Alternative glucose breakdown ensures the survival of cancer cells

byGerman Cancer Research CenterCredit: Pixabay/CC0 Public DomainA key enzyme in sugar metabolism is inactivated particularly easily and efficiently by oxidative stress. Scientists at the German

Updated on: January 07,2024

Alternative glucose breakdown ensures the survival of cancer cells

byGerman Cancer Research CenterCredit: Pixabay/CC0 Public DomainA key enzyme in sugar metabolism is inactivated particularly easily and efficiently by oxidative stress. Scientists at the German

Updated on:January 07,2024

Survival of children with acute lymphatic leukemia has increased to 94%, study finds

by Princess Máxima Center for Pediatric OncologyCredit: Unsplash/CC0 Public DomainThe five-year survival of all children with acute lymphatic leukemia (ALL) has continued to increase to 94%. This is e

Updated on: January 23,2024

Survival of children with acute lymphatic leukemia has increased to 94%, study finds

by Princess Máxima Center for Pediatric OncologyCredit: Unsplash/CC0 Public DomainThe five-year survival of all children with acute lymphatic leukemia (ALL) has continued to increase to 94%. This is e

Updated on:January 23,2024

For metastatic prostate cancer, immunotherapy may have unexpected potential

byColumbia University Irving Medical CenterCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.10.006Immunotherapy has been disappointing as a prostate cancer treatment, but a new Co

Updated on: January 26,2024

For metastatic prostate cancer, immunotherapy may have unexpected potential

byColumbia University Irving Medical CenterCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.10.006Immunotherapy has been disappointing as a prostate cancer treatment, but a new Co

Updated on:January 26,2024

Combining cholesterol-lowering statins with existing cancer drug shows potent effect against breast cancer subtype

by Katie Brace,Beth Israel Deaconess Medical CenterTN/ER-low PDOs are sensitive to combination AZD5363 and pitavastatin. A panel of breast cancer PDOs were treated with DMSO, 1 µM AZD5363, 5 µM

Updated on: August 26,2024

Combining cholesterol-lowering statins with existing cancer drug shows potent effect against breast cancer subtype

by Katie Brace,Beth Israel Deaconess Medical CenterTN/ER-low PDOs are sensitive to combination AZD5363 and pitavastatin. A panel of breast cancer PDOs were treated with DMSO, 1 µM AZD5363, 5 µM

Updated on:August 26,2024

First-in-human clinical trial of CAR T cell therapy with new binding mechanism shows promising early responses

by Perelman School of Medicine at the University of PennsylvaniaSafety and efficacy of a novel anti-CD19 chimeric antigen receptor T cell product targeting a membrane-proximal domain of CD19 with

Updated on: January 26,2024

First-in-human clinical trial of CAR T cell therapy with new binding mechanism shows promising early responses

by Perelman School of Medicine at the University of PennsylvaniaSafety and efficacy of a novel anti-CD19 chimeric antigen receptor T cell product targeting a membrane-proximal domain of CD19 with

Updated on:January 26,2024

Smoking is to blame for most of England's socioeconomic disparity in cancer incidence

byPublic Library of ScienceA sign indicating a smoke-free environment. Credit: Cristian Guerrero, Unsplash, CC0The majority of the socioeconomic disparity (or deprivation gap) in cancer incidenc

Updated on: January 10,2024

Smoking is to blame for most of England's socioeconomic disparity in cancer incidence

byPublic Library of ScienceA sign indicating a smoke-free environment. Credit: Cristian Guerrero, Unsplash, CC0The majority of the socioeconomic disparity (or deprivation gap) in cancer incidenc

Updated on:January 10,2024

Researchers reveal key to targeting dormant cancer cells

by Garvan Institute of Medical Research3D view of a growing cancer colony and a single dormant cancer cell attached to the inner lining of bone. Credit: Dr Michelle McDonaldAn international team

Updated on: June 11,2024

Researchers reveal key to targeting dormant cancer cells

by Garvan Institute of Medical Research3D view of a growing cancer colony and a single dormant cancer cell attached to the inner lining of bone. Credit: Dr Michelle McDonaldAn international team

Updated on:June 11,2024

CAR T cell therapy targeting HER2 antigen shows promise against advanced sarcoma in clinical trial

byBaylor College of MedicineCredit: Pixabay/CC0 Public DomainResearchers at Texas Children's Cancer Center and the Center for Cell and Gene Therapy at Baylor College of Medicine, Texas Child

Updated on: April 30,2024

CAR T cell therapy targeting HER2 antigen shows promise against advanced sarcoma in clinical trial

byBaylor College of MedicineCredit: Pixabay/CC0 Public DomainResearchers at Texas Children's Cancer Center and the Center for Cell and Gene Therapy at Baylor College of Medicine, Texas Child

Updated on:April 30,2024

Novel CAR T-cell therapy demonstrates efficacy and safety in preclinical models of HER2-positive solid tumors

byVall d'Hebron Institute of OncologyGeneration and characterization of p95HER2.CART cells. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-53265-7One-third of

Updated on: December 02,2024

Novel CAR T-cell therapy demonstrates efficacy and safety in preclinical models of HER2-positive solid tumors

byVall d'Hebron Institute of OncologyGeneration and characterization of p95HER2.CART cells. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-53265-7One-third of

Updated on:December 02,2024

Researchers develop new CRISPR-based tool for cancer diagnosis

by Leah Buletti,University of FloridaThe one-pot EXTRA-CRISPR miRNA assay. Credit:Nature Biomedical Engineering(2023). DOI: 10.1038/s41551-023-01033-1A team of University of Florida

Updated on: January 30,2024

Researchers develop new CRISPR-based tool for cancer diagnosis

by Leah Buletti,University of FloridaThe one-pot EXTRA-CRISPR miRNA assay. Credit:Nature Biomedical Engineering(2023). DOI: 10.1038/s41551-023-01033-1A team of University of Florida

Updated on:January 30,2024

Exploring the role of reactive oxygen species in cellular health and disease through HyPerion

Updated on: July 17,2024

Exploring the role of reactive oxygen species in cellular health and disease through HyPerion

Updated on:July 17,2024

New hope for kidney cancer treatment using existing drugs

byWellcome Trust Sanger InstituteCredit: Omer Bayraktar & Kenny RobertsThe most comprehensive study of kidney cancer at single-cell level has discovered a potential drug target to treat rena

Updated on: December 28,2023

New hope for kidney cancer treatment using existing drugs

byWellcome Trust Sanger InstituteCredit: Omer Bayraktar & Kenny RobertsThe most comprehensive study of kidney cancer at single-cell level has discovered a potential drug target to treat rena

Updated on:December 28,2023