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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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A new strategy 'raises the volume' of gut-body communication

A new strategy 'raises the volume' of gut-body communication

by Ana María Rodríguez, Ph.d.,Baylor College of MedicineCredit: CC0 Public DomainThroughout the gastrointestinal tract there are specialized hormone-producing cells called enteroendocrine cells

A new strategy 'raises the volume' of gut-body communication

by Ana María Rodríguez, Ph.d.,Baylor College of MedicineCredit: CC0 Public DomainThroughout the gastrointestinal tract there are specialized hormone-producing cells called enteroendocrine cells
Depression linked to deadly inflammation in lung cancer patients

Depression linked to deadly inflammation in lung cancer patients

by Jeff Grabmeier,The Ohio State UniversityKaplan Meier survival curve for NSCLC patients stratified by NLR systemic inflammation, NLR < 5 and NLR ≥ 5 (n = 184), showing worse survival probab

Depression linked to deadly inflammation in lung cancer patients

by Jeff Grabmeier,The Ohio State UniversityKaplan Meier survival curve for NSCLC patients stratified by NLR systemic inflammation, NLR < 5 and NLR ≥ 5 (n = 184), showing worse survival probab
Immune system B-cells can help predict HER2-positive breast cancer treatment response

Immune system B-cells can help predict HER2-positive breast cancer treatment response

byUNC Lineberger Comprehensive Cancer CenterThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: NCI Ce

Immune system B-cells can help predict HER2-positive breast cancer treatment response

byUNC Lineberger Comprehensive Cancer CenterThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: NCI Ce
Previously unidentified proteins suggest new way to diagnose ovarian cancer

Previously unidentified proteins suggest new way to diagnose ovarian cancer

by Nagoya UniversityExtracellular vesicles (EVs) are vesicles with lipid-bilayer structures (shown in center), and three proteins expressed on small EVs called exosomes (shown in red, green, blue

Previously unidentified proteins suggest new way to diagnose ovarian cancer

by Nagoya UniversityExtracellular vesicles (EVs) are vesicles with lipid-bilayer structures (shown in center), and three proteins expressed on small EVs called exosomes (shown in red, green, blue
Study: Drugs reprogram genes in breast tumors to prevent endocrine resistance

Study: Drugs reprogram genes in breast tumors to prevent endocrine resistance

by Sharita Forrest,University of Illinois at Urbana-ChampaignTargeting estrogen receptor-positive breast tumors with the XPO1 antagonist selinexor and the tamoxifen byproduct 4-OHT simultaneousl

Study: Drugs reprogram genes in breast tumors to prevent endocrine resistance

by Sharita Forrest,University of Illinois at Urbana-ChampaignTargeting estrogen receptor-positive breast tumors with the XPO1 antagonist selinexor and the tamoxifen byproduct 4-OHT simultaneousl
Scientists advise caution in immunotherapy research

Scientists advise caution in immunotherapy research

by Yale UniversityCredit: CC0 Public DomainIn a new study, Yale Cancer Center (YCC) scientists suggest that as the number of clinical trials in cancer immunotherapy grows exponentially, some caut

Scientists advise caution in immunotherapy research

by Yale UniversityCredit: CC0 Public DomainIn a new study, Yale Cancer Center (YCC) scientists suggest that as the number of clinical trials in cancer immunotherapy grows exponentially, some caut
New study shows recently diagnosed adult cancer survivors at higher risk for bone fractures

New study shows recently diagnosed adult cancer survivors at higher risk for bone fractures

byAmerican Cancer SocietyAdult cancer survivors at increased risk for bone fractures. Credit: American Cancer SocietyAdult cancer survivors, particularly those diagnosed within five years and/or

New study shows recently diagnosed adult cancer survivors at higher risk for bone fractures

byAmerican Cancer SocietyAdult cancer survivors at increased risk for bone fractures. Credit: American Cancer SocietyAdult cancer survivors, particularly those diagnosed within five years and/or
Study uncovers epigenetic source of resistance to targeted therapy in EGFR-mutant lung cancer

Study uncovers epigenetic source of resistance to targeted therapy in EGFR-mutant lung cancer

by Dana-Farber Cancer InstituteCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.07.005When lung cancers driven by mutations in the EGFR gene become resistant to osimertinib or othe

Study uncovers epigenetic source of resistance to targeted therapy in EGFR-mutant lung cancer

by Dana-Farber Cancer InstituteCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.07.005When lung cancers driven by mutations in the EGFR gene become resistant to osimertinib or othe
Molecule Linking Cancer Driver and Cell Death Genes May Be Effective Against DLBCL

Molecule Linking Cancer Driver and Cell Death Genes May Be Effective Against DLBCL

November 2023Thomas R. CollinsMolecules that link cancer driver genes and promoters of cell death genes produce potent killing of diffuse large B-cell lymphoma (DLBCL) cells, according to findings pub

Molecule Linking Cancer Driver and Cell Death Genes May Be Effective Against DLBCL

November 2023Thomas R. CollinsMolecules that link cancer driver genes and promoters of cell death genes produce potent killing of diffuse large B-cell lymphoma (DLBCL) cells, according to findings pub
Inhibition of histone deacetylase 2 reduces MDM2 expression and reduces tumor growth in dedifferentiated liposarcoma

Inhibition of histone deacetylase 2 reduces MDM2 expression and reduces tumor growth in dedifferentiated liposarcoma

by OncotargetElevated HDAC2 mRNA expression is poorly prognostic in DDLPS. (A) mRNA expression of HDAC2 and disease-free survival (DFS) data from 52 subjects with DDLPS from The Cancer Genome Atlas (T

Inhibition of histone deacetylase 2 reduces MDM2 expression and reduces tumor growth in dedifferentiated liposarcoma

by OncotargetElevated HDAC2 mRNA expression is poorly prognostic in DDLPS. (A) mRNA expression of HDAC2 and disease-free survival (DFS) data from 52 subjects with DDLPS from The Cancer Genome Atlas (T
New report finds smoking rates, alcohol use, physical inactivity decreased during COVID-19

New report finds smoking rates, alcohol use, physical inactivity decreased during COVID-19

byAmerican Cancer SocietyNew ACS Report. Credit: American Cancer SocietyIn a new report, American Cancer Society (ACS) researchers discovered both favorable and unfavorable changes in major canc

New report finds smoking rates, alcohol use, physical inactivity decreased during COVID-19

byAmerican Cancer SocietyNew ACS Report. Credit: American Cancer SocietyIn a new report, American Cancer Society (ACS) researchers discovered both favorable and unfavorable changes in major canc
Young women often delay looking into breast symptoms, research finds

Young women often delay looking into breast symptoms, research finds

by Dennis ThompsonYoung women who find a lump or other potential signs of breast cancer often delay for weeks before finally seeing a doctor, a new study shows.On average, young women waited two weeks

Young women often delay looking into breast symptoms, research finds

by Dennis ThompsonYoung women who find a lump or other potential signs of breast cancer often delay for weeks before finally seeing a doctor, a new study shows.On average, young women waited two weeks