Study uncovers epigenetic source of resistance to targeted therapy in EGFR-mutant lung cancer

by Dana-Farber Cancer InstituteCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.07.005When lung cancers driven by mutations in the EGFR gene become resistant to osimertinib or othe

Updated on: February 01,2024

Study uncovers epigenetic source of resistance to targeted therapy in EGFR-mutant lung cancer

by Dana-Farber Cancer InstituteCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.07.005When lung cancers driven by mutations in the EGFR gene become resistant to osimertinib or othe

Updated on:February 01,2024

Biological pathways provide evidence for how to overcome barriers limiting cancer immunotherapies

byUNC Lineberger Comprehensive Cancer CenterCredit: Unsplash/CC0 Public DomainResearchers at UNC Lineberger Comprehensive Cancer Center have found a possible way to overcome barriers that block

Updated on: January 04,2024

Biological pathways provide evidence for how to overcome barriers limiting cancer immunotherapies

byUNC Lineberger Comprehensive Cancer CenterCredit: Unsplash/CC0 Public DomainResearchers at UNC Lineberger Comprehensive Cancer Center have found a possible way to overcome barriers that block

Updated on:January 04,2024

Public unaware of cancer risk from too little exercise, study reports

by Taylor & FrancisCredit: CC0 Public DomainIt has long been accepted that regular exercise can assist in helping to prevent or reduce the risk of a multitude of health problems. However, a n

Updated on: March 08,2024

Public unaware of cancer risk from too little exercise, study reports

by Taylor & FrancisCredit: CC0 Public DomainIt has long been accepted that regular exercise can assist in helping to prevent or reduce the risk of a multitude of health problems. However, a n

Updated on:March 08,2024

Survivorship standards help address the distinct needs of adult cancer survivors

byAmerican College of SurgeonsCredit: Thirdman from PexelsWith the number of adult cancer survivors in the United States expected to reach 23 million by 2032, the long-term needs of this populat

Updated on: July 05,2024

Survivorship standards help address the distinct needs of adult cancer survivors

byAmerican College of SurgeonsCredit: Thirdman from PexelsWith the number of adult cancer survivors in the United States expected to reach 23 million by 2032, the long-term needs of this populat

Updated on:July 05,2024

Study validates clinical utility of pan-tumor predictive biomarker for checkpoint inhibitor immunotherapy benefit

by Strata OncologyDevelopment of an integrative immunotherapy response score (IRS) model to stratify PD-(L)1 therapy benefit in patients with advanced solid tumors.aReal-world treatment an

Updated on: February 03,2024

Study validates clinical utility of pan-tumor predictive biomarker for checkpoint inhibitor immunotherapy benefit

by Strata OncologyDevelopment of an integrative immunotherapy response score (IRS) model to stratify PD-(L)1 therapy benefit in patients with advanced solid tumors.aReal-world treatment an

Updated on:February 03,2024

Inhibition of ribosome biogenesis as a novel approach for multi-stage cancer treatment

by Uppsala UniversityCredit: Uppsala UniversityNearly 90 percent of all cancer patient deaths are due to metastasis. A study from Uppsala University shows that a process that allows the cells to

Updated on: May 11,2024

Inhibition of ribosome biogenesis as a novel approach for multi-stage cancer treatment

by Uppsala UniversityCredit: Uppsala UniversityNearly 90 percent of all cancer patient deaths are due to metastasis. A study from Uppsala University shows that a process that allows the cells to

Updated on:May 11,2024

Shortage of vital children's cancer drug stirs fear and outrage

by Marie McCulloughCredit: CC0 Public DomainA critical shortage of a chemotherapy used to treat most childhood cancers has galvanized oncologists and parents of sick children.The U.S.medical com

Updated on: April 07,2024

Shortage of vital children's cancer drug stirs fear and outrage

by Marie McCulloughCredit: CC0 Public DomainA critical shortage of a chemotherapy used to treat most childhood cancers has galvanized oncologists and parents of sick children.The U.S.medical com

Updated on:April 07,2024

Study links mutations in notch gene to role in B cell cancers

by Perelman School of Medicine at the University of PennsylvaniaPeripheral blood with chronic lymphocytic leukemia cells. Credit: Jon Aster, Harvard Medical SchoolNotch is one of the most frequen

Updated on: July 02,2024

Study links mutations in notch gene to role in B cell cancers

by Perelman School of Medicine at the University of PennsylvaniaPeripheral blood with chronic lymphocytic leukemia cells. Credit: Jon Aster, Harvard Medical SchoolNotch is one of the most frequen

Updated on:July 02,2024

Study reveals pathways for aggressive prostate cancer subtype

by Vanderbilt University Medical CenterScRNAseq of ICC/IDC-enriched and benign-enriched prostate. a Schematic of scRNAseq protocol of ICC/IDC-enriched and benign-enriched prostate. b Representati

Updated on: February 23,2024

Study reveals pathways for aggressive prostate cancer subtype

by Vanderbilt University Medical CenterScRNAseq of ICC/IDC-enriched and benign-enriched prostate. a Schematic of scRNAseq protocol of ICC/IDC-enriched and benign-enriched prostate. b Representati

Updated on:February 23,2024

The protein behind immunotherapy resistance

byEcole Polytechnique Federale de LausanneTumor with FMRP-deficient cancer cells (in green) being infiltrated and attached by killer (CD8) T cells. Credit: Jeremy Guillot (Hanahan Lab – EPFL).Im

Updated on: January 02,2024

The protein behind immunotherapy resistance

byEcole Polytechnique Federale de LausanneTumor with FMRP-deficient cancer cells (in green) being infiltrated and attached by killer (CD8) T cells. Credit: Jeremy Guillot (Hanahan Lab – EPFL).Im

Updated on:January 02,2024

Docs should consider a patient's weight before prescribing new chemotherapy drugs

by Sharon Parmet,University of Illinois at ChicagoAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainA new class of cancer drugs just now

Updated on: May 13,2024

Docs should consider a patient's weight before prescribing new chemotherapy drugs

by Sharon Parmet,University of Illinois at ChicagoAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainA new class of cancer drugs just now

Updated on:May 13,2024

Researchers study how altered protein degradation contributes to the development of tumors

by Institute for Research in Biomedicine (IRB Barcelona)To ensure adequate levels of proteins in the cell, a strict quality control system is responsible for tagging the proteins with ubiquitin f

Updated on: March 06,2024

Researchers study how altered protein degradation contributes to the development of tumors

by Institute for Research in Biomedicine (IRB Barcelona)To ensure adequate levels of proteins in the cell, a strict quality control system is responsible for tagging the proteins with ubiquitin f

Updated on:March 06,2024