Oncology therapy at the end-of-life: Have we missed the mark?

by Yale Cancer CenterCredit:JAMA Oncology(2022). DOI: 10.1001/jamaoncol.2022.4666Continued treatment for patients with cancer near end-of-life delays conversations about goals of care and

Updated on: January 04,2024

Oncology therapy at the end-of-life: Have we missed the mark?

by Yale Cancer CenterCredit:JAMA Oncology(2022). DOI: 10.1001/jamaoncol.2022.4666Continued treatment for patients with cancer near end-of-life delays conversations about goals of care and

Updated on:January 04,2024

Map of tumors' immune cell populations points to new targets for immunotherapy

by Kevin Jiang,Harvard Medical SchoolMyeloid immune cells alongsidered blood cells in an electron micrograph of human blood. Credit: National Cancer InstituteThe recent emergence of immuno

Updated on: April 09,2024

Map of tumors' immune cell populations points to new targets for immunotherapy

by Kevin Jiang,Harvard Medical SchoolMyeloid immune cells alongsidered blood cells in an electron micrograph of human blood. Credit: National Cancer InstituteThe recent emergence of immuno

Updated on:April 09,2024

Encyclopedic tumor analysis for guiding treatment of advanced, broadly refractory cancers

by OncotargetCONSORT diagram. Credit: Ajay SrinivasanRESILIENT was a single arm, open label, phase II/III study to test if label agnostic therapy regimens guided by Encyclopedic Tumor Analysis can off

Updated on: May 09,2024

Encyclopedic tumor analysis for guiding treatment of advanced, broadly refractory cancers

by OncotargetCONSORT diagram. Credit: Ajay SrinivasanRESILIENT was a single arm, open label, phase II/III study to test if label agnostic therapy regimens guided by Encyclopedic Tumor Analysis can off

Updated on:May 09,2024

Brown fat may help improve cancer survival rates

byAmerican Physiological SocietyBrown fat status is not associated with survival in patients with cancer-associated cachexia. Forest plot of the adjusted hazard ratio of brown fat predicting mor

Updated on: January 21,2024

Brown fat may help improve cancer survival rates

byAmerican Physiological SocietyBrown fat status is not associated with survival in patients with cancer-associated cachexia. Forest plot of the adjusted hazard ratio of brown fat predicting mor

Updated on:January 21,2024

Just bad luck? Australian cancer patients nominate 'fate' as third most likely cause

by University of South AustraliaCredit: CC0 Public DomainWhat role does fate play when it comes to the 145,000 people diagnosed with cancer each year in Australia?Smoking, sun exposure,poor

Updated on: April 10,2024

Just bad luck? Australian cancer patients nominate 'fate' as third most likely cause

by University of South AustraliaCredit: CC0 Public DomainWhat role does fate play when it comes to the 145,000 people diagnosed with cancer each year in Australia?Smoking, sun exposure,poor

Updated on:April 10,2024

New study supports annual breast cancer screening for women over 40

by Asher Jones and Cynthia Patton,University of Pittsburgh Schools of the Health SciencesCredit: Pixabay/CC0 Public DomainWomen diagnosed with breast cancer who had regular screening mammograms

Updated on: September 07,2024

New study supports annual breast cancer screening for women over 40

by Asher Jones and Cynthia Patton,University of Pittsburgh Schools of the Health SciencesCredit: Pixabay/CC0 Public DomainWomen diagnosed with breast cancer who had regular screening mammograms

Updated on:September 07,2024

Immunotherapy targeting cancer fusion protein may hold key to treating rare liver cancer

by St. Jude Children's Research HospitalCredit: Unsplash/CC0 Public DomainFibrolamellar carcinoma (FLC) is a rare liver cancer with a poor prognosis if not addressed early with surgery. The d

Updated on: March 30,2024

Immunotherapy targeting cancer fusion protein may hold key to treating rare liver cancer

by St. Jude Children's Research HospitalCredit: Unsplash/CC0 Public DomainFibrolamellar carcinoma (FLC) is a rare liver cancer with a poor prognosis if not addressed early with surgery. The d

Updated on:March 30,2024

Investigating mechanisms of aggressive glioblastoma tumor growth

by Olivia Dimmer,Northwestern UniversitySchematic representation of the role of the LDHA–ERK–STAT3/YAP pathway in regulation of CCL2 and CCL7 in glioblastoma cells, which, in turn, promotes macr

Updated on: March 30,2024

Investigating mechanisms of aggressive glioblastoma tumor growth

by Olivia Dimmer,Northwestern UniversitySchematic representation of the role of the LDHA–ERK–STAT3/YAP pathway in regulation of CCL2 and CCL7 in glioblastoma cells, which, in turn, promotes macr

Updated on:March 30,2024

Study supports germline testing for all metastatic breast cancer patients

by Tom Wilemon,Vanderbilt University Medical CenterThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image c

Updated on: May 25,2024

Study supports germline testing for all metastatic breast cancer patients

by Tom Wilemon,Vanderbilt University Medical CenterThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image c

Updated on:May 25,2024

Artificial intelligence analysis of DNA fragmentomes and protein biomarkers noninvasively detects ovarian cancer

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainA blood-based machine learning assay that combines cell-free DNA (cfDNA) fragment patterns and levels of the proteins

Updated on: April 30,2024

Artificial intelligence analysis of DNA fragmentomes and protein biomarkers noninvasively detects ovarian cancer

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainA blood-based machine learning assay that combines cell-free DNA (cfDNA) fragment patterns and levels of the proteins

Updated on:April 30,2024

Study provides new look at why rare cancer often evades treatments

by Boston Medical CenterCharacterizing the cellular landscape of pancreatic, small intestinal, and gNETs. (A) NET scRNA-seq workflow. Resected tumor fragments were dissociated into single-cell su

Updated on: February 03,2024

Study provides new look at why rare cancer often evades treatments

by Boston Medical CenterCharacterizing the cellular landscape of pancreatic, small intestinal, and gNETs. (A) NET scRNA-seq workflow. Resected tumor fragments were dissociated into single-cell su

Updated on:February 03,2024

New study highlights rapid adoption of clinical research results into chemotherapy prescribing patterns

by National Comprehensive Cancer NetworkCredit: Pixabay/CC0 Public DomainNew research inJNCCN—Journal of the National Comprehensive Cancer Networkevaluates how an important analysis on loc

Updated on: February 01,2024

New study highlights rapid adoption of clinical research results into chemotherapy prescribing patterns

by National Comprehensive Cancer NetworkCredit: Pixabay/CC0 Public DomainNew research inJNCCN—Journal of the National Comprehensive Cancer Networkevaluates how an important analysis on loc

Updated on:February 01,2024