Immunotherapy was meant to defeat cancer—what happened to the great promise?

by Jonathan Fisher,The ConversationCredit: Ivan Samkov from PexelsIn 1893, theAmerican Journal of the Medical Sciencesreported on 10 patients whose large and hitherto incurable cance

Updated on: November 10,2024

Immunotherapy was meant to defeat cancer—what happened to the great promise?

by Jonathan Fisher,The ConversationCredit: Ivan Samkov from PexelsIn 1893, theAmerican Journal of the Medical Sciencesreported on 10 patients whose large and hitherto incurable cance

Updated on:November 10,2024

A novel method to better predict the outgrowth of ductal carcinoma in situ

by Netherlands Cancer InstituteGraphical abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.04.002An international team of researchers led by the Netherlands Cancer Institu

Updated on: February 03,2024

A novel method to better predict the outgrowth of ductal carcinoma in situ

by Netherlands Cancer InstituteGraphical abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.04.002An international team of researchers led by the Netherlands Cancer Institu

Updated on:February 03,2024

Minorities face longer wait times for vital lung cancer treatment, study finds

byUniversity of VirginiaCredit: Pixabay/CC0 Public DomainA new study has revealed significant racial disparities in how quickly minorities with the most common form of lung cancer receive potent

Updated on: January 23,2024

Minorities face longer wait times for vital lung cancer treatment, study finds

byUniversity of VirginiaCredit: Pixabay/CC0 Public DomainA new study has revealed significant racial disparities in how quickly minorities with the most common form of lung cancer receive potent

Updated on:January 23,2024

Peripheral surrogates of tumor burden to guide therapeutic strategies for HPV-associated malignancies

by Impact Journals LLCTumor intrinsic and extrinsic factors in the periphery that can serve as proxies of tumor burden. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28487A new review

Updated on: January 22,2024

Peripheral surrogates of tumor burden to guide therapeutic strategies for HPV-associated malignancies

by Impact Journals LLCTumor intrinsic and extrinsic factors in the periphery that can serve as proxies of tumor burden. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28487A new review

Updated on:January 22,2024

Shortage of vital children's cancer drug stirs fear and outrage

by Marie McCulloughCredit: CC0 Public DomainA critical shortage of a chemotherapy used to treat most childhood cancers has galvanized oncologists and parents of sick children.The U.S.medical com

Updated on: April 07,2024

Shortage of vital children's cancer drug stirs fear and outrage

by Marie McCulloughCredit: CC0 Public DomainA critical shortage of a chemotherapy used to treat most childhood cancers has galvanized oncologists and parents of sick children.The U.S.medical com

Updated on:April 07,2024

Resistance of mammary fibrosis to immune checkpoint therapy linked to macrophage infiltration, Wnt pathway expression

by Impact Journals LLCWnt pathway expression in tumors from NeuT/ATTAC mice. Credit: 2022 Yuan et al.A new research paper titled "Resistance of MMTV-NeuT/ATTAC mice to anti-PD-1 immune checkpoint

Updated on: January 03,2024

Resistance of mammary fibrosis to immune checkpoint therapy linked to macrophage infiltration, Wnt pathway expression

by Impact Journals LLCWnt pathway expression in tumors from NeuT/ATTAC mice. Credit: 2022 Yuan et al.A new research paper titled "Resistance of MMTV-NeuT/ATTAC mice to anti-PD-1 immune checkpoint

Updated on:January 03,2024

Research identifies a new drug candidate to starve and suffocate breast cancer cell stem growth

by University of SalfordMichael P. Lisanti. Credit: University of SalfordScientists have identified a new drug candidate that is able starve and suffocate cancer stem cells, paving the way for ne

Updated on: June 28,2024

Research identifies a new drug candidate to starve and suffocate breast cancer cell stem growth

by University of SalfordMichael P. Lisanti. Credit: University of SalfordScientists have identified a new drug candidate that is able starve and suffocate cancer stem cells, paving the way for ne

Updated on:June 28,2024

Depression linked to deadly inflammation in lung cancer patients

by Jeff Grabmeier,The Ohio State UniversityKaplan Meier survival curve for NSCLC patients stratified by NLR systemic inflammation, NLR < 5 and NLR ≥ 5 (n = 184), showing worse survival probab

Updated on: January 30,2024

Depression linked to deadly inflammation in lung cancer patients

by Jeff Grabmeier,The Ohio State UniversityKaplan Meier survival curve for NSCLC patients stratified by NLR systemic inflammation, NLR < 5 and NLR ≥ 5 (n = 184), showing worse survival probab

Updated on:January 30,2024

An unexpected journey reveals a potent way to attack tumors

by Nancy Fliesler,Children's Hospital BostonSenescence inducer CuSO4, which causes ER stress, activates NKp46- and NKG2D-dependent NK killing, but 4-PBA, which induces senescence without ER

Updated on: February 23,2024

An unexpected journey reveals a potent way to attack tumors

by Nancy Fliesler,Children's Hospital BostonSenescence inducer CuSO4, which causes ER stress, activates NKp46- and NKG2D-dependent NK killing, but 4-PBA, which induces senescence without ER

Updated on:February 23,2024

Novel genomics tool enables more accurate identification of rare mutations in cancer cells

by New York Genome CenterExample of colored de Bruijn graph rendered to represent genomic data for a short region of 400 base pairs using the Lancet genomics tool developed by New York Genome Center s

Updated on: March 01,2024

Novel genomics tool enables more accurate identification of rare mutations in cancer cells

by New York Genome CenterExample of colored de Bruijn graph rendered to represent genomic data for a short region of 400 base pairs using the Lancet genomics tool developed by New York Genome Center s

Updated on:March 01,2024

Novel AI tools tackle soft tissue sarcomas, identify new treatment strategies

byStanford University Medical CenterA machine-learning framework for large-scale identification and validation of sarcoma cell states and ecosystems. Credit:Nature Cancer(2024). DOI:

Updated on: March 30,2024

Novel AI tools tackle soft tissue sarcomas, identify new treatment strategies

byStanford University Medical CenterA machine-learning framework for large-scale identification and validation of sarcoma cell states and ecosystems. Credit:Nature Cancer(2024). DOI:

Updated on:March 30,2024

Team reveals specific mechanism for promoting cancer vulnerability to ferroptosis

by Luisa Hoffmann,Helmholtz Association of German Research CentresCredit: Pixabay/CC0 Public DomainA research team at Helmholtz Munich has revealed a specific mechanism that is able to promote c

Updated on: January 30,2024

Team reveals specific mechanism for promoting cancer vulnerability to ferroptosis

by Luisa Hoffmann,Helmholtz Association of German Research CentresCredit: Pixabay/CC0 Public DomainA research team at Helmholtz Munich has revealed a specific mechanism that is able to promote c

Updated on:January 30,2024