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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Researchers identify 'switch' to activate cancer cell death

Researchers identify 'switch' to activate cancer cell death

byUC DavisAntigen-positive tumor cell (blue, left) is a direct target of CAR T-cells (light red) due to high-affinity antibody-antigen contacts. On the contrary, an antigen-negative tumor cell (

Researchers identify 'switch' to activate cancer cell death

byUC DavisAntigen-positive tumor cell (blue, left) is a direct target of CAR T-cells (light red) due to high-affinity antibody-antigen contacts. On the contrary, an antigen-negative tumor cell (
Rainbow of fruit and veg the best prevention against prostate cancer

Rainbow of fruit and veg the best prevention against prostate cancer

byUniversity of South AustraliaCredit: Unsplash/CC0 Public DomainMen who consume colorful fruits and vegetables on a regular basis are less likely to be diagnosed with prostate cancer (PC), acco

Rainbow of fruit and veg the best prevention against prostate cancer

byUniversity of South AustraliaCredit: Unsplash/CC0 Public DomainMen who consume colorful fruits and vegetables on a regular basis are less likely to be diagnosed with prostate cancer (PC), acco
Mutations in bone cells can drive leukemia in neighboring stem cells

Mutations in bone cells can drive leukemia in neighboring stem cells

Certain DNA mutations in bone cells that support blood development can drive leukemia formation in nearby blood stem cells, researchers from Winship Cancer Institute, Emory University and Children&#39

Mutations in bone cells can drive leukemia in neighboring stem cells

Certain DNA mutations in bone cells that support blood development can drive leukemia formation in nearby blood stem cells, researchers from Winship Cancer Institute, Emory University and Children&#39
Atezolizumab Plus Bevacizumab and Chemotherapy Fails to Provide PFS Benefit in Platinum-Sensitive

Atezolizumab Plus Bevacizumab and Chemotherapy Fails to Provide PFS Benefit in Platinum-Sensitive

September 13, 2023Kyle DohertyThe addition of the PD-L1 inhibitor atezolizumab to bevacizumab and platinum-based chemotherapy did not result in a statistically significant progression-free survival be

Atezolizumab Plus Bevacizumab and Chemotherapy Fails to Provide PFS Benefit in Platinum-Sensitive

September 13, 2023Kyle DohertyThe addition of the PD-L1 inhibitor atezolizumab to bevacizumab and platinum-based chemotherapy did not result in a statistically significant progression-free survival be
Imaging technique can observe specialized cancer treatment in breast cancer models

Imaging technique can observe specialized cancer treatment in breast cancer models

byJohns Hopkins University School of MedicineCredit: Unsplash/CC0 Public DomainFor nearly a century, scientific evidence has shown that the use of specific bacteria to target cancer tumors and t

Imaging technique can observe specialized cancer treatment in breast cancer models

byJohns Hopkins University School of MedicineCredit: Unsplash/CC0 Public DomainFor nearly a century, scientific evidence has shown that the use of specific bacteria to target cancer tumors and t
Targeting menin induces responses in acute leukemias with KMT2A rearrangements or NPM1 mutations

Targeting menin induces responses in acute leukemias with KMT2A rearrangements or NPM1 mutations

byUniversity of Texas M. D. Anderson Cancer CenterBone marrow aspirate showing acute myeloid leukemia. Several blasts have Auer rods. Credit: WikipediaResearchers from The University of Texas MD

Targeting menin induces responses in acute leukemias with KMT2A rearrangements or NPM1 mutations

byUniversity of Texas M. D. Anderson Cancer CenterBone marrow aspirate showing acute myeloid leukemia. Several blasts have Auer rods. Credit: WikipediaResearchers from The University of Texas MD
ATR inhibition using gartisertib in patient-derived glioblastoma cell lines

ATR inhibition using gartisertib in patient-derived glioblastoma cell lines

by Impact Journals LLCUpregulated genes and pathways enriched in glioblastoma cell lines treated with gartisertib combined with TMZ+RT. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28

ATR inhibition using gartisertib in patient-derived glioblastoma cell lines

by Impact Journals LLCUpregulated genes and pathways enriched in glioblastoma cell lines treated with gartisertib combined with TMZ+RT. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28
Long-Term Data Sustain Dabrafenib/Trametinib RFS Benefit in BRAF+ Melanoma

Long-Term Data Sustain Dabrafenib/Trametinib RFS Benefit in BRAF+ Melanoma

October 22, 2018Onclive TeamLong-term follow-up from the COMBI-AD trial continued to show a significant relapse-free survival advantage for patients with resected stage III BRAF-mutant melanoma treate

Long-Term Data Sustain Dabrafenib/Trametinib RFS Benefit in BRAF+ Melanoma

October 22, 2018Onclive TeamLong-term follow-up from the COMBI-AD trial continued to show a significant relapse-free survival advantage for patients with resected stage III BRAF-mutant melanoma treate
Key Factors to Consider in the Management of Tumor Lysis Syndrome

Key Factors to Consider in the Management of Tumor Lysis Syndrome

February 22, 2023Brittany LovelyFor patients with aggressive malignant tumors and high tumor burden, onco- logic emergencies such as tumor lysis syndrome emerge as a disease symptom or a treat- ment-r

Key Factors to Consider in the Management of Tumor Lysis Syndrome

February 22, 2023Brittany LovelyFor patients with aggressive malignant tumors and high tumor burden, onco- logic emergencies such as tumor lysis syndrome emerge as a disease symptom or a treat- ment-r
Rise in skin cancer cases underscores importance of early detection using machine learning

Rise in skin cancer cases underscores importance of early detection using machine learning

In a recent review published in theLifeJournal, a group of authors reviewed image-processing techniques in machine learning (ML) for skin cancer detection using clinical images, evaluating

Rise in skin cancer cases underscores importance of early detection using machine learning

In a recent review published in theLifeJournal, a group of authors reviewed image-processing techniques in machine learning (ML) for skin cancer detection using clinical images, evaluating
Discovery suggests new way to target mantle cell lymphoma

Discovery suggests new way to target mantle cell lymphoma

byWeill Cornell Medical CollegeThe interaction of two proteins required to regulate expression of key genes in the nucleus of mantle cell lymphoma. The red signals are generated at the interacti

Discovery suggests new way to target mantle cell lymphoma

byWeill Cornell Medical CollegeThe interaction of two proteins required to regulate expression of key genes in the nucleus of mantle cell lymphoma. The red signals are generated at the interacti
Is cold water bad for you? What about drinking from the hose or tap? The facts behind five water myths

Is cold water bad for you? What about drinking from the hose or tap? The facts behind five water myths

by Oliver A.H. Jones,The ConversationCredit: Unsplash/CC0 Public DomainWe know theimportance of staying hydrated, especially in hot weather. But even for something as simple as a drink of

Is cold water bad for you? What about drinking from the hose or tap? The facts behind five water myths

by Oliver A.H. Jones,The ConversationCredit: Unsplash/CC0 Public DomainWe know theimportance of staying hydrated, especially in hot weather. But even for something as simple as a drink of