Enhanced anticancer compound may allow precise activation and tracking of treatment

by The Wistar InstituteCredit: The Wistar InstituteResearchers at The Wistar Institute and the University of South Florida have advanced a novel compound that specifically targets the endoplasmic

Updated on: April 18,2024

Enhanced anticancer compound may allow precise activation and tracking of treatment

by The Wistar InstituteCredit: The Wistar InstituteResearchers at The Wistar Institute and the University of South Florida have advanced a novel compound that specifically targets the endoplasmic

Updated on:April 18,2024

Microbiome predicts blood infections in pediatric cancer patients

by CU Anschutz Medical CampusBryan Nycz, 3rd-year medical student at the University of Colorado School of Medicine, and scientific mentors show association between microbiome and blood infections

Updated on: March 01,2024

Microbiome predicts blood infections in pediatric cancer patients

by CU Anschutz Medical CampusBryan Nycz, 3rd-year medical student at the University of Colorado School of Medicine, and scientific mentors show association between microbiome and blood infections

Updated on:March 01,2024

Researchers identify novel oncogenic function for receptor linked to Alzheimer's disease

by University of TurkuCredit: CC0 Public DomainCommon and rare SORLA single nucleotide polymorphisms have been associated with the development of Alzheimer's disease. So far, SORLA has been m

Updated on: March 12,2024

Researchers identify novel oncogenic function for receptor linked to Alzheimer's disease

by University of TurkuCredit: CC0 Public DomainCommon and rare SORLA single nucleotide polymorphisms have been associated with the development of Alzheimer's disease. So far, SORLA has been m

Updated on:March 12,2024

Novel bioassay predicts cancer patients' response to immunotherapy

byBen-Gurion University of the NegevIcAR response to fresh and fixed PDXs and generation of an IcAR score.(A) Schematic representation of the IcAR assay protocol. Following flow cytometry determ

Updated on: January 12,2024

Novel bioassay predicts cancer patients' response to immunotherapy

byBen-Gurion University of the NegevIcAR response to fresh and fixed PDXs and generation of an IcAR score.(A) Schematic representation of the IcAR assay protocol. Following flow cytometry determ

Updated on:January 12,2024

Study uncovers epigenetic source of resistance to targeted therapy in EGFR-mutant lung cancer

by Dana-Farber Cancer InstituteCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.07.005When lung cancers driven by mutations in the EGFR gene become resistant to osimertinib or othe

Updated on: February 01,2024

Study uncovers epigenetic source of resistance to targeted therapy in EGFR-mutant lung cancer

by Dana-Farber Cancer InstituteCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.07.005When lung cancers driven by mutations in the EGFR gene become resistant to osimertinib or othe

Updated on:February 01,2024

Carcinogens found at Montana nuclear missile sites as reports of hundreds of cancers surface

by Tara CoppIn this image provided by the U.S. Air Force, Airman 1st Class Jackson Ligon, left, and Senior Airman Jonathan Marinaccio, 341st Missile Maintenance Squadron technicians connect a re-entry

Updated on: February 18,2024

Carcinogens found at Montana nuclear missile sites as reports of hundreds of cancers surface

by Tara CoppIn this image provided by the U.S. Air Force, Airman 1st Class Jackson Ligon, left, and Senior Airman Jonathan Marinaccio, 341st Missile Maintenance Squadron technicians connect a re-entry

Updated on:February 18,2024

Skin cancer rewires its energy systems to spread more efficiently, finds study

by Queen Mary, University of LondonDifferent modes of migration and mitochondrial metabolism.a,bOxygen consumption rate (OCR) from cells embedded in a 3D collagen I matrix (n = 

Updated on: February 18,2024

Skin cancer rewires its energy systems to spread more efficiently, finds study

by Queen Mary, University of LondonDifferent modes of migration and mitochondrial metabolism.a,bOxygen consumption rate (OCR) from cells embedded in a 3D collagen I matrix (n = 

Updated on:February 18,2024

Elegant antibody nanoparticles override immunological tolerance of tumors

by Chinese Academy of SciencesSchematic illustration of the engineered antibody nanoparticle for robust cancer immunotherapy. Credit: WANG DanggeImmune checkpoint blockade (ICB) therapy using the

Updated on: May 09,2024

Elegant antibody nanoparticles override immunological tolerance of tumors

by Chinese Academy of SciencesSchematic illustration of the engineered antibody nanoparticle for robust cancer immunotherapy. Credit: WANG DanggeImmune checkpoint blockade (ICB) therapy using the

Updated on:May 09,2024

With vibrator used in cell phones, researchers develop 3D tumor spheroids to screen for anti-cancer drugs

by Brigham and Women’s HospitalCredit:Device(2024). DOI: 10.1016/j.device.2024.100255Depending on their location, cancer cells within a three-dimensional (3D) tumor structure can have

Updated on: March 05,2024

With vibrator used in cell phones, researchers develop 3D tumor spheroids to screen for anti-cancer drugs

by Brigham and Women’s HospitalCredit:Device(2024). DOI: 10.1016/j.device.2024.100255Depending on their location, cancer cells within a three-dimensional (3D) tumor structure can have

Updated on:March 05,2024

Reconsidering oxygen's role in growth of tumors

byYale UniversityGraphical abstract. Credit:Cell Systems(2022). DOI: 10.1016/j.cels.2022.11.003Yale researchers have made a discovery that changes conventional thinking about the rol

Updated on: January 22,2024

Reconsidering oxygen's role in growth of tumors

byYale UniversityGraphical abstract. Credit:Cell Systems(2022). DOI: 10.1016/j.cels.2022.11.003Yale researchers have made a discovery that changes conventional thinking about the rol

Updated on:January 22,2024

Killing pancreatic cancer with T cells that supercharge themselves

by University of California, San FranciscoTherapeutic T cells engineered with tumor-triggered IL-2 production infiltrate and clear immune-excluded tumors. (A) We hypothesized that cell autonomous

Updated on: February 18,2024

Killing pancreatic cancer with T cells that supercharge themselves

by University of California, San FranciscoTherapeutic T cells engineered with tumor-triggered IL-2 production infiltrate and clear immune-excluded tumors. (A) We hypothesized that cell autonomous

Updated on:February 18,2024

Regorafenib shown to augment antitumor effect of anti-PD-1 immunotherapy in advanced gastric cancers

byKumamoto UniversityCredit:Cancer Research(2022). DOI: 10.1158/0008-5472.CAN-22-1890Fibrotic cancers such as gastric cancers are highly resistant to conventional therapies like immu

Updated on: January 03,2024

Regorafenib shown to augment antitumor effect of anti-PD-1 immunotherapy in advanced gastric cancers

byKumamoto UniversityCredit:Cancer Research(2022). DOI: 10.1158/0008-5472.CAN-22-1890Fibrotic cancers such as gastric cancers are highly resistant to conventional therapies like immu

Updated on:January 03,2024