Structural analysis of relevant drug targets for Alzheimer's disease

by Bentham Science PublishersAlzheimer's Disease (AD) is classified as a neurodegenerative non-curable disease that affects millions worldwide. Current drugs have side effects that are significant

Updated on: March 07,2024

Structural analysis of relevant drug targets for Alzheimer's disease

by Bentham Science PublishersAlzheimer's Disease (AD) is classified as a neurodegenerative non-curable disease that affects millions worldwide. Current drugs have side effects that are significant

Updated on:March 07,2024

Llama nanobodies: New therapy can neutralize a wide variety of HIV-1 strains

by Noelle Toumey Reetz,Georgia State UniversityCryo-EM structures of nanobodies R27 and G36 in complex with HIV-1 Env trimer reveal modes of recognition similar to J3. Credit:Advanced Scie

Updated on: August 01,2024

Llama nanobodies: New therapy can neutralize a wide variety of HIV-1 strains

by Noelle Toumey Reetz,Georgia State UniversityCryo-EM structures of nanobodies R27 and G36 in complex with HIV-1 Env trimer reveal modes of recognition similar to J3. Credit:Advanced Scie

Updated on:August 01,2024

How antidepressants, ketamine and psychedelic drugs may make brains more flexible—new research

by Barbara Jacquelyn Sahakian and Christelle Langley,The ConversationCredit: Juan Gaertner/ShutterstockThe first-line pharmacological treatment for major depressive disorder (MDD) are antidepres

Updated on: January 12,2024

How antidepressants, ketamine and psychedelic drugs may make brains more flexible—new research

by Barbara Jacquelyn Sahakian and Christelle Langley,The ConversationCredit: Juan Gaertner/ShutterstockThe first-line pharmacological treatment for major depressive disorder (MDD) are antidepres

Updated on:January 12,2024

Alzheimer's drug trial targets toxic proteases from gum disease bacteria in the brain

by Alzheimer's Research UKP. gingivalis colonies grown on blood agar. CC0 Public DomainThe pharmaceutical company, Cortexyme, Inc. has outlined a trial of potential Alzheimer's drug that

Updated on: April 16,2024

Alzheimer's drug trial targets toxic proteases from gum disease bacteria in the brain

by Alzheimer's Research UKP. gingivalis colonies grown on blood agar. CC0 Public DomainThe pharmaceutical company, Cortexyme, Inc. has outlined a trial of potential Alzheimer's drug that

Updated on:April 16,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on: March 02,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on:March 02,2024

Landmark study finds dementia risk varies significantly among racial and ethnic groups

by Kaiser PermanenteDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.In the largest and longest study thus far of ethnic disparities in dementia risk

Updated on: February 27,2024

Landmark study finds dementia risk varies significantly among racial and ethnic groups

by Kaiser PermanenteDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.In the largest and longest study thus far of ethnic disparities in dementia risk

Updated on:February 27,2024

Study shows activity of claustrum neurons controls alertness level, engagement of sensory information

byHebrew University of JerusalemApproach for hM3Dq DREADD experiments (left) and setup (right). Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-48829-6A new study has unc

Updated on: July 08,2024

Study shows activity of claustrum neurons controls alertness level, engagement of sensory information

byHebrew University of JerusalemApproach for hM3Dq DREADD experiments (left) and setup (right). Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-48829-6A new study has unc

Updated on:July 08,2024

Poor neighborhoods linked to elevated dementia risk and faster brain aging

by Duke UniversityCredit: CC0 Public DomainLiving in a poorer neighborhood is linked to accelerated brain aging and increased dementia risk early in life, regardless of income level or education,

Updated on: March 19,2024

Poor neighborhoods linked to elevated dementia risk and faster brain aging

by Duke UniversityCredit: CC0 Public DomainLiving in a poorer neighborhood is linked to accelerated brain aging and increased dementia risk early in life, regardless of income level or education,

Updated on:March 19,2024

New research uncovers brain changes in Parkinson's disease

Updated on: March 09,2025

New research uncovers brain changes in Parkinson's disease

Updated on:March 09,2025

Development of plaques in Alzheimer's disease resolved

by Ruhr-Universitaet-BochumDominik Röhr researches proteins that are altered in Alzheimer’s disease. Credit: Michael SchwettmannA team of researchers from Ruhr-Universität Bochum (RUB) and Vrije

Updated on: April 02,2024

Development of plaques in Alzheimer's disease resolved

by Ruhr-Universitaet-BochumDominik Röhr researches proteins that are altered in Alzheimer’s disease. Credit: Michael SchwettmannA team of researchers from Ruhr-Universität Bochum (RUB) and Vrije

Updated on:April 02,2024

Women's blood lipid metabolism found to be better at countering effects of sleep apnea

by University of OttawaSubjects were seated for six hours with an intravenous catheter to measure blood lipids, breathing medical nitrogen to simulate sleep apnea. Credit: University of OttawaSle

Updated on: March 05,2024

Women's blood lipid metabolism found to be better at countering effects of sleep apnea

by University of OttawaSubjects were seated for six hours with an intravenous catheter to measure blood lipids, breathing medical nitrogen to simulate sleep apnea. Credit: University of OttawaSle

Updated on:March 05,2024

Dementia patients' adult kids diagnosed earlier than their parents

by Tamara Bhandari,Washington University School of MedicineCredit: CC0 Public DomainA person's chance of developing dementia is influenced by family history, variations in certain genes, and

Updated on: May 06,2024

Dementia patients' adult kids diagnosed earlier than their parents

by Tamara Bhandari,Washington University School of MedicineCredit: CC0 Public DomainA person's chance of developing dementia is influenced by family history, variations in certain genes, and

Updated on:May 06,2024