Bloomberg School Researchers Develop Universal Risk Predictor for Cardiovascular Disease

Universal risk predictor for cardiovascular disease, suitable for use in both primary and secondary prevention, would streamline risk assessmentPublishedJanuary 29, 2024EPIDEMIOLOGYResearchers from th

Updated on: February 18,2024

Bloomberg School Researchers Develop Universal Risk Predictor for Cardiovascular Disease

Universal risk predictor for cardiovascular disease, suitable for use in both primary and secondary prevention, would streamline risk assessmentPublishedJanuary 29, 2024EPIDEMIOLOGYResearchers from th

Updated on:February 18,2024

A predictive biomarker of response to therapy in patients with microsatellite stable metastatic colorectal cancer

by Vall d'Hebron Institute of OncologyA total of 166 patients with mCRCBRAF-V600Ewere included in the study from discovery (n = 46), validation (n = 52) and control (n = 68) cohorts. WES of

Updated on: January 08,2024

A predictive biomarker of response to therapy in patients with microsatellite stable metastatic colorectal cancer

by Vall d'Hebron Institute of OncologyA total of 166 patients with mCRCBRAF-V600Ewere included in the study from discovery (n = 46), validation (n = 52) and control (n = 68) cohorts. WES of

Updated on:January 08,2024

Researchers identify protein with DYRK1A-inhibiting effect that may have implications for Down syndrome

by Kyoto UniversityDYRK1A bound to FAM53C in the cytoplasm is less active. DYRK1A not bound to FAM53C in the nucleus is highly active. Functional abnormalities cause various neuropsychiatric deve

Updated on: February 20,2024

Researchers identify protein with DYRK1A-inhibiting effect that may have implications for Down syndrome

by Kyoto UniversityDYRK1A bound to FAM53C in the cytoplasm is less active. DYRK1A not bound to FAM53C in the nucleus is highly active. Functional abnormalities cause various neuropsychiatric deve

Updated on:February 20,2024

New, revised topics released in ACR appropriateness criteria

(HealthDay)—The latest edition of the American College of Radiology (ACR) Appropriateness Criteria has been released and includes 188 diagnostic imaging and interventional radiology topics, with 908 c

Updated on: May 05,2024

New, revised topics released in ACR appropriateness criteria

(HealthDay)—The latest edition of the American College of Radiology (ACR) Appropriateness Criteria has been released and includes 188 diagnostic imaging and interventional radiology topics, with 908 c

Updated on:May 05,2024

Testosterone is an ally of macrophages in the battle against adrenal cancers

byCNRSMacrophages attacking adrenal tumor in male mouse. Credit: © Julie Olabe CNRS/GReDWhy are cancers of the adrenal glands more common among women? Why are prognoses worse for them? A team of

Updated on: December 22,2023

Testosterone is an ally of macrophages in the battle against adrenal cancers

byCNRSMacrophages attacking adrenal tumor in male mouse. Credit: © Julie Olabe CNRS/GReDWhy are cancers of the adrenal glands more common among women? Why are prognoses worse for them? A team of

Updated on:December 22,2023

Chemically 'poisoned' protein acts as a molecular switch to spur cancer formation

byThe Scripps Research InstituteResearchers discovered that when the protein DNMT3B becomes S-nitrosylated in the presence of nitric oxide (NO), cancer-related genes become activated, leading to

Updated on: December 25,2023

Chemically 'poisoned' protein acts as a molecular switch to spur cancer formation

byThe Scripps Research InstituteResearchers discovered that when the protein DNMT3B becomes S-nitrosylated in the presence of nitric oxide (NO), cancer-related genes become activated, leading to

Updated on:December 25,2023

Preventing 'identity theft' in prostate cancer cells re-sensitizes them to therapy

byUT Southwestern Medical CenterJAK–STAT signaling is required for Enz resistance in TP53/RB1-deficient mCRPC.a, Heat map representing the significantly changed signaling pathways in LNCaP

Updated on: December 22,2023

Preventing 'identity theft' in prostate cancer cells re-sensitizes them to therapy

byUT Southwestern Medical CenterJAK–STAT signaling is required for Enz resistance in TP53/RB1-deficient mCRPC.a, Heat map representing the significantly changed signaling pathways in LNCaP

Updated on:December 22,2023

Enhanced tumor modeling using Laponite bioinks for 3D bioprinting

by Terasaki Institute for Biomedical InnovationScientists from the Terasaki Institute for Biomedical Innovation (TIBI) have formulated a tuneable, nanoengineered bioink for tumor modeling which contai

Updated on: January 04,2024

Enhanced tumor modeling using Laponite bioinks for 3D bioprinting

by Terasaki Institute for Biomedical InnovationScientists from the Terasaki Institute for Biomedical Innovation (TIBI) have formulated a tuneable, nanoengineered bioink for tumor modeling which contai

Updated on:January 04,2024

Clinical trial examines standard vs. extended lymph node removal for muscle-invasive bladder cancer

by SWOG Cancer Research NetworkCredit: Pixabay/CC0 Public DomainFinal results from the SWOG S1011 randomized Phase III clinical trial, published in theNew England Journal of Medicine, indicate p

Updated on: November 10,2024

Clinical trial examines standard vs. extended lymph node removal for muscle-invasive bladder cancer

by SWOG Cancer Research NetworkCredit: Pixabay/CC0 Public DomainFinal results from the SWOG S1011 randomized Phase III clinical trial, published in theNew England Journal of Medicine, indicate p

Updated on:November 10,2024

Evaluation of ruxolitinib, a JAK inhibitor, in multiple myeloma

by Impact Journals LLCRuxolitinib exerts its anti-myeloma effects through several mechanisms. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28547A new research perspective titled &quot

Updated on: May 07,2024

Evaluation of ruxolitinib, a JAK inhibitor, in multiple myeloma

by Impact Journals LLCRuxolitinib exerts its anti-myeloma effects through several mechanisms. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28547A new research perspective titled &quot

Updated on:May 07,2024

Fibroblasts involved in healing spur tumor growth in cancer

byTel Aviv UniversityCredit: Tel Aviv UniversityThe connective tissue cells known as fibroblasts are vitally important for our recovery from injury. Sensing tissue damage, they gravitate to the

Updated on: December 22,2023

Fibroblasts involved in healing spur tumor growth in cancer

byTel Aviv UniversityCredit: Tel Aviv UniversityThe connective tissue cells known as fibroblasts are vitally important for our recovery from injury. Sensing tissue damage, they gravitate to the

Updated on:December 22,2023

Precision physical activity prescriptions improve survival in colon cancer

by Pennington Biomedical Research CenterCredit: Unsplash/CC0 Public DomainPhysical activity may be associated with improved outcomes for patients undergoing postoperative treatment for Stage III colon

Updated on: December 26,2023

Precision physical activity prescriptions improve survival in colon cancer

by Pennington Biomedical Research CenterCredit: Unsplash/CC0 Public DomainPhysical activity may be associated with improved outcomes for patients undergoing postoperative treatment for Stage III colon

Updated on:December 26,2023