Blocking key pathways is a way to defeat cancer stem cells

by RIKENCancer cell during cell division. Credit: National Institutes of HealthScientists from the RIKEN Center for Integrative Medical Sciences in Japan and international collaborators have foun

Updated on: April 01,2024

Blocking key pathways is a way to defeat cancer stem cells

by RIKENCancer cell during cell division. Credit: National Institutes of HealthScientists from the RIKEN Center for Integrative Medical Sciences in Japan and international collaborators have foun

Updated on:April 01,2024

Early trial results show benefits of FGFR inhibitors and PARP/ATR inhibitor combinations in multiple tumor types

byUniversity of Texas M. D. Anderson Cancer CenterCredit: Pixabay/CC0 Public DomainResearchers from The University of Texas MD Anderson Cancer Center presented promising findings from multiple c

Updated on: January 29,2024

Early trial results show benefits of FGFR inhibitors and PARP/ATR inhibitor combinations in multiple tumor types

byUniversity of Texas M. D. Anderson Cancer CenterCredit: Pixabay/CC0 Public DomainResearchers from The University of Texas MD Anderson Cancer Center presented promising findings from multiple c

Updated on:January 29,2024

Researchers identify feature of early stage colorectal cancer tumors that signals aggressiveness

by Cheryl Critchley,Monash UniversityOncogenic KRAS-driven MAPK signaling confers tolerance to epithelial TGFβ activation. a Representative H&E and Alk5 ISH of small intestinal tissue from V

Updated on: February 20,2024

Researchers identify feature of early stage colorectal cancer tumors that signals aggressiveness

by Cheryl Critchley,Monash UniversityOncogenic KRAS-driven MAPK signaling confers tolerance to epithelial TGFβ activation. a Representative H&E and Alk5 ISH of small intestinal tissue from V

Updated on:February 20,2024

Drug combination provides a one-two punch attack against colorectal cancer

by National Cancer InstituteOn the left,SN38, the active metabolite of irinotecan, traps TOP1 on DNA, forming TOP1 cleavage complexes that are degraded upon their formation, as seen by the

Updated on: January 29,2024

Drug combination provides a one-two punch attack against colorectal cancer

by National Cancer InstituteOn the left,SN38, the active metabolite of irinotecan, traps TOP1 on DNA, forming TOP1 cleavage complexes that are degraded upon their formation, as seen by the

Updated on:January 29,2024

Simple test could lead to more personalized treatment of rare ovarian cancer

by University of New South WalesKaplan Meier curves of overall survival of ‘high’, ‘medium’ and ‘low’ tertiles of mRNA expression of THSB2 (left) and TAGLN (right) in MOC (n=185). Credit:Cl

Updated on: January 29,2024

Simple test could lead to more personalized treatment of rare ovarian cancer

by University of New South WalesKaplan Meier curves of overall survival of ‘high’, ‘medium’ and ‘low’ tertiles of mRNA expression of THSB2 (left) and TAGLN (right) in MOC (n=185). Credit:Cl

Updated on:January 29,2024

Stopping a rare childhood cancer in its tracks

byCold Spring Harbor LaboratoryScientists discovered targeting a protein called ETV6 can turn Ewing sarcoma cancer cells back to normal-looking and -behaving connective tissue cells, as seen abo

Updated on: January 22,2024

Stopping a rare childhood cancer in its tracks

byCold Spring Harbor LaboratoryScientists discovered targeting a protein called ETV6 can turn Ewing sarcoma cancer cells back to normal-looking and -behaving connective tissue cells, as seen abo

Updated on:January 22,2024

ASCT may offer alternative for therapy for high-risk follicular lymphoma

(HealthDay)—Autologous stem cell transplantation (ASCT) may be an effective treatment option in high-risk, early therapy failure (ETF) follicular lymphoma (FL), prior to the use of rituximab, accordin

Updated on: March 30,2024

ASCT may offer alternative for therapy for high-risk follicular lymphoma

(HealthDay)—Autologous stem cell transplantation (ASCT) may be an effective treatment option in high-risk, early therapy failure (ETF) follicular lymphoma (FL), prior to the use of rituximab, accordin

Updated on:March 30,2024

New alveolar soft-part sarcoma chip can mimic the microenvironment during angiogenesis

by Kyoto UniversityAngiogenic microenvironment of alveolar soft-part sarcoma (ASPS) in a microfluidic chip. Credit: KyotoU/Ryuji YokokawaCancer, the second leading cause of death worldwide, is mo

Updated on: March 30,2024

New alveolar soft-part sarcoma chip can mimic the microenvironment during angiogenesis

by Kyoto UniversityAngiogenic microenvironment of alveolar soft-part sarcoma (ASPS) in a microfluidic chip. Credit: KyotoU/Ryuji YokokawaCancer, the second leading cause of death worldwide, is mo

Updated on:March 30,2024

Research team leads adaptive, efficient multi-arm phase 2 clinical trial for glioblastoma

by Dana-Farber Cancer InstituteGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0An innovative phase 2 clinical trial led by Dana-Farber Cancer Institute, in collaboration with 10 maj

Updated on: May 27,2024

Research team leads adaptive, efficient multi-arm phase 2 clinical trial for glioblastoma

by Dana-Farber Cancer InstituteGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0An innovative phase 2 clinical trial led by Dana-Farber Cancer Institute, in collaboration with 10 maj

Updated on:May 27,2024

The ways astronauts prep for spaceflight could benefit cancer patients, say researchers

by Cell PressNASA astronaut Reid Wiseman, Expedition 40 flight engineer, equipped with a bungee harness, exercises on the Combined Operational Load Bearing External Resistance Treadmill (COLBERT)

Updated on: June 06,2024

The ways astronauts prep for spaceflight could benefit cancer patients, say researchers

by Cell PressNASA astronaut Reid Wiseman, Expedition 40 flight engineer, equipped with a bungee harness, exercises on the Combined Operational Load Bearing External Resistance Treadmill (COLBERT)

Updated on:June 06,2024

Some cancer patients can find it hard to tell family and friends

by Kenya HunterThis combination of 2023 photos shows Kate, Princess of Wales, left, and U.S. Secretary of Defense Lloyd Austin. For some cancer patients, sharing the news can be a difficult decision.

Updated on: March 30,2024

Some cancer patients can find it hard to tell family and friends

by Kenya HunterThis combination of 2023 photos shows Kate, Princess of Wales, left, and U.S. Secretary of Defense Lloyd Austin. For some cancer patients, sharing the news can be a difficult decision.

Updated on:March 30,2024

Women with breast cancer shed pounds thanks to telephone-based weight loss program, clinical trial finds

by Dana-Farber Cancer InstituteCredit: Pixabay/CC0 Public DomainWomen with obesity when they are diagnosed with early breast cancer have a higher risk of recurrence or a second cancer compared to

Updated on: January 30,2024

Women with breast cancer shed pounds thanks to telephone-based weight loss program, clinical trial finds

by Dana-Farber Cancer InstituteCredit: Pixabay/CC0 Public DomainWomen with obesity when they are diagnosed with early breast cancer have a higher risk of recurrence or a second cancer compared to

Updated on:January 30,2024