Mapping lactylome in hepatocellular carcinoma reveals new mechanisms of metabolic adaptation

by Liu Jia,Chinese Academy of SciencesCredit: Pixabay/CC0 Public DomainLactate, a major product of glycolysis in mammals, is significantly increased in pathological states such as tumors, sepsis

Updated on: February 20,2024

Mapping lactylome in hepatocellular carcinoma reveals new mechanisms of metabolic adaptation

by Liu Jia,Chinese Academy of SciencesCredit: Pixabay/CC0 Public DomainLactate, a major product of glycolysis in mammals, is significantly increased in pathological states such as tumors, sepsis

Updated on:February 20,2024

Researchers report on ctDNA-based detection of residual disease prognostic for resected CRC

by Elana GotkineFor patients with radically resected, stage II to IV colorectal cancer (CRC), circulating tumor (ct)DNA-based detection of molecular residual disease (MRD) in response to adjuvant chem

Updated on: March 05,2024

Researchers report on ctDNA-based detection of residual disease prognostic for resected CRC

by Elana GotkineFor patients with radically resected, stage II to IV colorectal cancer (CRC), circulating tumor (ct)DNA-based detection of molecular residual disease (MRD) in response to adjuvant chem

Updated on:March 05,2024

With vibrator used in cell phones, researchers develop 3D tumor spheroids to screen for anti-cancer drugs

by Brigham and Women’s HospitalCredit:Device(2024). DOI: 10.1016/j.device.2024.100255Depending on their location, cancer cells within a three-dimensional (3D) tumor structure can have

Updated on: March 05,2024

With vibrator used in cell phones, researchers develop 3D tumor spheroids to screen for anti-cancer drugs

by Brigham and Women’s HospitalCredit:Device(2024). DOI: 10.1016/j.device.2024.100255Depending on their location, cancer cells within a three-dimensional (3D) tumor structure can have

Updated on:March 05,2024

Research reveals how breast cancer gene mutations may impact cell communication

by Cleveland ClinicCredit: Pixabay/CC0 Public DomainNew Cleveland Clinic research reveals how BRCA1 and BRCA2 gene mutations may impact cell communication in breast tissue, furthering the underst

Updated on: July 02,2024

Research reveals how breast cancer gene mutations may impact cell communication

by Cleveland ClinicCredit: Pixabay/CC0 Public DomainNew Cleveland Clinic research reveals how BRCA1 and BRCA2 gene mutations may impact cell communication in breast tissue, furthering the underst

Updated on:July 02,2024

Scrapping England's cancer plan is 'a catastrophic decision that will cost lives' warn experts

byBritish Medical JournalCredit: Pixabay/CC0 Public DomainThe UK government's proposal to roll England's long term plan for cancer into one strategy covering all major conditions, such a

Updated on: January 22,2024

Scrapping England's cancer plan is 'a catastrophic decision that will cost lives' warn experts

byBritish Medical JournalCredit: Pixabay/CC0 Public DomainThe UK government's proposal to roll England's long term plan for cancer into one strategy covering all major conditions, such a

Updated on:January 22,2024

Maternal obesity may promote liver cancer

by University of GenevaCredit:JHEP Reports(2024). DOI: 10.1016/j.jhepr.2024.101056Obesity, which could reach 50% of the population in certain developed countries by 2030, is a major p

Updated on: March 20,2024

Maternal obesity may promote liver cancer

by University of GenevaCredit:JHEP Reports(2024). DOI: 10.1016/j.jhepr.2024.101056Obesity, which could reach 50% of the population in certain developed countries by 2030, is a major p

Updated on:March 20,2024

Previously unidentified proteins suggest new way to diagnose ovarian cancer

by Nagoya UniversityExtracellular vesicles (EVs) are vesicles with lipid-bilayer structures (shown in center), and three proteins expressed on small EVs called exosomes (shown in red, green, blue

Updated on: February 23,2024

Previously unidentified proteins suggest new way to diagnose ovarian cancer

by Nagoya UniversityExtracellular vesicles (EVs) are vesicles with lipid-bilayer structures (shown in center), and three proteins expressed on small EVs called exosomes (shown in red, green, blue

Updated on:February 23,2024

An unexpected journey reveals a potent way to attack tumors

by Nancy Fliesler,Children's Hospital BostonSenescence inducer CuSO4, which causes ER stress, activates NKp46- and NKG2D-dependent NK killing, but 4-PBA, which induces senescence without ER

Updated on: February 23,2024

An unexpected journey reveals a potent way to attack tumors

by Nancy Fliesler,Children's Hospital BostonSenescence inducer CuSO4, which causes ER stress, activates NKp46- and NKG2D-dependent NK killing, but 4-PBA, which induces senescence without ER

Updated on:February 23,2024

Researchers unravel novel mechanism by which tumors grow resistant to radiotherapy

by Ludwig Institute for Cancer ResearchRalph Weichselbaum is the co-director of the Ludwig Center at Chicago. Credit: Ludwig Cancer ResearchA Ludwig Cancer Research study has uncovered a key mech

Updated on: March 12,2024

Researchers unravel novel mechanism by which tumors grow resistant to radiotherapy

by Ludwig Institute for Cancer ResearchRalph Weichselbaum is the co-director of the Ludwig Center at Chicago. Credit: Ludwig Cancer ResearchA Ludwig Cancer Research study has uncovered a key mech

Updated on:March 12,2024

Cancer deaths in Italy: Environmental pollution plays an important role

by Università di BolognaGraphical abstract. Credit:Science of The Total Environment(2022). DOI: 10.1016/j.scitotenv.2022.158439Today, cancer represents the second leading cause of death in

Updated on: February 18,2024

Cancer deaths in Italy: Environmental pollution plays an important role

by Università di BolognaGraphical abstract. Credit:Science of The Total Environment(2022). DOI: 10.1016/j.scitotenv.2022.158439Today, cancer represents the second leading cause of death in

Updated on:February 18,2024

Deep proteomic profiling reveals possible therapeutic targets for medulloblastoma

byTranslational Genomics Research InstituteSample overview and subgroup classification. (A) Common molecular alterations and subgroup classifications of 20 MB PDX models. (B) Partial least squar

Updated on: January 04,2024

Deep proteomic profiling reveals possible therapeutic targets for medulloblastoma

byTranslational Genomics Research InstituteSample overview and subgroup classification. (A) Common molecular alterations and subgroup classifications of 20 MB PDX models. (B) Partial least squar

Updated on:January 04,2024

Carcinogens found at Montana nuclear missile sites as reports of hundreds of cancers surface

by Tara CoppIn this image provided by the U.S. Air Force, Airman 1st Class Jackson Ligon, left, and Senior Airman Jonathan Marinaccio, 341st Missile Maintenance Squadron technicians connect a re-entry

Updated on: February 18,2024

Carcinogens found at Montana nuclear missile sites as reports of hundreds of cancers surface

by Tara CoppIn this image provided by the U.S. Air Force, Airman 1st Class Jackson Ligon, left, and Senior Airman Jonathan Marinaccio, 341st Missile Maintenance Squadron technicians connect a re-entry

Updated on:February 18,2024