Bioengineered antibodies target mutant HER2 proteins

byNYU Langone HealthCredit: Unsplash/CC0 Public DomainFor some proteins, a single mutation, or change in its DNA instructions, is all it takes to tip the balance between functioning normally and

Updated on: November 10,2024

Bioengineered antibodies target mutant HER2 proteins

byNYU Langone HealthCredit: Unsplash/CC0 Public DomainFor some proteins, a single mutation, or change in its DNA instructions, is all it takes to tip the balance between functioning normally and

Updated on:November 10,2024

Genetic discovery paves the way for advanced pancreatic and colorectal cancer treatments

byUniversity of HelsinkiWild-type Kras deficient KPN cells show reduced metastatic capacity and increased immune infiltration. Credit:Nature Communications(2024). DOI: 10.1038/s41467

Updated on: November 10,2024

Genetic discovery paves the way for advanced pancreatic and colorectal cancer treatments

byUniversity of HelsinkiWild-type Kras deficient KPN cells show reduced metastatic capacity and increased immune infiltration. Credit:Nature Communications(2024). DOI: 10.1038/s41467

Updated on:November 10,2024

Discovery of new mechanism explains how ovarian cancer disables immune cells

byWeill Cornell Medical CollegeThis confocal micrograph shows two proteins,TAGLN2 (green) and FABP5 (red), are found together (yellow) on the surfaces of T cells, enabling the cells to pick up l

Updated on: November 11,2024

Discovery of new mechanism explains how ovarian cancer disables immune cells

byWeill Cornell Medical CollegeThis confocal micrograph shows two proteins,TAGLN2 (green) and FABP5 (red), are found together (yellow) on the surfaces of T cells, enabling the cells to pick up l

Updated on:November 11,2024

Researchers uncover new sarcoma gene

by Harry Perkins Institute of Medical ResearchCredit: CC0 Public DomainA team of WA researchers has uncovered new genes that could play an important role in the development of sarcoma, a group of

Updated on: June 15,2024

Researchers uncover new sarcoma gene

by Harry Perkins Institute of Medical ResearchCredit: CC0 Public DomainA team of WA researchers has uncovered new genes that could play an important role in the development of sarcoma, a group of

Updated on:June 15,2024

Inhibition of ribosome biogenesis as a novel approach for multi-stage cancer treatment

by Uppsala UniversityCredit: Uppsala UniversityNearly 90 percent of all cancer patient deaths are due to metastasis. A study from Uppsala University shows that a process that allows the cells to

Updated on: May 11,2024

Inhibition of ribosome biogenesis as a novel approach for multi-stage cancer treatment

by Uppsala UniversityCredit: Uppsala UniversityNearly 90 percent of all cancer patient deaths are due to metastasis. A study from Uppsala University shows that a process that allows the cells to

Updated on:May 11,2024

Researchers find prostate cancer drug byproduct can fuel cancer cells

by Cleveland ClinicNima Sharifi, MD, Cleveland Clinic Lerner Research Institute. Credit: Cleveland ClinicA genetic anomaly in certain men with prostate cancer may impact their response to common

Updated on: June 15,2024

Researchers find prostate cancer drug byproduct can fuel cancer cells

by Cleveland ClinicNima Sharifi, MD, Cleveland Clinic Lerner Research Institute. Credit: Cleveland ClinicA genetic anomaly in certain men with prostate cancer may impact their response to common

Updated on:June 15,2024

Study links mutations in notch gene to role in B cell cancers

by Perelman School of Medicine at the University of PennsylvaniaPeripheral blood with chronic lymphocytic leukemia cells. Credit: Jon Aster, Harvard Medical SchoolNotch is one of the most frequen

Updated on: July 02,2024

Study links mutations in notch gene to role in B cell cancers

by Perelman School of Medicine at the University of PennsylvaniaPeripheral blood with chronic lymphocytic leukemia cells. Credit: Jon Aster, Harvard Medical SchoolNotch is one of the most frequen

Updated on:July 02,2024

Technique targets cancer cells and leaves healthy ones alone

by Hebrew University of JerusalemTRPV2 protein in action. Credit: Hebrew University of JerusalemIt is a feeling that many who receive a cancer diagnosis can identify with: heartbreak and fear, fo

Updated on: April 18,2024

Technique targets cancer cells and leaves healthy ones alone

by Hebrew University of JerusalemTRPV2 protein in action. Credit: Hebrew University of JerusalemIt is a feeling that many who receive a cancer diagnosis can identify with: heartbreak and fear, fo

Updated on:April 18,2024

Synthetic molecule proves able to mitigate heart failure in translational study

by Maria Fernanda Ziegler,FAPESPThe vicious cycle of heart failure (HF). (i) Impaired aldehyde metabolism by aldehyde dehydrogenase 2 (ALDH2); (ii) accumulation of 4-hydroxynonenal (4-HNE), a re

Updated on: April 01,2024

Synthetic molecule proves able to mitigate heart failure in translational study

by Maria Fernanda Ziegler,FAPESPThe vicious cycle of heart failure (HF). (i) Impaired aldehyde metabolism by aldehyde dehydrogenase 2 (ALDH2); (ii) accumulation of 4-hydroxynonenal (4-HNE), a re

Updated on:April 01,2024

Mental health screenings urged for men with prostate cancer

byUniversity of South AustraliaCredit: Unsplash/CC0 Public DomainMental health screenings must be incorporated into routine prostate cancer diagnoses say University of South Australia researcher

Updated on: August 28,2024

Mental health screenings urged for men with prostate cancer

byUniversity of South AustraliaCredit: Unsplash/CC0 Public DomainMental health screenings must be incorporated into routine prostate cancer diagnoses say University of South Australia researcher

Updated on:August 28,2024

Depression linked to deadly inflammation in lung cancer patients

by Jeff Grabmeier,The Ohio State UniversityKaplan Meier survival curve for NSCLC patients stratified by NLR systemic inflammation, NLR < 5 and NLR ≥ 5 (n = 184), showing worse survival probab

Updated on: January 30,2024

Depression linked to deadly inflammation in lung cancer patients

by Jeff Grabmeier,The Ohio State UniversityKaplan Meier survival curve for NSCLC patients stratified by NLR systemic inflammation, NLR < 5 and NLR ≥ 5 (n = 184), showing worse survival probab

Updated on:January 30,2024

Molecular change to immunotherapy antibody could accelerate immune response to cancer

byWeizmann Institute of ScienceTissue sample of a particularly aggressive skin cancer reveals immune cells (yellow) that express on their surfaces a “brake pedal” receptor called FcgIIb (purple)

Updated on: January 02,2024

Molecular change to immunotherapy antibody could accelerate immune response to cancer

byWeizmann Institute of ScienceTissue sample of a particularly aggressive skin cancer reveals immune cells (yellow) that express on their surfaces a “brake pedal” receptor called FcgIIb (purple)

Updated on:January 02,2024