Myths, ignorance persist around lung cancer: Poll

by Dennis ThompsonLung cancer is the leading cause of cancer deaths in the United States, but doctors have had access to a screening tool for nearly a decade that can catch it for early treatment.Unfo

Updated on: December 22,2023 15

Myths, ignorance persist around lung cancer: Poll

by Dennis ThompsonLung cancer is the leading cause of cancer deaths in the United States, but doctors have had access to a screening tool for nearly a decade that can catch it for early treatment.Unfo

Updated on:December 22,2023 15

AI-assisted breast-cancer screening may reduce unnecessary testing

byWashington University School of MedicineOn average, radiologists find one case of cancer (bottom images) in every 200 mammograms they evaluate. The top images show no cancer. In a recent study

Updated on: April 27,2024 0

AI-assisted breast-cancer screening may reduce unnecessary testing

byWashington University School of MedicineOn average, radiologists find one case of cancer (bottom images) in every 200 mammograms they evaluate. The top images show no cancer. In a recent study

Updated on:April 27,2024 0

Basic research opens up new therapeutic opportunities for fighting leukemia

byUniversity of Veterinary Medicine—ViennaGenome-wide CRISPR/Cas9-based loss-of-function screen identifies genetic dependencies of STAT3Y640F-driven cells a) Schematic illustration of a competit

Updated on: December 25,2023 11

Basic research opens up new therapeutic opportunities for fighting leukemia

byUniversity of Veterinary Medicine—ViennaGenome-wide CRISPR/Cas9-based loss-of-function screen identifies genetic dependencies of STAT3Y640F-driven cells a) Schematic illustration of a competit

Updated on:December 25,2023 11

Scientists reveal a potential new approach to treating liver cancer

byNational Institutes of Healtha, Schematic of drug screening and validation studies; MoA, mechanism of action.b, Graphs of the results from the small-molecule screen with the MIPE library

Updated on: December 27,2023 9

Scientists reveal a potential new approach to treating liver cancer

byNational Institutes of Healtha, Schematic of drug screening and validation studies; MoA, mechanism of action.b, Graphs of the results from the small-molecule screen with the MIPE library

Updated on:December 27,2023 9

Gut microbiome can play key role in response to CAR-T cell cancer immunotherapy

byGerman Cancer Research CenterCredit: Unsplash/CC0 Public DomainScientists from German Cancer Research Center (DKFZ), together with colleagues from Germany, Israel, and the U.S., have found tha

Updated on: December 19,2023 10

Gut microbiome can play key role in response to CAR-T cell cancer immunotherapy

byGerman Cancer Research CenterCredit: Unsplash/CC0 Public DomainScientists from German Cancer Research Center (DKFZ), together with colleagues from Germany, Israel, and the U.S., have found tha

Updated on:December 19,2023 10

AFM24 Plus Atezolizumab Shows Acceptable Safety, Early Activity in EGFR+ Solid Tumors

January 14, 2023Ryan ScottA doublet comprised of the bispecific innate cell engager AFM24 and atezolizumab had a tolerable safety profile and elicited responses in patients with advanced EGFR-expressi

Updated on: October 15,2023 163

AFM24 Plus Atezolizumab Shows Acceptable Safety, Early Activity in EGFR+ Solid Tumors

January 14, 2023Ryan ScottA doublet comprised of the bispecific innate cell engager AFM24 and atezolizumab had a tolerable safety profile and elicited responses in patients with advanced EGFR-expressi

Updated on:October 15,2023 163

Localizing BRCA gene mutations to better treat ovarian cancer

byUniversity of GenevaDistribution of mutations in BRCA1 and BRCA2. A. Graphical summary of BRCA1 and BRCA2 mutations. Mutation plot was generated using cBioPortal MutationMapper tool. Black = n

Updated on: December 20,2023 10

Localizing BRCA gene mutations to better treat ovarian cancer

byUniversity of GenevaDistribution of mutations in BRCA1 and BRCA2. A. Graphical summary of BRCA1 and BRCA2 mutations. Mutation plot was generated using cBioPortal MutationMapper tool. Black = n

Updated on:December 20,2023 10

Researchers elucidate roles of TP63 and SOX2 in squamous cell cancer progression

byNational University of SingaporeCredit: CC0 Public DomainSquamous cell carcinomas (SCCs) are aggressive malignancies arising from the squamous epithelium of various organs, such as the esophag

Updated on: December 18,2023 20

Researchers elucidate roles of TP63 and SOX2 in squamous cell cancer progression

byNational University of SingaporeCredit: CC0 Public DomainSquamous cell carcinomas (SCCs) are aggressive malignancies arising from the squamous epithelium of various organs, such as the esophag

Updated on:December 18,2023 20

First genomic study of puberty yields insights into development and cancer

by Huntsman Cancer InstituteBradley Cairns, Ph.D. Credit: Huntsman Cancer InstituteIn the first-ever genome-scale analysis of the puberty process in humans, researchers at Huntsman Cancer Institute (H

Updated on: December 20,2023 19

First genomic study of puberty yields insights into development and cancer

by Huntsman Cancer InstituteBradley Cairns, Ph.D. Credit: Huntsman Cancer InstituteIn the first-ever genome-scale analysis of the puberty process in humans, researchers at Huntsman Cancer Institute (H

Updated on:December 20,2023 19

MK256 is a novel CDK8 inhibitor with potent antitumor activity in AML through downregulation of the STAT pathway

by Impact Journals LLCEvaluation of the toxicity of MK256 in vivo. Credit:Oncotarget(2022). DOI: 10.18632/oncotarget.28305A new research paper titled "MK256 is a novel CDK8 inhibitor

Updated on: December 17,2023 10

MK256 is a novel CDK8 inhibitor with potent antitumor activity in AML through downregulation of the STAT pathway

by Impact Journals LLCEvaluation of the toxicity of MK256 in vivo. Credit:Oncotarget(2022). DOI: 10.18632/oncotarget.28305A new research paper titled "MK256 is a novel CDK8 inhibitor

Updated on:December 17,2023 10

Improving treatment for hairy cell leukemia

by Melissa Rohman,Northwestern UniversityCredit: Unsplash/CC0 Public DomainPatients with relapsed or refractory hairy cell leukemia who were treated with vemurafenib experienced excellent respon

Updated on: December 22,2023 8

Improving treatment for hairy cell leukemia

by Melissa Rohman,Northwestern UniversityCredit: Unsplash/CC0 Public DomainPatients with relapsed or refractory hairy cell leukemia who were treated with vemurafenib experienced excellent respon

Updated on:December 22,2023 8

Acute myeloid leukemia: Germany-wide clinical trial challenges international standard of care

by Nina Louis, Medizin & WissenschaftCredit:Blood(2022). DOI: 10.1182/blood-2022-159962Prior to allogeneic stem cell transplantation for the treatment of acute myeloid leukemia (AML),

Updated on: December 25,2023 15

Acute myeloid leukemia: Germany-wide clinical trial challenges international standard of care

by Nina Louis, Medizin & WissenschaftCredit:Blood(2022). DOI: 10.1182/blood-2022-159962Prior to allogeneic stem cell transplantation for the treatment of acute myeloid leukemia (AML),

Updated on:December 25,2023 15