An unexpected journey reveals a potent way to attack tumors

by Nancy Fliesler,Children's Hospital BostonSenescence inducer CuSO4, which causes ER stress, activates NKp46- and NKG2D-dependent NK killing, but 4-PBA, which induces senescence without ER

Updated on: February 23,2024

An unexpected journey reveals a potent way to attack tumors

by Nancy Fliesler,Children's Hospital BostonSenescence inducer CuSO4, which causes ER stress, activates NKp46- and NKG2D-dependent NK killing, but 4-PBA, which induces senescence without ER

Updated on:February 23,2024

Diverse immune cell profiles and roles found in breast cancer resistance to immunotherapy

by Baylor College of MedicineDr. Xiang 'Shawn' Zhang, the corresponding author of this work. Credit: Baylor College of MedicineIn recent years it has been increasingly appreciated that im

Updated on: April 22,2024

Diverse immune cell profiles and roles found in breast cancer resistance to immunotherapy

by Baylor College of MedicineDr. Xiang 'Shawn' Zhang, the corresponding author of this work. Credit: Baylor College of MedicineIn recent years it has been increasingly appreciated that im

Updated on:April 22,2024

Allogeneic hematopoietic cell transplant outcomes improved from 2005 to 2019: Study

by Lori SolomonOutcomes of allogeneic hematopoietic cell transplantation (allo-HCT) in patients with acute myeloid leukemia (AML) and second complete remission (CR2) have significantly improved over t

Updated on: February 18,2024

Allogeneic hematopoietic cell transplant outcomes improved from 2005 to 2019: Study

by Lori SolomonOutcomes of allogeneic hematopoietic cell transplantation (allo-HCT) in patients with acute myeloid leukemia (AML) and second complete remission (CR2) have significantly improved over t

Updated on:February 18,2024

Researchers customize top-of-the-line microscopy method with AI to better understand glioblastoma tumors

byEuropean Molecular Biology LaboratoryRationale and combined experimental/analysis pipeline for deep brain tumor imaging. Credit:Nature Communications(2024). DOI:10.1038/s41467-024-

Updated on: September 28,2024

Researchers customize top-of-the-line microscopy method with AI to better understand glioblastoma tumors

byEuropean Molecular Biology LaboratoryRationale and combined experimental/analysis pipeline for deep brain tumor imaging. Credit:Nature Communications(2024). DOI:10.1038/s41467-024-

Updated on:September 28,2024

Immunotherapy was meant to defeat cancer—what happened to the great promise?

by Jonathan Fisher,The ConversationCredit: Ivan Samkov from PexelsIn 1893, theAmerican Journal of the Medical Sciencesreported on 10 patients whose large and hitherto incurable cance

Updated on: November 10,2024

Immunotherapy was meant to defeat cancer—what happened to the great promise?

by Jonathan Fisher,The ConversationCredit: Ivan Samkov from PexelsIn 1893, theAmerican Journal of the Medical Sciencesreported on 10 patients whose large and hitherto incurable cance

Updated on:November 10,2024

Two drugs are better than one in fight against leukaemia

by FreshscienceDr Laura Eadie at work in the SAHMRI Leukaemia Research Laboratory. Credit: SAHMRIAdelaide scientists have devised a way to enhance the effectiveness of a patient's leukaemia treatm

Updated on: April 20,2024

Two drugs are better than one in fight against leukaemia

by FreshscienceDr Laura Eadie at work in the SAHMRI Leukaemia Research Laboratory. Credit: SAHMRIAdelaide scientists have devised a way to enhance the effectiveness of a patient's leukaemia treatm

Updated on:April 20,2024

On a stretch of gravel road, families ravaged by cancer question nitrate

by Jennifer Bjorhus, Star TribuneCredit: Unsplash/CC0 Public DomainCancer ravaged Brian Bennerotte's body and those of many around him—his father, five brothers and his sister—as well as others al

Updated on: April 20,2024

On a stretch of gravel road, families ravaged by cancer question nitrate

by Jennifer Bjorhus, Star TribuneCredit: Unsplash/CC0 Public DomainCancer ravaged Brian Bennerotte's body and those of many around him—his father, five brothers and his sister—as well as others al

Updated on:April 20,2024

New method predicts the right treatment for breast cancer patients

byKarolinska InstitutetThe researchers developed and tested whole-tumor cell culture models derived from breast cancer patients that can predict how the tumors will respond to different treatmen

Updated on: January 13,2024

New method predicts the right treatment for breast cancer patients

byKarolinska InstitutetThe researchers developed and tested whole-tumor cell culture models derived from breast cancer patients that can predict how the tumors will respond to different treatmen

Updated on:January 13,2024

Researchers identify key metabolic regulators of drug resistance in the fight against pancreatic cancer

by Rebecca Brierley,University at BuffaloGraphical abstract. Credit:Molecular & Cellular Proteomics(2022). DOI: 10.1016/j.mcpro.2022.100409Researchers from the University at Buff

Updated on: February 20,2024

Researchers identify key metabolic regulators of drug resistance in the fight against pancreatic cancer

by Rebecca Brierley,University at BuffaloGraphical abstract. Credit:Molecular & Cellular Proteomics(2022). DOI: 10.1016/j.mcpro.2022.100409Researchers from the University at Buff

Updated on:February 20,2024

A machine learning-based algorithm to predict which cancer patients benefit from immunotherapy

by Institute for Research in Biomedicine (IRB Barcelona)Credit: CC0 Public DomainScientists at the Institute for Research in Biomedicine (IRB Barcelona), in collaboration with the Centre for Geno

Updated on: May 20,2024

A machine learning-based algorithm to predict which cancer patients benefit from immunotherapy

by Institute for Research in Biomedicine (IRB Barcelona)Credit: CC0 Public DomainScientists at the Institute for Research in Biomedicine (IRB Barcelona), in collaboration with the Centre for Geno

Updated on:May 20,2024

Study illuminates precancerous 'clonal outgrowth' in blood cells

byWeill Cornell Medical CollegeCredit: CC0 Public DomainA common, spontaneous mutation in blood stem cells, which has been linked to higher risks of blood cancer and cardiovascular disease, may

Updated on: January 22,2024

Study illuminates precancerous 'clonal outgrowth' in blood cells

byWeill Cornell Medical CollegeCredit: CC0 Public DomainA common, spontaneous mutation in blood stem cells, which has been linked to higher risks of blood cancer and cardiovascular disease, may

Updated on:January 22,2024

Researchers suggest new way to target third most common oncogene, TERT

by Garth Sundem,CU Anschutz Medical CampusChromosome, showing telomeres in pink. Credit: CUHealthy cells have a built-in self-destruct mechanism: Strands of DNA called "telomeres" act

Updated on: March 01,2024

Researchers suggest new way to target third most common oncogene, TERT

by Garth Sundem,CU Anschutz Medical CampusChromosome, showing telomeres in pink. Credit: CUHealthy cells have a built-in self-destruct mechanism: Strands of DNA called "telomeres" act

Updated on:March 01,2024