New assay assesses multiple cellular pathways at once

byBaylor College of MedicineSynthetic assembly cloning for inserting multiple luciferase reporters into a single vector. Credit:Nature Communications/The Venken labA novel technological ap

Updated on: December 22,2023

New assay assesses multiple cellular pathways at once

byBaylor College of MedicineSynthetic assembly cloning for inserting multiple luciferase reporters into a single vector. Credit:Nature Communications/The Venken labA novel technological ap

Updated on:December 22,2023

Researchers uncover new clues to origins of the most common pediatric kidney cancer

by Children's Hospital Los AngelesSIX2+CITED1+ cells in hFK and WT have different transcriptional signatures. A,B) Periodic acid Schiff (PAS, left, whole image) and H&E (right, close-up i

Updated on: February 20,2024

Researchers uncover new clues to origins of the most common pediatric kidney cancer

by Children's Hospital Los AngelesSIX2+CITED1+ cells in hFK and WT have different transcriptional signatures. A,B) Periodic acid Schiff (PAS, left, whole image) and H&E (right, close-up i

Updated on:February 20,2024

Scientists describe how iron helps drive tumor development in colorectal cancer

by Michael Haederle,University of New MexicoTFRC is increased in human CRC and is positively correlated with the CTNNB1 protein expression. Detection of TFRC expression in human normal (n = 5–8)

Updated on: December 27,2023

Scientists describe how iron helps drive tumor development in colorectal cancer

by Michael Haederle,University of New MexicoTFRC is increased in human CRC and is positively correlated with the CTNNB1 protein expression. Detection of TFRC expression in human normal (n = 5–8)

Updated on:December 27,2023

A treatment for metastasis? Using ferroptosis to attack migrating cancer cells

byFriedrich–Alexander University Erlangen–NurnbergZeb1 regulates the expression of enzymes crucial for adjusting the PUFA:MUFA ratio in phospholipids. Credit:Nature Cell Biology(2024

Updated on: July 17,2024

A treatment for metastasis? Using ferroptosis to attack migrating cancer cells

byFriedrich–Alexander University Erlangen–NurnbergZeb1 regulates the expression of enzymes crucial for adjusting the PUFA:MUFA ratio in phospholipids. Credit:Nature Cell Biology(2024

Updated on:July 17,2024

A feasibility study for salvage radiation therapy in prostate cancer

by Impact Journals LLCCredit: CC0 Public DomainAn editorial paper waspublishedinOncoscienceon May 20, 2024, titled, "Deep learning-assisted lesion segmentation in PET/CT i

Updated on: July 08,2024

A feasibility study for salvage radiation therapy in prostate cancer

by Impact Journals LLCCredit: CC0 Public DomainAn editorial paper waspublishedinOncoscienceon May 20, 2024, titled, "Deep learning-assisted lesion segmentation in PET/CT i

Updated on:July 08,2024

Exposure to chemicals in drinking water associated with 5% of annual bladder cancer burden in Europe

byBarcelona Institute for Global HealthEach year, more than 6,500 cases of bladder cancer—nearly 5 percent of all cases in Europe— can be attributed to exposure to trihalomethanes (THMs) in drin

Updated on: December 20,2023

Exposure to chemicals in drinking water associated with 5% of annual bladder cancer burden in Europe

byBarcelona Institute for Global HealthEach year, more than 6,500 cases of bladder cancer—nearly 5 percent of all cases in Europe— can be attributed to exposure to trihalomethanes (THMs) in drin

Updated on:December 20,2023

CRISPR-Cas9 datasets analysis leads to largest genetic screen resource for cancer research

byWellcome Trust Sanger InstituteCredit: CC0 Public DomainA comprehensive map of genes necessary for cancer survival is one step closer, following the validation of the two largest CRISPR-Cas9 g

Updated on: December 22,2023

CRISPR-Cas9 datasets analysis leads to largest genetic screen resource for cancer research

byWellcome Trust Sanger InstituteCredit: CC0 Public DomainA comprehensive map of genes necessary for cancer survival is one step closer, following the validation of the two largest CRISPR-Cas9 g

Updated on:December 22,2023

'No one should cancel their colonoscopies': Addressing controversy from a recent clinical trial

by Leslie Orr,University of Rochester Medical CenterCredit: Unsplash/CC0 Public DomainDespite some confusing messages this week around the value of colonoscopies, Wilmot Cancer Institute physici

Updated on: December 28,2023

'No one should cancel their colonoscopies': Addressing controversy from a recent clinical trial

by Leslie Orr,University of Rochester Medical CenterCredit: Unsplash/CC0 Public DomainDespite some confusing messages this week around the value of colonoscopies, Wilmot Cancer Institute physici

Updated on:December 28,2023

Drug-resistant tuberculosis responds rapidly to bedaquiline-based second-line therapy

by Weill Cornell Medical CollegeMycobacterium tuberculosis. Credit: United States Centers for Disease Control and PreventionPatients who have drug-resistant tuberculosis (TB) have a similar micro

Updated on: May 26,2024

Drug-resistant tuberculosis responds rapidly to bedaquiline-based second-line therapy

by Weill Cornell Medical CollegeMycobacterium tuberculosis. Credit: United States Centers for Disease Control and PreventionPatients who have drug-resistant tuberculosis (TB) have a similar micro

Updated on:May 26,2024

Faulty DNA repair may lead to BRCA-linked cancers

byWeill Cornell Medical CollegeStalled replication forks (yellow arrows) are detected at the BRCA1 gene in cells containing a BRCA1 germline mutation. Credit: Weill Cornell MedicineError-prone D

Updated on: December 20,2023

Faulty DNA repair may lead to BRCA-linked cancers

byWeill Cornell Medical CollegeStalled replication forks (yellow arrows) are detected at the BRCA1 gene in cells containing a BRCA1 germline mutation. Credit: Weill Cornell MedicineError-prone D

Updated on:December 20,2023

Cellular 'waste product' rejuvenates cancer-fighting immune cells

byUT Southwestern Medical CenterUT Southwestern Simmons Cancer Center found that lactate, a metabolic byproduct produced by cells during strenuous exercise, can rejuvenate immune cells that figh

Updated on: January 10,2024

Cellular 'waste product' rejuvenates cancer-fighting immune cells

byUT Southwestern Medical CenterUT Southwestern Simmons Cancer Center found that lactate, a metabolic byproduct produced by cells during strenuous exercise, can rejuvenate immune cells that figh

Updated on:January 10,2024

Study finds 95 percent satisfaction rate with Mohs surgery

by Patrick McGee,UT Southwestern Medical CenterPatients who received Mohs surgery to treat the most serious form of skin cancer, melanoma, reported a 95 percent long-term satisfaction rate with

Updated on: December 20,2023

Study finds 95 percent satisfaction rate with Mohs surgery

by Patrick McGee,UT Southwestern Medical CenterPatients who received Mohs surgery to treat the most serious form of skin cancer, melanoma, reported a 95 percent long-term satisfaction rate with

Updated on:December 20,2023