Researchers report encouraging immunotherapy option for relapsed myeloma patients

by The Mount Sinai HospitalTreatment breakdown of the multiple myeloma patient cohort. (A) Flow chart showing that the initial retrospective query yielded 115 RRMM patients enrolled on a BiAb cli

Updated on: February 18,2024 14

Researchers report encouraging immunotherapy option for relapsed myeloma patients

by The Mount Sinai HospitalTreatment breakdown of the multiple myeloma patient cohort. (A) Flow chart showing that the initial retrospective query yielded 115 RRMM patients enrolled on a BiAb cli

Updated on:February 18,2024 14

Combination drug activates calcium channels to trigger deadly influx of calcium ions inside tumor cells

JANUARY 29, 2024byWileyCredit:Angewandte Chemie International Edition(2024). DOI: 10.1002/anie.202317578Calcium ions are essential for cells, but can be toxic in higher concentration

Updated on: March 25,2024 6

Combination drug activates calcium channels to trigger deadly influx of calcium ions inside tumor cells

JANUARY 29, 2024byWileyCredit:Angewandte Chemie International Edition(2024). DOI: 10.1002/anie.202317578Calcium ions are essential for cells, but can be toxic in higher concentration

Updated on:March 25,2024 6

Early clinical trial data show gene therapy reversing sickle cell anemia

by Cincinnati Children's Hospital Medical CenterTechnicians work in the ISO-certified cleanroom laboratory at Cincinnati Children's, where gene-correction therapies are tested and produce

Updated on: April 20,2024 17

Early clinical trial data show gene therapy reversing sickle cell anemia

by Cincinnati Children's Hospital Medical CenterTechnicians work in the ISO-certified cleanroom laboratory at Cincinnati Children's, where gene-correction therapies are tested and produce

Updated on:April 20,2024 17

Researchers make major advance with cancer-killing antibody-drug conjugates

by Doug Bennett,University of FloridaCredit:Journal of Medicinal Chemistry(2023). DOI: 10.1021/acs.jmedchem.2c01771Building a new precision cancer treatment comes with no shortage of

Updated on: February 20,2024 18

Researchers make major advance with cancer-killing antibody-drug conjugates

by Doug Bennett,University of FloridaCredit:Journal of Medicinal Chemistry(2023). DOI: 10.1021/acs.jmedchem.2c01771Building a new precision cancer treatment comes with no shortage of

Updated on:February 20,2024 18

Syrian refugees are diagnosed with breast cancer younger and with more advanced tumors, study finds

byBrigham and Women’s HospitalCredit: Unsplash/CC0 Public DomainBrigham researchers and international collaborators identified the association with younger age and advanced stage at diagnosis, c

Updated on: January 23,2024 20

Syrian refugees are diagnosed with breast cancer younger and with more advanced tumors, study finds

byBrigham and Women’s HospitalCredit: Unsplash/CC0 Public DomainBrigham researchers and international collaborators identified the association with younger age and advanced stage at diagnosis, c

Updated on:January 23,2024 20

Changes in RECIST tumor measures correlate linearly with survival in patients treated with checkpoint inhibitors

by SWOG Cancer Research NetworkCredit: Pixabay/CC0 Public DomainThe Response Evaluation Criteria In Solid Tumors (RECIST), used in many clinical trials to evaluate changes in tumor burden over time, c

Updated on: January 28,2024 10

Changes in RECIST tumor measures correlate linearly with survival in patients treated with checkpoint inhibitors

by SWOG Cancer Research NetworkCredit: Pixabay/CC0 Public DomainThe Response Evaluation Criteria In Solid Tumors (RECIST), used in many clinical trials to evaluate changes in tumor burden over time, c

Updated on:January 28,2024 10

Study shows promising results for immunotherapy targeting skin cancer

by King's College LondonCSPG4 expression in malignant melanoma and normal tissues.aCSPG4 mRNA expression, derived from RNAseq data, across cell lines of different cancer cell type

Updated on: February 20,2024 16

Study shows promising results for immunotherapy targeting skin cancer

by King's College LondonCSPG4 expression in malignant melanoma and normal tissues.aCSPG4 mRNA expression, derived from RNAseq data, across cell lines of different cancer cell type

Updated on:February 20,2024 16

Addition of metastasis-directed therapy increases PFS in prostate cancer

by Elana GotkineThe addition of metastasis-directed therapy (MDT), consisting of definitive radiation therapy to all sites of disease, to hormone therapy results in improved progression-free survival

Updated on: January 21,2024 10

Addition of metastasis-directed therapy increases PFS in prostate cancer

by Elana GotkineThe addition of metastasis-directed therapy (MDT), consisting of definitive radiation therapy to all sites of disease, to hormone therapy results in improved progression-free survival

Updated on:January 21,2024 10

New CAR T-cell therapy research shows potential in solid tumors

by Peter MacCallum Cancer CenterCredit: Peter MacCallum Cancer CenterPeter Mac researchers have developed a new approach to chimeric antigen receptor (CAR) T-cell therapy which has proven effective in

Updated on: January 11,2024 12

New CAR T-cell therapy research shows potential in solid tumors

by Peter MacCallum Cancer CenterCredit: Peter MacCallum Cancer CenterPeter Mac researchers have developed a new approach to chimeric antigen receptor (CAR) T-cell therapy which has proven effective in

Updated on:January 11,2024 12

Maximizing the potential of 3D-patient tumor avatars for next-generation precision oncology

by Terasaki Institute for Biomedical Innovation3D Patient Tumor Avatars (3D-PTAs) are part of a proposed integrative platform to provide optimal treatment selections for cancer patients. Such a platfo

Updated on: January 21,2024 19

Maximizing the potential of 3D-patient tumor avatars for next-generation precision oncology

by Terasaki Institute for Biomedical Innovation3D Patient Tumor Avatars (3D-PTAs) are part of a proposed integrative platform to provide optimal treatment selections for cancer patients. Such a platfo

Updated on:January 21,2024 19

Ethnic diversity and disparities in access to genetic testing impact prostate cancer development and treatment

byEuropean Society for Medical OncologyCredit: Unsplash/CC0 Public DomainMore than 1.4 million men were diagnosed with prostate cancer in 2020 globally, but the molecular characteristics of the

Updated on: January 22,2024 10

Ethnic diversity and disparities in access to genetic testing impact prostate cancer development and treatment

byEuropean Society for Medical OncologyCredit: Unsplash/CC0 Public DomainMore than 1.4 million men were diagnosed with prostate cancer in 2020 globally, but the molecular characteristics of the

Updated on:January 22,2024 10

Treatment decisions in new era of individualized therapy for metastatic hormone-sensitive prostate cancer

byDana-Farber Cancer InstituteProstate cancer cells. Credit: NIH Image GalleryOncologists have traditionally prescribed androgen deprivation therapy (ADT) alone for patients with metastatic horm

Updated on: January 22,2024 13

Treatment decisions in new era of individualized therapy for metastatic hormone-sensitive prostate cancer

byDana-Farber Cancer InstituteProstate cancer cells. Credit: NIH Image GalleryOncologists have traditionally prescribed androgen deprivation therapy (ADT) alone for patients with metastatic horm

Updated on:January 22,2024 13