Study uncovers epigenetic source of resistance to targeted therapy in EGFR-mutant lung cancer

by Dana-Farber Cancer InstituteCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.07.005When lung cancers driven by mutations in the EGFR gene become resistant to osimertinib or othe

Updated on: February 01,2024

Study uncovers epigenetic source of resistance to targeted therapy in EGFR-mutant lung cancer

by Dana-Farber Cancer InstituteCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.07.005When lung cancers driven by mutations in the EGFR gene become resistant to osimertinib or othe

Updated on:February 01,2024

A new tumor-suppressive gene that boosts personalized treatment response in breast cancer

by The University of Hong KongGraphical Abstract. Credit:Cell Reports(2022). DOI: 10.1016/j.celrep.2022.111821A research team from LKS Faculty of Medicine, the University of Hong Kong

Updated on: January 30,2024

A new tumor-suppressive gene that boosts personalized treatment response in breast cancer

by The University of Hong KongGraphical Abstract. Credit:Cell Reports(2022). DOI: 10.1016/j.celrep.2022.111821A research team from LKS Faculty of Medicine, the University of Hong Kong

Updated on:January 30,2024

T-cell interactions vary between tumor microenvironments

by Melissa Rohman,Northwestern UniversityShown is a p-STAT3- non-reactive astrocyte (white arrow) in close proximity to a CD3+p-STAT3- T cell (blue arrow) and a CD163+p-STAT3- macrophage (red ar

Updated on: April 01,2024

T-cell interactions vary between tumor microenvironments

by Melissa Rohman,Northwestern UniversityShown is a p-STAT3- non-reactive astrocyte (white arrow) in close proximity to a CD3+p-STAT3- T cell (blue arrow) and a CD163+p-STAT3- macrophage (red ar

Updated on:April 01,2024

Periostin shows promise to help fight a common form of esophageal cancer

byElsevierSchematic diagram of roles of periostin (POSTN) in the esophageal squamous cell carcinoma (ESCC) microenvironment. Direct contact with ESCC cells leads mesenchymal stem cells (MSCs) to

Updated on: April 28,2024

Periostin shows promise to help fight a common form of esophageal cancer

byElsevierSchematic diagram of roles of periostin (POSTN) in the esophageal squamous cell carcinoma (ESCC) microenvironment. Direct contact with ESCC cells leads mesenchymal stem cells (MSCs) to

Updated on:April 28,2024

A machine learning-based algorithm to predict which cancer patients benefit from immunotherapy

by Institute for Research in Biomedicine (IRB Barcelona)Credit: CC0 Public DomainScientists at the Institute for Research in Biomedicine (IRB Barcelona), in collaboration with the Centre for Geno

Updated on: May 20,2024

A machine learning-based algorithm to predict which cancer patients benefit from immunotherapy

by Institute for Research in Biomedicine (IRB Barcelona)Credit: CC0 Public DomainScientists at the Institute for Research in Biomedicine (IRB Barcelona), in collaboration with the Centre for Geno

Updated on:May 20,2024

A step toward understanding gastric cancer

by Sanjay Mishra,Vanderbilt UniversityHistopathology of Helicobacter pylori infection in a gastric foveolar pit demonstrated in endoscopic gastric biopsy. Credit: Wikipedia.Helicobacter pylori&n

Updated on: April 18,2024

A step toward understanding gastric cancer

by Sanjay Mishra,Vanderbilt UniversityHistopathology of Helicobacter pylori infection in a gastric foveolar pit demonstrated in endoscopic gastric biopsy. Credit: Wikipedia.Helicobacter pylori&n

Updated on:April 18,2024

Study could explain link between high-cholesterol diet and colon cancer

by University of California, Los AngelesA pale-blue stain shows stem cells multiplying in a mouse's intestine. Credit: Tontonoz lab/UCLANew UCLA research could help explain the link between a

Updated on: June 28,2024

Study could explain link between high-cholesterol diet and colon cancer

by University of California, Los AngelesA pale-blue stain shows stem cells multiplying in a mouse's intestine. Credit: Tontonoz lab/UCLANew UCLA research could help explain the link between a

Updated on:June 28,2024

Scientist identifies gene responsible for spread of prostate cancer

by Caitlin Coyle,Rutgers UniversityAntonina Mitrofanova is a pioneer in the emerging field of biomedical informatics, fighting cancer with big data. Credit: Nick RomanenkoA Rutgers study has fou

Updated on: March 06,2024

Scientist identifies gene responsible for spread of prostate cancer

by Caitlin Coyle,Rutgers UniversityAntonina Mitrofanova is a pioneer in the emerging field of biomedical informatics, fighting cancer with big data. Credit: Nick RomanenkoA Rutgers study has fou

Updated on:March 06,2024

Study: Drugs reprogram genes in breast tumors to prevent endocrine resistance

by Sharita Forrest,University of Illinois at Urbana-ChampaignTargeting estrogen receptor-positive breast tumors with the XPO1 antagonist selinexor and the tamoxifen byproduct 4-OHT simultaneousl

Updated on: May 27,2024

Study: Drugs reprogram genes in breast tumors to prevent endocrine resistance

by Sharita Forrest,University of Illinois at Urbana-ChampaignTargeting estrogen receptor-positive breast tumors with the XPO1 antagonist selinexor and the tamoxifen byproduct 4-OHT simultaneousl

Updated on:May 27,2024

Overweight before age 40 increases cancer risk

by Kim E. Andreassen,University of BergenObesity is a risk factor for many types of cancer. Credit: Colourbox.In an international study, lead by the University of Bergen, the researchers wanted

Updated on: March 14,2024

Overweight before age 40 increases cancer risk

by Kim E. Andreassen,University of BergenObesity is a risk factor for many types of cancer. Credit: Colourbox.In an international study, lead by the University of Bergen, the researchers wanted

Updated on:March 14,2024

'Fighting' cancer may detract men from palliative care

by University of Rochester Medical CenterMen with advanced cancer are 30 percent less likely than women to consider palliative care, according to a University of Rochester Medical Center study.Re

Updated on: March 01,2024

'Fighting' cancer may detract men from palliative care

by University of Rochester Medical CenterMen with advanced cancer are 30 percent less likely than women to consider palliative care, according to a University of Rochester Medical Center study.Re

Updated on:March 01,2024

Researchers unveil the origin of second pediatric cancers and chemotherapy-induced mutations in healthy tissues

byInstitute for Research in Biomedicine (IRB Barcelona)The origin of second solid tumors of cases 3 (A–D) and 4 (E–F). A, Eight years after the development of NB, the child presented with MRT. B

Updated on: March 30,2024

Researchers unveil the origin of second pediatric cancers and chemotherapy-induced mutations in healthy tissues

byInstitute for Research in Biomedicine (IRB Barcelona)The origin of second solid tumors of cases 3 (A–D) and 4 (E–F). A, Eight years after the development of NB, the child presented with MRT. B

Updated on:March 30,2024