan Meier survival curve for NSCLC patients stratified by NLR systemic inflammation, NLR < 5 and NLR ≥ 5 (n = 184), showing worse survival probab

Updated on: January 30,2024

Depression linked to deadly inflammation in lung cancer patients

by Jeff Grabmeier,The Ohio State UniversityKaplan Meier survival curve for NSCLC patients stratified by NLR systemic inflammation, NLR < 5 and NLR ≥ 5 (n = 184), showing worse survival probab

Updated on:January 30,2024