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New insight into the protein mutations that cause Rett syndrome

New insight into the protein mutations that cause Rett syndrome

byRockefeller UniversityWorking model for normal MeCP2 function on chromatin and its dysregulation in disease. Credit:Nature Structural & Molecular Biology(2024). DOI: 10.1038/s4

New insight into the protein mutations that cause Rett syndrome

byRockefeller UniversityWorking model for normal MeCP2 function on chromatin and its dysregulation in disease. Credit:Nature Structural & Molecular Biology(2024). DOI: 10.1038/s4
Bridging diet, microbes, and metabolism: Implications for metabolic disorders

Bridging diet, microbes, and metabolism: Implications for metabolic disorders

FEBRUARY 20, 2024byBoyce Thompson InstituteTransgenic animals expressing a green fluorescent protein attached to the fatty acid desaturase, FAT-7. Green color represents the induction of FAT-7 i

Bridging diet, microbes, and metabolism: Implications for metabolic disorders

FEBRUARY 20, 2024byBoyce Thompson InstituteTransgenic animals expressing a green fluorescent protein attached to the fatty acid desaturase, FAT-7. Green color represents the induction of FAT-7 i
FDA Approves Lymphir: A New Hope for CTCL Patients

FDA Approves Lymphir: A New Hope for CTCL Patients

The U.S. Food and Drug Administration (FDA) had approved Lymphir (denileukin diftitox-cxdl), a novel immunotherapy for the treatment of relapsed or refractory cutaneous T-cell lymphoma (CTCL) after at least one prior systemic therapy.

FDA Approves Lymphir: A New Hope for CTCL Patients

The U.S. Food and Drug Administration (FDA) had approved Lymphir (denileukin diftitox-cxdl), a novel immunotherapy for the treatment of relapsed or refractory cutaneous T-cell lymphoma (CTCL) after at least one prior systemic therapy.
Circuit-specific gene therapy brings new hope for treatment of Parkinson's disease

Circuit-specific gene therapy brings new hope for treatment of Parkinson's disease

byChinese Academy of SciencesRetrograde AAV selectively targets D1-MSNs and rescues parkinsonian symptoms with chemogenetic modulation. Credit: SIATResearchers from the Shenzhen Institute of Adv

Circuit-specific gene therapy brings new hope for treatment of Parkinson's disease

byChinese Academy of SciencesRetrograde AAV selectively targets D1-MSNs and rescues parkinsonian symptoms with chemogenetic modulation. Credit: SIATResearchers from the Shenzhen Institute of Adv
Team assesses biological functions, diseases and therapeutic targets of heat shock protein 90

Team assesses biological functions, diseases and therapeutic targets of heat shock protein 90

by Sichuan International Medical Exchange and Promotion AssociationHSP90 chaperone undergoes dynamic cycling process: HSP90 transits between open and closed states to promote maturation of polypeptide

Team assesses biological functions, diseases and therapeutic targets of heat shock protein 90

by Sichuan International Medical Exchange and Promotion AssociationHSP90 chaperone undergoes dynamic cycling process: HSP90 transits between open and closed states to promote maturation of polypeptide
Genetic diseases: How scientists are working to make DNA repair (almost) a piece of cake

Genetic diseases: How scientists are working to make DNA repair (almost) a piece of cake

FEBRUARY 6, 2024by Camille Bouchard,The ConversationCredit: Unsplash/CC0 Public DomainI have always been fascinated by genetics, a branch of biology that helps explain everything from the striki

Genetic diseases: How scientists are working to make DNA repair (almost) a piece of cake

FEBRUARY 6, 2024by Camille Bouchard,The ConversationCredit: Unsplash/CC0 Public DomainI have always been fascinated by genetics, a branch of biology that helps explain everything from the striki
New wearable patch measures trace perspiration during activity and rest

New wearable patch measures trace perspiration during activity and rest

byUniversity of TsukubaConceptual illustration portrays fully assembled patch securely affixed to skin's surface. Credit:Advanced Science(2024). DOI: 10.1002/advs.202401947Resear

New wearable patch measures trace perspiration during activity and rest

byUniversity of TsukubaConceptual illustration portrays fully assembled patch securely affixed to skin's surface. Credit:Advanced Science(2024). DOI: 10.1002/advs.202401947Resear
Atezolizumab addition to chemotherapy after surgery does not improve survival for triple negative breast cancer: Study

Atezolizumab addition to chemotherapy after surgery does not improve survival for triple negative breast cancer: Study

by European Organisation for Research and Treatment of CancerCredit: Unsplash/CC0 Public DomainPatients with triple-negative breast cancer do not benefit from the addition of atezolizumab to their pos

Atezolizumab addition to chemotherapy after surgery does not improve survival for triple negative breast cancer: Study

by European Organisation for Research and Treatment of CancerCredit: Unsplash/CC0 Public DomainPatients with triple-negative breast cancer do not benefit from the addition of atezolizumab to their pos
How corporate involvement in psychedelic research could threaten public safety

How corporate involvement in psychedelic research could threaten public safety

by Elena Koning, Elisa Brietzke and Marco Solmi,The ConversationCredit: Unsplash/CC0 Public DomainIn the mid-20th century,psychedelicswere deemed illegal substances with little medic

How corporate involvement in psychedelic research could threaten public safety

by Elena Koning, Elisa Brietzke and Marco Solmi,The ConversationCredit: Unsplash/CC0 Public DomainIn the mid-20th century,psychedelicswere deemed illegal substances with little medic
A potential method for interrupting the misfolding of tau protein that underlies neurodegenerative disease

A potential method for interrupting the misfolding of tau protein that underlies neurodegenerative disease

by Sonia Fernandez,University of California - Santa BarbaraInvestigation of the effect of VHH Z70 nanobody on jR2R3 P301L-induced tau fibrillization in cells. Credit:Proceedings of the Nat

A potential method for interrupting the misfolding of tau protein that underlies neurodegenerative disease

by Sonia Fernandez,University of California - Santa BarbaraInvestigation of the effect of VHH Z70 nanobody on jR2R3 P301L-induced tau fibrillization in cells. Credit:Proceedings of the Nat
New insight into dying cells in Parkinson's disease

New insight into dying cells in Parkinson's disease

APRIL 25, 2023by Birgitte Svennevig, University of Southern DenmarkGraphical Abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112180When a patient experiences the first symp

New insight into dying cells in Parkinson's disease

APRIL 25, 2023by Birgitte Svennevig, University of Southern DenmarkGraphical Abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112180When a patient experiences the first symp
Study suggests statins could help fight gum disease

Study suggests statins could help fight gum disease

byAmerican Society for Biochemistry and Molecular BiologyCredit: Pixabay/CC0 Public DomainCould taking statins benefit your mouth in addition to your arteries? A new study conducted in cell cult

Study suggests statins could help fight gum disease

byAmerican Society for Biochemistry and Molecular BiologyCredit: Pixabay/CC0 Public DomainCould taking statins benefit your mouth in addition to your arteries? A new study conducted in cell cult