Investigational personalized vaccine provides clinical benefit for some patients with resected head and neck cancers

byAmerican Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainTG4050, a personalized neoantigen vaccine, induced tumor-specific immune responses and led to low rates of disease rela

Updated on: April 28,2024

Investigational personalized vaccine provides clinical benefit for some patients with resected head and neck cancers

byAmerican Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainTG4050, a personalized neoantigen vaccine, induced tumor-specific immune responses and led to low rates of disease rela

Updated on:April 28,2024

Tumor microbiome linked to immunotherapy success in sarcoma patients

by Stephanie Winn,UC DavisSoft tissue sarcomas intratumoral microbiome at diagnosis may link with prognosis. (A) Representative gross examination of extremity synovial sarcoma specimen; asterisk

Updated on: January 22,2024

Tumor microbiome linked to immunotherapy success in sarcoma patients

by Stephanie Winn,UC DavisSoft tissue sarcomas intratumoral microbiome at diagnosis may link with prognosis. (A) Representative gross examination of extremity synovial sarcoma specimen; asterisk

Updated on:January 22,2024

Study sends strong signal not to sequence immune checkpoint inhibitors in advanced kidney cancer

byDana-Farber Cancer InstituteCredit: Pixabay/CC0 Public DomainPatients with advanced kidney cancer are routinely given immune checkpoint inhibitors (ICIs) as first-line treatment. The CONTACT-0

Updated on: January 22,2024

Study sends strong signal not to sequence immune checkpoint inhibitors in advanced kidney cancer

byDana-Farber Cancer InstituteCredit: Pixabay/CC0 Public DomainPatients with advanced kidney cancer are routinely given immune checkpoint inhibitors (ICIs) as first-line treatment. The CONTACT-0

Updated on:January 22,2024

New therapy proposed to treat 'axillary web syndrome' in women who have had a mastectomy

by University of MalagaNew therapy proposed to treat "axillary web syndrome" in women who have had a mastectomy. Credit: University of MalagaAxillary web syndrome, also known as lymphatic th

Updated on: January 15,2024

New therapy proposed to treat 'axillary web syndrome' in women who have had a mastectomy

by University of MalagaNew therapy proposed to treat "axillary web syndrome" in women who have had a mastectomy. Credit: University of MalagaAxillary web syndrome, also known as lymphatic th

Updated on:January 15,2024

New study unveils epigenetic 'traffic lights' controlling stop and go for gene activity

by Institute of Cancer ResearchAcute depletion of SET1/COMPASS core subunits reveals rapid turnover of H3K4me3.a, Schematic of the degron systems for the targeted degradation of DPY30 and R

Updated on: February 23,2024

New study unveils epigenetic 'traffic lights' controlling stop and go for gene activity

by Institute of Cancer ResearchAcute depletion of SET1/COMPASS core subunits reveals rapid turnover of H3K4me3.a, Schematic of the degron systems for the targeted degradation of DPY30 and R

Updated on:February 23,2024

Long-lasting radionuclide therapy for advanced neuroendocrine tumors proves effective

by Society of Nuclear Medicine and Molecular ImagingScans were done at 2, 24, 72, 120 and 168 hours after the administration of177Lu-DOTA-EB-TATE. The radiopharmaceutical cleared from the blood

Updated on: April 18,2024

Long-lasting radionuclide therapy for advanced neuroendocrine tumors proves effective

by Society of Nuclear Medicine and Molecular ImagingScans were done at 2, 24, 72, 120 and 168 hours after the administration of177Lu-DOTA-EB-TATE. The radiopharmaceutical cleared from the blood

Updated on:April 18,2024

Team uncovers promising lead in genetic approach to treating glioblastoma

by Anna C. Christensen,University of ArizonaBaldassarre Stea, MD, PhD, (center), treats brain tumors with DNA-damaging radiation. Credit: Anna C. ChristensenGlioblastoma, a deadly brain cancer t

Updated on: May 27,2024

Team uncovers promising lead in genetic approach to treating glioblastoma

by Anna C. Christensen,University of ArizonaBaldassarre Stea, MD, PhD, (center), treats brain tumors with DNA-damaging radiation. Credit: Anna C. ChristensenGlioblastoma, a deadly brain cancer t

Updated on:May 27,2024

A common genetic signature has been discovered among three cancer prone rare skin diseases

by Carlos III University of MadridGene expression signature in fibroblasts from RDEB, KS and XPC patients, compared to healthy donors (a). An alteration common to the three diseases of 227 genes

Updated on: April 22,2024

A common genetic signature has been discovered among three cancer prone rare skin diseases

by Carlos III University of MadridGene expression signature in fibroblasts from RDEB, KS and XPC patients, compared to healthy donors (a). An alteration common to the three diseases of 227 genes

Updated on:April 22,2024

Low-dose radiotherapy boost helps prevent local recurrence with better cosmetic outcomes in young breast cancer patients

by European Organisation for Research and Treatment of CancerThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Ima

Updated on: March 30,2024

Low-dose radiotherapy boost helps prevent local recurrence with better cosmetic outcomes in young breast cancer patients

by European Organisation for Research and Treatment of CancerThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Ima

Updated on:March 30,2024

New research shows how cancer rewires a key immune pathway to spread

byWeill Cornell Medical CollegeA collaboration between MSK and Weill Cornell Medicine used an approach called ContactTracing to predict the effect of interactions between cells in the tumor micr

Updated on: January 12,2024

New research shows how cancer rewires a key immune pathway to spread

byWeill Cornell Medical CollegeA collaboration between MSK and Weill Cornell Medicine used an approach called ContactTracing to predict the effect of interactions between cells in the tumor micr

Updated on:January 12,2024

Proteins in milk and blood could one day let doctors detect breast cancer earlier, and save lives

by Danielle Whitham,The ConversationCredit: Unsplash/CC0 Public DomainDoctors may someday be able to use bodily fluids to noninvasively detect breast cancer in patients earlier than is possible

Updated on: March 30,2024

Proteins in milk and blood could one day let doctors detect breast cancer earlier, and save lives

by Danielle Whitham,The ConversationCredit: Unsplash/CC0 Public DomainDoctors may someday be able to use bodily fluids to noninvasively detect breast cancer in patients earlier than is possible

Updated on:March 30,2024

Moles on the body largely influenced by genetics, finds new study

by King's College LondonMelanoma. Credit: Wikimedia Commons/National Cancer InstituteA study published this week in the journalPigment Cell & Melanoma Researchhas found that g

Updated on: May 21,2024

Moles on the body largely influenced by genetics, finds new study

by King's College LondonMelanoma. Credit: Wikimedia Commons/National Cancer InstituteA study published this week in the journalPigment Cell & Melanoma Researchhas found that g

Updated on:May 21,2024