Researchers identify mechanism of resistance to BRAF inhibitors in melanoma

by H. Lee Moffitt Cancer Center & Research InstituteMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Melanoma i

Updated on: June 08,2024

Researchers identify mechanism of resistance to BRAF inhibitors in melanoma

by H. Lee Moffitt Cancer Center & Research InstituteMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Melanoma i

Updated on:June 08,2024

Repurposing heart drugs to target cancer cells

by MRC London Institute of Medical SciencesCredit: CC0 Public DomainSenescence is a cellular stress response that results in the stable growth arrest of old and damaged cells. The past decade has reve

Updated on: April 07,2024

Repurposing heart drugs to target cancer cells

by MRC London Institute of Medical SciencesCredit: CC0 Public DomainSenescence is a cellular stress response that results in the stable growth arrest of old and damaged cells. The past decade has reve

Updated on:April 07,2024

ASCO: Pembrolizumab superior for initial Tx of advanced NSCLC

(HealthDay)—For patients with programmed death ligand 1 (PD-L1)-expressing locally advanced or metastatic non-small-cell lung cancer (NSCLC), pembrolizumab is associated with better overall survival t

Updated on: March 30,2024

ASCO: Pembrolizumab superior for initial Tx of advanced NSCLC

(HealthDay)—For patients with programmed death ligand 1 (PD-L1)-expressing locally advanced or metastatic non-small-cell lung cancer (NSCLC), pembrolizumab is associated with better overall survival t

Updated on:March 30,2024

Technique targets cancer cells and leaves healthy ones alone

by Hebrew University of JerusalemTRPV2 protein in action. Credit: Hebrew University of JerusalemIt is a feeling that many who receive a cancer diagnosis can identify with: heartbreak and fear, fo

Updated on: April 18,2024

Technique targets cancer cells and leaves healthy ones alone

by Hebrew University of JerusalemTRPV2 protein in action. Credit: Hebrew University of JerusalemIt is a feeling that many who receive a cancer diagnosis can identify with: heartbreak and fear, fo

Updated on:April 18,2024

Synthetic molecule proves able to mitigate heart failure in translational study

by Maria Fernanda Ziegler,FAPESPThe vicious cycle of heart failure (HF). (i) Impaired aldehyde metabolism by aldehyde dehydrogenase 2 (ALDH2); (ii) accumulation of 4-hydroxynonenal (4-HNE), a re

Updated on: April 01,2024

Synthetic molecule proves able to mitigate heart failure in translational study

by Maria Fernanda Ziegler,FAPESPThe vicious cycle of heart failure (HF). (i) Impaired aldehyde metabolism by aldehyde dehydrogenase 2 (ALDH2); (ii) accumulation of 4-hydroxynonenal (4-HNE), a re

Updated on:April 01,2024

Technique developed in mice could aid detection of cancer in dense breasts

by Georgetown University Medical CenterCredit: Unsplash/CC0 Public DomainA two-pronged approach to imaging breast density in mice, developed by researchers at Georgetown Lombardi Comprehensive Ca

Updated on: February 24,2024

Technique developed in mice could aid detection of cancer in dense breasts

by Georgetown University Medical CenterCredit: Unsplash/CC0 Public DomainA two-pronged approach to imaging breast density in mice, developed by researchers at Georgetown Lombardi Comprehensive Ca

Updated on:February 24,2024

Second primary malignancies represent small proportion of adverse events after CAR T-cell therapy

by Elana GotkineSecond primary malignancies (SPMs) represent a small proportion of adverse events (AEs) reported by patients receiving chimeric antigen receptor T-cell (CAR T-cell) therapy, according

Updated on: March 30,2024

Second primary malignancies represent small proportion of adverse events after CAR T-cell therapy

by Elana GotkineSecond primary malignancies (SPMs) represent a small proportion of adverse events (AEs) reported by patients receiving chimeric antigen receptor T-cell (CAR T-cell) therapy, according

Updated on:March 30,2024

Social vulnerability tied to worse pediatric head and neck cancer outcomes

by Lori SolomonAmong pediatric patients with head and neck cancers (HNCs), increasing social vulnerability is associated with significant decreases in receipt of care and survival time, according to a

Updated on: January 04,2024

Social vulnerability tied to worse pediatric head and neck cancer outcomes

by Lori SolomonAmong pediatric patients with head and neck cancers (HNCs), increasing social vulnerability is associated with significant decreases in receipt of care and survival time, according to a

Updated on:January 04,2024

Supercharging immunotherapy to stop breast cancer from spreading to the lung

byUniversity of GlasgowGraphical abstract. Credit:Journal of Experimental Medicine(2022). DOI: 10.1084/jem.20211431Breast cancer immunotherapy could be more effective if an immune ce

Updated on: January 02,2024

Supercharging immunotherapy to stop breast cancer from spreading to the lung

byUniversity of GlasgowGraphical abstract. Credit:Journal of Experimental Medicine(2022). DOI: 10.1084/jem.20211431Breast cancer immunotherapy could be more effective if an immune ce

Updated on:January 02,2024

Study shows checkpoint inhibitor prolongs survival in patients with certain head and neck cancers

by Anne Doerr,Yale UniversityCredit: stock.adobe.comThe checkpoint inhibitor pembrolizumab (Keytruda) increases the survival time of patients with advanced head and neck cancers, according to a

Updated on: May 31,2024

Study shows checkpoint inhibitor prolongs survival in patients with certain head and neck cancers

by Anne Doerr,Yale UniversityCredit: stock.adobe.comThe checkpoint inhibitor pembrolizumab (Keytruda) increases the survival time of patients with advanced head and neck cancers, according to a

Updated on:May 31,2024

Extracellular cell matrix stiffness may induce drug resistance of breast cancer cells

by Shanghai Jiao Tong University Journal CenterCredit:Mechanobiology in Medicine(2023). DOI: 10.1016/j.mbm.2023.100023A new study, led by Prof. Liu from the department of pharmacy, Univers

Updated on: April 30,2024

Extracellular cell matrix stiffness may induce drug resistance of breast cancer cells

by Shanghai Jiao Tong University Journal CenterCredit:Mechanobiology in Medicine(2023). DOI: 10.1016/j.mbm.2023.100023A new study, led by Prof. Liu from the department of pharmacy, Univers

Updated on:April 30,2024

Researchers identify women with twice the risk of cancer in both breasts

by Mayo ClinicCumulative incidence of CBC risk in PV carriers. Cumulative incidence plots for first contralateral breast cancers after primary breast cancer. Cumulative incidence is plotted again

Updated on: February 18,2024

Researchers identify women with twice the risk of cancer in both breasts

by Mayo ClinicCumulative incidence of CBC risk in PV carriers. Cumulative incidence plots for first contralateral breast cancers after primary breast cancer. Cumulative incidence is plotted again

Updated on:February 18,2024