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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Mapping lactylome in hepatocellular carcinoma reveals new mechanisms of metabolic adaptation

Mapping lactylome in hepatocellular carcinoma reveals new mechanisms of metabolic adaptation

by Liu Jia,Chinese Academy of SciencesCredit: Pixabay/CC0 Public DomainLactate, a major product of glycolysis in mammals, is significantly increased in pathological states such as tumors, sepsis

Mapping lactylome in hepatocellular carcinoma reveals new mechanisms of metabolic adaptation

by Liu Jia,Chinese Academy of SciencesCredit: Pixabay/CC0 Public DomainLactate, a major product of glycolysis in mammals, is significantly increased in pathological states such as tumors, sepsis
Researchers identify key metabolic regulators of drug resistance in the fight against pancreatic cancer

Researchers identify key metabolic regulators of drug resistance in the fight against pancreatic cancer

by Rebecca Brierley,University at BuffaloGraphical abstract. Credit:Molecular & Cellular Proteomics(2022). DOI: 10.1016/j.mcpro.2022.100409Researchers from the University at Buff

Researchers identify key metabolic regulators of drug resistance in the fight against pancreatic cancer

by Rebecca Brierley,University at BuffaloGraphical abstract. Credit:Molecular & Cellular Proteomics(2022). DOI: 10.1016/j.mcpro.2022.100409Researchers from the University at Buff
DDX41 and its unique contribution to myeloid leukemogenesis

DDX41 and its unique contribution to myeloid leukemogenesis

by Impact Journals LLCCredit: Unsplash/CC0 Public DomainIn an editorial paper published inOncotargettitled, "DDX41 and its unique contribution to myeloid leukemogenesis," researc

DDX41 and its unique contribution to myeloid leukemogenesis

by Impact Journals LLCCredit: Unsplash/CC0 Public DomainIn an editorial paper published inOncotargettitled, "DDX41 and its unique contribution to myeloid leukemogenesis," researc
An accurate integrated imaging and projection system for oral cancer diagnosis

An accurate integrated imaging and projection system for oral cancer diagnosis

by SPIEImaging workflow of the ABGS. Step 1: widefield images are acquired using the camera and projector. Step 2: a cancer risk map is generated and projected onto the oral cavity. Step 3: multi

An accurate integrated imaging and projection system for oral cancer diagnosis

by SPIEImaging workflow of the ABGS. Step 1: widefield images are acquired using the camera and projector. Step 2: a cancer risk map is generated and projected onto the oral cavity. Step 3: multi
Tumour removal with a cancer cell clear margin

Tumour removal with a cancer cell clear margin

by CORDISCredit: Benjamin Franklin PierceA biopsy reporting that cancer cells are still in the margin indicates a likelihood of cancer cells remaining in the body. An EU-funded project, IMAGINE,

Tumour removal with a cancer cell clear margin

by CORDISCredit: Benjamin Franklin PierceA biopsy reporting that cancer cells are still in the margin indicates a likelihood of cancer cells remaining in the body. An EU-funded project, IMAGINE,
Study: Immunotherapy costs drive increase in Medicare spending for outpatient cancer care at the end of life

Study: Immunotherapy costs drive increase in Medicare spending for outpatient cancer care at the end of life

by American Society for Radiation OncologyCredit: Pixabay/CC0 Public DomainA new study finds that recent increases in Medicare spending on outpatient cancer care at the end of patients' lives

Study: Immunotherapy costs drive increase in Medicare spending for outpatient cancer care at the end of life

by American Society for Radiation OncologyCredit: Pixabay/CC0 Public DomainA new study finds that recent increases in Medicare spending on outpatient cancer care at the end of patients' lives
Novel genomics tool enables more accurate identification of rare mutations in cancer cells

Novel genomics tool enables more accurate identification of rare mutations in cancer cells

by New York Genome CenterExample of colored de Bruijn graph rendered to represent genomic data for a short region of 400 base pairs using the Lancet genomics tool developed by New York Genome Center s

Novel genomics tool enables more accurate identification of rare mutations in cancer cells

by New York Genome CenterExample of colored de Bruijn graph rendered to represent genomic data for a short region of 400 base pairs using the Lancet genomics tool developed by New York Genome Center s
Researchers show that using a tumor's own bacteria is a promising anticancer therapy

Researchers show that using a tumor's own bacteria is a promising anticancer therapy

by Japan Advanced Institute of Science and TechnologyA bacterial consortium consisting of A-gyo, UN-gyo, and AUN has high anticancer efficacy, triggering the immune system to attack tumor cells. Credi

Researchers show that using a tumor's own bacteria is a promising anticancer therapy

by Japan Advanced Institute of Science and TechnologyA bacterial consortium consisting of A-gyo, UN-gyo, and AUN has high anticancer efficacy, triggering the immune system to attack tumor cells. Credi
The impact of cohesin mutations: Insights into a hidden regulator of alternative splicing in leukemia

The impact of cohesin mutations: Insights into a hidden regulator of alternative splicing in leukemia

by Justin Jackson , Medical XpressCohesin regulates alternative splicing. (A) Flowchart showing the experimental protocol, as detailed in Materials and Methods. (B) Schematic showing five different cl

The impact of cohesin mutations: Insights into a hidden regulator of alternative splicing in leukemia

by Justin Jackson , Medical XpressCohesin regulates alternative splicing. (A) Flowchart showing the experimental protocol, as detailed in Materials and Methods. (B) Schematic showing five different cl
Researchers identify markers of chemotherapy resistance and outcome in triple negative breast cancer

Researchers identify markers of chemotherapy resistance and outcome in triple negative breast cancer

by Molly Chiu,Baylor College of MedicineCredit: Unsplash/CC0 Public DomainResearchers at Baylor College of Medicine and the Broad Institute of MIT and Harvard and clinicians at Washington Univer

Researchers identify markers of chemotherapy resistance and outcome in triple negative breast cancer

by Molly Chiu,Baylor College of MedicineCredit: Unsplash/CC0 Public DomainResearchers at Baylor College of Medicine and the Broad Institute of MIT and Harvard and clinicians at Washington Univer
Study offers way to increase immune checkpoint inhibitor effectiveness in patients with MTAP-deleted cancers

Study offers way to increase immune checkpoint inhibitor effectiveness in patients with MTAP-deleted cancers

by Dana-Farber Cancer InstituteGraphical abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.09.005Loss of the "housekeeping" gene methylthioadenosine phosphorylas

Study offers way to increase immune checkpoint inhibitor effectiveness in patients with MTAP-deleted cancers

by Dana-Farber Cancer InstituteGraphical abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.09.005Loss of the "housekeeping" gene methylthioadenosine phosphorylas
Some cancer immunotherapy treatments may damage fertility

Some cancer immunotherapy treatments may damage fertility

by Monash UniversityCredit: Pixabay/CC0 Public DomainResearchers have discovered that some immunotherapy treatments used to treat cancer can cause fertility damage.It means these treatments could

Some cancer immunotherapy treatments may damage fertility

by Monash UniversityCredit: Pixabay/CC0 Public DomainResearchers have discovered that some immunotherapy treatments used to treat cancer can cause fertility damage.It means these treatments could