Deep proteomic profiling reveals possible therapeutic targets for medulloblastoma

byTranslational Genomics Research InstituteSample overview and subgroup classification. (A) Common molecular alterations and subgroup classifications of 20 MB PDX models. (B) Partial least squar

Updated on: January 04,2024

Deep proteomic profiling reveals possible therapeutic targets for medulloblastoma

byTranslational Genomics Research InstituteSample overview and subgroup classification. (A) Common molecular alterations and subgroup classifications of 20 MB PDX models. (B) Partial least squar

Updated on:January 04,2024

Investigators reveal changes to immune status in patient tumors after radiation

by Roswell Park Comprehensive Cancer CenterCredit: Pixabay/CC0 Public DomainLittle is known about how radiation therapy to kill cancer cells affects immune cells and other components of patient tumors

Updated on: January 30,2024

Investigators reveal changes to immune status in patient tumors after radiation

by Roswell Park Comprehensive Cancer CenterCredit: Pixabay/CC0 Public DomainLittle is known about how radiation therapy to kill cancer cells affects immune cells and other components of patient tumors

Updated on:January 30,2024

Novel immune inhibitor associated with glioma progression

by Melissa Rohman,Northwestern UniversityCAFs are enriched in pediatric HGG relative to LGG and NB. (A) UMAP clustering from 21 pediatric brain samples . (B) The frequency of CAFs is a function

Updated on: March 30,2024

Novel immune inhibitor associated with glioma progression

by Melissa Rohman,Northwestern UniversityCAFs are enriched in pediatric HGG relative to LGG and NB. (A) UMAP clustering from 21 pediatric brain samples . (B) The frequency of CAFs is a function

Updated on:March 30,2024

Researchers explore why patients don't follow up with their doctors after receiving a positive colorectal cancer test

by American Academy of Family PhysiciansReasons for no colonoscopy after an unfavorable screening result in Dutch colorectal cancer screening: a nation-wise questionnaire. Credit:The Annals

Updated on: February 01,2024

Researchers explore why patients don't follow up with their doctors after receiving a positive colorectal cancer test

by American Academy of Family PhysiciansReasons for no colonoscopy after an unfavorable screening result in Dutch colorectal cancer screening: a nation-wise questionnaire. Credit:The Annals

Updated on:February 01,2024

Study suggests tumor mutational load may be useful metric to predict response to checkpoint-inhibitor immunotherapy

by Bob Yirka , Medical XpressCredit: CC0 Public DomainA large team of researchers affiliated with Sloan Kettering Cancer Center, Weill Cornell Medical Center and Columbia University Medical Center has

Updated on: March 08,2024

Study suggests tumor mutational load may be useful metric to predict response to checkpoint-inhibitor immunotherapy

by Bob Yirka , Medical XpressCredit: CC0 Public DomainA large team of researchers affiliated with Sloan Kettering Cancer Center, Weill Cornell Medical Center and Columbia University Medical Center has

Updated on:March 08,2024

Severe herpesvirus infection beats adult T-cell leukemia/lymphoma

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainIn a recently published editorial in the journalGenes & Cancer, researcher Tatsuro Jo from the Japanese Red Cross Nagasaki Genbaku Hosp

Updated on: January 16,2024

Severe herpesvirus infection beats adult T-cell leukemia/lymphoma

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainIn a recently published editorial in the journalGenes & Cancer, researcher Tatsuro Jo from the Japanese Red Cross Nagasaki Genbaku Hosp

Updated on:January 16,2024

Colorectal and pancreatic cancer rates up 10% in last 30 years, major study reveals

by Spink HealthCancer—Histopathologic image of colonic carcinoid. Credit: Wikipedia/CC BY-SA 3.0The results of a major study across 195 countries, presented today at UEG Week Barcelona 2019, indicate

Updated on: May 21,2024

Colorectal and pancreatic cancer rates up 10% in last 30 years, major study reveals

by Spink HealthCancer—Histopathologic image of colonic carcinoid. Credit: Wikipedia/CC BY-SA 3.0The results of a major study across 195 countries, presented today at UEG Week Barcelona 2019, indicate

Updated on:May 21,2024

Even with multiple breast tumors, mastectomy isn't always necessary: Study

by Denise MannSome women with multiple breast tumors can safely be spared breast removal surgery, choosing less invasive treatment instead, new research suggests.Under certain conditions,women&n

Updated on: January 16,2024

Even with multiple breast tumors, mastectomy isn't always necessary: Study

by Denise MannSome women with multiple breast tumors can safely be spared breast removal surgery, choosing less invasive treatment instead, new research suggests.Under certain conditions,women&n

Updated on:January 16,2024

T-cell interactions vary between tumor microenvironments

by Melissa Rohman,Northwestern UniversityShown is a p-STAT3- non-reactive astrocyte (white arrow) in close proximity to a CD3+p-STAT3- T cell (blue arrow) and a CD163+p-STAT3- macrophage (red ar

Updated on: April 01,2024

T-cell interactions vary between tumor microenvironments

by Melissa Rohman,Northwestern UniversityShown is a p-STAT3- non-reactive astrocyte (white arrow) in close proximity to a CD3+p-STAT3- T cell (blue arrow) and a CD163+p-STAT3- macrophage (red ar

Updated on:April 01,2024

New reports examine COVID's radiotherapy interruption implications

by University of Tennessee Health Science Center(A-D) Major radiation therapy (RT) interruption rates before and during the pandemic mapped by ZIP code across the metropolitan region by race and insur

Updated on: January 11,2024

New reports examine COVID's radiotherapy interruption implications

by University of Tennessee Health Science Center(A-D) Major radiation therapy (RT) interruption rates before and during the pandemic mapped by ZIP code across the metropolitan region by race and insur

Updated on:January 11,2024

Microbial signature of colorectal cancer-associated mutations identified

by American Society for MicrobiologyCredit: CC0 Public DomainFor about 40% of people diagnosed with colorectal cancer (CRC), the tumor carries a mutation in a gene called KRAS. Many of those muta

Updated on: April 06,2024

Microbial signature of colorectal cancer-associated mutations identified

by American Society for MicrobiologyCredit: CC0 Public DomainFor about 40% of people diagnosed with colorectal cancer (CRC), the tumor carries a mutation in a gene called KRAS. Many of those muta

Updated on:April 06,2024

Reconsidering oxygen's role in growth of tumors

byYale UniversityGraphical abstract. Credit:Cell Systems(2022). DOI: 10.1016/j.cels.2022.11.003Yale researchers have made a discovery that changes conventional thinking about the rol

Updated on: January 22,2024

Reconsidering oxygen's role in growth of tumors

byYale UniversityGraphical abstract. Credit:Cell Systems(2022). DOI: 10.1016/j.cels.2022.11.003Yale researchers have made a discovery that changes conventional thinking about the rol

Updated on:January 22,2024