A new strategy 'raises the volume' of gut-body communication

by Ana María Rodríguez, Ph.d.,Baylor College of MedicineCredit: CC0 Public DomainThroughout the gastrointestinal tract there are specialized hormone-producing cells called enteroendocrine cells

Updated on: May 23,2024

A new strategy 'raises the volume' of gut-body communication

by Ana María Rodríguez, Ph.d.,Baylor College of MedicineCredit: CC0 Public DomainThroughout the gastrointestinal tract there are specialized hormone-producing cells called enteroendocrine cells

Updated on:May 23,2024

Immune system B-cells can help predict HER2-positive breast cancer treatment response

byUNC Lineberger Comprehensive Cancer CenterThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: NCI Ce

Updated on: January 02,2024

Immune system B-cells can help predict HER2-positive breast cancer treatment response

byUNC Lineberger Comprehensive Cancer CenterThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: NCI Ce

Updated on:January 02,2024

Investigating the immunoregulatory protein CD200 as a potentially lucrative yet elusive target for cancer therapy

by Impact Journals LLCMultiple mechanisms underly the pro-tumorigenic role of CD200. Credit: 2023 Shao and Owens.A new research perspective titled "The immunoregulatory protein CD200 as a potenti

Updated on: January 30,2024

Investigating the immunoregulatory protein CD200 as a potentially lucrative yet elusive target for cancer therapy

by Impact Journals LLCMultiple mechanisms underly the pro-tumorigenic role of CD200. Credit: 2023 Shao and Owens.A new research perspective titled "The immunoregulatory protein CD200 as a potenti

Updated on:January 30,2024

Cancer deaths in Italy: Environmental pollution plays an important role

by Università di BolognaGraphical abstract. Credit:Science of The Total Environment(2022). DOI: 10.1016/j.scitotenv.2022.158439Today, cancer represents the second leading cause of death in

Updated on: February 18,2024

Cancer deaths in Italy: Environmental pollution plays an important role

by Università di BolognaGraphical abstract. Credit:Science of The Total Environment(2022). DOI: 10.1016/j.scitotenv.2022.158439Today, cancer represents the second leading cause of death in

Updated on:February 18,2024

Deep proteomic profiling reveals possible therapeutic targets for medulloblastoma

byTranslational Genomics Research InstituteSample overview and subgroup classification. (A) Common molecular alterations and subgroup classifications of 20 MB PDX models. (B) Partial least squar

Updated on: January 04,2024

Deep proteomic profiling reveals possible therapeutic targets for medulloblastoma

byTranslational Genomics Research InstituteSample overview and subgroup classification. (A) Common molecular alterations and subgroup classifications of 20 MB PDX models. (B) Partial least squar

Updated on:January 04,2024

Doctors are being sexually harassed at work—this needs to stop

by Louise Stone,The ConversationCredit: Unsplash/CC0 Public DomainDominique Leewas training in radiation oncology when she was invited to join her supervisor to discuss a training opportun

Updated on: May 25,2024

Doctors are being sexually harassed at work—this needs to stop

by Louise Stone,The ConversationCredit: Unsplash/CC0 Public DomainDominique Leewas training in radiation oncology when she was invited to join her supervisor to discuss a training opportun

Updated on:May 25,2024

Study shows checkpoint inhibitor prolongs survival in patients with certain head and neck cancers

by Anne Doerr,Yale UniversityCredit: stock.adobe.comThe checkpoint inhibitor pembrolizumab (Keytruda) increases the survival time of patients with advanced head and neck cancers, according to a

Updated on: May 31,2024

Study shows checkpoint inhibitor prolongs survival in patients with certain head and neck cancers

by Anne Doerr,Yale UniversityCredit: stock.adobe.comThe checkpoint inhibitor pembrolizumab (Keytruda) increases the survival time of patients with advanced head and neck cancers, according to a

Updated on:May 31,2024

Research unveils genetic characteristics and improved prognosis of triple-negative apocrine carcinoma

by JooHyeon Heo,Ulsan National Institute of Science and TechnologySomatic Point Mutations in TNAC and LK-TNBC. The top 16 significantly mutated genes as determined by the dNdScv algorithm (p &lt

Updated on: February 18,2024

Research unveils genetic characteristics and improved prognosis of triple-negative apocrine carcinoma

by JooHyeon Heo,Ulsan National Institute of Science and TechnologySomatic Point Mutations in TNAC and LK-TNBC. The top 16 significantly mutated genes as determined by the dNdScv algorithm (p &lt

Updated on:February 18,2024

Skin cancer rewires its energy systems to spread more efficiently, finds study

by Queen Mary, University of LondonDifferent modes of migration and mitochondrial metabolism.a,bOxygen consumption rate (OCR) from cells embedded in a 3D collagen I matrix (n = 

Updated on: February 18,2024

Skin cancer rewires its energy systems to spread more efficiently, finds study

by Queen Mary, University of LondonDifferent modes of migration and mitochondrial metabolism.a,bOxygen consumption rate (OCR) from cells embedded in a 3D collagen I matrix (n = 

Updated on:February 18,2024

Following the tumour DNA trail to crack the secrets of personalised medicine

by European Society for Medical OncologyCredit: CC0 Public DomainIndividualised therapies that target the specific genetic features of tumours have the potential to transform cancer diagnosis, tr

Updated on: April 01,2024

Following the tumour DNA trail to crack the secrets of personalised medicine

by European Society for Medical OncologyCredit: CC0 Public DomainIndividualised therapies that target the specific genetic features of tumours have the potential to transform cancer diagnosis, tr

Updated on:April 01,2024

Specialized immune cells carry potential for new cancer immunotherapies

byLeiden UniversityTumor-infiltrating Vδ1 and Vδ3 T cell subsets display hallmarks of cytotoxic activity in MMR-d colon cancers. a, UMAP embedding showing the clustering of γδ T cells (n = 4,442

Updated on: January 23,2024

Specialized immune cells carry potential for new cancer immunotherapies

byLeiden UniversityTumor-infiltrating Vδ1 and Vδ3 T cell subsets display hallmarks of cytotoxic activity in MMR-d colon cancers. a, UMAP embedding showing the clustering of γδ T cells (n = 4,442

Updated on:January 23,2024

Inhibition of histone deacetylase 2 reduces MDM2 expression and reduces tumor growth in dedifferentiated liposarcoma

by OncotargetElevated HDAC2 mRNA expression is poorly prognostic in DDLPS. (A) mRNA expression of HDAC2 and disease-free survival (DFS) data from 52 subjects with DDLPS from The Cancer Genome Atlas (T

Updated on: May 11,2024

Inhibition of histone deacetylase 2 reduces MDM2 expression and reduces tumor growth in dedifferentiated liposarcoma

by OncotargetElevated HDAC2 mRNA expression is poorly prognostic in DDLPS. (A) mRNA expression of HDAC2 and disease-free survival (DFS) data from 52 subjects with DDLPS from The Cancer Genome Atlas (T

Updated on:May 11,2024