New therapeutic strategy for chemotherapy resistance in ovarian cancer

byThe Wistar InstituteDr. Rugang Zhang. Credit: The Wistar InstituteA study from The Wistar Institute demonstrated that NAMPT, an enzyme critical for NAD+ biosynthesis, mediates selection of ste

Updated on: December 22,2023 23

New therapeutic strategy for chemotherapy resistance in ovarian cancer

byThe Wistar InstituteDr. Rugang Zhang. Credit: The Wistar InstituteA study from The Wistar Institute demonstrated that NAMPT, an enzyme critical for NAD+ biosynthesis, mediates selection of ste

Updated on:December 22,2023 23

Inhibition of prmt5 by repurposing market drugs: A fresh therapeutic pathway for cancer treatment

by TranSpreadDevelopment of AlphaLISA HTS screen to identify specific PRMT5 inhibitors. (A) Principle of AlphaLISA technique adapted to HTS. Biotinylated histone H4 (a well-known PRMT5 substrate) was

Updated on: January 04,2024 9

Inhibition of prmt5 by repurposing market drugs: A fresh therapeutic pathway for cancer treatment

by TranSpreadDevelopment of AlphaLISA HTS screen to identify specific PRMT5 inhibitors. (A) Principle of AlphaLISA technique adapted to HTS. Biotinylated histone H4 (a well-known PRMT5 substrate) was

Updated on:January 04,2024 9

Sleep disturbances are underappreciated in prostate cancer survivorship

by Tim Baker, Prostate Cancer Foundation of AustraliaCredit: CC0 Public DomainWe all got the memo that sleep is foundational for good health, right?Yet, it remains easy to overlook the importance of&n

Updated on: January 04,2024 13

Sleep disturbances are underappreciated in prostate cancer survivorship

by Tim Baker, Prostate Cancer Foundation of AustraliaCredit: CC0 Public DomainWe all got the memo that sleep is foundational for good health, right?Yet, it remains easy to overlook the importance of&n

Updated on:January 04,2024 13

Research suggests metabolite differences in young-onset versus average-onset colorectal cancer

byCleveland ClinicCancer—Histopathologic image of colonic carcinoid. Credit: Wikipedia/CC BY-SA 3.0New research from Cleveland Clinic supports the theory that environmental exposures—such as red

Updated on: January 22,2024 18

Research suggests metabolite differences in young-onset versus average-onset colorectal cancer

byCleveland ClinicCancer—Histopathologic image of colonic carcinoid. Credit: Wikipedia/CC BY-SA 3.0New research from Cleveland Clinic supports the theory that environmental exposures—such as red

Updated on:January 22,2024 18

Blood-based biomarker may redefine future treatment for advanced melanoma

byElsevierCirculating tumor DNA (ctDNA) correlates with radiology disease assessment and patient outcome. For patient A, biomarkers in their blood decreased over time and the radiology showed th

Updated on: January 05,2024 13

Blood-based biomarker may redefine future treatment for advanced melanoma

byElsevierCirculating tumor DNA (ctDNA) correlates with radiology disease assessment and patient outcome. For patient A, biomarkers in their blood decreased over time and the radiology showed th

Updated on:January 05,2024 13

Unfruitful: Eating more produce will not cure, stop prostate cancer

byUniversity of California - San DiegoMicrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia,CC BY-SA 3.0National guidelines recomme

Updated on: December 22,2023 19

Unfruitful: Eating more produce will not cure, stop prostate cancer

byUniversity of California - San DiegoMicrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia,CC BY-SA 3.0National guidelines recomme

Updated on:December 22,2023 19

Researchers find genetic variant contributing to disparities in childhood leukemia risk

by Keck School of Medicine of USCCredit: CC0 Public DomainAcute lymphoblastic leukemia (ALL), the most common childhood cancer, disproportionately affects children of Hispanic/Latino origin in th

Updated on: March 27,2024 0

Researchers find genetic variant contributing to disparities in childhood leukemia risk

by Keck School of Medicine of USCCredit: CC0 Public DomainAcute lymphoblastic leukemia (ALL), the most common childhood cancer, disproportionately affects children of Hispanic/Latino origin in th

Updated on:March 27,2024 0

Disorderly DNA helps cancer cells evade treatment

byNorthwestern UniversityWhen the chromatin packing is heterogenous and disordered, a cell demonstrates more plasticity. Credit: Northwestern UniversityEach cell in the human body holds a full t

Updated on: December 22,2023 10

Disorderly DNA helps cancer cells evade treatment

byNorthwestern UniversityWhen the chromatin packing is heterogenous and disordered, a cell demonstrates more plasticity. Credit: Northwestern UniversityEach cell in the human body holds a full t

Updated on:December 22,2023 10

Colonoscopy is the most comprehensive screening for colorectal cancer, despite flawed interpretations of a new study

by Franklin G. Berger,The ConversationCredit: American College of GastroenterologyA recently published study in a high-profile medical journal appeared to call into questionthe efficacy of

Updated on: December 26,2023 13

Colonoscopy is the most comprehensive screening for colorectal cancer, despite flawed interpretations of a new study

by Franklin G. Berger,The ConversationCredit: American College of GastroenterologyA recently published study in a high-profile medical journal appeared to call into questionthe efficacy of

Updated on:December 26,2023 13

Magnetic field patterns found to cause oncolysis via oxidative stress in glioma cells

by Thamarasee Jeewandara , Medical XpressCell culture stimulation setup, stimulation protocol and thermal imaging during sOMF stimulation to measure temperature changes. (A) Left—A schematic diagram o

Updated on: January 04,2024 7

Magnetic field patterns found to cause oncolysis via oxidative stress in glioma cells

by Thamarasee Jeewandara , Medical XpressCell culture stimulation setup, stimulation protocol and thermal imaging during sOMF stimulation to measure temperature changes. (A) Left—A schematic diagram o

Updated on:January 04,2024 7

Barriers to early clinical trial access for adolescents and young adults still exist

byEuropean Society for Medical OncologyYoung cancer patients at the crossroads of childhood and adulthood seem to be stuck in a treatment impasse. A study to be presented at the ESMO 2018 Congre

Updated on: December 18,2023 14

Barriers to early clinical trial access for adolescents and young adults still exist

byEuropean Society for Medical OncologyYoung cancer patients at the crossroads of childhood and adulthood seem to be stuck in a treatment impasse. A study to be presented at the ESMO 2018 Congre

Updated on:December 18,2023 14

Fighting racial bias in next-gen breast cancer screening

by Acoustical Society of AmericaVirtual imaging trials to investigate the impact of skin color on 3D optoacoustic tomography of the breast: (a) An example schematic of a 3D OAT scan (left) and a

Updated on: February 20,2024 11

Fighting racial bias in next-gen breast cancer screening

by Acoustical Society of AmericaVirtual imaging trials to investigate the impact of skin color on 3D optoacoustic tomography of the breast: (a) An example schematic of a 3D OAT scan (left) and a

Updated on:February 20,2024 11