New review on p53 biology and reactivation in blood cancers

byKarolinska InstitutetA simplified scheme of p53 regulation in cells upon stress and the drugs currently evaluated in clinical trials for p53 reactivation for improved therapy in MDS and AML. C

Updated on: March 30,2024

New review on p53 biology and reactivation in blood cancers

byKarolinska InstitutetA simplified scheme of p53 regulation in cells upon stress and the drugs currently evaluated in clinical trials for p53 reactivation for improved therapy in MDS and AML. C

Updated on:March 30,2024

Deep proteomic profiling reveals possible therapeutic targets for medulloblastoma

byTranslational Genomics Research InstituteSample overview and subgroup classification. (A) Common molecular alterations and subgroup classifications of 20 MB PDX models. (B) Partial least squar

Updated on: January 04,2024

Deep proteomic profiling reveals possible therapeutic targets for medulloblastoma

byTranslational Genomics Research InstituteSample overview and subgroup classification. (A) Common molecular alterations and subgroup classifications of 20 MB PDX models. (B) Partial least squar

Updated on:January 04,2024

Policies favoring high-volume hospitals may disadvantage rural cancer patients

by University of PittsburghCredit: Pixabay/CC0 Public DomainPatients with cancer who live in rural Pennsylvania counties appear to know that they may have better outcomes if they receive their ca

Updated on: February 03,2024

Policies favoring high-volume hospitals may disadvantage rural cancer patients

by University of PittsburghCredit: Pixabay/CC0 Public DomainPatients with cancer who live in rural Pennsylvania counties appear to know that they may have better outcomes if they receive their ca

Updated on:February 03,2024

Some cancer immunotherapy treatments may damage fertility

by Monash UniversityCredit: Pixabay/CC0 Public DomainResearchers have discovered that some immunotherapy treatments used to treat cancer can cause fertility damage.It means these treatments could

Updated on: January 30,2024

Some cancer immunotherapy treatments may damage fertility

by Monash UniversityCredit: Pixabay/CC0 Public DomainResearchers have discovered that some immunotherapy treatments used to treat cancer can cause fertility damage.It means these treatments could

Updated on:January 30,2024

Leukemia, lymphoma squarely in sights of new class of drugs

by Will Sansom,University of Texas Health Science Center at San AntonioCredit: CC0 Public DomainUT Health San Antonio researchers, working with collaborators at the University of Florida, have d

Updated on: March 08,2024

Leukemia, lymphoma squarely in sights of new class of drugs

by Will Sansom,University of Texas Health Science Center at San AntonioCredit: CC0 Public DomainUT Health San Antonio researchers, working with collaborators at the University of Florida, have d

Updated on:March 08,2024

Public unaware of cancer risk from too little exercise, study reports

by Taylor & FrancisCredit: CC0 Public DomainIt has long been accepted that regular exercise can assist in helping to prevent or reduce the risk of a multitude of health problems. However, a n

Updated on: March 08,2024

Public unaware of cancer risk from too little exercise, study reports

by Taylor & FrancisCredit: CC0 Public DomainIt has long been accepted that regular exercise can assist in helping to prevent or reduce the risk of a multitude of health problems. However, a n

Updated on:March 08,2024

Some breast cancer patients are missing out on genetic counseling

by University of MichiganSteven Katz, M.D., MPH. Credit: Michigan MedicineAs new genes are linked to breast cancer occurring in families and as genetic testing becomes more important in directing

Updated on: May 21,2024

Some breast cancer patients are missing out on genetic counseling

by University of MichiganSteven Katz, M.D., MPH. Credit: Michigan MedicineAs new genes are linked to breast cancer occurring in families and as genetic testing becomes more important in directing

Updated on:May 21,2024

Skin cancer rewires its energy systems to spread more efficiently, finds study

by Queen Mary, University of LondonDifferent modes of migration and mitochondrial metabolism.a,bOxygen consumption rate (OCR) from cells embedded in a 3D collagen I matrix (n = 

Updated on: February 18,2024

Skin cancer rewires its energy systems to spread more efficiently, finds study

by Queen Mary, University of LondonDifferent modes of migration and mitochondrial metabolism.a,bOxygen consumption rate (OCR) from cells embedded in a 3D collagen I matrix (n = 

Updated on:February 18,2024

Researchers find genetic pathways to individualized treatment for advanced prostate cancer

by Mayo ClinicCredit: Mayo ClinicResearchers at Mayo Clinic Center for Individualized Medicine have uncovered genetic clues to why tumors resist a specific therapy used for treating advanced pros

Updated on: June 15,2024

Researchers find genetic pathways to individualized treatment for advanced prostate cancer

by Mayo ClinicCredit: Mayo ClinicResearchers at Mayo Clinic Center for Individualized Medicine have uncovered genetic clues to why tumors resist a specific therapy used for treating advanced pros

Updated on:June 15,2024

Researchers identify cell signaling pathways controlling melanoma cell metastasis to the brain

by H. Lee Moffitt Cancer Center & Research InstituteHDAC8 increases the establishment of melanoma brain metastases.a–cHDAC8 and EV expressing WM164 cells were introduced into NOD.

Updated on: June 22,2024

Researchers identify cell signaling pathways controlling melanoma cell metastasis to the brain

by H. Lee Moffitt Cancer Center & Research InstituteHDAC8 increases the establishment of melanoma brain metastases.a–cHDAC8 and EV expressing WM164 cells were introduced into NOD.

Updated on:June 22,2024

Peripheral surrogates of tumor burden to guide therapeutic strategies for HPV-associated malignancies

by Impact Journals LLCTumor intrinsic and extrinsic factors in the periphery that can serve as proxies of tumor burden. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28487A new review

Updated on: January 22,2024

Peripheral surrogates of tumor burden to guide therapeutic strategies for HPV-associated malignancies

by Impact Journals LLCTumor intrinsic and extrinsic factors in the periphery that can serve as proxies of tumor burden. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28487A new review

Updated on:January 22,2024

Preclinical study shows promise of systemic targeted therapy in a rare form of cancer

byVall d'Hebron Institute of OncologyTreatment with BRAF inhibitors reduces tumor cell proliferation in subcutaneous BRAFV600EPMP-PDX tumors without impacting in apoptosis. a–d) Mice b

Updated on: August 03,2024

Preclinical study shows promise of systemic targeted therapy in a rare form of cancer

byVall d'Hebron Institute of OncologyTreatment with BRAF inhibitors reduces tumor cell proliferation in subcutaneous BRAFV600EPMP-PDX tumors without impacting in apoptosis. a–d) Mice b

Updated on:August 03,2024