T-cell interactions vary between tumor microenvironments

by Melissa Rohman,Northwestern UniversityShown is a p-STAT3- non-reactive astrocyte (white arrow) in close proximity to a CD3+p-STAT3- T cell (blue arrow) and a CD163+p-STAT3- macrophage (red ar

Updated on: April 01,2024

T-cell interactions vary between tumor microenvironments

by Melissa Rohman,Northwestern UniversityShown is a p-STAT3- non-reactive astrocyte (white arrow) in close proximity to a CD3+p-STAT3- T cell (blue arrow) and a CD163+p-STAT3- macrophage (red ar

Updated on:April 01,2024

Killing pancreatic cancer with T cells that supercharge themselves

by University of California, San FranciscoTherapeutic T cells engineered with tumor-triggered IL-2 production infiltrate and clear immune-excluded tumors. (A) We hypothesized that cell autonomous

Updated on: February 18,2024

Killing pancreatic cancer with T cells that supercharge themselves

by University of California, San FranciscoTherapeutic T cells engineered with tumor-triggered IL-2 production infiltrate and clear immune-excluded tumors. (A) We hypothesized that cell autonomous

Updated on:February 18,2024

Maternal obesity may promote liver cancer

by University of GenevaCredit:JHEP Reports(2024). DOI: 10.1016/j.jhepr.2024.101056Obesity, which could reach 50% of the population in certain developed countries by 2030, is a major p

Updated on: March 20,2024

Maternal obesity may promote liver cancer

by University of GenevaCredit:JHEP Reports(2024). DOI: 10.1016/j.jhepr.2024.101056Obesity, which could reach 50% of the population in certain developed countries by 2030, is a major p

Updated on:March 20,2024

Hypnosis may help reduce distress of cancer treatment in children

by University of ExeterHypnosis may help reduce the distress of cancer treatment in children. Credit: University of ExeterHypnosis could help to reduce the fear of medical procedures in children

Updated on: March 01,2024

Hypnosis may help reduce distress of cancer treatment in children

by University of ExeterHypnosis may help reduce the distress of cancer treatment in children. Credit: University of ExeterHypnosis could help to reduce the fear of medical procedures in children

Updated on:March 01,2024

A machine learning-based algorithm to predict which cancer patients benefit from immunotherapy

by Institute for Research in Biomedicine (IRB Barcelona)Credit: CC0 Public DomainScientists at the Institute for Research in Biomedicine (IRB Barcelona), in collaboration with the Centre for Geno

Updated on: May 20,2024

A machine learning-based algorithm to predict which cancer patients benefit from immunotherapy

by Institute for Research in Biomedicine (IRB Barcelona)Credit: CC0 Public DomainScientists at the Institute for Research in Biomedicine (IRB Barcelona), in collaboration with the Centre for Geno

Updated on:May 20,2024

Study could explain link between high-cholesterol diet and colon cancer

by University of California, Los AngelesA pale-blue stain shows stem cells multiplying in a mouse's intestine. Credit: Tontonoz lab/UCLANew UCLA research could help explain the link between a

Updated on: June 28,2024

Study could explain link between high-cholesterol diet and colon cancer

by University of California, Los AngelesA pale-blue stain shows stem cells multiplying in a mouse's intestine. Credit: Tontonoz lab/UCLANew UCLA research could help explain the link between a

Updated on:June 28,2024

Researchers identify novel oncogenic function for receptor linked to Alzheimer's disease

by University of TurkuCredit: CC0 Public DomainCommon and rare SORLA single nucleotide polymorphisms have been associated with the development of Alzheimer's disease. So far, SORLA has been m

Updated on: March 12,2024

Researchers identify novel oncogenic function for receptor linked to Alzheimer's disease

by University of TurkuCredit: CC0 Public DomainCommon and rare SORLA single nucleotide polymorphisms have been associated with the development of Alzheimer's disease. So far, SORLA has been m

Updated on:March 12,2024

Novel bioassay predicts cancer patients' response to immunotherapy

byBen-Gurion University of the NegevIcAR response to fresh and fixed PDXs and generation of an IcAR score.(A) Schematic representation of the IcAR assay protocol. Following flow cytometry determ

Updated on: January 12,2024

Novel bioassay predicts cancer patients' response to immunotherapy

byBen-Gurion University of the NegevIcAR response to fresh and fixed PDXs and generation of an IcAR score.(A) Schematic representation of the IcAR assay protocol. Following flow cytometry determ

Updated on:January 12,2024

Carcinogens found at Montana nuclear missile sites as reports of hundreds of cancers surface

by Tara CoppIn this image provided by the U.S. Air Force, Airman 1st Class Jackson Ligon, left, and Senior Airman Jonathan Marinaccio, 341st Missile Maintenance Squadron technicians connect a re-entry

Updated on: February 18,2024

Carcinogens found at Montana nuclear missile sites as reports of hundreds of cancers surface

by Tara CoppIn this image provided by the U.S. Air Force, Airman 1st Class Jackson Ligon, left, and Senior Airman Jonathan Marinaccio, 341st Missile Maintenance Squadron technicians connect a re-entry

Updated on:February 18,2024

Skin cancer rewires its energy systems to spread more efficiently, finds study

by Queen Mary, University of LondonDifferent modes of migration and mitochondrial metabolism.a,bOxygen consumption rate (OCR) from cells embedded in a 3D collagen I matrix (n = 

Updated on: February 18,2024

Skin cancer rewires its energy systems to spread more efficiently, finds study

by Queen Mary, University of LondonDifferent modes of migration and mitochondrial metabolism.a,bOxygen consumption rate (OCR) from cells embedded in a 3D collagen I matrix (n = 

Updated on:February 18,2024

New technique adds to the expanding suite of TAPS capabilities

byLudwig Cancer ResearchDevelopment of wglrTAPS. (A) Schematic representation of the wglrTAPS. (B) Sequence length distribution of wglrTAPS HiFi read. (C) Conversion rate of wglrTAPS at methylat

Updated on: January 13,2024

New technique adds to the expanding suite of TAPS capabilities

byLudwig Cancer ResearchDevelopment of wglrTAPS. (A) Schematic representation of the wglrTAPS. (B) Sequence length distribution of wglrTAPS HiFi read. (C) Conversion rate of wglrTAPS at methylat

Updated on:January 13,2024

Elegant antibody nanoparticles override immunological tolerance of tumors

by Chinese Academy of SciencesSchematic illustration of the engineered antibody nanoparticle for robust cancer immunotherapy. Credit: WANG DanggeImmune checkpoint blockade (ICB) therapy using the

Updated on: May 09,2024

Elegant antibody nanoparticles override immunological tolerance of tumors

by Chinese Academy of SciencesSchematic illustration of the engineered antibody nanoparticle for robust cancer immunotherapy. Credit: WANG DanggeImmune checkpoint blockade (ICB) therapy using the

Updated on:May 09,2024