Researchers identify protein that controls CAR T cell longevity

byChildren's Hospital of PhiladelphiaLike a lightbulb, CAR T cells designed to kill cancer often burn out due to exhaustion and poor persistence. Doan et al. discovered that a transcription

Updated on: April 28,2024

Researchers identify protein that controls CAR T cell longevity

byChildren's Hospital of PhiladelphiaLike a lightbulb, CAR T cells designed to kill cancer often burn out due to exhaustion and poor persistence. Doan et al. discovered that a transcription

Updated on:April 28,2024

Tumor mutations may predict response to immunotherapy

by Johns Hopkins University School of MedicineMismatch repair deficiency refers to a characteristic of some cancer cells that create a large number of mutations, or changes, in certain genes when

Updated on: April 07,2024

Tumor mutations may predict response to immunotherapy

by Johns Hopkins University School of MedicineMismatch repair deficiency refers to a characteristic of some cancer cells that create a large number of mutations, or changes, in certain genes when

Updated on:April 07,2024

App an effective tool to record sun exposure

by Queensland University of TechnologyCredit: Queensland University of TechnologyA smartphone app is an accessible tool that reliably measures the amount of exposure to the sun's skin-damagin

Updated on: March 30,2024

App an effective tool to record sun exposure

by Queensland University of TechnologyCredit: Queensland University of TechnologyA smartphone app is an accessible tool that reliably measures the amount of exposure to the sun's skin-damagin

Updated on:March 30,2024

Incoming New Zealand govt to abandon anti-smoking laws

Credit: CC0 Public DomainNew Zealand's incoming conservative government will jettison world-leading measures to stub out smoking, new Prime Minister Christopher Luxon confirmed Monday, in a move d

Updated on: March 06,2024

Incoming New Zealand govt to abandon anti-smoking laws

Credit: CC0 Public DomainNew Zealand's incoming conservative government will jettison world-leading measures to stub out smoking, new Prime Minister Christopher Luxon confirmed Monday, in a move d

Updated on:March 06,2024

Study overturns dogma of cancer metabolism theory

by University of California, Los AngelesImage shows squamous cell skin cancer tumors with lactate production (a byproduct of glucose consumption) in purple. The tumor with lactate production bloc

Updated on: June 01,2024

Study overturns dogma of cancer metabolism theory

by University of California, Los AngelesImage shows squamous cell skin cancer tumors with lactate production (a byproduct of glucose consumption) in purple. The tumor with lactate production bloc

Updated on:June 01,2024

New blood test developed to diagnose ovarian cancer

by Brigham and Women's HospitalIntermediate magnification micrograph of a low malignant potential (LMP) mucinous ovarian tumour. H&E stain. The micrograph shows: Simple mucinous epitheliu

Updated on: April 14,2024

New blood test developed to diagnose ovarian cancer

by Brigham and Women's HospitalIntermediate magnification micrograph of a low malignant potential (LMP) mucinous ovarian tumour. H&E stain. The micrograph shows: Simple mucinous epitheliu

Updated on:April 14,2024

Study shows why a common form of immunotherapy fails, and suggests solution

by Georgetown University Medical CenterSamir N. Khleif, MD, director of The Loop Immuno-Oncology Laboratory at Georgetown Lombardi, led the research team that published new research on checkpoint

Updated on: March 01,2024

Study shows why a common form of immunotherapy fails, and suggests solution

by Georgetown University Medical CenterSamir N. Khleif, MD, director of The Loop Immuno-Oncology Laboratory at Georgetown Lombardi, led the research team that published new research on checkpoint

Updated on:March 01,2024

Study suggests possible way to 'Smac' cancer

by Dana-Farber Cancer InstituteCredit: Pixabay/CC0 Public DomainIn animals, a process of programmed cell death called apoptosis ensures cells die when they should. An opposing force, governed by

Updated on: January 30,2024

Study suggests possible way to 'Smac' cancer

by Dana-Farber Cancer InstituteCredit: Pixabay/CC0 Public DomainIn animals, a process of programmed cell death called apoptosis ensures cells die when they should. An opposing force, governed by

Updated on:January 30,2024

Subtyping of breast cancer cell lines reveals insights into cancer-relevant genes

by Manuela Schüngel, Leibniz-Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbHWaterfall plot depicting recurrent non-synonymous mutations in BC cell lines. Mutations were calle

Updated on: March 30,2024

Subtyping of breast cancer cell lines reveals insights into cancer-relevant genes

by Manuela Schüngel, Leibniz-Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbHWaterfall plot depicting recurrent non-synonymous mutations in BC cell lines. Mutations were calle

Updated on:March 30,2024

Research offers new approach to nongenetic T-cell-based immunotherapy

by WileyCredit: WileyImmunotherapies for cancer aim to induce the immune system to combat cancer cells more effectively. In the journalAngewandte Chemie International Edition, a Chinese res

Updated on: January 30,2024

Research offers new approach to nongenetic T-cell-based immunotherapy

by WileyCredit: WileyImmunotherapies for cancer aim to induce the immune system to combat cancer cells more effectively. In the journalAngewandte Chemie International Edition, a Chinese res

Updated on:January 30,2024

Taming overactive molecular signaling in renal cell cancer

by Johns Hopkins University School of MedicineMurine renal tumors with Tsc2 loss have increased TFEB/TFE3 nuclear localization. Credit: Clarence Rachel Villanueva and Adrianna A. Mendes,Nat

Updated on: February 01,2024

Taming overactive molecular signaling in renal cell cancer

by Johns Hopkins University School of MedicineMurine renal tumors with Tsc2 loss have increased TFEB/TFE3 nuclear localization. Credit: Clarence Rachel Villanueva and Adrianna A. Mendes,Nat

Updated on:February 01,2024

Potential therapeutic target for small cell lung cancer discovered

by Melissa Rohman,Northwestern UniversityGraphic model showing how POU2AF2 establishes the poised enhancer via SWI/SNF activity-dependent recruitment of the Polycomb complex in SCLC-P subtype ce

Updated on: April 28,2024

Potential therapeutic target for small cell lung cancer discovered

by Melissa Rohman,Northwestern UniversityGraphic model showing how POU2AF2 establishes the poised enhancer via SWI/SNF activity-dependent recruitment of the Polycomb complex in SCLC-P subtype ce

Updated on:April 28,2024