Deep proteomic profiling reveals possible therapeutic targets for medulloblastoma

byTranslational Genomics Research InstituteSample overview and subgroup classification. (A) Common molecular alterations and subgroup classifications of 20 MB PDX models. (B) Partial least squar

Updated on: January 04,2024

Deep proteomic profiling reveals possible therapeutic targets for medulloblastoma

byTranslational Genomics Research InstituteSample overview and subgroup classification. (A) Common molecular alterations and subgroup classifications of 20 MB PDX models. (B) Partial least squar

Updated on:January 04,2024

New research casts doubt on role of fungus in driving pancreatic cancer

byDuke University Medical CenterAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainFour years ago, a report that a common species of fungu

Updated on: January 12,2024

New research casts doubt on role of fungus in driving pancreatic cancer

byDuke University Medical CenterAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainFour years ago, a report that a common species of fungu

Updated on:January 12,2024

A novel method to better predict the outgrowth of ductal carcinoma in situ

by Netherlands Cancer InstituteGraphical abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.04.002An international team of researchers led by the Netherlands Cancer Institu

Updated on: February 03,2024

A novel method to better predict the outgrowth of ductal carcinoma in situ

by Netherlands Cancer InstituteGraphical abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.04.002An international team of researchers led by the Netherlands Cancer Institu

Updated on:February 03,2024

Skin cancer rewires its energy systems to spread more efficiently, finds study

by Queen Mary, University of LondonDifferent modes of migration and mitochondrial metabolism.a,bOxygen consumption rate (OCR) from cells embedded in a 3D collagen I matrix (n = 

Updated on: February 18,2024

Skin cancer rewires its energy systems to spread more efficiently, finds study

by Queen Mary, University of LondonDifferent modes of migration and mitochondrial metabolism.a,bOxygen consumption rate (OCR) from cells embedded in a 3D collagen I matrix (n = 

Updated on:February 18,2024

Specialized immune cells carry potential for new cancer immunotherapies

byLeiden UniversityTumor-infiltrating Vδ1 and Vδ3 T cell subsets display hallmarks of cytotoxic activity in MMR-d colon cancers. a, UMAP embedding showing the clustering of γδ T cells (n = 4,442

Updated on: January 23,2024

Specialized immune cells carry potential for new cancer immunotherapies

byLeiden UniversityTumor-infiltrating Vδ1 and Vδ3 T cell subsets display hallmarks of cytotoxic activity in MMR-d colon cancers. a, UMAP embedding showing the clustering of γδ T cells (n = 4,442

Updated on:January 23,2024

Immune targets for chemotherapy-resistant breast cancers identified

byKing's College LondonAnalysis of stromal TILs in residual disease and prognostic implications. A) Kaplan–Meier curves for i) progression free survival and ii) overall survival in ER+HER2-

Updated on: January 02,2024

Immune targets for chemotherapy-resistant breast cancers identified

byKing's College LondonAnalysis of stromal TILs in residual disease and prognostic implications. A) Kaplan–Meier curves for i) progression free survival and ii) overall survival in ER+HER2-

Updated on:January 02,2024

New study brings personalized immunotherapy prescriptions a step closer

byUniversity of BathCredit: Unsplash/CC0 Public DomainIn a step likely to advance personalized cancer treatment, scientists have—for the first time—shown in patients that levels of biomarkers ar

Updated on: January 13,2024

New study brings personalized immunotherapy prescriptions a step closer

byUniversity of BathCredit: Unsplash/CC0 Public DomainIn a step likely to advance personalized cancer treatment, scientists have—for the first time—shown in patients that levels of biomarkers ar

Updated on:January 13,2024

Shortage of vital children's cancer drug stirs fear and outrage

by Marie McCulloughCredit: CC0 Public DomainA critical shortage of a chemotherapy used to treat most childhood cancers has galvanized oncologists and parents of sick children.The U.S.medical com

Updated on: April 07,2024

Shortage of vital children's cancer drug stirs fear and outrage

by Marie McCulloughCredit: CC0 Public DomainA critical shortage of a chemotherapy used to treat most childhood cancers has galvanized oncologists and parents of sick children.The U.S.medical com

Updated on:April 07,2024

Many breast cancer survivors may be able to forgo mammograms in old age

by Denise MannOlder breast cancer survivors often have other medical issues and a shorter life expectancy than younger breast cancer survivors. What's more, their cancers are often slow-growing, a

Updated on: January 15,2024

Many breast cancer survivors may be able to forgo mammograms in old age

by Denise MannOlder breast cancer survivors often have other medical issues and a shorter life expectancy than younger breast cancer survivors. What's more, their cancers are often slow-growing, a

Updated on:January 15,2024

Study overturns dogma of cancer metabolism theory

by University of California, Los AngelesImage shows squamous cell skin cancer tumors with lactate production (a byproduct of glucose consumption) in purple. The tumor with lactate production bloc

Updated on: June 01,2024

Study overturns dogma of cancer metabolism theory

by University of California, Los AngelesImage shows squamous cell skin cancer tumors with lactate production (a byproduct of glucose consumption) in purple. The tumor with lactate production bloc

Updated on:June 01,2024

Immune response against skin-dwelling viruses prevents cancer

by Massachusetts General HospitalEarly skin cancer that is colonized with a commensal papillomavirus looks like a wart to the immune system and is effectively eliminated. Keratin 6+ hyperplastic

Updated on: April 14,2024

Immune response against skin-dwelling viruses prevents cancer

by Massachusetts General HospitalEarly skin cancer that is colonized with a commensal papillomavirus looks like a wart to the immune system and is effectively eliminated. Keratin 6+ hyperplastic

Updated on:April 14,2024

Study: ChemoID platform-predicted treatments lead to longer survival for glioblastoma patients

by Tim Tedeschi,University of CincinnatiGraphical Abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101025New multi-institutional phase 3 clinical trial data pub

Updated on: February 01,2024

Study: ChemoID platform-predicted treatments lead to longer survival for glioblastoma patients

by Tim Tedeschi,University of CincinnatiGraphical Abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101025New multi-institutional phase 3 clinical trial data pub

Updated on:February 01,2024