New model explains how our immune system sometimes helps cancer spread

by Katie Willis,University of AlbertaCredit: CC0 Public DomainMathematicians at the University of Alberta have developed a model that explains how the immune system interacts with cancer—and in

Updated on: December 22,2023 12

New model explains how our immune system sometimes helps cancer spread

by Katie Willis,University of AlbertaCredit: CC0 Public DomainMathematicians at the University of Alberta have developed a model that explains how the immune system interacts with cancer—and in

Updated on:December 22,2023 12

Inhibition of prmt5 by repurposing market drugs: A fresh therapeutic pathway for cancer treatment

by TranSpreadDevelopment of AlphaLISA HTS screen to identify specific PRMT5 inhibitors. (A) Principle of AlphaLISA technique adapted to HTS. Biotinylated histone H4 (a well-known PRMT5 substrate) was

Updated on: January 04,2024 9

Inhibition of prmt5 by repurposing market drugs: A fresh therapeutic pathway for cancer treatment

by TranSpreadDevelopment of AlphaLISA HTS screen to identify specific PRMT5 inhibitors. (A) Principle of AlphaLISA technique adapted to HTS. Biotinylated histone H4 (a well-known PRMT5 substrate) was

Updated on:January 04,2024 9

New chemical technology leads to better targeted therapeutics against high-risk leukemia in lab

bySt. Jude Children's Research HospitalCredit: Unsplash/CC0 Public DomainMore-effective therapies are greatly needed for children with the high-risk blood cancer T-cell acute lymphoblastic l

Updated on: January 11,2024 15

New chemical technology leads to better targeted therapeutics against high-risk leukemia in lab

bySt. Jude Children's Research HospitalCredit: Unsplash/CC0 Public DomainMore-effective therapies are greatly needed for children with the high-risk blood cancer T-cell acute lymphoblastic l

Updated on:January 11,2024 15

Deaths from advanced lung cancer have dropped significantly since immunotherapy became standard-of-care

byWileyCredit: Unsplash/CC0 Public DomainSince the first immunotherapy drug to boost the body's immune response against advanced lung cancer was introduced in the United States in 2015, surv

Updated on: August 27,2024 0

Deaths from advanced lung cancer have dropped significantly since immunotherapy became standard-of-care

byWileyCredit: Unsplash/CC0 Public DomainSince the first immunotherapy drug to boost the body's immune response against advanced lung cancer was introduced in the United States in 2015, surv

Updated on:August 27,2024 0

Hyaluronan Degradation and TGF-β Signaling in extracellular matrix (ECM)-Mitochondria Communication

Updated on: September 21,2024 0

Hyaluronan Degradation and TGF-β Signaling in extracellular matrix (ECM)-Mitochondria Communication

Updated on:September 21,2024 0

Social determinants of health affect racial disparity in prostate cancer mortality

by Elana GotkineWhen accounting for social determinants of health (SDOH), Black men with prostate cancer have lower prostate cancer-specific mortality (PCSM) than White men, according to a systematic

Updated on: December 26,2023 6

Social determinants of health affect racial disparity in prostate cancer mortality

by Elana GotkineWhen accounting for social determinants of health (SDOH), Black men with prostate cancer have lower prostate cancer-specific mortality (PCSM) than White men, according to a systematic

Updated on:December 26,2023 6

New study seeks hereditary causes of childhood cancer

byKarolinska InstitutetOverview of study design and study cohort. Credit:The Lancet Regional Health—Europe(2024). DOI: 10.1016/j.lanepe.2024.100881Follow-up and treatment of children

Updated on: April 28,2024 0

New study seeks hereditary causes of childhood cancer

byKarolinska InstitutetOverview of study design and study cohort. Credit:The Lancet Regional Health—Europe(2024). DOI: 10.1016/j.lanepe.2024.100881Follow-up and treatment of children

Updated on:April 28,2024 0

Actin cytoskeleton remodeling protects tumor cells against immune attack

by Luxembourg Institute of HealthConfocal microscopy image. Accumulation of actin filaments (in green) at the immunological synapse of a resistant cancer cell in contact with an NK cell (in red). Cell

Updated on: December 18,2023 10

Actin cytoskeleton remodeling protects tumor cells against immune attack

by Luxembourg Institute of HealthConfocal microscopy image. Accumulation of actin filaments (in green) at the immunological synapse of a resistant cancer cell in contact with an NK cell (in red). Cell

Updated on:December 18,2023 10

Discovery unveils promising anticancer drug targeting KRAS protein

byVirginia Commonwealth UniversityKRB-456 inhibits the growth in vivo of orthotopic mt KRAS tumors derived from pancreatic cancer patients. Tumor biopsies from pancreatic cancer patient G160 wer

Updated on: December 30,2023 14

Discovery unveils promising anticancer drug targeting KRAS protein

byVirginia Commonwealth UniversityKRB-456 inhibits the growth in vivo of orthotopic mt KRAS tumors derived from pancreatic cancer patients. Tumor biopsies from pancreatic cancer patient G160 wer

Updated on:December 30,2023 14

New open-source software judges accuracy of computer predictions of cancer genetics

byThe Francis Crick InstituteCredit: CC0 Public DomainCancers are often made up of many cells which vary genetically to each other. These genetic differences mean the cancer may be particularly

Updated on: December 22,2023 21

New open-source software judges accuracy of computer predictions of cancer genetics

byThe Francis Crick InstituteCredit: CC0 Public DomainCancers are often made up of many cells which vary genetically to each other. These genetic differences mean the cancer may be particularly

Updated on:December 22,2023 21

Quantitative pathologic analysis may help predict prognosis in colorectal cancer

The quantitative segmentation algorithm (QuantCRC) may improve the prediction of prognosis in colorectal cancer (CRC), according to a study published online Aug. 16 inGastroenterology.Reetesh K.

Updated on: December 20,2023 13

Quantitative pathologic analysis may help predict prognosis in colorectal cancer

The quantitative segmentation algorithm (QuantCRC) may improve the prediction of prognosis in colorectal cancer (CRC), according to a study published online Aug. 16 inGastroenterology.Reetesh K.

Updated on:December 20,2023 13

'No one should cancel their colonoscopies': Addressing controversy from a recent clinical trial

by Leslie Orr,University of Rochester Medical CenterCredit: Unsplash/CC0 Public DomainDespite some confusing messages this week around the value of colonoscopies, Wilmot Cancer Institute physici

Updated on: December 28,2023 9

'No one should cancel their colonoscopies': Addressing controversy from a recent clinical trial

by Leslie Orr,University of Rochester Medical CenterCredit: Unsplash/CC0 Public DomainDespite some confusing messages this week around the value of colonoscopies, Wilmot Cancer Institute physici

Updated on:December 28,2023 9