Link between sphingolipids and complement signaling may be key to stopping cancer metastasis

by Caroline Wallace,Medical University of South CarolinaGraphical Abstract. Credit:Cell Reports(2022). DOI: 10.1016/j.celrep.2022.111742MUSC Hollings Cancer Center researchers have i

Updated on: January 02,2024

Link between sphingolipids and complement signaling may be key to stopping cancer metastasis

by Caroline Wallace,Medical University of South CarolinaGraphical Abstract. Credit:Cell Reports(2022). DOI: 10.1016/j.celrep.2022.111742MUSC Hollings Cancer Center researchers have i

Updated on:January 02,2024

Vitamin D supplementation likely improves survival of cancers of the digestive tract, says researcher

by Boston University School of MedicineCredit: Unsplash/CC0 Public DomainFor more than 100 years, it has been believed that sunlight and vitamin D deficiency were associated with the risk for man

Updated on: January 30,2024

Vitamin D supplementation likely improves survival of cancers of the digestive tract, says researcher

by Boston University School of MedicineCredit: Unsplash/CC0 Public DomainFor more than 100 years, it has been believed that sunlight and vitamin D deficiency were associated with the risk for man

Updated on:January 30,2024

Promotion of cancer progression via extracellular vesicles

by Tokyo Medical and Dental UniversityUsually, blood vessels are stabilized, and their barrier function is maintained by the tight adhesion between vascular endothelial cells (①). When cancer cells me

Updated on: January 07,2024

Promotion of cancer progression via extracellular vesicles

by Tokyo Medical and Dental UniversityUsually, blood vessels are stabilized, and their barrier function is maintained by the tight adhesion between vascular endothelial cells (①). When cancer cells me

Updated on:January 07,2024

A novel method to better predict the outgrowth of ductal carcinoma in situ

by Netherlands Cancer InstituteGraphical abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.04.002An international team of researchers led by the Netherlands Cancer Institu

Updated on: February 03,2024

A novel method to better predict the outgrowth of ductal carcinoma in situ

by Netherlands Cancer InstituteGraphical abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.04.002An international team of researchers led by the Netherlands Cancer Institu

Updated on:February 03,2024

Skin cancer rewires its energy systems to spread more efficiently, finds study

by Queen Mary, University of LondonDifferent modes of migration and mitochondrial metabolism.a,bOxygen consumption rate (OCR) from cells embedded in a 3D collagen I matrix (n = 

Updated on: February 18,2024

Skin cancer rewires its energy systems to spread more efficiently, finds study

by Queen Mary, University of LondonDifferent modes of migration and mitochondrial metabolism.a,bOxygen consumption rate (OCR) from cells embedded in a 3D collagen I matrix (n = 

Updated on:February 18,2024

Enzyme inhibition promotes bone formation and curbs the development of bone metastases, study finds

byGerman Cancer Research CenterNegative regulation of bone formation by TAM receptor MERTK.amRNA expression analysis of TAM receptor familyMertk,Tyro3,Axl,Gas

Updated on: January 23,2024

Enzyme inhibition promotes bone formation and curbs the development of bone metastases, study finds

byGerman Cancer Research CenterNegative regulation of bone formation by TAM receptor MERTK.amRNA expression analysis of TAM receptor familyMertk,Tyro3,Axl,Gas

Updated on:January 23,2024

Following the tumour DNA trail to crack the secrets of personalised medicine

by European Society for Medical OncologyCredit: CC0 Public DomainIndividualised therapies that target the specific genetic features of tumours have the potential to transform cancer diagnosis, tr

Updated on: April 01,2024

Following the tumour DNA trail to crack the secrets of personalised medicine

by European Society for Medical OncologyCredit: CC0 Public DomainIndividualised therapies that target the specific genetic features of tumours have the potential to transform cancer diagnosis, tr

Updated on:April 01,2024

Inhibition of histone deacetylase 2 reduces MDM2 expression and reduces tumor growth in dedifferentiated liposarcoma

by OncotargetElevated HDAC2 mRNA expression is poorly prognostic in DDLPS. (A) mRNA expression of HDAC2 and disease-free survival (DFS) data from 52 subjects with DDLPS from The Cancer Genome Atlas (T

Updated on: May 11,2024

Inhibition of histone deacetylase 2 reduces MDM2 expression and reduces tumor growth in dedifferentiated liposarcoma

by OncotargetElevated HDAC2 mRNA expression is poorly prognostic in DDLPS. (A) mRNA expression of HDAC2 and disease-free survival (DFS) data from 52 subjects with DDLPS from The Cancer Genome Atlas (T

Updated on:May 11,2024

New test helps drug discoverers identify future cancer treatments

byInstitute of Cancer ResearchAn illustration of how the R2KD tool works Credit: Dr Maggie Liu, first authorResearchers have developed an investigative procedure that makes the early stages of d

Updated on: January 11,2024

New test helps drug discoverers identify future cancer treatments

byInstitute of Cancer ResearchAn illustration of how the R2KD tool works Credit: Dr Maggie Liu, first authorResearchers have developed an investigative procedure that makes the early stages of d

Updated on:January 11,2024

Microbial signature of colorectal cancer-associated mutations identified

by American Society for MicrobiologyCredit: CC0 Public DomainFor about 40% of people diagnosed with colorectal cancer (CRC), the tumor carries a mutation in a gene called KRAS. Many of those muta

Updated on: April 06,2024

Microbial signature of colorectal cancer-associated mutations identified

by American Society for MicrobiologyCredit: CC0 Public DomainFor about 40% of people diagnosed with colorectal cancer (CRC), the tumor carries a mutation in a gene called KRAS. Many of those muta

Updated on:April 06,2024

Experts call for a targeted approach to cancer prevention

by University of StirlingCredit: CC0 Public DomainPolicymakers around the world should consider introducing more targeted early interventions in a bid to tackle cancer, according to experts at th

Updated on: April 07,2024

Experts call for a targeted approach to cancer prevention

by University of StirlingCredit: CC0 Public DomainPolicymakers around the world should consider introducing more targeted early interventions in a bid to tackle cancer, according to experts at th

Updated on:April 07,2024

Rethinking how cancer cells evade targeted therapy

byUniversity of California, San FranciscoA single-cell RNA atlas of human glioblastoma through recurrence.a, An overview of genomics studies on paired longitudinal GBM specimens.b, A

Updated on: January 22,2024

Rethinking how cancer cells evade targeted therapy

byUniversity of California, San FranciscoA single-cell RNA atlas of human glioblastoma through recurrence.a, An overview of genomics studies on paired longitudinal GBM specimens.b, A

Updated on:January 22,2024