Encyclopedic tumor analysis for guiding treatment of advanced, broadly refractory cancers

by OncotargetCONSORT diagram. Credit: Ajay SrinivasanRESILIENT was a single arm, open label, phase II/III study to test if label agnostic therapy regimens guided by Encyclopedic Tumor Analysis can off

Updated on: May 09,2024 4

Encyclopedic tumor analysis for guiding treatment of advanced, broadly refractory cancers

by OncotargetCONSORT diagram. Credit: Ajay SrinivasanRESILIENT was a single arm, open label, phase II/III study to test if label agnostic therapy regimens guided by Encyclopedic Tumor Analysis can off

Updated on:May 09,2024 4

Primary pancreatic organoid tumor models for high-throughput phenotypic drug screening

by SLAS (Society for Laboratory Automation and Screening)A Z-stack image was obtained after staining nuclei with Hoechst using confocal microscopy at 5 micron intervals and then assembled using ImageJ

Updated on: May 09,2024 6

Primary pancreatic organoid tumor models for high-throughput phenotypic drug screening

by SLAS (Society for Laboratory Automation and Screening)A Z-stack image was obtained after staining nuclei with Hoechst using confocal microscopy at 5 micron intervals and then assembled using ImageJ

Updated on:May 09,2024 6

Discovering cancers of epigenetic origin without DNA mutation

byCNRSExample of a tumor obtained by reducing the expression levels of a Polycomb protein. On the left is an example of precursor tissue of the eye during normal development. On the right, a tum

Updated on: April 28,2024 0

Discovering cancers of epigenetic origin without DNA mutation

byCNRSExample of a tumor obtained by reducing the expression levels of a Polycomb protein. On the left is an example of precursor tissue of the eye during normal development. On the right, a tum

Updated on:April 28,2024 0

Taking a closer look at eye cancer: Research offers new insight into high rate of metastasis

byEdith Cowan UniversityCredit: Marc Schulte from PexelsNew research from Edith Cowan University (ECU) is one step closer to understanding why uveal melanoma, the deadliest form of eye cancer, h

Updated on: August 01,2024 0

Taking a closer look at eye cancer: Research offers new insight into high rate of metastasis

byEdith Cowan UniversityCredit: Marc Schulte from PexelsNew research from Edith Cowan University (ECU) is one step closer to understanding why uveal melanoma, the deadliest form of eye cancer, h

Updated on:August 01,2024 0

Latest results from clinical trial show patients with advanced HER2-positive breast cancer live longer on pyrotinib

by Associação Advanced Breast Cancer Global AllianceCredit: Unsplash/CC0 Public DomainPatients with HER2-positive breast cancer that has started to spread to other parts of the body survive for longer

Updated on: April 18,2024 0

Latest results from clinical trial show patients with advanced HER2-positive breast cancer live longer on pyrotinib

by Associação Advanced Breast Cancer Global AllianceCredit: Unsplash/CC0 Public DomainPatients with HER2-positive breast cancer that has started to spread to other parts of the body survive for longer

Updated on:April 18,2024 0

Genetic variation linked to cognitive differences after radiation for pediatric medulloblastoma

by Emory UniversityAlthough clinicians have aimed at reducing doses of radiotherapy to lessen long-term impairment in medulloblastoma patients, research thus far has shown that lower doses lead t

Updated on: May 13,2024 7

Genetic variation linked to cognitive differences after radiation for pediatric medulloblastoma

by Emory UniversityAlthough clinicians have aimed at reducing doses of radiotherapy to lessen long-term impairment in medulloblastoma patients, research thus far has shown that lower doses lead t

Updated on:May 13,2024 7

New combination blood test for pancreatic cancer may catch disease earlier

by Van Andel Research InstituteDr. Brian Haab. Credit: Van Andel Research InstituteA new approach to pancreatic cancer screening may help doctors detect the disease in people at high risk before

Updated on: May 13,2024 5

New combination blood test for pancreatic cancer may catch disease earlier

by Van Andel Research InstituteDr. Brian Haab. Credit: Van Andel Research InstituteA new approach to pancreatic cancer screening may help doctors detect the disease in people at high risk before

Updated on:May 13,2024 5

Researchers describe a mechanism inducing self-killing of cancer cells

by The Korea Advanced Institute of Science and Technology (KAIST)Professor Kim (left) and lead author Lee. Credit: The Korea Advanced Institute of Science and Technology (KAIST)Researchers have d

Updated on: June 08,2024 3

Researchers describe a mechanism inducing self-killing of cancer cells

by The Korea Advanced Institute of Science and Technology (KAIST)Professor Kim (left) and lead author Lee. Credit: The Korea Advanced Institute of Science and Technology (KAIST)Researchers have d

Updated on:June 08,2024 3

Researchers identify protein that controls CAR T cell longevity

byChildren's Hospital of PhiladelphiaLike a lightbulb, CAR T cells designed to kill cancer often burn out due to exhaustion and poor persistence. Doan et al. discovered that a transcription

Updated on: April 28,2024 0

Researchers identify protein that controls CAR T cell longevity

byChildren's Hospital of PhiladelphiaLike a lightbulb, CAR T cells designed to kill cancer often burn out due to exhaustion and poor persistence. Doan et al. discovered that a transcription

Updated on:April 28,2024 0

A new approach to targeting tumors and tracking their spread

by Massachusetts Institute of TechnologyKiller T cells surround a cancer cell. Credit: NIHThe spread of malignant cells from an original tumor to other parts of the body, known as metastasis, is

Updated on: May 20,2024 3

A new approach to targeting tumors and tracking their spread

by Massachusetts Institute of TechnologyKiller T cells surround a cancer cell. Credit: NIHThe spread of malignant cells from an original tumor to other parts of the body, known as metastasis, is

Updated on:May 20,2024 3

A liquid biopsy test can identify patients who may respond to immune checkpoint blockade

by American Association for Cancer ResearchCredit: CC0 Public DomainA new liquid biopsy test could detect microsatellite instability (MSI) and tumor mutational burden (TMB), indicating that it co

Updated on: May 23,2024 8

A liquid biopsy test can identify patients who may respond to immune checkpoint blockade

by American Association for Cancer ResearchCredit: CC0 Public DomainA new liquid biopsy test could detect microsatellite instability (MSI) and tumor mutational burden (TMB), indicating that it co

Updated on:May 23,2024 8

Tracking the epigenetic evolution of a cancer, cell by cell

by Weill Cornell Medical CollegeDr. Dan Landau. Credit: Rene PerezA powerful new set of scientific tools developed by Weill Cornell Medicine and New York Genome Center (NYGC) researchers enables

Updated on: May 23,2024 3

Tracking the epigenetic evolution of a cancer, cell by cell

by Weill Cornell Medical CollegeDr. Dan Landau. Credit: Rene PerezA powerful new set of scientific tools developed by Weill Cornell Medicine and New York Genome Center (NYGC) researchers enables

Updated on:May 23,2024 3