Research raises hopes for new treatment of fusion-driven cancer

by Aarhus UniversityFusion-gene disruption strategy.ADual intron-targeting CRISPR-Cas9-mediated disruption ofRUNX1-RUNX1T1. sgRNAs targeting intron 4 ofRUNX1(orange)

Updated on: February 03,2024

Research raises hopes for new treatment of fusion-driven cancer

by Aarhus UniversityFusion-gene disruption strategy.ADual intron-targeting CRISPR-Cas9-mediated disruption ofRUNX1-RUNX1T1. sgRNAs targeting intron 4 ofRUNX1(orange)

Updated on:February 03,2024

Early genome catastrophes can cause non-smoking lung cancer

by The Korea Advanced Institute of Science and Technology (KAIST)Smoking-unrelated oncogenesis of lung cancers by gene fusions. Credit: The Korea Advanced Institute of Science and Technology (KAI

Updated on: April 20,2024

Early genome catastrophes can cause non-smoking lung cancer

by The Korea Advanced Institute of Science and Technology (KAIST)Smoking-unrelated oncogenesis of lung cancers by gene fusions. Credit: The Korea Advanced Institute of Science and Technology (KAI

Updated on:April 20,2024

Skin cancer rewires its energy systems to spread more efficiently, finds study

by Queen Mary, University of LondonDifferent modes of migration and mitochondrial metabolism.a,bOxygen consumption rate (OCR) from cells embedded in a 3D collagen I matrix (n = 

Updated on: February 18,2024

Skin cancer rewires its energy systems to spread more efficiently, finds study

by Queen Mary, University of LondonDifferent modes of migration and mitochondrial metabolism.a,bOxygen consumption rate (OCR) from cells embedded in a 3D collagen I matrix (n = 

Updated on:February 18,2024

Enzyme inhibition promotes bone formation and curbs the development of bone metastases, study finds

byGerman Cancer Research CenterNegative regulation of bone formation by TAM receptor MERTK.amRNA expression analysis of TAM receptor familyMertk,Tyro3,Axl,Gas

Updated on: January 23,2024

Enzyme inhibition promotes bone formation and curbs the development of bone metastases, study finds

byGerman Cancer Research CenterNegative regulation of bone formation by TAM receptor MERTK.amRNA expression analysis of TAM receptor familyMertk,Tyro3,Axl,Gas

Updated on:January 23,2024

Researchers make next move in the fight against ovarian cancer

by University of Arizona College of EngineeringGraphic representation of falloposcope image resolution on the University of Arizona's "Block A." Credit: University of ArizonaOvarian canc

Updated on: June 04,2024

Researchers make next move in the fight against ovarian cancer

by University of Arizona College of EngineeringGraphic representation of falloposcope image resolution on the University of Arizona's "Block A." Credit: University of ArizonaOvarian canc

Updated on:June 04,2024

An AI model reveals how the body's defense system recognizes skin cancer

byUniversity of HelsinkiMicrograph of malignant melanoma. Cytology specimen. Field stain. Credit: Nephron/WikipediaResearchers from the University of Helsinki, HUS Comprehensive Cancer Center, A

Updated on: January 02,2024

An AI model reveals how the body's defense system recognizes skin cancer

byUniversity of HelsinkiMicrograph of malignant melanoma. Cytology specimen. Field stain. Credit: Nephron/WikipediaResearchers from the University of Helsinki, HUS Comprehensive Cancer Center, A

Updated on:January 02,2024

Fighting pancreatic cancer with computers and lasers

by Anthony King,Horizon: The EU Research & Innovation MagazinePancreatic cancer cells (blue) growing as a sphere encased in membranes (red). Credit: National Cancer InstituteFaster detection

Updated on: April 06,2024

Fighting pancreatic cancer with computers and lasers

by Anthony King,Horizon: The EU Research & Innovation MagazinePancreatic cancer cells (blue) growing as a sphere encased in membranes (red). Credit: National Cancer InstituteFaster detection

Updated on:April 06,2024

Researchers identify mechanism of resistance to BRAF inhibitors in melanoma

by H. Lee Moffitt Cancer Center & Research InstituteMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Melanoma i

Updated on: June 08,2024

Researchers identify mechanism of resistance to BRAF inhibitors in melanoma

by H. Lee Moffitt Cancer Center & Research InstituteMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Melanoma i

Updated on:June 08,2024

Repurposing existing FDA-approved inhibitors may provide new treatment approach for ovarian cancer

by The Wistar InstituteCredit: The Wistar InstituteWistar researchers have found rationale for repurposing a class of antitumor compounds called HDAC inhibitors, already approved by the FDA for t

Updated on: April 07,2024

Repurposing existing FDA-approved inhibitors may provide new treatment approach for ovarian cancer

by The Wistar InstituteCredit: The Wistar InstituteWistar researchers have found rationale for repurposing a class of antitumor compounds called HDAC inhibitors, already approved by the FDA for t

Updated on:April 07,2024

Fewer lymph node operations for breast cancer patients with new prediction models

by Lund UniversityCredit: MostphotosIn recently published studies, researchers at Lund University and Skåne University Hospital in Sweden have produced new prediction models for improved personal

Updated on: March 01,2024

Fewer lymph node operations for breast cancer patients with new prediction models

by Lund UniversityCredit: MostphotosIn recently published studies, researchers at Lund University and Skåne University Hospital in Sweden have produced new prediction models for improved personal

Updated on:March 01,2024

Trends in genitourinary cancers examined in the United States

by Elana GotkineThe highest incidence rates of bladder cancer are seen in the Northeast, while the West has the highest deaths rates for prostate cancer among non-Hispanic White men, according to a st

Updated on: January 02,2024

Trends in genitourinary cancers examined in the United States

by Elana GotkineThe highest incidence rates of bladder cancer are seen in the Northeast, while the West has the highest deaths rates for prostate cancer among non-Hispanic White men, according to a st

Updated on:January 02,2024

Certain gene signaling rewires tumors after immunotherapy

by Anna Megdell,University of MichiganGraphical abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2022.12.008Researchers from the University of Michigan Rogel Cancer Center ha

Updated on: January 02,2024

Certain gene signaling rewires tumors after immunotherapy

by Anna Megdell,University of MichiganGraphical abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2022.12.008Researchers from the University of Michigan Rogel Cancer Center ha

Updated on:January 02,2024