Study uncovers epigenetic source of resistance to targeted therapy in EGFR-mutant lung cancer

by Dana-Farber Cancer InstituteCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.07.005When lung cancers driven by mutations in the EGFR gene become resistant to osimertinib or othe

Updated on: February 01,2024

Study uncovers epigenetic source of resistance to targeted therapy in EGFR-mutant lung cancer

by Dana-Farber Cancer InstituteCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.07.005When lung cancers driven by mutations in the EGFR gene become resistant to osimertinib or othe

Updated on:February 01,2024

Studies give new insights on immunotherapy in elderly patients with advanced NSCLC

by European Society for Medical OncologyTwo studies to be reported at ELCC 2019 provide new insights on the efficacy and safety of immunotherapy in elderly patients with advanced non-small-cell l

Updated on: May 31,2024

Studies give new insights on immunotherapy in elderly patients with advanced NSCLC

by European Society for Medical OncologyTwo studies to be reported at ELCC 2019 provide new insights on the efficacy and safety of immunotherapy in elderly patients with advanced non-small-cell l

Updated on:May 31,2024

Specialized immune cells carry potential for new cancer immunotherapies

byLeiden UniversityTumor-infiltrating Vδ1 and Vδ3 T cell subsets display hallmarks of cytotoxic activity in MMR-d colon cancers. a, UMAP embedding showing the clustering of γδ T cells (n = 4,442

Updated on: January 23,2024

Specialized immune cells carry potential for new cancer immunotherapies

byLeiden UniversityTumor-infiltrating Vδ1 and Vδ3 T cell subsets display hallmarks of cytotoxic activity in MMR-d colon cancers. a, UMAP embedding showing the clustering of γδ T cells (n = 4,442

Updated on:January 23,2024

Researchers key to advance care planning with cancer clinical trial patients

by University of Pennsylvania School of NursingConnie M. Ulrich, PhD, RN, FAAN, the Lillian S. Brunner Chair in Medical and Surgical Nursing at the University of Pennsylvania School of Nursing (P

Updated on: June 15,2024

Researchers key to advance care planning with cancer clinical trial patients

by University of Pennsylvania School of NursingConnie M. Ulrich, PhD, RN, FAAN, the Lillian S. Brunner Chair in Medical and Surgical Nursing at the University of Pennsylvania School of Nursing (P

Updated on:June 15,2024

Artificial intelligence-aided colonoscopy does not increase cancer detection

by Elana GotkineAdenoma and polyp detection rates (ADR/PDR) are lower with use of artificial intelligence-aided colonoscopy (AIAC), according to a study published in the November issue ofThe&nbs

Updated on: January 02,2024

Artificial intelligence-aided colonoscopy does not increase cancer detection

by Elana GotkineAdenoma and polyp detection rates (ADR/PDR) are lower with use of artificial intelligence-aided colonoscopy (AIAC), according to a study published in the November issue ofThe&nbs

Updated on:January 02,2024

Study: Innovative pancreatic cancer treatment may rev up immune system

by University of Rochester Medical CenterImmune cells (orange) and blood vessels (green) inside a tumor. Credit: University of Rochester Medical CenterA University of Rochester Wilmot Cancer Inst

Updated on: March 01,2024

Study: Innovative pancreatic cancer treatment may rev up immune system

by University of Rochester Medical CenterImmune cells (orange) and blood vessels (green) inside a tumor. Credit: University of Rochester Medical CenterA University of Rochester Wilmot Cancer Inst

Updated on:March 01,2024

Enhanced anticancer compound may allow precise activation and tracking of treatment

by The Wistar InstituteCredit: The Wistar InstituteResearchers at The Wistar Institute and the University of South Florida have advanced a novel compound that specifically targets the endoplasmic

Updated on: April 18,2024

Enhanced anticancer compound may allow precise activation and tracking of treatment

by The Wistar InstituteCredit: The Wistar InstituteResearchers at The Wistar Institute and the University of South Florida have advanced a novel compound that specifically targets the endoplasmic

Updated on:April 18,2024

Novel pretargeted radionuclide therapy for HER2-expressing cancers shows promise

by Society of Nuclear Medicine and Molecular ImagingTransversal (A), coronal (B), sagittal (C) nanoSPECT/CT images and maximum intensity projection (D) obtained 30 h after injection of pretargeted&nbs

Updated on: March 06,2024

Novel pretargeted radionuclide therapy for HER2-expressing cancers shows promise

by Society of Nuclear Medicine and Molecular ImagingTransversal (A), coronal (B), sagittal (C) nanoSPECT/CT images and maximum intensity projection (D) obtained 30 h after injection of pretargeted&nbs

Updated on:March 06,2024

Researchers identify potential biomarker to distinguish two aggressive types of brain tumors in children

by Johns Hopkins University School of MedicineSMYD3 overexpression activates the EGFR pathway in CHLA01 cells. (A) Localization of endogenous SMYD3. Representative 60x Z-stack confocal images sho

Updated on: January 30,2024

Researchers identify potential biomarker to distinguish two aggressive types of brain tumors in children

by Johns Hopkins University School of MedicineSMYD3 overexpression activates the EGFR pathway in CHLA01 cells. (A) Localization of endogenous SMYD3. Representative 60x Z-stack confocal images sho

Updated on:January 30,2024

Study: Drugs reprogram genes in breast tumors to prevent endocrine resistance

by Sharita Forrest,University of Illinois at Urbana-ChampaignTargeting estrogen receptor-positive breast tumors with the XPO1 antagonist selinexor and the tamoxifen byproduct 4-OHT simultaneousl

Updated on: May 27,2024

Study: Drugs reprogram genes in breast tumors to prevent endocrine resistance

by Sharita Forrest,University of Illinois at Urbana-ChampaignTargeting estrogen receptor-positive breast tumors with the XPO1 antagonist selinexor and the tamoxifen byproduct 4-OHT simultaneousl

Updated on:May 27,2024

Researchers study how altered protein degradation contributes to the development of tumors

by Institute for Research in Biomedicine (IRB Barcelona)To ensure adequate levels of proteins in the cell, a strict quality control system is responsible for tagging the proteins with ubiquitin f

Updated on: March 06,2024

Researchers study how altered protein degradation contributes to the development of tumors

by Institute for Research in Biomedicine (IRB Barcelona)To ensure adequate levels of proteins in the cell, a strict quality control system is responsible for tagging the proteins with ubiquitin f

Updated on:March 06,2024

Cancer deaths in Italy: Environmental pollution plays an important role

by Università di BolognaGraphical abstract. Credit:Science of The Total Environment(2022). DOI: 10.1016/j.scitotenv.2022.158439Today, cancer represents the second leading cause of death in

Updated on: February 18,2024

Cancer deaths in Italy: Environmental pollution plays an important role

by Università di BolognaGraphical abstract. Credit:Science of The Total Environment(2022). DOI: 10.1016/j.scitotenv.2022.158439Today, cancer represents the second leading cause of death in

Updated on:February 18,2024