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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
Sub Categories on Oncology
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Protein movement reveals brain tumor's weak spot

Protein movement reveals brain tumor's weak spot

by Annika Lund,Karolinska InstitutetCredit: Unsplash/CC0 Public DomainProteins do not have a single shape, but are more like dynamic robots. But—how do they actually move? And what does this tel

Protein movement reveals brain tumor's weak spot

by Annika Lund,Karolinska InstitutetCredit: Unsplash/CC0 Public DomainProteins do not have a single shape, but are more like dynamic robots. But—how do they actually move? And what does this tel
Camrelizumab Plus Nab-Paclitaxel Showcases Antitumor Activity in Platinum-Resistant Urothelial

Camrelizumab Plus Nab-Paclitaxel Showcases Antitumor Activity in Platinum-Resistant Urothelial

September 30, 2022Ryan ScottThe combination of camrelizumab and nab-paclitaxel produced encouraging responses in patients with platinum-resistant, unresectable locally advanced or metastatic urothelia

Camrelizumab Plus Nab-Paclitaxel Showcases Antitumor Activity in Platinum-Resistant Urothelial

September 30, 2022Ryan ScottThe combination of camrelizumab and nab-paclitaxel produced encouraging responses in patients with platinum-resistant, unresectable locally advanced or metastatic urothelia
Scientists discover metabolic feature that allows melanoma cells to spread

Scientists discover metabolic feature that allows melanoma cells to spread

by Katie Regan,UT Southwestern Medical CenterResearchers involved in the study include (from left) Drs. Brandon Faubert, Alpaslan Tasdogan, Sean Morrison, and Ralph DeBerardinis. Credit: UTSWRes

Scientists discover metabolic feature that allows melanoma cells to spread

by Katie Regan,UT Southwestern Medical CenterResearchers involved in the study include (from left) Drs. Brandon Faubert, Alpaslan Tasdogan, Sean Morrison, and Ralph DeBerardinis. Credit: UTSWRes
IBI322 Shows Early Antitumor Efficacy in PD-1/PD-L1–Resistant Classical Hodgkin Lymphoma

IBI322 Shows Early Antitumor Efficacy in PD-1/PD-L1–Resistant Classical Hodgkin Lymphoma

August 13, 2023Kristi RosaSingle-agent IBI322 elicited responses with favorable safety in patients with classical Hodgkin lymphoma that had become resistant to anti–PD-1/PD-L1 therapy, according to da

IBI322 Shows Early Antitumor Efficacy in PD-1/PD-L1–Resistant Classical Hodgkin Lymphoma

August 13, 2023Kristi RosaSingle-agent IBI322 elicited responses with favorable safety in patients with classical Hodgkin lymphoma that had become resistant to anti–PD-1/PD-L1 therapy, according to da
Pathogenesis to management of hepatocellular carcinoma

Pathogenesis to management of hepatocellular carcinoma

by Impact JournalsMolecular pathways and targeted therapeutics in hepatocellular carcinoma. Abbreviations: APC: antigen presenting cell; AXL is a cell surface receptor tyrosine kinase, part of the TAM

Pathogenesis to management of hepatocellular carcinoma

by Impact JournalsMolecular pathways and targeted therapeutics in hepatocellular carcinoma. Abbreviations: APC: antigen presenting cell; AXL is a cell surface receptor tyrosine kinase, part of the TAM
Faster genomics-based diagnosis may accelerate targeted treatment of patients with myeloid neoplasms

Faster genomics-based diagnosis may accelerate targeted treatment of patients with myeloid neoplasms

byElsevierA: Comparison of clinical assay variant allele fraction (VAF) and Ion Torrent Genexus VAF showed high correlation (r2= 0.98) across a broad range of VAFs, including both in-house

Faster genomics-based diagnosis may accelerate targeted treatment of patients with myeloid neoplasms

byElsevierA: Comparison of clinical assay variant allele fraction (VAF) and Ion Torrent Genexus VAF showed high correlation (r2= 0.98) across a broad range of VAFs, including both in-house
HDAC6 score found to predict the response of some cancers to ricolinostat

HDAC6 score found to predict the response of some cancers to ricolinostat

by Bob Yirka , Medical XpressHDAC6 score in BC. (a) The number of samples and dataset of origin used to evaluate the HDAC6 regulon. (b) Overlap of the original and updated HDAC6 regulons. P value was

HDAC6 score found to predict the response of some cancers to ricolinostat

by Bob Yirka , Medical XpressHDAC6 score in BC. (a) The number of samples and dataset of origin used to evaluate the HDAC6 regulon. (b) Overlap of the original and updated HDAC6 regulons. P value was
Online educational videos boost cancer knowledge

Online educational videos boost cancer knowledge

byRutgers UniversityCredit: CC0 Public DomainOnline health videos can be an important source of cancer education, according to Rutgers researchers. Their review, published in theJournal of

Online educational videos boost cancer knowledge

byRutgers UniversityCredit: CC0 Public DomainOnline health videos can be an important source of cancer education, according to Rutgers researchers. Their review, published in theJournal of
Overexpressed Cyclin D1 and CDK4 proteins are responsible for the resistance to CDK4/6 inhibitor in some breast cancer

Overexpressed Cyclin D1 and CDK4 proteins are responsible for the resistance to CDK4/6 inhibitor in some breast cancer

byScience China PressThe CDK4/6 inhibitors-resistant breast cancer cells expressed more Cyclin D1 and CDK4 proteins than the parental cells (Upper left). PI3K pathway was hyper-activated in the

Overexpressed Cyclin D1 and CDK4 proteins are responsible for the resistance to CDK4/6 inhibitor in some breast cancer

byScience China PressThe CDK4/6 inhibitors-resistant breast cancer cells expressed more Cyclin D1 and CDK4 proteins than the parental cells (Upper left). PI3K pathway was hyper-activated in the
Q&A: Genetic counseling after cancer diagnosis

Q&A: Genetic counseling after cancer diagnosis

by Breanna MitchellCredit: Unsplash/CC0 Public DomainI was diagnosed with ovarian cancer two months ago. My oncologist recommended that I undergo genetic testing as part of the treatment plan. Why is

Q&A: Genetic counseling after cancer diagnosis

by Breanna MitchellCredit: Unsplash/CC0 Public DomainI was diagnosed with ovarian cancer two months ago. My oncologist recommended that I undergo genetic testing as part of the treatment plan. Why is
Women with elevated breast cancer risk could see mortality benefit from estrogen-blocking drugs

Women with elevated breast cancer risk could see mortality benefit from estrogen-blocking drugs

byGeorgetown University Medical CenterCredit: Unsplash/CC0 Public DomainWhile it has long been recognized that drugs that block the cancer-promoting activity of estrogen reduce risk of developin

Women with elevated breast cancer risk could see mortality benefit from estrogen-blocking drugs

byGeorgetown University Medical CenterCredit: Unsplash/CC0 Public DomainWhile it has long been recognized that drugs that block the cancer-promoting activity of estrogen reduce risk of developin
hematopoietic changes on colon cancer, unveiling therapeutic avenues

hematopoietic changes on colon cancer, unveiling therapeutic avenues

In a recent study published in theJournal of Experimental Medicine, researchers investigated whether bone marrow-derived cells with heterozygous loss of Dnmt3a (Dnmt3a+/Δ), the most common genet

hematopoietic changes on colon cancer, unveiling therapeutic avenues

In a recent study published in theJournal of Experimental Medicine, researchers investigated whether bone marrow-derived cells with heterozygous loss of Dnmt3a (Dnmt3a+/Δ), the most common genet