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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Newfound mechanism suggests drug combination could starve pancreatic cancer

Newfound mechanism suggests drug combination could starve pancreatic cancer

byNYU Langone HealthPancreatic cancer cells (blue) growing as a sphere encased in membranes (red). Credit: National Cancer InstituteA new combination of treatments safely decreased growth of pan

Newfound mechanism suggests drug combination could starve pancreatic cancer

byNYU Langone HealthPancreatic cancer cells (blue) growing as a sphere encased in membranes (red). Credit: National Cancer InstituteA new combination of treatments safely decreased growth of pan
Carbon oxide gas boosts photothermal therapy under mild temperature

Carbon oxide gas boosts photothermal therapy under mild temperature

by ZHANG Nannan,Chinese Academy of SciencesSchematic illustration of (A) synthesis route of mPEG(CO) and (B) the nanobomb consist of mPEG(CO) and PBPTV. (C) Schematic illustration of low-tempera

Carbon oxide gas boosts photothermal therapy under mild temperature

by ZHANG Nannan,Chinese Academy of SciencesSchematic illustration of (A) synthesis route of mPEG(CO) and (B) the nanobomb consist of mPEG(CO) and PBPTV. (C) Schematic illustration of low-tempera
First immunotherapy success for triple-negative breast cancer

First immunotherapy success for triple-negative breast cancer

byQueen Mary, University of LondonThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014 by

First immunotherapy success for triple-negative breast cancer

byQueen Mary, University of LondonThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014 by
Discovery of small molecule Gαq/11 protein inhibitors against uveal melanoma

Discovery of small molecule Gαq/11 protein inhibitors against uveal melanoma

by Compuscript LtdGraphical abstract:Constitutively activated Gαq/11 proteins drive the vast majority of uveal melanoma (UM). GQ262 effectively combats UM both in vitro and in vivo by targeting Gαq/11

Discovery of small molecule Gαq/11 protein inhibitors against uveal melanoma

by Compuscript LtdGraphical abstract:Constitutively activated Gαq/11 proteins drive the vast majority of uveal melanoma (UM). GQ262 effectively combats UM both in vitro and in vivo by targeting Gαq/11
High-dose IV vitamin C plus chemotherapy found to double survival time in advanced pancreatic cancer

High-dose IV vitamin C plus chemotherapy found to double survival time in advanced pancreatic cancer

by Jennifer Brown,University of IowaGraphical abstract. Credit:Redox Biology(2024). DOI: 10.1016/j.redox.2024.103375Results from a randomized, phase 2 clinical trial show that adding

High-dose IV vitamin C plus chemotherapy found to double survival time in advanced pancreatic cancer

by Jennifer Brown,University of IowaGraphical abstract. Credit:Redox Biology(2024). DOI: 10.1016/j.redox.2024.103375Results from a randomized, phase 2 clinical trial show that adding
Breast cancer deaths fall 44% since 1989 despite rising cases

Breast cancer deaths fall 44% since 1989 despite rising cases

Credit: Pixabay/CC0 Public DomainBreast cancer rates in the United States are increasing significantly, with younger women and Asian Americans experiencing the most notable rises, according to a study

Breast cancer deaths fall 44% since 1989 despite rising cases

Credit: Pixabay/CC0 Public DomainBreast cancer rates in the United States are increasing significantly, with younger women and Asian Americans experiencing the most notable rises, according to a study
Using the immune system to fight cancer: an interview with Dr Charles Akle

Using the immune system to fight cancer: an interview with Dr Charles Akle

Why does cancer occur?We all produce as many as 100,000 different types of cancer cells every day, which are recognized and eliminated by our extraordinarily efficient immune system.However, if someth

Using the immune system to fight cancer: an interview with Dr Charles Akle

Why does cancer occur?We all produce as many as 100,000 different types of cancer cells every day, which are recognized and eliminated by our extraordinarily efficient immune system.However, if someth
Marker for therapy response in acute myeloid leukemia identified

Marker for therapy response in acute myeloid leukemia identified

byGerman Cancer Research CenterCell line sensitivity and additional patient data. A IC50s for VEN of 19 AML cell lines classified as primitive (Prim-AML, n = 11) or monocytic (Mono-AML, n = 8) t

Marker for therapy response in acute myeloid leukemia identified

byGerman Cancer Research CenterCell line sensitivity and additional patient data. A IC50s for VEN of 19 AML cell lines classified as primitive (Prim-AML, n = 11) or monocytic (Mono-AML, n = 8) t
Controlling a cancer-associated gene can mimic muscle growth from exercise

Controlling a cancer-associated gene can mimic muscle growth from exercise

byUniversity of ArkansasTranscriptional similarities between human RE recovery and MYC overexpression in mouse plantaris muscle. Credit:EMBO Reports(2024). DOI: 10.1038/s44319-024-00

Controlling a cancer-associated gene can mimic muscle growth from exercise

byUniversity of ArkansasTranscriptional similarities between human RE recovery and MYC overexpression in mouse plantaris muscle. Credit:EMBO Reports(2024). DOI: 10.1038/s44319-024-00
Patients prefer stool test to colonoscopy

Patients prefer stool test to colonoscopy

byCedars-Sinai Medical CenterGraphical abstract. Credit:Clinical Gastroenterology and Hepatology(2022). DOI: 10.1016/j.cgh.2022.07.012Three-quarters of people prefer to do a fecal im

Patients prefer stool test to colonoscopy

byCedars-Sinai Medical CenterGraphical abstract. Credit:Clinical Gastroenterology and Hepatology(2022). DOI: 10.1016/j.cgh.2022.07.012Three-quarters of people prefer to do a fecal im
Researchers identify new therapeutic target for colorectal cancer

Researchers identify new therapeutic target for colorectal cancer

byRockefeller University PressCancer—Histopathologic image of colonic carcinoid. Credit: Wikipedia/CC BY-SA 3.0Researchers at the University of Toronto have identified a key protein that support

Researchers identify new therapeutic target for colorectal cancer

byRockefeller University PressCancer—Histopathologic image of colonic carcinoid. Credit: Wikipedia/CC BY-SA 3.0Researchers at the University of Toronto have identified a key protein that support
Research reveals how synthesized plankton molecules inhibit cancer proteins

Research reveals how synthesized plankton molecules inhibit cancer proteins

by Justin Jackson , Medical Xpressa, Chemical structure of reported PA and PB (in beige), and the revised structure of PB (in blue) in this work. b, A retrosynthesis targeting a minimally oxidized int

Research reveals how synthesized plankton molecules inhibit cancer proteins

by Justin Jackson , Medical Xpressa, Chemical structure of reported PA and PB (in beige), and the revised structure of PB (in blue) in this work. b, A retrosynthesis targeting a minimally oxidized int