Deep proteomic profiling reveals possible therapeutic targets for medulloblastoma

byTranslational Genomics Research InstituteSample overview and subgroup classification. (A) Common molecular alterations and subgroup classifications of 20 MB PDX models. (B) Partial least squar

Updated on: January 04,2024

Deep proteomic profiling reveals possible therapeutic targets for medulloblastoma

byTranslational Genomics Research InstituteSample overview and subgroup classification. (A) Common molecular alterations and subgroup classifications of 20 MB PDX models. (B) Partial least squar

Updated on:January 04,2024

Researchers find possible cause for chemoresistance in bowel cancer

by Martin-Luther-Universität Halle-WittenbergAnalysis of IGF2BP2 targets in tumor and metastatic CRC tissues. A, B Cumulative plot of gene expression (log2 fold change) in primary (A) and metastatic (

Updated on: January 30,2024

Researchers find possible cause for chemoresistance in bowel cancer

by Martin-Luther-Universität Halle-WittenbergAnalysis of IGF2BP2 targets in tumor and metastatic CRC tissues. A, B Cumulative plot of gene expression (log2 fold change) in primary (A) and metastatic (

Updated on:January 30,2024

Colorectal and pancreatic cancer rates up 10% in last 30 years, major study reveals

by Spink HealthCancer—Histopathologic image of colonic carcinoid. Credit: Wikipedia/CC BY-SA 3.0The results of a major study across 195 countries, presented today at UEG Week Barcelona 2019, indicate

Updated on: May 21,2024

Colorectal and pancreatic cancer rates up 10% in last 30 years, major study reveals

by Spink HealthCancer—Histopathologic image of colonic carcinoid. Credit: Wikipedia/CC BY-SA 3.0The results of a major study across 195 countries, presented today at UEG Week Barcelona 2019, indicate

Updated on:May 21,2024

Two drugs are better than one in fight against leukaemia

by FreshscienceDr Laura Eadie at work in the SAHMRI Leukaemia Research Laboratory. Credit: SAHMRIAdelaide scientists have devised a way to enhance the effectiveness of a patient's leukaemia treatm

Updated on: April 20,2024

Two drugs are better than one in fight against leukaemia

by FreshscienceDr Laura Eadie at work in the SAHMRI Leukaemia Research Laboratory. Credit: SAHMRIAdelaide scientists have devised a way to enhance the effectiveness of a patient's leukaemia treatm

Updated on:April 20,2024

Enzyme inhibition promotes bone formation and curbs the development of bone metastases, study finds

byGerman Cancer Research CenterNegative regulation of bone formation by TAM receptor MERTK.amRNA expression analysis of TAM receptor familyMertk,Tyro3,Axl,Gas

Updated on: January 23,2024

Enzyme inhibition promotes bone formation and curbs the development of bone metastases, study finds

byGerman Cancer Research CenterNegative regulation of bone formation by TAM receptor MERTK.amRNA expression analysis of TAM receptor familyMertk,Tyro3,Axl,Gas

Updated on:January 23,2024

Researchers key to advance care planning with cancer clinical trial patients

by University of Pennsylvania School of NursingConnie M. Ulrich, PhD, RN, FAAN, the Lillian S. Brunner Chair in Medical and Surgical Nursing at the University of Pennsylvania School of Nursing (P

Updated on: June 15,2024

Researchers key to advance care planning with cancer clinical trial patients

by University of Pennsylvania School of NursingConnie M. Ulrich, PhD, RN, FAAN, the Lillian S. Brunner Chair in Medical and Surgical Nursing at the University of Pennsylvania School of Nursing (P

Updated on:June 15,2024

Elegant antibody nanoparticles override immunological tolerance of tumors

by Chinese Academy of SciencesSchematic illustration of the engineered antibody nanoparticle for robust cancer immunotherapy. Credit: WANG DanggeImmune checkpoint blockade (ICB) therapy using the

Updated on: May 09,2024

Elegant antibody nanoparticles override immunological tolerance of tumors

by Chinese Academy of SciencesSchematic illustration of the engineered antibody nanoparticle for robust cancer immunotherapy. Credit: WANG DanggeImmune checkpoint blockade (ICB) therapy using the

Updated on:May 09,2024

Greater prevalence of anal cancer precursors for women living with HIV than prior reports

by Boston Medical CenterCredit: CC0 Public DomainThe prevalence of anal high-grade squamous intraepithelial lesions (HSIL), which precede anal cancer, is much higher in women living with HIV than

Updated on: May 07,2024

Greater prevalence of anal cancer precursors for women living with HIV than prior reports

by Boston Medical CenterCredit: CC0 Public DomainThe prevalence of anal high-grade squamous intraepithelial lesions (HSIL), which precede anal cancer, is much higher in women living with HIV than

Updated on:May 07,2024

A deep-learning model may help predict lung cancer survival and outcomes

by American Association for Cancer ResearchLung CA seen on CXR. Credit:CC BY-SA 4.0James Heilman, MD/WikipediaA deep-learning model developed using serial image scans of tumors from p

Updated on: May 20,2024

A deep-learning model may help predict lung cancer survival and outcomes

by American Association for Cancer ResearchLung CA seen on CXR. Credit:CC BY-SA 4.0James Heilman, MD/WikipediaA deep-learning model developed using serial image scans of tumors from p

Updated on:May 20,2024

The protein behind immunotherapy resistance

byEcole Polytechnique Federale de LausanneTumor with FMRP-deficient cancer cells (in green) being infiltrated and attached by killer (CD8) T cells. Credit: Jeremy Guillot (Hanahan Lab – EPFL).Im

Updated on: January 02,2024

The protein behind immunotherapy resistance

byEcole Polytechnique Federale de LausanneTumor with FMRP-deficient cancer cells (in green) being infiltrated and attached by killer (CD8) T cells. Credit: Jeremy Guillot (Hanahan Lab – EPFL).Im

Updated on:January 02,2024

Immune system B-cells can help predict HER2-positive breast cancer treatment response

byUNC Lineberger Comprehensive Cancer CenterThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: NCI Ce

Updated on: January 02,2024

Immune system B-cells can help predict HER2-positive breast cancer treatment response

byUNC Lineberger Comprehensive Cancer CenterThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: NCI Ce

Updated on:January 02,2024

Researchers identify novel oncogenic function for receptor linked to Alzheimer's disease

by University of TurkuCredit: CC0 Public DomainCommon and rare SORLA single nucleotide polymorphisms have been associated with the development of Alzheimer's disease. So far, SORLA has been m

Updated on: March 12,2024

Researchers identify novel oncogenic function for receptor linked to Alzheimer's disease

by University of TurkuCredit: CC0 Public DomainCommon and rare SORLA single nucleotide polymorphisms have been associated with the development of Alzheimer's disease. So far, SORLA has been m

Updated on:March 12,2024