Cellular origins of pediatric brain tumors identified

by McGill UniversityCredit: CC0 Public DomainA research team led by Dr. Claudia Kleinman, an investigator at the Lady Davis Institute at the Jewish General Hospital, together with Dr. Nada Jabado

Updated on: March 12,2024 12

Cellular origins of pediatric brain tumors identified

by McGill UniversityCredit: CC0 Public DomainA research team led by Dr. Claudia Kleinman, an investigator at the Lady Davis Institute at the Jewish General Hospital, together with Dr. Nada Jabado

Updated on:March 12,2024 12

Second primary malignancies represent small proportion of adverse events after CAR T-cell therapy

by Elana GotkineSecond primary malignancies (SPMs) represent a small proportion of adverse events (AEs) reported by patients receiving chimeric antigen receptor T-cell (CAR T-cell) therapy, according

Updated on: March 30,2024 0

Second primary malignancies represent small proportion of adverse events after CAR T-cell therapy

by Elana GotkineSecond primary malignancies (SPMs) represent a small proportion of adverse events (AEs) reported by patients receiving chimeric antigen receptor T-cell (CAR T-cell) therapy, according

Updated on:March 30,2024 0

New review on p53 biology and reactivation in blood cancers

byKarolinska InstitutetA simplified scheme of p53 regulation in cells upon stress and the drugs currently evaluated in clinical trials for p53 reactivation for improved therapy in MDS and AML. C

Updated on: March 30,2024 0

New review on p53 biology and reactivation in blood cancers

byKarolinska InstitutetA simplified scheme of p53 regulation in cells upon stress and the drugs currently evaluated in clinical trials for p53 reactivation for improved therapy in MDS and AML. C

Updated on:March 30,2024 0

Link between sphingolipids and complement signaling may be key to stopping cancer metastasis

by Caroline Wallace,Medical University of South CarolinaGraphical Abstract. Credit:Cell Reports(2022). DOI: 10.1016/j.celrep.2022.111742MUSC Hollings Cancer Center researchers have i

Updated on: January 02,2024 9

Link between sphingolipids and complement signaling may be key to stopping cancer metastasis

by Caroline Wallace,Medical University of South CarolinaGraphical Abstract. Credit:Cell Reports(2022). DOI: 10.1016/j.celrep.2022.111742MUSC Hollings Cancer Center researchers have i

Updated on:January 02,2024 9

Researchers identify hallmarks to improving pancreatic cancer therapy

by University of California, IrvineInitiation and progression of pancreatic cancer. Pancreatic ductal adenocarcinoma (PDAC) forms from the exocrine tissue of the pancreas. Acinar and ductal cells

Updated on: February 01,2024 19

Researchers identify hallmarks to improving pancreatic cancer therapy

by University of California, IrvineInitiation and progression of pancreatic cancer. Pancreatic ductal adenocarcinoma (PDAC) forms from the exocrine tissue of the pancreas. Acinar and ductal cells

Updated on:February 01,2024 19

New imaging technology for diagnosing and treating bowel cancer patients

byUniversity of GlasgowRepresentative transverse PET images from each mouse model and tracer. Credit:Clinical Cancer Research(2024). DOI: 10.1158/1078-0432.CCR-23-1063Biopsies are cu

Updated on: March 30,2024 0

New imaging technology for diagnosing and treating bowel cancer patients

byUniversity of GlasgowRepresentative transverse PET images from each mouse model and tracer. Credit:Clinical Cancer Research(2024). DOI: 10.1158/1078-0432.CCR-23-1063Biopsies are cu

Updated on:March 30,2024 0

Better adenoma detection using a molecular marker for fluorescent imaging

by Sarah E. Glass,Vanderbilt University(a)Representative white light and corresponding fluorescence colonoscopy images (static) of B6;129 mice bearing either colorectal adenomas or normal

Updated on: February 18,2024 17

Better adenoma detection using a molecular marker for fluorescent imaging

by Sarah E. Glass,Vanderbilt University(a)Representative white light and corresponding fluorescence colonoscopy images (static) of B6;129 mice bearing either colorectal adenomas or normal

Updated on:February 18,2024 17

Survival similar for Black, White prostate cancer patients in clinical trial setting

by Elana GotkineFor metastatic castration-sensitive prostate cancer (mCSPC), overall survival and progression-free survival are similar for Black and White patients receiving first- or second-generati

Updated on: February 03,2024 15

Survival similar for Black, White prostate cancer patients in clinical trial setting

by Elana GotkineFor metastatic castration-sensitive prostate cancer (mCSPC), overall survival and progression-free survival are similar for Black and White patients receiving first- or second-generati

Updated on:February 03,2024 15

T-cell interactions vary between tumor microenvironments

by Melissa Rohman,Northwestern UniversityShown is a p-STAT3- non-reactive astrocyte (white arrow) in close proximity to a CD3+p-STAT3- T cell (blue arrow) and a CD163+p-STAT3- macrophage (red ar

Updated on: April 01,2024 0

T-cell interactions vary between tumor microenvironments

by Melissa Rohman,Northwestern UniversityShown is a p-STAT3- non-reactive astrocyte (white arrow) in close proximity to a CD3+p-STAT3- T cell (blue arrow) and a CD163+p-STAT3- macrophage (red ar

Updated on:April 01,2024 0

Molecule Linking Cancer Driver and Cell Death Genes May Be Effective Against DLBCL

November 2023Thomas R. CollinsMolecules that link cancer driver genes and promoters of cell death genes produce potent killing of diffuse large B-cell lymphoma (DLBCL) cells, according to findings pub

Updated on: February 18,2024 12

Molecule Linking Cancer Driver and Cell Death Genes May Be Effective Against DLBCL

November 2023Thomas R. CollinsMolecules that link cancer driver genes and promoters of cell death genes produce potent killing of diffuse large B-cell lymphoma (DLBCL) cells, according to findings pub

Updated on:February 18,2024 12

Researchers identify one driver of melanoma spread

by Amy Mone,Johns Hopkins UniversityCredit: AI-generated imageUsing a small noncoding RNA, microRNA 211, and tools that track the stability and decay of the protein-coding and noncoding RNAs in

Updated on: June 22,2024 5

Researchers identify one driver of melanoma spread

by Amy Mone,Johns Hopkins UniversityCredit: AI-generated imageUsing a small noncoding RNA, microRNA 211, and tools that track the stability and decay of the protein-coding and noncoding RNAs in

Updated on:June 22,2024 5

Genomic deletions explain why some types of melanoma resist targeted therapies

byCenter for Genomic RegulationCredit: CC0 Public DomainMelanoma is the deadliest form of skin cancer. With global incidence rates rising, new, more effective treatments are necessary to allevia

Updated on: April 28,2024 0

Genomic deletions explain why some types of melanoma resist targeted therapies

byCenter for Genomic RegulationCredit: CC0 Public DomainMelanoma is the deadliest form of skin cancer. With global incidence rates rising, new, more effective treatments are necessary to allevia

Updated on:April 28,2024 0