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Medical research
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Cell's 'garbage disposal' may have another role: Helping neurons near skin sense the environment

Cell's 'garbage disposal' may have another role: Helping neurons near skin sense the environment

byJohns Hopkins University School of MedicineNeuronal membrane proteasomes are labeled with a red compound and appear in a subset of sensory neurons that are labeled with green compound. Note, n

Cell's 'garbage disposal' may have another role: Helping neurons near skin sense the environment

byJohns Hopkins University School of MedicineNeuronal membrane proteasomes are labeled with a red compound and appear in a subset of sensory neurons that are labeled with green compound. Note, n
Scientists uncover key resistance mechanism to Wnt inhibitors in pancreatic and colorectal cancers

Scientists uncover key resistance mechanism to Wnt inhibitors in pancreatic and colorectal cancers

byDuke-NUS Medical SchoolDuke-NUS scientists show that FBXW7-mutant cancers are resistant to Wnt inhibitors by comparing the impact Wnt inhibitor ETC-159 has on cancer cells with and without FBX

Scientists uncover key resistance mechanism to Wnt inhibitors in pancreatic and colorectal cancers

byDuke-NUS Medical SchoolDuke-NUS scientists show that FBXW7-mutant cancers are resistant to Wnt inhibitors by comparing the impact Wnt inhibitor ETC-159 has on cancer cells with and without FBX
Working conditions can explain educational differences in heart disease mortality

Working conditions can explain educational differences in heart disease mortality

byKarolinska InstitutetCredit: Pixabay/CC0 Public DomainResearchers from the Institute of Environmental Medicine at Karolinska Institutet have found that low influence and opportunities for deve

Working conditions can explain educational differences in heart disease mortality

byKarolinska InstitutetCredit: Pixabay/CC0 Public DomainResearchers from the Institute of Environmental Medicine at Karolinska Institutet have found that low influence and opportunities for deve
Researchers shed light on the molecular causes of different functions of opioid receptors

Researchers shed light on the molecular causes of different functions of opioid receptors

by Anne Grimm,Leipzig UniversityLigand-dependent activation of the µOR.a, Binding of agonist to the µOR activates two downstream signaling pathways: the G-protein pathway and the β-arresti

Researchers shed light on the molecular causes of different functions of opioid receptors

by Anne Grimm,Leipzig UniversityLigand-dependent activation of the µOR.a, Binding of agonist to the µOR activates two downstream signaling pathways: the G-protein pathway and the β-arresti
Study finds embryos in hungry mouse moms postpone development

Study finds embryos in hungry mouse moms postpone development

byThe Company of BiologistsA mouse embryo (blastocyst) that has paused its development due to nutrient depletion. Credit: Jiajia YeIt's challenging to sustain a pregnancy when food is short,

Study finds embryos in hungry mouse moms postpone development

byThe Company of BiologistsA mouse embryo (blastocyst) that has paused its development due to nutrient depletion. Credit: Jiajia YeIt's challenging to sustain a pregnancy when food is short,
Preparing for the next health crisis: COVID-19 showed the importance of community-engaged research

Preparing for the next health crisis: COVID-19 showed the importance of community-engaged research

by Simran Purewal and Julia Smith,The ConversationCredit: CC0 Public DomainCommunity-engaged researchinvolves the active and meaningful involvement of people directly affected by a researc

Preparing for the next health crisis: COVID-19 showed the importance of community-engaged research

by Simran Purewal and Julia Smith,The ConversationCredit: CC0 Public DomainCommunity-engaged researchinvolves the active and meaningful involvement of people directly affected by a researc
Male infertility genetic study improves molecular diagnostics and personalized management of patients

Male infertility genetic study improves molecular diagnostics and personalized management of patients

by Estonian Research CouncilDNA samples in Estonian Biobank. Photo by Renee Altrov. Credit: Renee AltrovApproximately one in seven couples face difficulties conceiving a child naturally. Half of these

Male infertility genetic study improves molecular diagnostics and personalized management of patients

by Estonian Research CouncilDNA samples in Estonian Biobank. Photo by Renee Altrov. Credit: Renee AltrovApproximately one in seven couples face difficulties conceiving a child naturally. Half of these
Study identifies novel mechanism of glucose sensing by adipocytes in regulating thermogenesis and energy metabolism

Study identifies novel mechanism of glucose sensing by adipocytes in regulating thermogenesis and energy metabolism

by Liu Jia,Chinese Academy of SciencesThe proposed model for glucose sensing via CREBZF in the regulation of thermogenesis and energy homeostasis in adipose tissues. Targeting CREBZF may provide

Study identifies novel mechanism of glucose sensing by adipocytes in regulating thermogenesis and energy metabolism

by Liu Jia,Chinese Academy of SciencesThe proposed model for glucose sensing via CREBZF in the regulation of thermogenesis and energy homeostasis in adipose tissues. Targeting CREBZF may provide
Transmission risk of multidrug-resistant bacteria appears highest in hospital sinks

Transmission risk of multidrug-resistant bacteria appears highest in hospital sinks

by Association for Professionals in Infection ControlCredit: CC0 Public DomainA newstudypublished today in theAmerican Journal of Infection Control (AJIC)reports the infection

Transmission risk of multidrug-resistant bacteria appears highest in hospital sinks

by Association for Professionals in Infection ControlCredit: CC0 Public DomainA newstudypublished today in theAmerican Journal of Infection Control (AJIC)reports the infection
Researchers advance understanding of Parkinson's disease

Researchers advance understanding of Parkinson's disease

byUniversity of GalwaySchematic representation of the experimental design and procedures followed in this study. The study was designed for the region-specific and temporal characterization of t

Researchers advance understanding of Parkinson's disease

byUniversity of GalwaySchematic representation of the experimental design and procedures followed in this study. The study was designed for the region-specific and temporal characterization of t
Coronary sinus reducer relieves angina, but how it works remains unclear

Coronary sinus reducer relieves angina, but how it works remains unclear

byAmerican College of CardiologyCredit: Towfiqu barbhuiya from PexelsPeople with chronic chest pain who received a coronary sinus reducer (CSR)—a stent thought to increase the amount of oxygen-r

Coronary sinus reducer relieves angina, but how it works remains unclear

byAmerican College of CardiologyCredit: Towfiqu barbhuiya from PexelsPeople with chronic chest pain who received a coronary sinus reducer (CSR)—a stent thought to increase the amount of oxygen-r
Serious flu damage prevented by compound that blocks unnecessary cell death

Serious flu damage prevented by compound that blocks unnecessary cell death

byTufts UniversityCredit: Pixabay/CC0 Public DomainAs lung cells are killed by the influenza virus, they burst open, releasing molecular signals that trigger the immune cells that can combat the

Serious flu damage prevented by compound that blocks unnecessary cell death

byTufts UniversityCredit: Pixabay/CC0 Public DomainAs lung cells are killed by the influenza virus, they burst open, releasing molecular signals that trigger the immune cells that can combat the