Deep proteomic profiling reveals possible therapeutic targets for medulloblastoma

byTranslational Genomics Research InstituteSample overview and subgroup classification. (A) Common molecular alterations and subgroup classifications of 20 MB PDX models. (B) Partial least squar

Updated on: January 04,2024

Deep proteomic profiling reveals possible therapeutic targets for medulloblastoma

byTranslational Genomics Research InstituteSample overview and subgroup classification. (A) Common molecular alterations and subgroup classifications of 20 MB PDX models. (B) Partial least squar

Updated on:January 04,2024

Link between sphingolipids and complement signaling may be key to stopping cancer metastasis

by Caroline Wallace,Medical University of South CarolinaGraphical Abstract. Credit:Cell Reports(2022). DOI: 10.1016/j.celrep.2022.111742MUSC Hollings Cancer Center researchers have i

Updated on: January 02,2024

Link between sphingolipids and complement signaling may be key to stopping cancer metastasis

by Caroline Wallace,Medical University of South CarolinaGraphical Abstract. Credit:Cell Reports(2022). DOI: 10.1016/j.celrep.2022.111742MUSC Hollings Cancer Center researchers have i

Updated on:January 02,2024

Vitamin D supplementation likely improves survival of cancers of the digestive tract, says researcher

by Boston University School of MedicineCredit: Unsplash/CC0 Public DomainFor more than 100 years, it has been believed that sunlight and vitamin D deficiency were associated with the risk for man

Updated on: January 30,2024

Vitamin D supplementation likely improves survival of cancers of the digestive tract, says researcher

by Boston University School of MedicineCredit: Unsplash/CC0 Public DomainFor more than 100 years, it has been believed that sunlight and vitamin D deficiency were associated with the risk for man

Updated on:January 30,2024

Promotion of cancer progression via extracellular vesicles

by Tokyo Medical and Dental UniversityUsually, blood vessels are stabilized, and their barrier function is maintained by the tight adhesion between vascular endothelial cells (①). When cancer cells me

Updated on: January 07,2024

Promotion of cancer progression via extracellular vesicles

by Tokyo Medical and Dental UniversityUsually, blood vessels are stabilized, and their barrier function is maintained by the tight adhesion between vascular endothelial cells (①). When cancer cells me

Updated on:January 07,2024

Research unveils genetic characteristics and improved prognosis of triple-negative apocrine carcinoma

by JooHyeon Heo,Ulsan National Institute of Science and TechnologySomatic Point Mutations in TNAC and LK-TNBC. The top 16 significantly mutated genes as determined by the dNdScv algorithm (p &lt

Updated on: February 18,2024

Research unveils genetic characteristics and improved prognosis of triple-negative apocrine carcinoma

by JooHyeon Heo,Ulsan National Institute of Science and TechnologySomatic Point Mutations in TNAC and LK-TNBC. The top 16 significantly mutated genes as determined by the dNdScv algorithm (p &lt

Updated on:February 18,2024

Research suggests a new approach for treatment-resistant breast cancers

by Louisiana State UniversityCB-103 shows synergy with paclitaxel and fulvestrant in breast cancer cell lines. TNBC (HCC1187) and ER+ BC (MCF-7) cells were treated with combinations of CB-103 (15

Updated on: February 18,2024

Research suggests a new approach for treatment-resistant breast cancers

by Louisiana State UniversityCB-103 shows synergy with paclitaxel and fulvestrant in breast cancer cell lines. TNBC (HCC1187) and ER+ BC (MCF-7) cells were treated with combinations of CB-103 (15

Updated on:February 18,2024

A novel method to better predict the outgrowth of ductal carcinoma in situ

by Netherlands Cancer InstituteGraphical abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.04.002An international team of researchers led by the Netherlands Cancer Institu

Updated on: February 03,2024

A novel method to better predict the outgrowth of ductal carcinoma in situ

by Netherlands Cancer InstituteGraphical abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.04.002An international team of researchers led by the Netherlands Cancer Institu

Updated on:February 03,2024

Skin cancer rewires its energy systems to spread more efficiently, finds study

by Queen Mary, University of LondonDifferent modes of migration and mitochondrial metabolism.a,bOxygen consumption rate (OCR) from cells embedded in a 3D collagen I matrix (n = 

Updated on: February 18,2024

Skin cancer rewires its energy systems to spread more efficiently, finds study

by Queen Mary, University of LondonDifferent modes of migration and mitochondrial metabolism.a,bOxygen consumption rate (OCR) from cells embedded in a 3D collagen I matrix (n = 

Updated on:February 18,2024

Enzyme inhibition promotes bone formation and curbs the development of bone metastases, study finds

byGerman Cancer Research CenterNegative regulation of bone formation by TAM receptor MERTK.amRNA expression analysis of TAM receptor familyMertk,Tyro3,Axl,Gas

Updated on: January 23,2024

Enzyme inhibition promotes bone formation and curbs the development of bone metastases, study finds

byGerman Cancer Research CenterNegative regulation of bone formation by TAM receptor MERTK.amRNA expression analysis of TAM receptor familyMertk,Tyro3,Axl,Gas

Updated on:January 23,2024

New test helps drug discoverers identify future cancer treatments

byInstitute of Cancer ResearchAn illustration of how the R2KD tool works Credit: Dr Maggie Liu, first authorResearchers have developed an investigative procedure that makes the early stages of d

Updated on: January 11,2024

New test helps drug discoverers identify future cancer treatments

byInstitute of Cancer ResearchAn illustration of how the R2KD tool works Credit: Dr Maggie Liu, first authorResearchers have developed an investigative procedure that makes the early stages of d

Updated on:January 11,2024

Microbial signature of colorectal cancer-associated mutations identified

by American Society for MicrobiologyCredit: CC0 Public DomainFor about 40% of people diagnosed with colorectal cancer (CRC), the tumor carries a mutation in a gene called KRAS. Many of those muta

Updated on: April 06,2024

Microbial signature of colorectal cancer-associated mutations identified

by American Society for MicrobiologyCredit: CC0 Public DomainFor about 40% of people diagnosed with colorectal cancer (CRC), the tumor carries a mutation in a gene called KRAS. Many of those muta

Updated on:April 06,2024

Placebo pill eases cancer-related fatigue in study

by Alan MozesPatients with advanced cancer often suffer crippling fatigue, but there has been little in the way of relief for them as they battle their disease.Now, a new investigation may have landed

Updated on: March 06,2024

Placebo pill eases cancer-related fatigue in study

by Alan MozesPatients with advanced cancer often suffer crippling fatigue, but there has been little in the way of relief for them as they battle their disease.Now, a new investigation may have landed

Updated on:March 06,2024