New promising targeted drug for a rare leukemia

by University of HelsinkiBCL-2 family gene expression in blasts across AML types at single cell resolution. (A) UMAP plot of scRNA-seq data of blasts from AML with megakaryoblastic differentiatio

Updated on: February 18,2024

New promising targeted drug for a rare leukemia

by University of HelsinkiBCL-2 family gene expression in blasts across AML types at single cell resolution. (A) UMAP plot of scRNA-seq data of blasts from AML with megakaryoblastic differentiatio

Updated on:February 18,2024

New review on p53 biology and reactivation in blood cancers

byKarolinska InstitutetA simplified scheme of p53 regulation in cells upon stress and the drugs currently evaluated in clinical trials for p53 reactivation for improved therapy in MDS and AML. C

Updated on: March 30,2024

New review on p53 biology and reactivation in blood cancers

byKarolinska InstitutetA simplified scheme of p53 regulation in cells upon stress and the drugs currently evaluated in clinical trials for p53 reactivation for improved therapy in MDS and AML. C

Updated on:March 30,2024

Researchers identify hallmarks to improving pancreatic cancer therapy

by University of California, IrvineInitiation and progression of pancreatic cancer. Pancreatic ductal adenocarcinoma (PDAC) forms from the exocrine tissue of the pancreas. Acinar and ductal cells

Updated on: February 01,2024

Researchers identify hallmarks to improving pancreatic cancer therapy

by University of California, IrvineInitiation and progression of pancreatic cancer. Pancreatic ductal adenocarcinoma (PDAC) forms from the exocrine tissue of the pancreas. Acinar and ductal cells

Updated on:February 01,2024

Why a promising breast cancer drug doesn't work—and how to improve it

by Katherine Fenz,Rockefeller UniversityER-mediated transcriptional resistance to BD inhibition. Credit:Nature Structural & Molecular Biology(2024). DOI: 10.1038/s41594-024-01384

Updated on: September 28,2024

Why a promising breast cancer drug doesn't work—and how to improve it

by Katherine Fenz,Rockefeller UniversityER-mediated transcriptional resistance to BD inhibition. Credit:Nature Structural & Molecular Biology(2024). DOI: 10.1038/s41594-024-01384

Updated on:September 28,2024

Genetic discovery paves the way for advanced pancreatic and colorectal cancer treatments

byUniversity of HelsinkiWild-type Kras deficient KPN cells show reduced metastatic capacity and increased immune infiltration. Credit:Nature Communications(2024). DOI: 10.1038/s41467

Updated on: November 10,2024

Genetic discovery paves the way for advanced pancreatic and colorectal cancer treatments

byUniversity of HelsinkiWild-type Kras deficient KPN cells show reduced metastatic capacity and increased immune infiltration. Credit:Nature Communications(2024). DOI: 10.1038/s41467

Updated on:November 10,2024

Young women often delay looking into breast symptoms, research finds

by Dennis ThompsonYoung women who find a lump or other potential signs of breast cancer often delay for weeks before finally seeing a doctor, a new study shows.On average, young women waited two weeks

Updated on: April 28,2024

Young women often delay looking into breast symptoms, research finds

by Dennis ThompsonYoung women who find a lump or other potential signs of breast cancer often delay for weeks before finally seeing a doctor, a new study shows.On average, young women waited two weeks

Updated on:April 28,2024

Study links mutations in notch gene to role in B cell cancers

by Perelman School of Medicine at the University of PennsylvaniaPeripheral blood with chronic lymphocytic leukemia cells. Credit: Jon Aster, Harvard Medical SchoolNotch is one of the most frequen

Updated on: July 02,2024

Study links mutations in notch gene to role in B cell cancers

by Perelman School of Medicine at the University of PennsylvaniaPeripheral blood with chronic lymphocytic leukemia cells. Credit: Jon Aster, Harvard Medical SchoolNotch is one of the most frequen

Updated on:July 02,2024

ASCO: Pembrolizumab superior for initial Tx of advanced NSCLC

(HealthDay)—For patients with programmed death ligand 1 (PD-L1)-expressing locally advanced or metastatic non-small-cell lung cancer (NSCLC), pembrolizumab is associated with better overall survival t

Updated on: March 30,2024

ASCO: Pembrolizumab superior for initial Tx of advanced NSCLC

(HealthDay)—For patients with programmed death ligand 1 (PD-L1)-expressing locally advanced or metastatic non-small-cell lung cancer (NSCLC), pembrolizumab is associated with better overall survival t

Updated on:March 30,2024

Ancient viruses could help kill cancers

by The Francis Crick InstituteHeatmap showing expression of melanoma-specific transcripts across a range of cancer types. The three columns with high expression are from melanoma samples. Credit:

Updated on: March 30,2024

Ancient viruses could help kill cancers

by The Francis Crick InstituteHeatmap showing expression of melanoma-specific transcripts across a range of cancer types. The three columns with high expression are from melanoma samples. Credit:

Updated on:March 30,2024

Technique targets cancer cells and leaves healthy ones alone

by Hebrew University of JerusalemTRPV2 protein in action. Credit: Hebrew University of JerusalemIt is a feeling that many who receive a cancer diagnosis can identify with: heartbreak and fear, fo

Updated on: April 18,2024

Technique targets cancer cells and leaves healthy ones alone

by Hebrew University of JerusalemTRPV2 protein in action. Credit: Hebrew University of JerusalemIt is a feeling that many who receive a cancer diagnosis can identify with: heartbreak and fear, fo

Updated on:April 18,2024

Scientist identifies gene responsible for spread of prostate cancer

by Caitlin Coyle,Rutgers UniversityAntonina Mitrofanova is a pioneer in the emerging field of biomedical informatics, fighting cancer with big data. Credit: Nick RomanenkoA Rutgers study has fou

Updated on: March 06,2024

Scientist identifies gene responsible for spread of prostate cancer

by Caitlin Coyle,Rutgers UniversityAntonina Mitrofanova is a pioneer in the emerging field of biomedical informatics, fighting cancer with big data. Credit: Nick RomanenkoA Rutgers study has fou

Updated on:March 06,2024

Protein could offer therapeutic target for pancreatic cancer

by The Francis Crick InstituteHuman pancreatic ductal adenocarcinoma showing high levels of CD9 (red). Credit: Francis Crick InstituteA protein that drives growth of pancreatic cancer, and which

Updated on: March 01,2024

Protein could offer therapeutic target for pancreatic cancer

by The Francis Crick InstituteHuman pancreatic ductal adenocarcinoma showing high levels of CD9 (red). Credit: Francis Crick InstituteA protein that drives growth of pancreatic cancer, and which

Updated on:March 01,2024