Fighting aggressive blood cancer ages and exhausts immune cells, study shows

byNottingham Trent UniversityGraphical abstract. Credit:Journal of Clinical Investigation(2022). DOI: 10.1172/JCI159579Scientists at Nottingham Trent University and John Hopkins Kimm

Updated on: January 22,2024 15

Fighting aggressive blood cancer ages and exhausts immune cells, study shows

byNottingham Trent UniversityGraphical abstract. Credit:Journal of Clinical Investigation(2022). DOI: 10.1172/JCI159579Scientists at Nottingham Trent University and John Hopkins Kimm

Updated on:January 22,2024 15

Tumor ammonia levels inhibit T cell growth, impact immunotherapy: Study

by Anna Megdell,University of MichiganGraphical abstract. Credit:Journal of Clinical Investigation(2021). DOI: 10.1172/JCI143691High levels of ammonia in tumors leads to fewer T cell

Updated on: January 21,2024 11

Tumor ammonia levels inhibit T cell growth, impact immunotherapy: Study

by Anna Megdell,University of MichiganGraphical abstract. Credit:Journal of Clinical Investigation(2021). DOI: 10.1172/JCI143691High levels of ammonia in tumors leads to fewer T cell

Updated on:January 21,2024 11

Scientists discover key 'culprits' in major lung cancer study

byUniversity of SouthamptonFibroblast identification through single-cell RNA-sequencing analysis of whole-tissue homogenates derived from human NSCLC tumor samples. a Schematic illustrating samp

Updated on: December 28,2023 10

Scientists discover key 'culprits' in major lung cancer study

byUniversity of SouthamptonFibroblast identification through single-cell RNA-sequencing analysis of whole-tissue homogenates derived from human NSCLC tumor samples. a Schematic illustrating samp

Updated on:December 28,2023 10

Vaccination with senescent cells reduces tumor formation in mice

by Karolinska InstitutetCredit: Pixabay/CC0 Public DomainCells that have permanently stopped multiplying, so-called senescent cells, could play an important role in the fight against cancer, acco

Updated on: February 01,2024 15

Vaccination with senescent cells reduces tumor formation in mice

by Karolinska InstitutetCredit: Pixabay/CC0 Public DomainCells that have permanently stopped multiplying, so-called senescent cells, could play an important role in the fight against cancer, acco

Updated on:February 01,2024 15

Breast cancer mortality reflected differently in certain Georgia neighborhoods, study reveals

by Adam Pope,University of Alabama at BirminghamAssociations Between Area Depriviation Index (ADI) and Probability of Patient Mortality for Black and White Patients With Breast Cancer. Data are

Updated on: January 30,2024 20

Breast cancer mortality reflected differently in certain Georgia neighborhoods, study reveals

by Adam Pope,University of Alabama at BirminghamAssociations Between Area Depriviation Index (ADI) and Probability of Patient Mortality for Black and White Patients With Breast Cancer. Data are

Updated on:January 30,2024 20

Study identifies new therapeutic target for tumor treatment

by Olivia Dimmer,Northwestern UniversityIntratumoral Tregcells have increased mRNA expression ofUsp22andUsp21.(AtoC) mRNA level of YFP+sorted Treg

Updated on: February 03,2024 12

Study identifies new therapeutic target for tumor treatment

by Olivia Dimmer,Northwestern UniversityIntratumoral Tregcells have increased mRNA expression ofUsp22andUsp21.(AtoC) mRNA level of YFP+sorted Treg

Updated on:February 03,2024 12

Predicting DCIS upgrade to invasive cancer at breast surgery with ultrafast imaging

by American Roentgen Ray SocietyA) Preoperative breast MRI, initial DCE post-contrast axial fat-saturated T1 axial subtraction image, demonstrates 6 cm clumped enhancement surrounding biopsy clip

Updated on: January 28,2024 16

Predicting DCIS upgrade to invasive cancer at breast surgery with ultrafast imaging

by American Roentgen Ray SocietyA) Preoperative breast MRI, initial DCE post-contrast axial fat-saturated T1 axial subtraction image, demonstrates 6 cm clumped enhancement surrounding biopsy clip

Updated on:January 28,2024 16

How nutrition guidance can optimize fertility treatments for female cancer survivors

by Drexel UniversityCredit: Pixabay/CC0 Public DomainA cancer diagnosis can increase the risk of infertility in young women. While consuming a healthy diet—including whole grains, fruits, vegetab

Updated on: February 20,2024 14

How nutrition guidance can optimize fertility treatments for female cancer survivors

by Drexel UniversityCredit: Pixabay/CC0 Public DomainA cancer diagnosis can increase the risk of infertility in young women. While consuming a healthy diet—including whole grains, fruits, vegetab

Updated on:February 20,2024 14

A four-drug chemotherapy regimen improves survival in stage 4 pancreatic cancer: Phase 3 clinical trial

byUniversity of California, Los AngelesPancreatic cancer cells (blue) growing as a sphere encased in membranes (red). Credit: National Cancer InstituteA four-drug chemotherapy regimen provided l

Updated on: January 04,2024 8

A four-drug chemotherapy regimen improves survival in stage 4 pancreatic cancer: Phase 3 clinical trial

byUniversity of California, Los AngelesPancreatic cancer cells (blue) growing as a sphere encased in membranes (red). Credit: National Cancer InstituteA four-drug chemotherapy regimen provided l

Updated on:January 04,2024 8

Genetic modifications improve the therapeutic efficacy of iPSC-derived CAR-T cells against solid tumors

by Kyoto UniversityThe CAR construct impacts the differentiation of CAR-iPSCs into T-cell lineages. a, Schematic presentation of the CAR constructs 19z, 1928z, 19bbz, 1928bbz and w/oED28z CAR (w/

Updated on: February 20,2024 19

Genetic modifications improve the therapeutic efficacy of iPSC-derived CAR-T cells against solid tumors

by Kyoto UniversityThe CAR construct impacts the differentiation of CAR-iPSCs into T-cell lineages. a, Schematic presentation of the CAR constructs 19z, 1928z, 19bbz, 1928bbz and w/oED28z CAR (w/

Updated on:February 20,2024 19

Interdisciplinary research team uses AI to quickly discover personalized cancer cures

byLouisiana State UniversityCancerOmicsNet is a graph-based AI model. The LSU research team ran it on 2,300 drugs against 359 cancer cell lines—more than 800,000 combinations. CancerOmicsNet pre

Updated on: December 28,2023 6

Interdisciplinary research team uses AI to quickly discover personalized cancer cures

byLouisiana State UniversityCancerOmicsNet is a graph-based AI model. The LSU research team ran it on 2,300 drugs against 359 cancer cell lines—more than 800,000 combinations. CancerOmicsNet pre

Updated on:December 28,2023 6

Leveraging allogeneic dendritic cells for neoantigen cancer vaccines

by Impact Journals LLCThe use of PDC*vac platform to develop NeoAg-based cancer vaccines. Credit: 2023 Hannani et al.A new research perspective was published inGenes & Canceron January

Updated on: December 28,2023 10

Leveraging allogeneic dendritic cells for neoantigen cancer vaccines

by Impact Journals LLCThe use of PDC*vac platform to develop NeoAg-based cancer vaccines. Credit: 2023 Hannani et al.A new research perspective was published inGenes & Canceron January

Updated on:December 28,2023 10