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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Researchers uncover on/off switch for breast cancer metastasis

Researchers uncover on/off switch for breast cancer metastasis

by Rebecca McClellan,Stanford UniversitySongnan Wang (left) and Lingyin Li (right) found that a protein called ENPP1 acts as an on/off switch for breast cancer metastases. High protein levels le

Researchers uncover on/off switch for breast cancer metastasis

by Rebecca McClellan,Stanford UniversitySongnan Wang (left) and Lingyin Li (right) found that a protein called ENPP1 acts as an on/off switch for breast cancer metastases. High protein levels le
Resistance (exercise) is far from futile: The unheralded benefits of weight training

Resistance (exercise) is far from futile: The unheralded benefits of weight training

by Stuart Phillips,The ConversationCredit: CC0 Public DomainEveryone can agree that exercise is healthy. Among its many benefits, exercise improves heart and brain function, aids in controlling

Resistance (exercise) is far from futile: The unheralded benefits of weight training

by Stuart Phillips,The ConversationCredit: CC0 Public DomainEveryone can agree that exercise is healthy. Among its many benefits, exercise improves heart and brain function, aids in controlling
Extreme phenotype approach identifies rare ATR variants as potential male breast cancer susceptibility alleles

Extreme phenotype approach identifies rare ATR variants as potential male breast cancer susceptibility alleles

by Impact Journals LLCImpact of splicing variants. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28358In oncogenetics, some patients could be considered as "extreme phenotypes,&qu

Extreme phenotype approach identifies rare ATR variants as potential male breast cancer susceptibility alleles

by Impact Journals LLCImpact of splicing variants. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28358In oncogenetics, some patients could be considered as "extreme phenotypes,&qu
AI 'liquid biopsies' using cell-free DNA, protein biomarkers, could aid early detection of ovarian cancer

AI 'liquid biopsies' using cell-free DNA, protein biomarkers, could aid early detection of ovarian cancer

byJohns Hopkins University School of MedicineCredit: Carolyn Hruban, Ph.D.A blood test that uses artificial intelligence (AI) to detect cancer-related genetic changes and protein biomarkers coul

AI 'liquid biopsies' using cell-free DNA, protein biomarkers, could aid early detection of ovarian cancer

byJohns Hopkins University School of MedicineCredit: Carolyn Hruban, Ph.D.A blood test that uses artificial intelligence (AI) to detect cancer-related genetic changes and protein biomarkers coul
Proposed lung cancer screening guideline could eliminate racial disparities, allow for early detection

Proposed lung cancer screening guideline could eliminate racial disparities, allow for early detection

by Liz Murphy,Massachusetts General HospitalDistribution of smoking duration (years), smoking intensity (cigarettes per day), and pack-year smoking history among SCCS participants diagnosed with

Proposed lung cancer screening guideline could eliminate racial disparities, allow for early detection

by Liz Murphy,Massachusetts General HospitalDistribution of smoking duration (years), smoking intensity (cigarettes per day), and pack-year smoking history among SCCS participants diagnosed with
Lazarus effect in a patient treated with osimertinib for non-small cell lung cancer with leptomeningeal disease

Lazarus effect in a patient treated with osimertinib for non-small cell lung cancer with leptomeningeal disease

by Impact Journals LLCTreatment timeline with chest computed tomography (CT) and brain magnetic resonance images (MRI) on osimertinib. (A) Pretreatment CT chest, demonstrating 18 mm spiculated mass in

Lazarus effect in a patient treated with osimertinib for non-small cell lung cancer with leptomeningeal disease

by Impact Journals LLCTreatment timeline with chest computed tomography (CT) and brain magnetic resonance images (MRI) on osimertinib. (A) Pretreatment CT chest, demonstrating 18 mm spiculated mass in
Examining how gender inequalities worsen women's access to cancer prevention, detection and care

Examining how gender inequalities worsen women's access to cancer prevention, detection and care

by LancetWomen, power, and cancer: a Lancet Commission highlights how, at all these intersections with cancer, women across the globe are subject to overlapping forms of discrimination and inequi

Examining how gender inequalities worsen women's access to cancer prevention, detection and care

by LancetWomen, power, and cancer: a Lancet Commission highlights how, at all these intersections with cancer, women across the globe are subject to overlapping forms of discrimination and inequi
Magrolimab plus azacitidine results in promising activity in higher-risk MDS patients

Magrolimab plus azacitidine results in promising activity in higher-risk MDS patients

byH. Lee Moffitt Cancer Center & Research InstituteHemoglobin changes from baseline over time on treatment with magrolimab + azacitidine in patients with HR-MDS (N = 95). Data shown are medi

Magrolimab plus azacitidine results in promising activity in higher-risk MDS patients

byH. Lee Moffitt Cancer Center & Research InstituteHemoglobin changes from baseline over time on treatment with magrolimab + azacitidine in patients with HR-MDS (N = 95). Data shown are medi
Surgery first for colon cancer? Not so fast, according to new study

Surgery first for colon cancer? Not so fast, according to new study

by National Comprehensive Cancer NetworkRadiologic response, TRG, and clinical T stage. (A) Radiologic response among patients with different clinical T stage; patients with cT2–3 disease were more li

Surgery first for colon cancer? Not so fast, according to new study

by National Comprehensive Cancer NetworkRadiologic response, TRG, and clinical T stage. (A) Radiologic response among patients with different clinical T stage; patients with cT2–3 disease were more li
Guideline updated for initial management of advanced prostate cancer

Guideline updated for initial management of advanced prostate cancer

by Elana GotkineFor patients with noncastrate advanced prostate cancer, docetaxel, abiraterone, enzalutamide, apalutamide, or darolutamide are each recommended as standards of care with androgen depri

Guideline updated for initial management of advanced prostate cancer

by Elana GotkineFor patients with noncastrate advanced prostate cancer, docetaxel, abiraterone, enzalutamide, apalutamide, or darolutamide are each recommended as standards of care with androgen depri
Computer-aided detection colonoscopies tied to improved adenoma detection rate

Computer-aided detection colonoscopies tied to improved adenoma detection rate

by Elana GotkineCompared with conventional colonoscopy, computer-aided detection (CADe) system-enhanced colonoscopies have an increased rate of adenomas per colonoscopy and higher adenoma detection ra

Computer-aided detection colonoscopies tied to improved adenoma detection rate

by Elana GotkineCompared with conventional colonoscopy, computer-aided detection (CADe) system-enhanced colonoscopies have an increased rate of adenomas per colonoscopy and higher adenoma detection ra
Not all patients want faster cancer drug approvals without certainty they work

Not all patients want faster cancer drug approvals without certainty they work

byLondon School of EconomicsCredit: Pixabay/CC0 Public DomainPatients with cancer could be willing to wait for greater certainty of the benefit of new cancer drugs before they are approved by th

Not all patients want faster cancer drug approvals without certainty they work

byLondon School of EconomicsCredit: Pixabay/CC0 Public DomainPatients with cancer could be willing to wait for greater certainty of the benefit of new cancer drugs before they are approved by th