Novel therapeutic targets discovered for triple-negative breast cancer

by Melissa Rohman,Northwestern UniversityThe signature of TRIM21low/CD73highis associated with unfavorable immune response. (A) Proteomic data from CPTAC identified that the expression of

Updated on: December 21,2023 13

Novel therapeutic targets discovered for triple-negative breast cancer

by Melissa Rohman,Northwestern UniversityThe signature of TRIM21low/CD73highis associated with unfavorable immune response. (A) Proteomic data from CPTAC identified that the expression of

Updated on:December 21,2023 13

FAM3C encapsulated in circulating tumor-derived extracellular vesicles promotes distant growth in lung cancers

byNational University of SingaporeTumor-derived EVs containing FAM3C trigger aggressiveness of lung carcinoma cells in vivo. (A) Tail vein injection of A549 lung carcinoma cells in mouse model a

Updated on: December 19,2023 6

FAM3C encapsulated in circulating tumor-derived extracellular vesicles promotes distant growth in lung cancers

byNational University of SingaporeTumor-derived EVs containing FAM3C trigger aggressiveness of lung carcinoma cells in vivo. (A) Tail vein injection of A549 lung carcinoma cells in mouse model a

Updated on:December 19,2023 6

New cell-based immunotherapy offered for melanoma

by Julia Evangelou Strait,Washington University School of Medicine in St. LouisCredit: Pixabay/CC0 Public DomainSiteman Cancer Center, based at Barnes-Jewish Hospital and Washington University S

Updated on: April 02,2024 19

New cell-based immunotherapy offered for melanoma

by Julia Evangelou Strait,Washington University School of Medicine in St. LouisCredit: Pixabay/CC0 Public DomainSiteman Cancer Center, based at Barnes-Jewish Hospital and Washington University S

Updated on:April 02,2024 19

Why don't T cells destroy solid tumors during immunotherapy?

byUniversity of North Carolina Health Care3-D image of a T cell experiencing cell stress: endoplasmic reticulum (green), mitochondria (purple). Credit: Elizabeth Hunt, UNC School of MedicineThe

Updated on: January 08,2024 10

Why don't T cells destroy solid tumors during immunotherapy?

byUniversity of North Carolina Health Care3-D image of a T cell experiencing cell stress: endoplasmic reticulum (green), mitochondria (purple). Credit: Elizabeth Hunt, UNC School of MedicineThe

Updated on:January 08,2024 10

Can the flu shot help fight cancer?

byRush University Medical CenterCredit: CC0 Public DomainChanging the microenvironment of tumors to increase the immune system's response to them has been the goal of countless research and

Updated on: December 20,2023 12

Can the flu shot help fight cancer?

byRush University Medical CenterCredit: CC0 Public DomainChanging the microenvironment of tumors to increase the immune system's response to them has been the goal of countless research and

Updated on:December 20,2023 12

UC San Diego Moores administers its first personalized cancer vaccine

by Paul Sisson, The San Diego Union-TribuneCredit: Min Yu (Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC),USC Norris Comprehensive Cancer CenterMore than 18 round

Updated on: December 18,2023 18

UC San Diego Moores administers its first personalized cancer vaccine

by Paul Sisson, The San Diego Union-TribuneCredit: Min Yu (Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC),USC Norris Comprehensive Cancer CenterMore than 18 round

Updated on:December 18,2023 18

AstraZeneca to Discontinue Moxetumomab Pasudotox in US for Hairy Cell Leukemia

January 13, 2023Chris RyanMoxetumomab pasudotox-tdfk will be permanently discontinued in the United States market for the treatment of relapsed/refractory hairy cell leukemia.Hairy Cell Leukemia (Kate

Updated on: October 15,2023 168

AstraZeneca to Discontinue Moxetumomab Pasudotox in US for Hairy Cell Leukemia

January 13, 2023Chris RyanMoxetumomab pasudotox-tdfk will be permanently discontinued in the United States market for the treatment of relapsed/refractory hairy cell leukemia.Hairy Cell Leukemia (Kate

Updated on:October 15,2023 168

Using machine learning to identify undiagnosable cancers

by Bendta Schroeder,Massachusetts Institute of Technology“Machine learning tools like this one could empower oncologists to choose more effective treatments and give more guidance to their patie

Updated on: January 04,2024 9

Using machine learning to identify undiagnosable cancers

by Bendta Schroeder,Massachusetts Institute of Technology“Machine learning tools like this one could empower oncologists to choose more effective treatments and give more guidance to their patie

Updated on:January 04,2024 9

Tracking genes to fight breast cancer

byLeiden UniversityMicroscope image of moving breast cancer cells leaving a track. Koedoot: "We switched of certain proteins and then looked to see if the pathways changed." Credit: Es

Updated on: December 20,2023 21

Tracking genes to fight breast cancer

byLeiden UniversityMicroscope image of moving breast cancer cells leaving a track. Koedoot: "We switched of certain proteins and then looked to see if the pathways changed." Credit: Es

Updated on:December 20,2023 21

Seeking leukemia's Achilles heel

byAmerican Society for Biochemistry and Molecular BiologyGraphical abstract. Credit:Molecular & Cellular Proteomics(2023). DOI: 10.1016/j.mcpro.2023.100503A team of researchers h

Updated on: December 17,2023 10

Seeking leukemia's Achilles heel

byAmerican Society for Biochemistry and Molecular BiologyGraphical abstract. Credit:Molecular & Cellular Proteomics(2023). DOI: 10.1016/j.mcpro.2023.100503A team of researchers h

Updated on:December 17,2023 10

Targeted drug tagrisso could be advance against lung cancer

Updated on: December 19,2023 8

Targeted drug tagrisso could be advance against lung cancer

Updated on:December 19,2023 8

Iflinatamab Deruxtecan Elicits Clinical Activity in SCLC

September 10, 2023Jonah FeldmanTreatment with the antibody-drug conjugate ifinatamab deruxtecan in heavily pretreated patients with small cell lung cancer led to promising efficacy and a manageable sa

Updated on: October 11,2023 205

Iflinatamab Deruxtecan Elicits Clinical Activity in SCLC

September 10, 2023Jonah FeldmanTreatment with the antibody-drug conjugate ifinatamab deruxtecan in heavily pretreated patients with small cell lung cancer led to promising efficacy and a manageable sa

Updated on:October 11,2023 205