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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Clinical trial generates promising results for immunotherapy drug nivolumab in patients with advanced skin cancer

Clinical trial generates promising results for immunotherapy drug nivolumab in patients with advanced skin cancer

byWileyCredit: CC0 Public DomainNumerous studies have shown that drugs called immune checkpoint inhibitors can boost the immune system's response against various cancers. Now a phase II clin

Clinical trial generates promising results for immunotherapy drug nivolumab in patients with advanced skin cancer

byWileyCredit: CC0 Public DomainNumerous studies have shown that drugs called immune checkpoint inhibitors can boost the immune system's response against various cancers. Now a phase II clin
Researchers identify potential biomarker to distinguish two aggressive types of brain tumors in children

Researchers identify potential biomarker to distinguish two aggressive types of brain tumors in children

by Johns Hopkins University School of MedicineSMYD3 overexpression activates the EGFR pathway in CHLA01 cells. (A) Localization of endogenous SMYD3. Representative 60x Z-stack confocal images sho

Researchers identify potential biomarker to distinguish two aggressive types of brain tumors in children

by Johns Hopkins University School of MedicineSMYD3 overexpression activates the EGFR pathway in CHLA01 cells. (A) Localization of endogenous SMYD3. Representative 60x Z-stack confocal images sho
First major study of proteins in patients with acute lymphoblastic leukaemia

First major study of proteins in patients with acute lymphoblastic leukaemia

by Lund UniversityA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/WikipediaThe most common form of childhood ca

First major study of proteins in patients with acute lymphoblastic leukaemia

by Lund UniversityA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/WikipediaThe most common form of childhood ca
Investigating the immunoregulatory protein CD200 as a potentially lucrative yet elusive target for cancer therapy

Investigating the immunoregulatory protein CD200 as a potentially lucrative yet elusive target for cancer therapy

by Impact Journals LLCMultiple mechanisms underly the pro-tumorigenic role of CD200. Credit: 2023 Shao and Owens.A new research perspective titled "The immunoregulatory protein CD200 as a potenti

Investigating the immunoregulatory protein CD200 as a potentially lucrative yet elusive target for cancer therapy

by Impact Journals LLCMultiple mechanisms underly the pro-tumorigenic role of CD200. Credit: 2023 Shao and Owens.A new research perspective titled "The immunoregulatory protein CD200 as a potenti
Digital rectal examination is not useful to early detect prostate cancers, says new research

Digital rectal examination is not useful to early detect prostate cancers, says new research

by European Association of UrologyCredit: Unsplash/CC0 Public DomainA common method of detecting prostate cancer may not be accurate enough as a reliable screening tool by itself, scientists have

Digital rectal examination is not useful to early detect prostate cancers, says new research

by European Association of UrologyCredit: Unsplash/CC0 Public DomainA common method of detecting prostate cancer may not be accurate enough as a reliable screening tool by itself, scientists have
Vitamin D supplementation likely improves survival of cancers of the digestive tract, says researcher

Vitamin D supplementation likely improves survival of cancers of the digestive tract, says researcher

by Boston University School of MedicineCredit: Unsplash/CC0 Public DomainFor more than 100 years, it has been believed that sunlight and vitamin D deficiency were associated with the risk for man

Vitamin D supplementation likely improves survival of cancers of the digestive tract, says researcher

by Boston University School of MedicineCredit: Unsplash/CC0 Public DomainFor more than 100 years, it has been believed that sunlight and vitamin D deficiency were associated with the risk for man
Drinking alcohol not likely to increase risk of a breast cancer recurrence

Drinking alcohol not likely to increase risk of a breast cancer recurrence

by Kaiser PermanenteCredit: CC0 Public DomainA Kaiser Permanente study provides new information that may help oncologists answer one of the most common questions they hear from breast cancer surv

Drinking alcohol not likely to increase risk of a breast cancer recurrence

by Kaiser PermanenteCredit: CC0 Public DomainA Kaiser Permanente study provides new information that may help oncologists answer one of the most common questions they hear from breast cancer surv
Inhibition of histone deacetylase 2 reduces MDM2 expression and reduces tumor growth in dedifferentiated liposarcoma

Inhibition of histone deacetylase 2 reduces MDM2 expression and reduces tumor growth in dedifferentiated liposarcoma

by OncotargetElevated HDAC2 mRNA expression is poorly prognostic in DDLPS. (A) mRNA expression of HDAC2 and disease-free survival (DFS) data from 52 subjects with DDLPS from The Cancer Genome Atlas (T

Inhibition of histone deacetylase 2 reduces MDM2 expression and reduces tumor growth in dedifferentiated liposarcoma

by OncotargetElevated HDAC2 mRNA expression is poorly prognostic in DDLPS. (A) mRNA expression of HDAC2 and disease-free survival (DFS) data from 52 subjects with DDLPS from The Cancer Genome Atlas (T
New study brings personalized immunotherapy prescriptions a step closer

New study brings personalized immunotherapy prescriptions a step closer

byUniversity of BathCredit: Unsplash/CC0 Public DomainIn a step likely to advance personalized cancer treatment, scientists have—for the first time—shown in patients that levels of biomarkers ar

New study brings personalized immunotherapy prescriptions a step closer

byUniversity of BathCredit: Unsplash/CC0 Public DomainIn a step likely to advance personalized cancer treatment, scientists have—for the first time—shown in patients that levels of biomarkers ar
Research reveals how breast cancer gene mutations may impact cell communication

Research reveals how breast cancer gene mutations may impact cell communication

by Cleveland ClinicCredit: Pixabay/CC0 Public DomainNew Cleveland Clinic research reveals how BRCA1 and BRCA2 gene mutations may impact cell communication in breast tissue, furthering the underst

Research reveals how breast cancer gene mutations may impact cell communication

by Cleveland ClinicCredit: Pixabay/CC0 Public DomainNew Cleveland Clinic research reveals how BRCA1 and BRCA2 gene mutations may impact cell communication in breast tissue, furthering the underst
Potential therapeutic target for small cell lung cancer discovered

Potential therapeutic target for small cell lung cancer discovered

by Melissa Rohman,Northwestern UniversityGraphic model showing how POU2AF2 establishes the poised enhancer via SWI/SNF activity-dependent recruitment of the Polycomb complex in SCLC-P subtype ce

Potential therapeutic target for small cell lung cancer discovered

by Melissa Rohman,Northwestern UniversityGraphic model showing how POU2AF2 establishes the poised enhancer via SWI/SNF activity-dependent recruitment of the Polycomb complex in SCLC-P subtype ce
Experts call for a targeted approach to cancer prevention

Experts call for a targeted approach to cancer prevention

by University of StirlingCredit: CC0 Public DomainPolicymakers around the world should consider introducing more targeted early interventions in a bid to tackle cancer, according to experts at th

Experts call for a targeted approach to cancer prevention

by University of StirlingCredit: CC0 Public DomainPolicymakers around the world should consider introducing more targeted early interventions in a bid to tackle cancer, according to experts at th