Investigators build a better targeted drug therapy using the power of computation

by Brigham and Women's HospitalCancer cell during cell division. Credit: National Institutes of HealthAntibody drug conjugates (ADCs)—cancer drugs that are designed to target and destroy canc

Updated on: June 08,2024

Investigators build a better targeted drug therapy using the power of computation

by Brigham and Women's HospitalCancer cell during cell division. Credit: National Institutes of HealthAntibody drug conjugates (ADCs)—cancer drugs that are designed to target and destroy canc

Updated on:June 08,2024

Researchers show potential liver cancer treatment by targeting cancer stem-like cells

by National University of SingaporeLiver cancer stem-like cells grown as tumourspheres that are sensitive to JAK/STAT small molecule inhibitors. Credit: National University of SingaporeLiver canc

Updated on: March 01,2024

Researchers show potential liver cancer treatment by targeting cancer stem-like cells

by National University of SingaporeLiver cancer stem-like cells grown as tumourspheres that are sensitive to JAK/STAT small molecule inhibitors. Credit: National University of SingaporeLiver canc

Updated on:March 01,2024

Depression linked to deadly inflammation in lung cancer patients

by Jeff Grabmeier,The Ohio State UniversityKaplan Meier survival curve for NSCLC patients stratified by NLR systemic inflammation, NLR < 5 and NLR ≥ 5 (n = 184), showing worse survival probab

Updated on: January 30,2024

Depression linked to deadly inflammation in lung cancer patients

by Jeff Grabmeier,The Ohio State UniversityKaplan Meier survival curve for NSCLC patients stratified by NLR systemic inflammation, NLR < 5 and NLR ≥ 5 (n = 184), showing worse survival probab

Updated on:January 30,2024

Study: Drugs reprogram genes in breast tumors to prevent endocrine resistance

by Sharita Forrest,University of Illinois at Urbana-ChampaignTargeting estrogen receptor-positive breast tumors with the XPO1 antagonist selinexor and the tamoxifen byproduct 4-OHT simultaneousl

Updated on: May 27,2024

Study: Drugs reprogram genes in breast tumors to prevent endocrine resistance

by Sharita Forrest,University of Illinois at Urbana-ChampaignTargeting estrogen receptor-positive breast tumors with the XPO1 antagonist selinexor and the tamoxifen byproduct 4-OHT simultaneousl

Updated on:May 27,2024

Can diet help cancer treatment? Study in mice offers clues

by Sara HusseinA study in the journalNaturefound that restricting the intake of an amino acid found in red meat and eggs slowed the growth of cancerous tumours in miceDiet is already a key

Updated on: May 11,2024

Can diet help cancer treatment? Study in mice offers clues

by Sara HusseinA study in the journalNaturefound that restricting the intake of an amino acid found in red meat and eggs slowed the growth of cancerous tumours in miceDiet is already a key

Updated on:May 11,2024

Researchers find new cancer gene drivers

by Bill Hathaway,Yale UniversityYale researchers exploring the structure of proteins have found evidence of how some genes drive the progression of cancer. Credit: Yale UniversityScientists have

Updated on: June 19,2024

Researchers find new cancer gene drivers

by Bill Hathaway,Yale UniversityYale researchers exploring the structure of proteins have found evidence of how some genes drive the progression of cancer. Credit: Yale UniversityScientists have

Updated on:June 19,2024

Survivorship standards help address the distinct needs of adult cancer survivors

byAmerican College of SurgeonsCredit: Thirdman from PexelsWith the number of adult cancer survivors in the United States expected to reach 23 million by 2032, the long-term needs of this populat

Updated on: July 05,2024

Survivorship standards help address the distinct needs of adult cancer survivors

byAmerican College of SurgeonsCredit: Thirdman from PexelsWith the number of adult cancer survivors in the United States expected to reach 23 million by 2032, the long-term needs of this populat

Updated on:July 05,2024

Study finds earlier mammograms for women with family history of breast cancer may not be needed

by Stephanie Winn,UC DavisCredit: Unsplash/CC0 Public DomainA new study released in the journalCancerreconsiders guidelines for when to start screening with mammograms if a woman has

Updated on: January 23,2024

Study finds earlier mammograms for women with family history of breast cancer may not be needed

by Stephanie Winn,UC DavisCredit: Unsplash/CC0 Public DomainA new study released in the journalCancerreconsiders guidelines for when to start screening with mammograms if a woman has

Updated on:January 23,2024

Inhibition of histone deacetylase 2 reduces MDM2 expression and reduces tumor growth in dedifferentiated liposarcoma

by OncotargetElevated HDAC2 mRNA expression is poorly prognostic in DDLPS. (A) mRNA expression of HDAC2 and disease-free survival (DFS) data from 52 subjects with DDLPS from The Cancer Genome Atlas (T

Updated on: May 11,2024

Inhibition of histone deacetylase 2 reduces MDM2 expression and reduces tumor growth in dedifferentiated liposarcoma

by OncotargetElevated HDAC2 mRNA expression is poorly prognostic in DDLPS. (A) mRNA expression of HDAC2 and disease-free survival (DFS) data from 52 subjects with DDLPS from The Cancer Genome Atlas (T

Updated on:May 11,2024

Researchers identify key metabolic regulators of drug resistance in the fight against pancreatic cancer

by Rebecca Brierley,University at BuffaloGraphical abstract. Credit:Molecular & Cellular Proteomics(2022). DOI: 10.1016/j.mcpro.2022.100409Researchers from the University at Buff

Updated on: February 20,2024

Researchers identify key metabolic regulators of drug resistance in the fight against pancreatic cancer

by Rebecca Brierley,University at BuffaloGraphical abstract. Credit:Molecular & Cellular Proteomics(2022). DOI: 10.1016/j.mcpro.2022.100409Researchers from the University at Buff

Updated on:February 20,2024

The sugar-attaching enzyme that defines colon cancer

by American Society for Biochemistry and Molecular BiologyThe enzyme GalNAc-T6 is selectively up-regulated in colon adenocarcinomas, and its expression is associated with a cancer-like growth pat

Updated on: April 14,2024

The sugar-attaching enzyme that defines colon cancer

by American Society for Biochemistry and Molecular BiologyThe enzyme GalNAc-T6 is selectively up-regulated in colon adenocarcinomas, and its expression is associated with a cancer-like growth pat

Updated on:April 14,2024

HPV immunization program cuts pre-cancer rates by more than half

by University of British ColumbiaGardasil vaccine and box. Image: WikipediaA school-based human papillomavirus (HPV) immunization program in British Columbia, Canada, is dramatically reducing rat

Updated on: March 01,2024

HPV immunization program cuts pre-cancer rates by more than half

by University of British ColumbiaGardasil vaccine and box. Image: WikipediaA school-based human papillomavirus (HPV) immunization program in British Columbia, Canada, is dramatically reducing rat

Updated on:March 01,2024