Potential therapeutic target for small cell lung cancer discovered

by Melissa Rohman,Northwestern UniversityGraphic model showing how POU2AF2 establishes the poised enhancer via SWI/SNF activity-dependent recruitment of the Polycomb complex in SCLC-P subtype ce

Updated on: April 28,2024

Potential therapeutic target for small cell lung cancer discovered

by Melissa Rohman,Northwestern UniversityGraphic model showing how POU2AF2 establishes the poised enhancer via SWI/SNF activity-dependent recruitment of the Polycomb complex in SCLC-P subtype ce

Updated on:April 28,2024

ASCO: Pembrolizumab superior for initial Tx of advanced NSCLC

(HealthDay)—For patients with programmed death ligand 1 (PD-L1)-expressing locally advanced or metastatic non-small-cell lung cancer (NSCLC), pembrolizumab is associated with better overall survival t

Updated on: March 30,2024

ASCO: Pembrolizumab superior for initial Tx of advanced NSCLC

(HealthDay)—For patients with programmed death ligand 1 (PD-L1)-expressing locally advanced or metastatic non-small-cell lung cancer (NSCLC), pembrolizumab is associated with better overall survival t

Updated on:March 30,2024

Synthetic molecule proves able to mitigate heart failure in translational study

by Maria Fernanda Ziegler,FAPESPThe vicious cycle of heart failure (HF). (i) Impaired aldehyde metabolism by aldehyde dehydrogenase 2 (ALDH2); (ii) accumulation of 4-hydroxynonenal (4-HNE), a re

Updated on: April 01,2024

Synthetic molecule proves able to mitigate heart failure in translational study

by Maria Fernanda Ziegler,FAPESPThe vicious cycle of heart failure (HF). (i) Impaired aldehyde metabolism by aldehyde dehydrogenase 2 (ALDH2); (ii) accumulation of 4-hydroxynonenal (4-HNE), a re

Updated on:April 01,2024

Researchers show potential liver cancer treatment by targeting cancer stem-like cells

by National University of SingaporeLiver cancer stem-like cells grown as tumourspheres that are sensitive to JAK/STAT small molecule inhibitors. Credit: National University of SingaporeLiver canc

Updated on: March 01,2024

Researchers show potential liver cancer treatment by targeting cancer stem-like cells

by National University of SingaporeLiver cancer stem-like cells grown as tumourspheres that are sensitive to JAK/STAT small molecule inhibitors. Credit: National University of SingaporeLiver canc

Updated on:March 01,2024

Depression linked to deadly inflammation in lung cancer patients

by Jeff Grabmeier,The Ohio State UniversityKaplan Meier survival curve for NSCLC patients stratified by NLR systemic inflammation, NLR < 5 and NLR ≥ 5 (n = 184), showing worse survival probab

Updated on: January 30,2024

Depression linked to deadly inflammation in lung cancer patients

by Jeff Grabmeier,The Ohio State UniversityKaplan Meier survival curve for NSCLC patients stratified by NLR systemic inflammation, NLR < 5 and NLR ≥ 5 (n = 184), showing worse survival probab

Updated on:January 30,2024

Doctors must stop misleading women about cervical screening

by James Dickinson,The ConversationCredit: AI-generated imageCervical screening is one of the most effective screening tests, responsible for substantial reduction in death from cervical cancer.

Updated on: May 17,2024

Doctors must stop misleading women about cervical screening

by James Dickinson,The ConversationCredit: AI-generated imageCervical screening is one of the most effective screening tests, responsible for substantial reduction in death from cervical cancer.

Updated on:May 17,2024

Revealing characteristics of circulating cell-free RNA in the blood of liver cancer patients

byScience China PressMOF materials efficiently enrich circulating nucleic acids (cfDNA and cfRNA) in blood through a simple operational process, enabling various downstream nucleic acid detectio

Updated on: March 30,2024

Revealing characteristics of circulating cell-free RNA in the blood of liver cancer patients

byScience China PressMOF materials efficiently enrich circulating nucleic acids (cfDNA and cfRNA) in blood through a simple operational process, enabling various downstream nucleic acid detectio

Updated on:March 30,2024

Target discovered for the treatment of pancreatic cancer

byKiel UniversityAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainA team at the Institute of Biochemistry at Kiel University has found a

Updated on: July 05,2024

Target discovered for the treatment of pancreatic cancer

byKiel UniversityAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainA team at the Institute of Biochemistry at Kiel University has found a

Updated on:July 05,2024

More aggressive treatment doesn't impact quality of life for metastatic colorectal cancer patients, says new study

by National Comprehensive Cancer NetworkCredit: Unsplash/CC0 Public DomainNewresearchin the October 2023 issue ofJournal of the National Comprehensive Cancer Networkfinds that

Updated on: May 21,2024

More aggressive treatment doesn't impact quality of life for metastatic colorectal cancer patients, says new study

by National Comprehensive Cancer NetworkCredit: Unsplash/CC0 Public DomainNewresearchin the October 2023 issue ofJournal of the National Comprehensive Cancer Networkfinds that

Updated on:May 21,2024

Diverticular disease associated with cancer outside gastrointestinal tract

by Karolinska InstitutetIllustration of bacteria in the human gut. Credit: Darryl Leja, National Human Genome Research Institute, National Institutes of HealthThrough the ESPRESSO cohort, researc

Updated on: February 18,2024

Diverticular disease associated with cancer outside gastrointestinal tract

by Karolinska InstitutetIllustration of bacteria in the human gut. Credit: Darryl Leja, National Human Genome Research Institute, National Institutes of HealthThrough the ESPRESSO cohort, researc

Updated on:February 18,2024

T-cell interactions vary between tumor microenvironments

by Melissa Rohman,Northwestern UniversityShown is a p-STAT3- non-reactive astrocyte (white arrow) in close proximity to a CD3+p-STAT3- T cell (blue arrow) and a CD163+p-STAT3- macrophage (red ar

Updated on: April 01,2024

T-cell interactions vary between tumor microenvironments

by Melissa Rohman,Northwestern UniversityShown is a p-STAT3- non-reactive astrocyte (white arrow) in close proximity to a CD3+p-STAT3- T cell (blue arrow) and a CD163+p-STAT3- macrophage (red ar

Updated on:April 01,2024

Second opinions from comprehensive cancer centers changed treatment plans for African-American patients

by American Association for Cancer ResearchCancer cell during cell division. Credit: National Institutes of HealthAfrican American breast cancer patients who received second opinions from an NCI-

Updated on: April 01,2024

Second opinions from comprehensive cancer centers changed treatment plans for African-American patients

by American Association for Cancer ResearchCancer cell during cell division. Credit: National Institutes of HealthAfrican American breast cancer patients who received second opinions from an NCI-

Updated on:April 01,2024