Diabetes complications worsen prognosis for colorectal cancer patients

Complications of diabetes can have numerous negative health effects, from impaired vision and nerve damage to kidney dysfunction and heart disease. In an analysis of information on adults with colorec

Updated on: October 30,2023

Diabetes complications worsen prognosis for colorectal cancer patients

Complications of diabetes can have numerous negative health effects, from impaired vision and nerve damage to kidney dysfunction and heart disease. In an analysis of information on adults with colorec

Updated on:October 30,2023

Scientists identify potential drug target for BRCA-mutated tumours

byInstitute of Cancer ResearchCrystal structure of EXD2 exonuclease domain in spacefill format. Credit: Image generated fromPDBA new study has uncovered a previously unknown role for the e

Updated on: December 22,2023

Scientists identify potential drug target for BRCA-mutated tumours

byInstitute of Cancer ResearchCrystal structure of EXD2 exonuclease domain in spacefill format. Credit: Image generated fromPDBA new study has uncovered a previously unknown role for the e

Updated on:December 22,2023

How cancer cells die: Scientists explore new pathways of pyroptosis, killer kin of apoptosis

by Delthia Ricks , Medical XpressLymphoid BLaER1 cells undergo PANX1-dominant lysis. (A to C) BLaER1 cells were treated with topoisomerase poisons doxorubicin (2 μM) or etoposide (50 μM) for 24 hours.

Updated on: December 18,2023

How cancer cells die: Scientists explore new pathways of pyroptosis, killer kin of apoptosis

by Delthia Ricks , Medical XpressLymphoid BLaER1 cells undergo PANX1-dominant lysis. (A to C) BLaER1 cells were treated with topoisomerase poisons doxorubicin (2 μM) or etoposide (50 μM) for 24 hours.

Updated on:December 18,2023

Polygenic risk scores may miss the mark when predicting aggressive prostate cancers

by Justin Jackson , Medical XpressCredit: Pixabay/CC0 Public DomainAccording to a research letter published inJAMA Internal Medicine, prostate cancer screening frequently results in biopsies tha

Updated on: December 21,2023

Polygenic risk scores may miss the mark when predicting aggressive prostate cancers

by Justin Jackson , Medical XpressCredit: Pixabay/CC0 Public DomainAccording to a research letter published inJAMA Internal Medicine, prostate cancer screening frequently results in biopsies tha

Updated on:December 21,2023

Prozac fights deadly childhood brain cancer

by Hayley Jarvis,Brunel UniversityKiller T cells surround a cancer cell. Credit: NIHThe anti-depressant drug Prozac could be used to tackle one of the deadliest childhood tumours and possibly ot

Updated on: December 22,2023

Prozac fights deadly childhood brain cancer

by Hayley Jarvis,Brunel UniversityKiller T cells surround a cancer cell. Credit: NIHThe anti-depressant drug Prozac could be used to tackle one of the deadliest childhood tumours and possibly ot

Updated on:December 22,2023

Healthy habits could prevent 27% of cancer cases in Brazil

by Maria Fernanda Ziegler,FAPESPA study by Brazilian researchers in partnership with Harvard estimates the impact of five risk factors on the incidence of cancer- physical inactivity, unhealthy

Updated on: May 05,2024

Healthy habits could prevent 27% of cancer cases in Brazil

by Maria Fernanda Ziegler,FAPESPA study by Brazilian researchers in partnership with Harvard estimates the impact of five risk factors on the incidence of cancer- physical inactivity, unhealthy

Updated on:May 05,2024

GZ17-6.02 with bexarotene kills mycosis fungoides cells: Study

by Impact Journals LLCCombined macroautophagy and CD95 death receptor signaling facilitate additional tumor cell killing by GZ17-6.02. Credit: 2024 Booth et al.A new research paper titled "GZ17-6

Updated on: May 26,2024

GZ17-6.02 with bexarotene kills mycosis fungoides cells: Study

by Impact Journals LLCCombined macroautophagy and CD95 death receptor signaling facilitate additional tumor cell killing by GZ17-6.02. Credit: 2024 Booth et al.A new research paper titled "GZ17-6

Updated on:May 26,2024

Obesity is a risk factor for cardiotoxicity in chemotherapy-treated patients with breast cancer

byPublic Library of ScienceObesity is associated with a three-fold increased risk of cardiotoxicity in chemotherapy-treated patients with early-stage breast cancer, regardless of other predictor

Updated on: December 22,2023

Obesity is a risk factor for cardiotoxicity in chemotherapy-treated patients with breast cancer

byPublic Library of ScienceObesity is associated with a three-fold increased risk of cardiotoxicity in chemotherapy-treated patients with early-stage breast cancer, regardless of other predictor

Updated on:December 22,2023

NELSON trial protocol more sensitive than NLST and may increase the benefits of lung cancer screening

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainThe protocol used to screen and detect lung cancer in the NELSON Trial is more sensitive than the protocol use

Updated on: December 18,2023

NELSON trial protocol more sensitive than NLST and may increase the benefits of lung cancer screening

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainThe protocol used to screen and detect lung cancer in the NELSON Trial is more sensitive than the protocol use

Updated on:December 18,2023

Olaparib maintenance extends PFS by estimated three years in advanced ovarian cancer

byEuropean Society for Medical OncologyTwo-year maintenance therapy with olaparib, a PARP (poly ADP ribose polymerase) inhibitor, olaparib, led to a substantial, unprecedented improvement in pro

Updated on: December 18,2023

Olaparib maintenance extends PFS by estimated three years in advanced ovarian cancer

byEuropean Society for Medical OncologyTwo-year maintenance therapy with olaparib, a PARP (poly ADP ribose polymerase) inhibitor, olaparib, led to a substantial, unprecedented improvement in pro

Updated on:December 18,2023

Researchers test previously approved FDA drugs to treat Lowe syndrome

by Purdue UniversityR. Claudio Aguilar, a Purdue University researcher, has developed a patented therapeutic strategy for Lowe syndrome by repurposing two drugs previously approved by the U.S. Fo

Updated on: May 26,2024

Researchers test previously approved FDA drugs to treat Lowe syndrome

by Purdue UniversityR. Claudio Aguilar, a Purdue University researcher, has developed a patented therapeutic strategy for Lowe syndrome by repurposing two drugs previously approved by the U.S. Fo

Updated on:May 26,2024

How dangerous is it for lung cancer patients to skip radiation treatments?

by Cara MurezAs doctors work toward developing more personalized cancer care, a new study looks at whether lung cancer patients can miss a few days of radiation treatment and make them up with a highe

Updated on: December 22,2023

How dangerous is it for lung cancer patients to skip radiation treatments?

by Cara MurezAs doctors work toward developing more personalized cancer care, a new study looks at whether lung cancer patients can miss a few days of radiation treatment and make them up with a highe

Updated on:December 22,2023