Research raises hopes for new treatment of fusion-driven cancer

by Aarhus UniversityFusion-gene disruption strategy.ADual intron-targeting CRISPR-Cas9-mediated disruption ofRUNX1-RUNX1T1. sgRNAs targeting intron 4 ofRUNX1(orange)

Updated on: February 03,2024

Research raises hopes for new treatment of fusion-driven cancer

by Aarhus UniversityFusion-gene disruption strategy.ADual intron-targeting CRISPR-Cas9-mediated disruption ofRUNX1-RUNX1T1. sgRNAs targeting intron 4 ofRUNX1(orange)

Updated on:February 03,2024

Immunotherapy was meant to defeat cancer—what happened to the great promise?

by Jonathan Fisher,The ConversationCredit: Ivan Samkov from PexelsIn 1893, theAmerican Journal of the Medical Sciencesreported on 10 patients whose large and hitherto incurable cance

Updated on: November 10,2024

Immunotherapy was meant to defeat cancer—what happened to the great promise?

by Jonathan Fisher,The ConversationCredit: Ivan Samkov from PexelsIn 1893, theAmerican Journal of the Medical Sciencesreported on 10 patients whose large and hitherto incurable cance

Updated on:November 10,2024

New molecular blocker halts breast cancer metastasis, says study

byBar-Ilan UniversityA cell-permeable peptide derived from the second proline-rich region of Pyk2 blocks spontaneous lung metastasis in an immune-competent xenograft mouse model. Credit:On

Updated on: January 16,2024

New molecular blocker halts breast cancer metastasis, says study

byBar-Ilan UniversityA cell-permeable peptide derived from the second proline-rich region of Pyk2 blocks spontaneous lung metastasis in an immune-competent xenograft mouse model. Credit:On

Updated on:January 16,2024

Potential therapeutic target for small cell lung cancer discovered

by Melissa Rohman,Northwestern UniversityGraphic model showing how POU2AF2 establishes the poised enhancer via SWI/SNF activity-dependent recruitment of the Polycomb complex in SCLC-P subtype ce

Updated on: April 28,2024

Potential therapeutic target for small cell lung cancer discovered

by Melissa Rohman,Northwestern UniversityGraphic model showing how POU2AF2 establishes the poised enhancer via SWI/SNF activity-dependent recruitment of the Polycomb complex in SCLC-P subtype ce

Updated on:April 28,2024

Researchers describe a molecular strategy that helps prevent tumour formation in mice

by The Spanish National Cancer Research CentreCredit: CNIOThe body's process for manufacturing fatty acids is regulated by the enzyme FASN. In normal cells, this is not a very active process—

Updated on: June 08,2024

Researchers describe a molecular strategy that helps prevent tumour formation in mice

by The Spanish National Cancer Research CentreCredit: CNIOThe body's process for manufacturing fatty acids is regulated by the enzyme FASN. In normal cells, this is not a very active process—

Updated on:June 08,2024

A machine learning-based algorithm to predict which cancer patients benefit from immunotherapy

by Institute for Research in Biomedicine (IRB Barcelona)Credit: CC0 Public DomainScientists at the Institute for Research in Biomedicine (IRB Barcelona), in collaboration with the Centre for Geno

Updated on: May 20,2024

A machine learning-based algorithm to predict which cancer patients benefit from immunotherapy

by Institute for Research in Biomedicine (IRB Barcelona)Credit: CC0 Public DomainScientists at the Institute for Research in Biomedicine (IRB Barcelona), in collaboration with the Centre for Geno

Updated on:May 20,2024

A step toward understanding gastric cancer

by Sanjay Mishra,Vanderbilt UniversityHistopathology of Helicobacter pylori infection in a gastric foveolar pit demonstrated in endoscopic gastric biopsy. Credit: Wikipedia.Helicobacter pylori&n

Updated on: April 18,2024

A step toward understanding gastric cancer

by Sanjay Mishra,Vanderbilt UniversityHistopathology of Helicobacter pylori infection in a gastric foveolar pit demonstrated in endoscopic gastric biopsy. Credit: Wikipedia.Helicobacter pylori&n

Updated on:April 18,2024

Study reveals pathways for aggressive prostate cancer subtype

by Vanderbilt University Medical CenterScRNAseq of ICC/IDC-enriched and benign-enriched prostate. a Schematic of scRNAseq protocol of ICC/IDC-enriched and benign-enriched prostate. b Representati

Updated on: February 23,2024

Study reveals pathways for aggressive prostate cancer subtype

by Vanderbilt University Medical CenterScRNAseq of ICC/IDC-enriched and benign-enriched prostate. a Schematic of scRNAseq protocol of ICC/IDC-enriched and benign-enriched prostate. b Representati

Updated on:February 23,2024

Tumour removal with a cancer cell clear margin

by CORDISCredit: Benjamin Franklin PierceA biopsy reporting that cancer cells are still in the margin indicates a likelihood of cancer cells remaining in the body. An EU-funded project, IMAGINE,

Updated on: March 01,2024

Tumour removal with a cancer cell clear margin

by CORDISCredit: Benjamin Franklin PierceA biopsy reporting that cancer cells are still in the margin indicates a likelihood of cancer cells remaining in the body. An EU-funded project, IMAGINE,

Updated on:March 01,2024

Merck, Moderna detail potential skin cancer vaccine progress

by Tom MurphyA sign marks an entrance to a Moderna building in Cambridge, Mass., on Monday, May 18, 2020. Shares of Merck and Moderna jumped early Tuesday, Dec. 13, 2022, after the drugmakers said a p

Updated on: January 02,2024

Merck, Moderna detail potential skin cancer vaccine progress

by Tom MurphyA sign marks an entrance to a Moderna building in Cambridge, Mass., on Monday, May 18, 2020. Shares of Merck and Moderna jumped early Tuesday, Dec. 13, 2022, after the drugmakers said a p

Updated on:January 02,2024

Health insurance premiums dropped? Not so fast

by E.J. Antoni, The Heritage FoundationCredit: Pixabay/CC0 Public DomainThe latest Consumer Price Index report showed inflation slowing in October, due in part to a supposed 34% drop in the cost of he

Updated on: May 17,2024

Health insurance premiums dropped? Not so fast

by E.J. Antoni, The Heritage FoundationCredit: Pixabay/CC0 Public DomainThe latest Consumer Price Index report showed inflation slowing in October, due in part to a supposed 34% drop in the cost of he

Updated on:May 17,2024

11 percent of cancers detected via emergency visit

About 11 percent of cancers are diagnosed following an emergency department visit, according to a study presented at the 12th AACR Conference on The Science of Cancer Health Disparities in Racial/Ethn

Updated on: March 14,2024

11 percent of cancers detected via emergency visit

About 11 percent of cancers are diagnosed following an emergency department visit, according to a study presented at the 12th AACR Conference on The Science of Cancer Health Disparities in Racial/Ethn

Updated on:March 14,2024