Why a promising breast cancer drug doesn't work—and how to improve it

by Katherine Fenz,Rockefeller UniversityER-mediated transcriptional resistance to BD inhibition. Credit:Nature Structural & Molecular Biology(2024). DOI: 10.1038/s41594-024-01384

Updated on: September 28,2024

Why a promising breast cancer drug doesn't work—and how to improve it

by Katherine Fenz,Rockefeller UniversityER-mediated transcriptional resistance to BD inhibition. Credit:Nature Structural & Molecular Biology(2024). DOI: 10.1038/s41594-024-01384

Updated on:September 28,2024

Drug resistance is a powerful menace in certain breast and ovarian cancers. Now scientists are figuring out why

by Delthia Ricks , Medical XpressCredit: Unsplash/CC0 Public DomainJust as bacteria, viruses and fungi develop strategies to outsmart antimicrobial medications, cancer cells can become resistant to ch

Updated on: February 18,2024

Drug resistance is a powerful menace in certain breast and ovarian cancers. Now scientists are figuring out why

by Delthia Ricks , Medical XpressCredit: Unsplash/CC0 Public DomainJust as bacteria, viruses and fungi develop strategies to outsmart antimicrobial medications, cancer cells can become resistant to ch

Updated on:February 18,2024

Researchers discover a mechanism that controls the identity of stem cells

by University of California, IrvineCredit:Molecular Cell(2023). DOI: 10.1016/j.molcel.2023.10.036Researchers at the University of California, Irvine, discovered a mechanism that contr

Updated on: February 03,2024

Researchers discover a mechanism that controls the identity of stem cells

by University of California, IrvineCredit:Molecular Cell(2023). DOI: 10.1016/j.molcel.2023.10.036Researchers at the University of California, Irvine, discovered a mechanism that contr

Updated on:February 03,2024

New screening tool to explore mechanisms behind cancer, autoimmunity and neurodegeneration

by Jelena Pupavac,Wellcome Trust Sanger InstituteA single-cell base editor screen tiling acrossJAK1is improved by coupling genotype with transcriptome.aUMAP of LoF and no

Updated on: April 23,2024

New screening tool to explore mechanisms behind cancer, autoimmunity and neurodegeneration

by Jelena Pupavac,Wellcome Trust Sanger InstituteA single-cell base editor screen tiling acrossJAK1is improved by coupling genotype with transcriptome.aUMAP of LoF and no

Updated on:April 23,2024

Seeking microscopic clues to beating deadly brain tumors

by Hackensack Meridian HealthH&E stained sections of patient glioblastoma samples. Higher magnifcation of representative regions are shown in the colored boxes. Histologic features include low (bl

Updated on: January 23,2024

Seeking microscopic clues to beating deadly brain tumors

by Hackensack Meridian HealthH&E stained sections of patient glioblastoma samples. Higher magnifcation of representative regions are shown in the colored boxes. Histologic features include low (bl

Updated on:January 23,2024

Researchers identify new gene mutation in familial thyroid cancers

by Pennsylvania State UniversityCredit: CC0 Public DomainResearchers from Penn State College of Medicine identified a new gene mutation that may cause a type of familial thyroid cancer. Dr. Darri

Updated on: June 04,2024

Researchers identify new gene mutation in familial thyroid cancers

by Pennsylvania State UniversityCredit: CC0 Public DomainResearchers from Penn State College of Medicine identified a new gene mutation that may cause a type of familial thyroid cancer. Dr. Darri

Updated on:June 04,2024

Simple test could lead to more personalized treatment of rare ovarian cancer

by University of New South WalesKaplan Meier curves of overall survival of ‘high’, ‘medium’ and ‘low’ tertiles of mRNA expression of THSB2 (left) and TAGLN (right) in MOC (n=185). Credit:Cl

Updated on: January 29,2024

Simple test could lead to more personalized treatment of rare ovarian cancer

by University of New South WalesKaplan Meier curves of overall survival of ‘high’, ‘medium’ and ‘low’ tertiles of mRNA expression of THSB2 (left) and TAGLN (right) in MOC (n=185). Credit:Cl

Updated on:January 29,2024

Decrease in breast cancer mortality rate continues. Wide gap for Black women remains stagnant

byAmerican Cancer SocietyCredit: Unsplash/CC0 Public DomainWhile breast cancer death rates dropped by 43% from 1989 to 2020, Black women continue to be 40% more likely to die from the disease de

Updated on: January 03,2024

Decrease in breast cancer mortality rate continues. Wide gap for Black women remains stagnant

byAmerican Cancer SocietyCredit: Unsplash/CC0 Public DomainWhile breast cancer death rates dropped by 43% from 1989 to 2020, Black women continue to be 40% more likely to die from the disease de

Updated on:January 03,2024

Researchers use AI to understand lung cancer cell vulnerabilities

by University of MontanaMark Grimes, a researcher and University of Montana biology professor, uses AI to learn more about lung cancer vulnerabilities. Credit: University of Montana photo by Tomm

Updated on: February 18,2024

Researchers use AI to understand lung cancer cell vulnerabilities

by University of MontanaMark Grimes, a researcher and University of Montana biology professor, uses AI to learn more about lung cancer vulnerabilities. Credit: University of Montana photo by Tomm

Updated on:February 18,2024

Study shows the benefit of harnessing the body's own immune cells to fight brain cancer

by Salk InstituteCredit: Human Brain ProjectGlioblastoma, the most common and deadly form of brain cancer, grows rapidly to invade and destroy healthy brain tissue. The tumor sends out cancerous

Updated on: February 24,2024

Study shows the benefit of harnessing the body's own immune cells to fight brain cancer

by Salk InstituteCredit: Human Brain ProjectGlioblastoma, the most common and deadly form of brain cancer, grows rapidly to invade and destroy healthy brain tissue. The tumor sends out cancerous

Updated on:February 24,2024

Researchers explore why patients don't follow up with their doctors after receiving a positive colorectal cancer test

by American Academy of Family PhysiciansReasons for no colonoscopy after an unfavorable screening result in Dutch colorectal cancer screening: a nation-wise questionnaire. Credit:The Annals

Updated on: February 01,2024

Researchers explore why patients don't follow up with their doctors after receiving a positive colorectal cancer test

by American Academy of Family PhysiciansReasons for no colonoscopy after an unfavorable screening result in Dutch colorectal cancer screening: a nation-wise questionnaire. Credit:The Annals

Updated on:February 01,2024

Drug compound could be next-generation treatment for aggressive form of leukemia

by Tom Coyne,Purdue UniversityHerman Sintim, the Drug Discovery Professor of Chemistry in Purdue University's Department of Chemistry, is leading a team of researchers developing a series of

Updated on: May 25,2024

Drug compound could be next-generation treatment for aggressive form of leukemia

by Tom Coyne,Purdue UniversityHerman Sintim, the Drug Discovery Professor of Chemistry in Purdue University's Department of Chemistry, is leading a team of researchers developing a series of

Updated on:May 25,2024