Two genomic studies could yield more effective, less toxic immunotherapies

by Institut CurieTE-Exon splicing junctions can help differentiate tumors from healthy tissue. Credit: Verge Scientific Communications / Antonela Merlotti / Marianne Burbage / Benjamin SadaccaMnemo Th

Updated on: December 28,2023 10

Two genomic studies could yield more effective, less toxic immunotherapies

by Institut CurieTE-Exon splicing junctions can help differentiate tumors from healthy tissue. Credit: Verge Scientific Communications / Antonela Merlotti / Marianne Burbage / Benjamin SadaccaMnemo Th

Updated on:December 28,2023 10

Designing an emergency stop switch for immunotherapies

by Ecole Polytechnique Federale de LausanneA mollecule allows for 'switching off' the therapy when a cancer patient's life is in danger. Credit: EPFLImmunotherapy, unlike chemotherapy

Updated on: March 09,2024 19

Designing an emergency stop switch for immunotherapies

by Ecole Polytechnique Federale de LausanneA mollecule allows for 'switching off' the therapy when a cancer patient's life is in danger. Credit: EPFLImmunotherapy, unlike chemotherapy

Updated on:March 09,2024 19

AI facilitates breakthrough in sinonasal cancer diagnostics

byLudwig Maximilian University of MunichMethylation array for the determination of DNA modifications. Credit: Jurmeister et al.Although tumors in the nasal cavity and the paranasal sinus are con

Updated on: January 02,2024 9

AI facilitates breakthrough in sinonasal cancer diagnostics

byLudwig Maximilian University of MunichMethylation array for the determination of DNA modifications. Credit: Jurmeister et al.Although tumors in the nasal cavity and the paranasal sinus are con

Updated on:January 02,2024 9

Exploring the role of RNA modification in normal hematopoiesis and acute myeloid leukemia pathogenesis

by Cactus CommunicationsThe review sheds light on the role of post-transcriptional RNA modifications in normal hematopoietic development and acute myeloid leukemia, and highlights novel therapeutic ta

Updated on: April 28,2024 0

Exploring the role of RNA modification in normal hematopoiesis and acute myeloid leukemia pathogenesis

by Cactus CommunicationsThe review sheds light on the role of post-transcriptional RNA modifications in normal hematopoietic development and acute myeloid leukemia, and highlights novel therapeutic ta

Updated on:April 28,2024 0

Study: Risk of cancer remains high for women over 50 with genetic BRCA1 or BRCA2 mutation

by University of TorontoCredit: Pixabay/CC0 Public DomainAlthough genetic mutations in BRCA1 or BRCA2 are associated with a younger onset of breast and ovarian cancer, women with these genetic mu

Updated on: February 01,2024 20

Study: Risk of cancer remains high for women over 50 with genetic BRCA1 or BRCA2 mutation

by University of TorontoCredit: Pixabay/CC0 Public DomainAlthough genetic mutations in BRCA1 or BRCA2 are associated with a younger onset of breast and ovarian cancer, women with these genetic mu

Updated on:February 01,2024 20

Cancers in distant organs alter liver function, shows study

by Jim Schnabel,Cornell UniversityRemote primary tumors induce metabolic dysfunction in the liver. Credit:Nature(2023). DOI: 10.1038/s41586-023-06114-4Cancers often release molecules

Updated on: January 22,2024 12

Cancers in distant organs alter liver function, shows study

by Jim Schnabel,Cornell UniversityRemote primary tumors induce metabolic dysfunction in the liver. Credit:Nature(2023). DOI: 10.1038/s41586-023-06114-4Cancers often release molecules

Updated on:January 22,2024 12

Oncology therapy at the end-of-life: Have we missed the mark?

by Yale Cancer CenterCredit:JAMA Oncology(2022). DOI: 10.1001/jamaoncol.2022.4666Continued treatment for patients with cancer near end-of-life delays conversations about goals of care and

Updated on: January 04,2024 9

Oncology therapy at the end-of-life: Have we missed the mark?

by Yale Cancer CenterCredit:JAMA Oncology(2022). DOI: 10.1001/jamaoncol.2022.4666Continued treatment for patients with cancer near end-of-life delays conversations about goals of care and

Updated on:January 04,2024 9

Cancer of the appendix: Very rare, but genes may play role

by Cara MurezWhile appendix cancer is rare, for a small percentage of patients the disease may be linked to a particular genetic variant, a new study suggests.Researchers built on earlier research wit

Updated on: December 28,2023 10

Cancer of the appendix: Very rare, but genes may play role

by Cara MurezWhile appendix cancer is rare, for a small percentage of patients the disease may be linked to a particular genetic variant, a new study suggests.Researchers built on earlier research wit

Updated on:December 28,2023 10

Study shows many expensive cancer drugs have unclear patient benefit

byUniversity of GothenburgDiseases targeted in the included trials. Credit:Clinical Drug Investigation(2023). DOI: 10.1007/s40261-023-01285-4New cancer drugs are being launched rapid

Updated on: January 16,2024 14

Study shows many expensive cancer drugs have unclear patient benefit

byUniversity of GothenburgDiseases targeted in the included trials. Credit:Clinical Drug Investigation(2023). DOI: 10.1007/s40261-023-01285-4New cancer drugs are being launched rapid

Updated on:January 16,2024 14

Unique insights into differences between primary and metastatic cancer by large-scale DNA data analyses

by Hartwig Medical FoundationInference of HLA-I tumor status with LILAC. a, Representation of the six immune escape pathways considered in the present study alongside their associated genes (adapted f

Updated on: January 07,2024 15

Unique insights into differences between primary and metastatic cancer by large-scale DNA data analyses

by Hartwig Medical FoundationInference of HLA-I tumor status with LILAC. a, Representation of the six immune escape pathways considered in the present study alongside their associated genes (adapted f

Updated on:January 07,2024 15

New study helps explain the anti-cancer properties of mannose sugar

bySanford Burnham Prebys Medical Discovery InstituteProposed model for the mechanism underlying anticancer activity of mannose in mannose phosphate isomerase knockout (MPI-KO) human cancer cells

Updated on: January 13,2024 16

New study helps explain the anti-cancer properties of mannose sugar

bySanford Burnham Prebys Medical Discovery InstituteProposed model for the mechanism underlying anticancer activity of mannose in mannose phosphate isomerase knockout (MPI-KO) human cancer cells

Updated on:January 13,2024 16

Researchers find Boswellia, an extract of frankincense, shows anti-cancer activity in small trial

JANUARY 11, 2024by Leslie Cantu,Medical University of South CarolinaMajor types of boswellic acids in B. serrate. Credit:Breast Cancer Research and Treatment(2024). DOI: 10.1007/s105

Updated on: March 28,2024 5

Researchers find Boswellia, an extract of frankincense, shows anti-cancer activity in small trial

JANUARY 11, 2024by Leslie Cantu,Medical University of South CarolinaMajor types of boswellic acids in B. serrate. Credit:Breast Cancer Research and Treatment(2024). DOI: 10.1007/s105

Updated on:March 28,2024 5