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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Cancer drug data release set to power next wave of therapeutic discovery

Cancer drug data release set to power next wave of therapeutic discovery

by Wellcome Sanger InstituteCredit: CC0 Public DomainThis week (25 July) the Genomics of Drug Sensitivity in Cancer project has released the results of four years of intense data gathering and explora

Cancer drug data release set to power next wave of therapeutic discovery

by Wellcome Sanger InstituteCredit: CC0 Public DomainThis week (25 July) the Genomics of Drug Sensitivity in Cancer project has released the results of four years of intense data gathering and explora
Researchers describe a molecular strategy that helps prevent tumour formation in mice

Researchers describe a molecular strategy that helps prevent tumour formation in mice

by The Spanish National Cancer Research CentreCredit: CNIOThe body's process for manufacturing fatty acids is regulated by the enzyme FASN. In normal cells, this is not a very active process—

Researchers describe a molecular strategy that helps prevent tumour formation in mice

by The Spanish National Cancer Research CentreCredit: CNIOThe body's process for manufacturing fatty acids is regulated by the enzyme FASN. In normal cells, this is not a very active process—
Editorial: GBP3-STING interaction in glioblastoma coordinates poor response to temozolomide

Editorial: GBP3-STING interaction in glioblastoma coordinates poor response to temozolomide

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainA new editorial paper was published inOncotarget, titled "GBP3-STING interaction in glioblastoma coordinates autophagy, anti-oxidative

Editorial: GBP3-STING interaction in glioblastoma coordinates poor response to temozolomide

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainA new editorial paper was published inOncotarget, titled "GBP3-STING interaction in glioblastoma coordinates autophagy, anti-oxidative
Study of immune 'neighborhoods' highlights macrophages as key players in invasive breast cancers

Study of immune 'neighborhoods' highlights macrophages as key players in invasive breast cancers

byUniversity of PittsburghCredit: Unsplash/CC0 Public DomainMost immunotherapies, which aim to boost T cell activity, work poorly in treating estrogen receptor-positive (ER+) breast cancer. Targ

Study of immune 'neighborhoods' highlights macrophages as key players in invasive breast cancers

byUniversity of PittsburghCredit: Unsplash/CC0 Public DomainMost immunotherapies, which aim to boost T cell activity, work poorly in treating estrogen receptor-positive (ER+) breast cancer. Targ
Boosting T cell 'memory' may result in longer-lasting and effective responses for patients

Boosting T cell 'memory' may result in longer-lasting and effective responses for patients

by University of Texas M. D. Anderson Cancer CenterScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDJust like pe

Boosting T cell 'memory' may result in longer-lasting and effective responses for patients

by University of Texas M. D. Anderson Cancer CenterScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDJust like pe
Targeted therapy better for repeat kidney cancer patients than FDA-approved counterpart

Targeted therapy better for repeat kidney cancer patients than FDA-approved counterpart

by City of HopeKiller T cells surround a cancer cell. Credit: NIHKidney cancer patients who had already tried two or three different treatments had improved chances of preventing cancer progression wi

Targeted therapy better for repeat kidney cancer patients than FDA-approved counterpart

by City of HopeKiller T cells surround a cancer cell. Credit: NIHKidney cancer patients who had already tried two or three different treatments had improved chances of preventing cancer progression wi
Study brings insight to kidney cancer with gene mutation

Study brings insight to kidney cancer with gene mutation

by Anna Megdell,University of MichiganCredit: Pixabay/CC0 Public DomainA new study from clinicians and researchers at the University of Michigan Rogel Cancer Center, U-M Department of Pathology

Study brings insight to kidney cancer with gene mutation

by Anna Megdell,University of MichiganCredit: Pixabay/CC0 Public DomainA new study from clinicians and researchers at the University of Michigan Rogel Cancer Center, U-M Department of Pathology
Investigating the immunoregulatory protein CD200 as a potentially lucrative yet elusive target for cancer therapy

Investigating the immunoregulatory protein CD200 as a potentially lucrative yet elusive target for cancer therapy

by Impact Journals LLCMultiple mechanisms underly the pro-tumorigenic role of CD200. Credit: 2023 Shao and Owens.A new research perspective titled "The immunoregulatory protein CD200 as a potenti

Investigating the immunoregulatory protein CD200 as a potentially lucrative yet elusive target for cancer therapy

by Impact Journals LLCMultiple mechanisms underly the pro-tumorigenic role of CD200. Credit: 2023 Shao and Owens.A new research perspective titled "The immunoregulatory protein CD200 as a potenti
Drug turns cancer gene into 'eat me' flag for immune system

Drug turns cancer gene into 'eat me' flag for immune system

by Robin Marks,University of California, San FranciscoMicroscopy of a lung tumor biopsy. Credit: Lin MaTumor cells are notoriously good at evading the human immune system; they put up physical w

Drug turns cancer gene into 'eat me' flag for immune system

by Robin Marks,University of California, San FranciscoMicroscopy of a lung tumor biopsy. Credit: Lin MaTumor cells are notoriously good at evading the human immune system; they put up physical w
Does marital status affect prognosis after breast cancer diagnosis?

Does marital status affect prognosis after breast cancer diagnosis?

by WileyCredit: CC0 Public DomainIn aCancer Medicinestudy of 298,434 patients diagnosed with breast cancer between 2004 and 2012, married patients had a better prognosis than patients

Does marital status affect prognosis after breast cancer diagnosis?

by WileyCredit: CC0 Public DomainIn aCancer Medicinestudy of 298,434 patients diagnosed with breast cancer between 2004 and 2012, married patients had a better prognosis than patients
Substance in the blood is found to increase as early as two years before diagnosis of pancreatic cancer

Substance in the blood is found to increase as early as two years before diagnosis of pancreatic cancer

by Ola Nilsson,Umea UniversitySeparating future PDAC cases from controls in pre-diagnostic and diagnostic samples with a cross-sectional analysis. Box plots of the individual marker concentratio

Substance in the blood is found to increase as early as two years before diagnosis of pancreatic cancer

by Ola Nilsson,Umea UniversitySeparating future PDAC cases from controls in pre-diagnostic and diagnostic samples with a cross-sectional analysis. Box plots of the individual marker concentratio
How colliding genetic processes drive aggressive cancers

How colliding genetic processes drive aggressive cancers

byUniversity of Chicago Medical CenterLoss of CDK12 promotes large TD formation. Credit:Nature Cancer(2024). DOI: 10.1038/s43018-024-00848-4Cancer researchers at the University of Ch

How colliding genetic processes drive aggressive cancers

byUniversity of Chicago Medical CenterLoss of CDK12 promotes large TD formation. Credit:Nature Cancer(2024). DOI: 10.1038/s43018-024-00848-4Cancer researchers at the University of Ch