Researchers identify potential biomarker to distinguish two aggressive types of brain tumors in children

by Johns Hopkins University School of MedicineSMYD3 overexpression activates the EGFR pathway in CHLA01 cells. (A) Localization of endogenous SMYD3. Representative 60x Z-stack confocal images sho

Updated on: January 30,2024

Researchers identify potential biomarker to distinguish two aggressive types of brain tumors in children

by Johns Hopkins University School of MedicineSMYD3 overexpression activates the EGFR pathway in CHLA01 cells. (A) Localization of endogenous SMYD3. Representative 60x Z-stack confocal images sho

Updated on:January 30,2024

Potential melanoma target bypasses therapeutic resistance to immune checkpoint blockers

by Jeff Hansen,University of Alabama at BirminghamConstitutive activation of JAK1/2 in IFNγR1KOmelanoma cells. a Identification of a JAK1/2-centric network of activated protein tyrosine ki

Updated on: January 02,2024

Potential melanoma target bypasses therapeutic resistance to immune checkpoint blockers

by Jeff Hansen,University of Alabama at BirminghamConstitutive activation of JAK1/2 in IFNγR1KOmelanoma cells. a Identification of a JAK1/2-centric network of activated protein tyrosine ki

Updated on:January 02,2024

Investigators reveal changes to immune status in patient tumors after radiation

by Roswell Park Comprehensive Cancer CenterCredit: Pixabay/CC0 Public DomainLittle is known about how radiation therapy to kill cancer cells affects immune cells and other components of patient tumors

Updated on: January 30,2024

Investigators reveal changes to immune status in patient tumors after radiation

by Roswell Park Comprehensive Cancer CenterCredit: Pixabay/CC0 Public DomainLittle is known about how radiation therapy to kill cancer cells affects immune cells and other components of patient tumors

Updated on:January 30,2024

New research casts doubt on role of fungus in driving pancreatic cancer

byDuke University Medical CenterAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainFour years ago, a report that a common species of fungu

Updated on: January 12,2024

New research casts doubt on role of fungus in driving pancreatic cancer

byDuke University Medical CenterAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainFour years ago, a report that a common species of fungu

Updated on:January 12,2024

Biological pathways provide evidence for how to overcome barriers limiting cancer immunotherapies

byUNC Lineberger Comprehensive Cancer CenterCredit: Unsplash/CC0 Public DomainResearchers at UNC Lineberger Comprehensive Cancer Center have found a possible way to overcome barriers that block

Updated on: January 04,2024

Biological pathways provide evidence for how to overcome barriers limiting cancer immunotherapies

byUNC Lineberger Comprehensive Cancer CenterCredit: Unsplash/CC0 Public DomainResearchers at UNC Lineberger Comprehensive Cancer Center have found a possible way to overcome barriers that block

Updated on:January 04,2024

Researchers develop novel approach for predicting resistance against cancer therapy

by National University of SingaporeMultispectral microscopy with quantitative immunofluorescence is a state-of-the-art technology that can detect oncogenes simultaneously, allowing for the identi

Updated on: February 18,2024

Researchers develop novel approach for predicting resistance against cancer therapy

by National University of SingaporeMultispectral microscopy with quantitative immunofluorescence is a state-of-the-art technology that can detect oncogenes simultaneously, allowing for the identi

Updated on:February 18,2024

Study reports blocking key enzyme boosts anti-cancer T-cell responses and resistance to immunosuppression

byLouisiana State UniversityCredit:Frontiers in ImmunologyDOI: 10.3389/fimmu.2022.987298A study led by LSU Health New Orleans cancer researchers describes a novel therapeutic strateg

Updated on: January 16,2024

Study reports blocking key enzyme boosts anti-cancer T-cell responses and resistance to immunosuppression

byLouisiana State UniversityCredit:Frontiers in ImmunologyDOI: 10.3389/fimmu.2022.987298A study led by LSU Health New Orleans cancer researchers describes a novel therapeutic strateg

Updated on:January 16,2024

New study brings personalized immunotherapy prescriptions a step closer

byUniversity of BathCredit: Unsplash/CC0 Public DomainIn a step likely to advance personalized cancer treatment, scientists have—for the first time—shown in patients that levels of biomarkers ar

Updated on: January 13,2024

New study brings personalized immunotherapy prescriptions a step closer

byUniversity of BathCredit: Unsplash/CC0 Public DomainIn a step likely to advance personalized cancer treatment, scientists have—for the first time—shown in patients that levels of biomarkers ar

Updated on:January 13,2024

Researchers identify novel gene networks associated with aggressive type of breast cancer

by Savannah Williamson,Georgia Institute of TechnologyGene enrichment for select Basal-like network modules. Network diagram for eight nonconserved Basal-like modules that include OS genes. Node

Updated on: April 28,2024

Researchers identify novel gene networks associated with aggressive type of breast cancer

by Savannah Williamson,Georgia Institute of TechnologyGene enrichment for select Basal-like network modules. Network diagram for eight nonconserved Basal-like modules that include OS genes. Node

Updated on:April 28,2024

Study could explain link between high-cholesterol diet and colon cancer

by University of California, Los AngelesA pale-blue stain shows stem cells multiplying in a mouse's intestine. Credit: Tontonoz lab/UCLANew UCLA research could help explain the link between a

Updated on: June 28,2024

Study could explain link between high-cholesterol diet and colon cancer

by University of California, Los AngelesA pale-blue stain shows stem cells multiplying in a mouse's intestine. Credit: Tontonoz lab/UCLANew UCLA research could help explain the link between a

Updated on:June 28,2024

Immune system B-cells can help predict HER2-positive breast cancer treatment response

byUNC Lineberger Comprehensive Cancer CenterThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: NCI Ce

Updated on: January 02,2024

Immune system B-cells can help predict HER2-positive breast cancer treatment response

byUNC Lineberger Comprehensive Cancer CenterThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: NCI Ce

Updated on:January 02,2024

An unexpected journey reveals a potent way to attack tumors

by Nancy Fliesler,Children's Hospital BostonSenescence inducer CuSO4, which causes ER stress, activates NKp46- and NKG2D-dependent NK killing, but 4-PBA, which induces senescence without ER

Updated on: February 23,2024

An unexpected journey reveals a potent way to attack tumors

by Nancy Fliesler,Children's Hospital BostonSenescence inducer CuSO4, which causes ER stress, activates NKp46- and NKG2D-dependent NK killing, but 4-PBA, which induces senescence without ER

Updated on:February 23,2024