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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
Sub Categories on Oncology
Latest Articles
Study validates clinical utility of pan-tumor predictive biomarker for checkpoint inhibitor immunotherapy benefit

Study validates clinical utility of pan-tumor predictive biomarker for checkpoint inhibitor immunotherapy benefit

by Strata OncologyDevelopment of an integrative immunotherapy response score (IRS) model to stratify PD-(L)1 therapy benefit in patients with advanced solid tumors.aReal-world treatment an

Study validates clinical utility of pan-tumor predictive biomarker for checkpoint inhibitor immunotherapy benefit

by Strata OncologyDevelopment of an integrative immunotherapy response score (IRS) model to stratify PD-(L)1 therapy benefit in patients with advanced solid tumors.aReal-world treatment an
New method eradicates deadly brain tumors by 'starving' them of energy source

New method eradicates deadly brain tumors by 'starving' them of energy source

byTel Aviv UniversityDr. Lior Mayo and students. Credit: Tel Aviv UniversityA groundbreaking study at Tel Aviv University effectively eradicated glioblastoma, a highly lethal type of brain cance

New method eradicates deadly brain tumors by 'starving' them of energy source

byTel Aviv UniversityDr. Lior Mayo and students. Credit: Tel Aviv UniversityA groundbreaking study at Tel Aviv University effectively eradicated glioblastoma, a highly lethal type of brain cance
Researchers identify cell signaling pathways controlling melanoma cell metastasis to the brain

Researchers identify cell signaling pathways controlling melanoma cell metastasis to the brain

by H. Lee Moffitt Cancer Center & Research InstituteHDAC8 increases the establishment of melanoma brain metastases.a–cHDAC8 and EV expressing WM164 cells were introduced into NOD.

Researchers identify cell signaling pathways controlling melanoma cell metastasis to the brain

by H. Lee Moffitt Cancer Center & Research InstituteHDAC8 increases the establishment of melanoma brain metastases.a–cHDAC8 and EV expressing WM164 cells were introduced into NOD.
Researchers identify mechanism of resistance to BRAF inhibitors in melanoma

Researchers identify mechanism of resistance to BRAF inhibitors in melanoma

by H. Lee Moffitt Cancer Center & Research InstituteMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Melanoma i

Researchers identify mechanism of resistance to BRAF inhibitors in melanoma

by H. Lee Moffitt Cancer Center & Research InstituteMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Melanoma i
Ancient viruses could help kill cancers

Ancient viruses could help kill cancers

by The Francis Crick InstituteHeatmap showing expression of melanoma-specific transcripts across a range of cancer types. The three columns with high expression are from melanoma samples. Credit:

Ancient viruses could help kill cancers

by The Francis Crick InstituteHeatmap showing expression of melanoma-specific transcripts across a range of cancer types. The three columns with high expression are from melanoma samples. Credit:
Synthetic molecule proves able to mitigate heart failure in translational study

Synthetic molecule proves able to mitigate heart failure in translational study

by Maria Fernanda Ziegler,FAPESPThe vicious cycle of heart failure (HF). (i) Impaired aldehyde metabolism by aldehyde dehydrogenase 2 (ALDH2); (ii) accumulation of 4-hydroxynonenal (4-HNE), a re

Synthetic molecule proves able to mitigate heart failure in translational study

by Maria Fernanda Ziegler,FAPESPThe vicious cycle of heart failure (HF). (i) Impaired aldehyde metabolism by aldehyde dehydrogenase 2 (ALDH2); (ii) accumulation of 4-hydroxynonenal (4-HNE), a re
A new strategy 'raises the volume' of gut-body communication

A new strategy 'raises the volume' of gut-body communication

by Ana María Rodríguez, Ph.d.,Baylor College of MedicineCredit: CC0 Public DomainThroughout the gastrointestinal tract there are specialized hormone-producing cells called enteroendocrine cells

A new strategy 'raises the volume' of gut-body communication

by Ana María Rodríguez, Ph.d.,Baylor College of MedicineCredit: CC0 Public DomainThroughout the gastrointestinal tract there are specialized hormone-producing cells called enteroendocrine cells
Previously unidentified proteins suggest new way to diagnose ovarian cancer

Previously unidentified proteins suggest new way to diagnose ovarian cancer

by Nagoya UniversityExtracellular vesicles (EVs) are vesicles with lipid-bilayer structures (shown in center), and three proteins expressed on small EVs called exosomes (shown in red, green, blue

Previously unidentified proteins suggest new way to diagnose ovarian cancer

by Nagoya UniversityExtracellular vesicles (EVs) are vesicles with lipid-bilayer structures (shown in center), and three proteins expressed on small EVs called exosomes (shown in red, green, blue
The impact of cohesin mutations: Insights into a hidden regulator of alternative splicing in leukemia

The impact of cohesin mutations: Insights into a hidden regulator of alternative splicing in leukemia

by Justin Jackson , Medical XpressCohesin regulates alternative splicing. (A) Flowchart showing the experimental protocol, as detailed in Materials and Methods. (B) Schematic showing five different cl

The impact of cohesin mutations: Insights into a hidden regulator of alternative splicing in leukemia

by Justin Jackson , Medical XpressCohesin regulates alternative splicing. (A) Flowchart showing the experimental protocol, as detailed in Materials and Methods. (B) Schematic showing five different cl
Revealing characteristics of circulating cell-free RNA in the blood of liver cancer patients

Revealing characteristics of circulating cell-free RNA in the blood of liver cancer patients

byScience China PressMOF materials efficiently enrich circulating nucleic acids (cfDNA and cfRNA) in blood through a simple operational process, enabling various downstream nucleic acid detectio

Revealing characteristics of circulating cell-free RNA in the blood of liver cancer patients

byScience China PressMOF materials efficiently enrich circulating nucleic acids (cfDNA and cfRNA) in blood through a simple operational process, enabling various downstream nucleic acid detectio
Study discovers tumor monocyte content predicts immunochemotherapy outcomes for esophageal cancer

Study discovers tumor monocyte content predicts immunochemotherapy outcomes for esophageal cancer

by Ludwig Institute for Cancer ResearchGraphical Abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.06.006A Ludwig Cancer Research study has discovered that the presence of

Study discovers tumor monocyte content predicts immunochemotherapy outcomes for esophageal cancer

by Ludwig Institute for Cancer ResearchGraphical Abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.06.006A Ludwig Cancer Research study has discovered that the presence of
BMI's relation to cancer therapy mortality risks not so straightforward, study finds

BMI's relation to cancer therapy mortality risks not so straightforward, study finds

byOsaka Metropolitan UniversityFor non-small cell lung cancer treatment, immunotherapy seems to pose less risk for persons under a certain BMI, while conventional chemotherapy appears optimal fo

BMI's relation to cancer therapy mortality risks not so straightforward, study finds

byOsaka Metropolitan UniversityFor non-small cell lung cancer treatment, immunotherapy seems to pose less risk for persons under a certain BMI, while conventional chemotherapy appears optimal fo