Killing pancreatic cancer with T cells that supercharge themselves

by University of California, San FranciscoTherapeutic T cells engineered with tumor-triggered IL-2 production infiltrate and clear immune-excluded tumors. (A) We hypothesized that cell autonomous

Updated on: February 18,2024

Killing pancreatic cancer with T cells that supercharge themselves

by University of California, San FranciscoTherapeutic T cells engineered with tumor-triggered IL-2 production infiltrate and clear immune-excluded tumors. (A) We hypothesized that cell autonomous

Updated on:February 18,2024

Depression linked to deadly inflammation in lung cancer patients

by Jeff Grabmeier,The Ohio State UniversityKaplan Meier survival curve for NSCLC patients stratified by NLR systemic inflammation, NLR < 5 and NLR ≥ 5 (n = 184), showing worse survival probab

Updated on: January 30,2024

Depression linked to deadly inflammation in lung cancer patients

by Jeff Grabmeier,The Ohio State UniversityKaplan Meier survival curve for NSCLC patients stratified by NLR systemic inflammation, NLR < 5 and NLR ≥ 5 (n = 184), showing worse survival probab

Updated on:January 30,2024

The protein behind immunotherapy resistance

byEcole Polytechnique Federale de LausanneTumor with FMRP-deficient cancer cells (in green) being infiltrated and attached by killer (CD8) T cells. Credit: Jeremy Guillot (Hanahan Lab – EPFL).Im

Updated on: January 02,2024

The protein behind immunotherapy resistance

byEcole Polytechnique Federale de LausanneTumor with FMRP-deficient cancer cells (in green) being infiltrated and attached by killer (CD8) T cells. Credit: Jeremy Guillot (Hanahan Lab – EPFL).Im

Updated on:January 02,2024

Scientists advise caution in immunotherapy research

by Yale UniversityCredit: CC0 Public DomainIn a new study, Yale Cancer Center (YCC) scientists suggest that as the number of clinical trials in cancer immunotherapy grows exponentially, some caut

Updated on: March 06,2024

Scientists advise caution in immunotherapy research

by Yale UniversityCredit: CC0 Public DomainIn a new study, Yale Cancer Center (YCC) scientists suggest that as the number of clinical trials in cancer immunotherapy grows exponentially, some caut

Updated on:March 06,2024

Researchers study how altered protein degradation contributes to the development of tumors

by Institute for Research in Biomedicine (IRB Barcelona)To ensure adequate levels of proteins in the cell, a strict quality control system is responsible for tagging the proteins with ubiquitin f

Updated on: March 06,2024

Researchers study how altered protein degradation contributes to the development of tumors

by Institute for Research in Biomedicine (IRB Barcelona)To ensure adequate levels of proteins in the cell, a strict quality control system is responsible for tagging the proteins with ubiquitin f

Updated on:March 06,2024

Tumor-induced B cell changes reveal potential biomarker for treatment response in triple negative breast cancer

byBaylor College of MedicineCredit: Pixabay/CC0 Public DomainResearchers at Baylor College of Medicine and collaborating institutions have discovered new insights into tumor-induced B cell chang

Updated on: September 28,2024

Tumor-induced B cell changes reveal potential biomarker for treatment response in triple negative breast cancer

byBaylor College of MedicineCredit: Pixabay/CC0 Public DomainResearchers at Baylor College of Medicine and collaborating institutions have discovered new insights into tumor-induced B cell chang

Updated on:September 28,2024

Researchers customize top-of-the-line microscopy method with AI to better understand glioblastoma tumors

byEuropean Molecular Biology LaboratoryRationale and combined experimental/analysis pipeline for deep brain tumor imaging. Credit:Nature Communications(2024). DOI:10.1038/s41467-024-

Updated on: September 28,2024

Researchers customize top-of-the-line microscopy method with AI to better understand glioblastoma tumors

byEuropean Molecular Biology LaboratoryRationale and combined experimental/analysis pipeline for deep brain tumor imaging. Credit:Nature Communications(2024). DOI:10.1038/s41467-024-

Updated on:September 28,2024

Cis-regulatory sequences indicative of nasopharyngeal carcinoma risk identified

by Justin Jackson , Medical XpressCredit:The American Journal of Human Genetics(2023). DOI: 10.1016/j.ajhg.2023.06.003Research led by the Sun Yat-sen University Cancer Center in China has

Updated on: February 01,2024

Cis-regulatory sequences indicative of nasopharyngeal carcinoma risk identified

by Justin Jackson , Medical XpressCredit:The American Journal of Human Genetics(2023). DOI: 10.1016/j.ajhg.2023.06.003Research led by the Sun Yat-sen University Cancer Center in China has

Updated on:February 01,2024

Even with multiple breast tumors, mastectomy isn't always necessary: Study

by Denise MannSome women with multiple breast tumors can safely be spared breast removal surgery, choosing less invasive treatment instead, new research suggests.Under certain conditions,women&n

Updated on: January 16,2024

Even with multiple breast tumors, mastectomy isn't always necessary: Study

by Denise MannSome women with multiple breast tumors can safely be spared breast removal surgery, choosing less invasive treatment instead, new research suggests.Under certain conditions,women&n

Updated on:January 16,2024

Inhibition of histone deacetylase 2 reduces MDM2 expression and reduces tumor growth in dedifferentiated liposarcoma

by OncotargetElevated HDAC2 mRNA expression is poorly prognostic in DDLPS. (A) mRNA expression of HDAC2 and disease-free survival (DFS) data from 52 subjects with DDLPS from The Cancer Genome Atlas (T

Updated on: May 11,2024

Inhibition of histone deacetylase 2 reduces MDM2 expression and reduces tumor growth in dedifferentiated liposarcoma

by OncotargetElevated HDAC2 mRNA expression is poorly prognostic in DDLPS. (A) mRNA expression of HDAC2 and disease-free survival (DFS) data from 52 subjects with DDLPS from The Cancer Genome Atlas (T

Updated on:May 11,2024

Young women often delay looking into breast symptoms, research finds

by Dennis ThompsonYoung women who find a lump or other potential signs of breast cancer often delay for weeks before finally seeing a doctor, a new study shows.On average, young women waited two weeks

Updated on: April 28,2024

Young women often delay looking into breast symptoms, research finds

by Dennis ThompsonYoung women who find a lump or other potential signs of breast cancer often delay for weeks before finally seeing a doctor, a new study shows.On average, young women waited two weeks

Updated on:April 28,2024

New treatment could be advance against cervical precancers

by Ernie MundellWomen who undergo regular Pap smears are no doubt familiar with the possibility of "precancerous" cells being detected.These cells—called cervical intraepithelial neoplasias

Updated on: April 28,2024

New treatment could be advance against cervical precancers

by Ernie MundellWomen who undergo regular Pap smears are no doubt familiar with the possibility of "precancerous" cells being detected.These cells—called cervical intraepithelial neoplasias

Updated on:April 28,2024