Combining cholesterol-lowering statins with existing cancer drug shows potent effect against breast cancer subtype

by Katie Brace,Beth Israel Deaconess Medical CenterTN/ER-low PDOs are sensitive to combination AZD5363 and pitavastatin. A panel of breast cancer PDOs were treated with DMSO, 1 µM AZD5363, 5 µM

Updated on: August 26,2024

Combining cholesterol-lowering statins with existing cancer drug shows potent effect against breast cancer subtype

by Katie Brace,Beth Israel Deaconess Medical CenterTN/ER-low PDOs are sensitive to combination AZD5363 and pitavastatin. A panel of breast cancer PDOs were treated with DMSO, 1 µM AZD5363, 5 µM

Updated on:August 26,2024

Development and application of competing risks and multi-state models in cancer epidemiology

byKarolinska InstitutetCredit: Unsplash/CC0 Public DomainCompeting risks and multi-state models allow us to study complex disease settings and answer composite research questions and should be u

Updated on: December 18,2023

Development and application of competing risks and multi-state models in cancer epidemiology

byKarolinska InstitutetCredit: Unsplash/CC0 Public DomainCompeting risks and multi-state models allow us to study complex disease settings and answer composite research questions and should be u

Updated on:December 18,2023

New method for early detection of relapse in the blood cancer disease myelodysplastic syndrome

by Karolinska InstitutetCredit: CC0 Public DomainResearchers at the Department of Medicine, Huddinge (MedH), Magnus Tobiasson and Eva Hellström-Lindberg have, together with the Nordic MDS group,

Updated on: March 20,2024

New method for early detection of relapse in the blood cancer disease myelodysplastic syndrome

by Karolinska InstitutetCredit: CC0 Public DomainResearchers at the Department of Medicine, Huddinge (MedH), Magnus Tobiasson and Eva Hellström-Lindberg have, together with the Nordic MDS group,

Updated on:March 20,2024

Entering the golden age for antibody-drug conjugates in gynecologic cancer

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainIn an editorial, published inOncosciencetitled, "Entering the golden age for antibody-drug conjugates in gynecologic cancer,&quo

Updated on: July 17,2024

Entering the golden age for antibody-drug conjugates in gynecologic cancer

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainIn an editorial, published inOncosciencetitled, "Entering the golden age for antibody-drug conjugates in gynecologic cancer,&quo

Updated on:July 17,2024

A solid vaccine for liquid tumors

byHarvard UniversityCredit: CC0 Public DomainAcute myeloid leukemia (AML) is a deadly blood cancer that originates in the bone marrow and kills most of its victims within five years. Chemotherap

Updated on: December 20,2023

A solid vaccine for liquid tumors

byHarvard UniversityCredit: CC0 Public DomainAcute myeloid leukemia (AML) is a deadly blood cancer that originates in the bone marrow and kills most of its victims within five years. Chemotherap

Updated on:December 20,2023

Scientists to improve cancer treatment effectiveness

byNational Research Nuclear UniversityCredit: CC0 Public DomainTogether with researchers from the University of Nantes and the University of Reims Champagne-Ardenne in France, experts from the N

Updated on: December 18,2023

Scientists to improve cancer treatment effectiveness

byNational Research Nuclear UniversityCredit: CC0 Public DomainTogether with researchers from the University of Nantes and the University of Reims Champagne-Ardenne in France, experts from the N

Updated on:December 18,2023

Older US adults with certain preexisting conditions often diagnosed with poor prognosis cancers

byWileyCredit: Pixabay/CC0 Public DomainA recent analysis published in theJournal of the American Geriatrics Societyfound that before older U.S. adults were diagnosed with poor prognosis c

Updated on: December 25,2023

Older US adults with certain preexisting conditions often diagnosed with poor prognosis cancers

byWileyCredit: Pixabay/CC0 Public DomainA recent analysis published in theJournal of the American Geriatrics Societyfound that before older U.S. adults were diagnosed with poor prognosis c

Updated on:December 25,2023

Innovative test that detects complex DNA patterns may improve mesothelioma detection rate in blood

by Susan Murphy,Mayo ClinicStudy design. Our study involved detecting junctions that result from chromosomal rearrangements, insertions and deletions in mesothelioma in Step 1, then designing pr

Updated on: December 02,2024

Innovative test that detects complex DNA patterns may improve mesothelioma detection rate in blood

by Susan Murphy,Mayo ClinicStudy design. Our study involved detecting junctions that result from chromosomal rearrangements, insertions and deletions in mesothelioma in Step 1, then designing pr

Updated on:December 02,2024

UCLA researchers confirm mutations that predispose patients to rare kidney cancer syndrome

Researchers at the UCLA Jonsson Comprehensive Cancer Center have confirmed that a large number of genetic variants of unknown significance are in fact verified mutations that predispose patients to a

Updated on: November 19,2023

UCLA researchers confirm mutations that predispose patients to rare kidney cancer syndrome

Researchers at the UCLA Jonsson Comprehensive Cancer Center have confirmed that a large number of genetic variants of unknown significance are in fact verified mutations that predispose patients to a

Updated on:November 19,2023

The AI Blind Spot in Oncology: Why Oral Cancer Remains a Diagnostic Challenge

Oral cancer continues to exact a growing toll on global health, with incidence rates rising from 3.26 per 100,000 in 1990 to 5.34 in 2021.

Updated on: August 25,2025

The AI Blind Spot in Oncology: Why Oral Cancer Remains a Diagnostic Challenge

Oral cancer continues to exact a growing toll on global health, with incidence rates rising from 3.26 per 100,000 in 1990 to 5.34 in 2021.

Updated on:August 25,2025

Cancer stem cells use 'normal' genes in abnormal ways

by Garth Sundem,CU Anschutz Medical CampusMayumi Fajita, MD, PhD and colleagues show that CDK1 interacts with Sox2 to keep cancer stem cells 'stemmy'. Credit: University of Colorado Canc

Updated on: December 18,2023

Cancer stem cells use 'normal' genes in abnormal ways

by Garth Sundem,CU Anschutz Medical CampusMayumi Fajita, MD, PhD and colleagues show that CDK1 interacts with Sox2 to keep cancer stem cells 'stemmy'. Credit: University of Colorado Canc

Updated on:December 18,2023

Individuals with inflammatory breast cancer at higher risk of cancer spread to the brain

byWileyCredit: Unsplash/CC0 Public DomainNew research indicates that among individuals with breast cancer, those with a rare subtype called inflammatory breast cancer face a higher risk that the

Updated on: December 25,2023

Individuals with inflammatory breast cancer at higher risk of cancer spread to the brain

byWileyCredit: Unsplash/CC0 Public DomainNew research indicates that among individuals with breast cancer, those with a rare subtype called inflammatory breast cancer face a higher risk that the

Updated on:December 25,2023