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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Trial demonstrates acute lymphoblastic leukemia treatment advance

Trial demonstrates acute lymphoblastic leukemia treatment advance

by Diane Dragaud, ECOG-ACRIN Cancer Research GroupCredit:LBA-1 Consolidation Therapy with Blinatumomab Improves Overall Survival in Newly Diagnosed Adult Patients with B-Lineage Acute Lymphoblas

Trial demonstrates acute lymphoblastic leukemia treatment advance

by Diane Dragaud, ECOG-ACRIN Cancer Research GroupCredit:LBA-1 Consolidation Therapy with Blinatumomab Improves Overall Survival in Newly Diagnosed Adult Patients with B-Lineage Acute Lymphoblas
Protective mutation shown to impair esophagus tumor growth

Protective mutation shown to impair esophagus tumor growth

byWellcome Trust Sanger InstituteDifferentiation and homeostasis in aged Notch1 mutant mouse tissue. a, YFPCreNotch1flox/floxmice were induced at high dose so mutant cells rapidly covered

Protective mutation shown to impair esophagus tumor growth

byWellcome Trust Sanger InstituteDifferentiation and homeostasis in aged Notch1 mutant mouse tissue. a, YFPCreNotch1flox/floxmice were induced at high dose so mutant cells rapidly covered
Universal genetic testing may improve risk stratification and treatment for rare and lethal cancer

Universal genetic testing may improve risk stratification and treatment for rare and lethal cancer

Esophageal adenocarcinoma (EAC) is a highly lethal cancer, with a five-year survival rate of less than 20 percent. Although a precursor lesion to EAC, called Barrett's esophagus (BE), is present i

Universal genetic testing may improve risk stratification and treatment for rare and lethal cancer

Esophageal adenocarcinoma (EAC) is a highly lethal cancer, with a five-year survival rate of less than 20 percent. Although a precursor lesion to EAC, called Barrett's esophagus (BE), is present i
Trazadone and CBT no more effective than placebo for improving insomnia among long-term dialysis patients, finds study

Trazadone and CBT no more effective than placebo for improving insomnia among long-term dialysis patients, finds study

by American College of PhysiciansCredit: Unsplash/CC0 Public DomainA clinical trial of more than 120 persons undergoing hemodialysis found that cognitive behavioral therapy for insomnia (CBT-I) o

Trazadone and CBT no more effective than placebo for improving insomnia among long-term dialysis patients, finds study

by American College of PhysiciansCredit: Unsplash/CC0 Public DomainA clinical trial of more than 120 persons undergoing hemodialysis found that cognitive behavioral therapy for insomnia (CBT-I) o
Personalised blood test could help predict which lung cancers might return

Personalised blood test could help predict which lung cancers might return

byGraeme Sneddon| News1 April 2022Patients who are at a higher risk of their lung cancer returning can be identified by a personalised blood test that is performed after treatment, accordi

Personalised blood test could help predict which lung cancers might return

byGraeme Sneddon| News1 April 2022Patients who are at a higher risk of their lung cancer returning can be identified by a personalised blood test that is performed after treatment, accordi
Potential new treatment for angioimmunoblastic T-cell lymphoma

Potential new treatment for angioimmunoblastic T-cell lymphoma

byUniversity of TsukubaCredit: AI-generated imageA type of blood cell cancer called angioimmunoblastic T-cell lymphoma (AITL) can develop as mutations accumulate with age in the stem cells from

Potential new treatment for angioimmunoblastic T-cell lymphoma

byUniversity of TsukubaCredit: AI-generated imageA type of blood cell cancer called angioimmunoblastic T-cell lymphoma (AITL) can develop as mutations accumulate with age in the stem cells from
Machine-learning tool to match treatment for cancer patients

Machine-learning tool to match treatment for cancer patients

byTechnion - Israel Institute of TechnologySummary of pipeline predictions. a An overview of the RNA-MuTect-WMN pipeline: In the training set (n = 100, green arrows), RNA-MuTect is applied on tu

Machine-learning tool to match treatment for cancer patients

byTechnion - Israel Institute of TechnologySummary of pipeline predictions. a An overview of the RNA-MuTect-WMN pipeline: In the training set (n = 100, green arrows), RNA-MuTect is applied on tu
Multi-center study sheds light on understudied breast cancer type

Multi-center study sheds light on understudied breast cancer type

byUniversity of PittsburghCredit: Pixabay/CC0 Public DomainA multi-center analysis of patients with invasive lobular carcinoma, or ILC—the second most common histological subtype of invasive bre

Multi-center study sheds light on understudied breast cancer type

byUniversity of PittsburghCredit: Pixabay/CC0 Public DomainA multi-center analysis of patients with invasive lobular carcinoma, or ILC—the second most common histological subtype of invasive bre
Mapping oesophageal cancer genes leads to new drug targets

Mapping oesophageal cancer genes leads to new drug targets

byCancer Research UK| News4 February 2019Mutations that cause oesophageal adenocarcinoma (OAC) have been mapped in unprecedented detail – unveiling that more than half could be targeted by

Mapping oesophageal cancer genes leads to new drug targets

byCancer Research UK| News4 February 2019Mutations that cause oesophageal adenocarcinoma (OAC) have been mapped in unprecedented detail – unveiling that more than half could be targeted by
Multimodal genomic analyses predict response to immunotherapy in lung cancer patients

Multimodal genomic analyses predict response to immunotherapy in lung cancer patients

by Amy Mone,Johns Hopkins University School of MedicineLung cancer. Credit: Jennifer Fairman and Valsamo Anagnostou, Johns Hopkins UniversityResearchers at Johns Hopkins Kimmel Cancer Center, th

Multimodal genomic analyses predict response to immunotherapy in lung cancer patients

by Amy Mone,Johns Hopkins University School of MedicineLung cancer. Credit: Jennifer Fairman and Valsamo Anagnostou, Johns Hopkins UniversityResearchers at Johns Hopkins Kimmel Cancer Center, th
Improving treatment for hairy cell leukemia

Improving treatment for hairy cell leukemia

by Melissa Rohman,Northwestern UniversityCredit: Unsplash/CC0 Public DomainPatients with relapsed or refractory hairy cell leukemia who were treated with vemurafenib experienced excellent respon

Improving treatment for hairy cell leukemia

by Melissa Rohman,Northwestern UniversityCredit: Unsplash/CC0 Public DomainPatients with relapsed or refractory hairy cell leukemia who were treated with vemurafenib experienced excellent respon