Study uncovers epigenetic source of resistance to targeted therapy in EGFR-mutant lung cancer

by Dana-Farber Cancer InstituteCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.07.005When lung cancers driven by mutations in the EGFR gene become resistant to osimertinib or othe

Updated on: February 01,2024

Study uncovers epigenetic source of resistance to targeted therapy in EGFR-mutant lung cancer

by Dana-Farber Cancer InstituteCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.07.005When lung cancers driven by mutations in the EGFR gene become resistant to osimertinib or othe

Updated on:February 01,2024

Inhibition of ribosome biogenesis as a novel approach for multi-stage cancer treatment

by Uppsala UniversityCredit: Uppsala UniversityNearly 90 percent of all cancer patient deaths are due to metastasis. A study from Uppsala University shows that a process that allows the cells to

Updated on: May 11,2024

Inhibition of ribosome biogenesis as a novel approach for multi-stage cancer treatment

by Uppsala UniversityCredit: Uppsala UniversityNearly 90 percent of all cancer patient deaths are due to metastasis. A study from Uppsala University shows that a process that allows the cells to

Updated on:May 11,2024

Young women often delay looking into breast symptoms, research finds

by Dennis ThompsonYoung women who find a lump or other potential signs of breast cancer often delay for weeks before finally seeing a doctor, a new study shows.On average, young women waited two weeks

Updated on: April 28,2024

Young women often delay looking into breast symptoms, research finds

by Dennis ThompsonYoung women who find a lump or other potential signs of breast cancer often delay for weeks before finally seeing a doctor, a new study shows.On average, young women waited two weeks

Updated on:April 28,2024

Genomic deletions explain why some types of melanoma resist targeted therapies

byCenter for Genomic RegulationCredit: CC0 Public DomainMelanoma is the deadliest form of skin cancer. With global incidence rates rising, new, more effective treatments are necessary to allevia

Updated on: April 28,2024

Genomic deletions explain why some types of melanoma resist targeted therapies

byCenter for Genomic RegulationCredit: CC0 Public DomainMelanoma is the deadliest form of skin cancer. With global incidence rates rising, new, more effective treatments are necessary to allevia

Updated on:April 28,2024

Killing pancreatic cancer with T cells that supercharge themselves

by University of California, San FranciscoTherapeutic T cells engineered with tumor-triggered IL-2 production infiltrate and clear immune-excluded tumors. (A) We hypothesized that cell autonomous

Updated on: February 18,2024

Killing pancreatic cancer with T cells that supercharge themselves

by University of California, San FranciscoTherapeutic T cells engineered with tumor-triggered IL-2 production infiltrate and clear immune-excluded tumors. (A) We hypothesized that cell autonomous

Updated on:February 18,2024

Investigators build a better targeted drug therapy using the power of computation

by Brigham and Women's HospitalCancer cell during cell division. Credit: National Institutes of HealthAntibody drug conjugates (ADCs)—cancer drugs that are designed to target and destroy canc

Updated on: June 08,2024

Investigators build a better targeted drug therapy using the power of computation

by Brigham and Women's HospitalCancer cell during cell division. Credit: National Institutes of HealthAntibody drug conjugates (ADCs)—cancer drugs that are designed to target and destroy canc

Updated on:June 08,2024

The sugar-attaching enzyme that defines colon cancer

by American Society for Biochemistry and Molecular BiologyThe enzyme GalNAc-T6 is selectively up-regulated in colon adenocarcinomas, and its expression is associated with a cancer-like growth pat

Updated on: April 14,2024

The sugar-attaching enzyme that defines colon cancer

by American Society for Biochemistry and Molecular BiologyThe enzyme GalNAc-T6 is selectively up-regulated in colon adenocarcinomas, and its expression is associated with a cancer-like growth pat

Updated on:April 14,2024

Study: Drugs reprogram genes in breast tumors to prevent endocrine resistance

by Sharita Forrest,University of Illinois at Urbana-ChampaignTargeting estrogen receptor-positive breast tumors with the XPO1 antagonist selinexor and the tamoxifen byproduct 4-OHT simultaneousl

Updated on: May 27,2024

Study: Drugs reprogram genes in breast tumors to prevent endocrine resistance

by Sharita Forrest,University of Illinois at Urbana-ChampaignTargeting estrogen receptor-positive breast tumors with the XPO1 antagonist selinexor and the tamoxifen byproduct 4-OHT simultaneousl

Updated on:May 27,2024

Researcher: Big data, networks identify cell signaling pathways in lung cancer

by University of MontanaThe cover of the May 22 issue ofScience Signalingfeatures a three-dimensional representation of lung cancer protein modifications produced by the machine learn

Updated on: June 24,2024

Researcher: Big data, networks identify cell signaling pathways in lung cancer

by University of MontanaThe cover of the May 22 issue ofScience Signalingfeatures a three-dimensional representation of lung cancer protein modifications produced by the machine learn

Updated on:June 24,2024

Scientists advise caution in immunotherapy research

by Yale UniversityCredit: CC0 Public DomainIn a new study, Yale Cancer Center (YCC) scientists suggest that as the number of clinical trials in cancer immunotherapy grows exponentially, some caut

Updated on: March 06,2024

Scientists advise caution in immunotherapy research

by Yale UniversityCredit: CC0 Public DomainIn a new study, Yale Cancer Center (YCC) scientists suggest that as the number of clinical trials in cancer immunotherapy grows exponentially, some caut

Updated on:March 06,2024

Can diet help cancer treatment? Study in mice offers clues

by Sara HusseinA study in the journalNaturefound that restricting the intake of an amino acid found in red meat and eggs slowed the growth of cancerous tumours in miceDiet is already a key

Updated on: May 11,2024

Can diet help cancer treatment? Study in mice offers clues

by Sara HusseinA study in the journalNaturefound that restricting the intake of an amino acid found in red meat and eggs slowed the growth of cancerous tumours in miceDiet is already a key

Updated on:May 11,2024

Biological pathways provide evidence for how to overcome barriers limiting cancer immunotherapies

byUNC Lineberger Comprehensive Cancer CenterCredit: Unsplash/CC0 Public DomainResearchers at UNC Lineberger Comprehensive Cancer Center have found a possible way to overcome barriers that block

Updated on: January 04,2024

Biological pathways provide evidence for how to overcome barriers limiting cancer immunotherapies

byUNC Lineberger Comprehensive Cancer CenterCredit: Unsplash/CC0 Public DomainResearchers at UNC Lineberger Comprehensive Cancer Center have found a possible way to overcome barriers that block

Updated on:January 04,2024