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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Researchers demonstrate RAS dimers are essential for cancer

Researchers demonstrate RAS dimers are essential for cancer

by Cathy Frisinger,UT Southwestern Medical CenterRAS oncogenes work in pairs, known as "dimers." Credit: UT SouthwesternMutated RAS genes are some of the most common genetic drivers of

Researchers demonstrate RAS dimers are essential for cancer

by Cathy Frisinger,UT Southwestern Medical CenterRAS oncogenes work in pairs, known as "dimers." Credit: UT SouthwesternMutated RAS genes are some of the most common genetic drivers of
One in five GPs unwilling to prescribe aspirin to people at risk of bowel cancer, finds UK study

One in five GPs unwilling to prescribe aspirin to people at risk of bowel cancer, finds UK study

by University of LeedsCredit: Unsplash/CC0 Public DomainOne in five GPs could be unwilling to prescribe aspirin to patients with a cancer-causing syndrome, despite national guidelines advising it

One in five GPs unwilling to prescribe aspirin to people at risk of bowel cancer, finds UK study

by University of LeedsCredit: Unsplash/CC0 Public DomainOne in five GPs could be unwilling to prescribe aspirin to patients with a cancer-causing syndrome, despite national guidelines advising it
Exploring ferroptosis and its implications in lung cancer

Exploring ferroptosis and its implications in lung cancer

by Cactus CommunicationsEven with advances in diagnosis and treatments, the survival rate of patients with lung cancer, remains to be low. Ferroptosis is a type of iron-dependent programmed cell death

Exploring ferroptosis and its implications in lung cancer

by Cactus CommunicationsEven with advances in diagnosis and treatments, the survival rate of patients with lung cancer, remains to be low. Ferroptosis is a type of iron-dependent programmed cell death
Pathway tied to cancer-driving genome alterations identified

Pathway tied to cancer-driving genome alterations identified

byUTSouthwestern Medical CenterThese images show examples of mitotic chromosome spreads from human cancer cells containing a shattered chromosome (left panel) or extrachromosomal DNA (midd

Pathway tied to cancer-driving genome alterations identified

byUTSouthwestern Medical CenterThese images show examples of mitotic chromosome spreads from human cancer cells containing a shattered chromosome (left panel) or extrachromosomal DNA (midd
Team studies association between tumor mutations and meningioma recurrence in Grade I/II disease

Team studies association between tumor mutations and meningioma recurrence in Grade I/II disease

by Impact JournalsAdjusted progression-free survival hazard ratios for genes examined. Credit: 2022 Dullea et al.A new research paper titled "Association between tumor mutations and meningioma re

Team studies association between tumor mutations and meningioma recurrence in Grade I/II disease

by Impact JournalsAdjusted progression-free survival hazard ratios for genes examined. Credit: 2022 Dullea et al.A new research paper titled "Association between tumor mutations and meningioma re
Telisotuzumab vedotin shows durable response in some Asian patients with nonsquamous NSCLC

Telisotuzumab vedotin shows durable response in some Asian patients with nonsquamous NSCLC

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainThe c-Met-directed antibody-drug conjugate telisotuzumab vedotin demonstrated durable responses and an accepta

Telisotuzumab vedotin shows durable response in some Asian patients with nonsquamous NSCLC

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainThe c-Met-directed antibody-drug conjugate telisotuzumab vedotin demonstrated durable responses and an accepta
Polyploidy study reveals why some cancers are resistant to therapeutic drugs

Polyploidy study reveals why some cancers are resistant to therapeutic drugs

byOsaka UniversityOverview of the study. (A) We created unique cells with double the usual number of chromosomes to investigate the relationship between polyploidy and DNA damage. (B) After trea

Polyploidy study reveals why some cancers are resistant to therapeutic drugs

byOsaka UniversityOverview of the study. (A) We created unique cells with double the usual number of chromosomes to investigate the relationship between polyploidy and DNA damage. (B) After trea
Leveraging allogeneic dendritic cells for neoantigen cancer vaccines

Leveraging allogeneic dendritic cells for neoantigen cancer vaccines

by Impact Journals LLCThe use of PDC*vac platform to develop NeoAg-based cancer vaccines. Credit: 2023 Hannani et al.A new research perspective was published inGenes & Canceron January

Leveraging allogeneic dendritic cells for neoantigen cancer vaccines

by Impact Journals LLCThe use of PDC*vac platform to develop NeoAg-based cancer vaccines. Credit: 2023 Hannani et al.A new research perspective was published inGenes & Canceron January
Tumor macrophage marker offers unique target for treatment

Tumor macrophage marker offers unique target for treatment

by National Institutes of HealthA nanoparticle attached to CRV (CRV-NP) specifically homed to macrophages in breast tumors in mice (yellow arrow) and did not home to spleen, lung or heart. Nanopa

Tumor macrophage marker offers unique target for treatment

by National Institutes of HealthA nanoparticle attached to CRV (CRV-NP) specifically homed to macrophages in breast tumors in mice (yellow arrow) and did not home to spleen, lung or heart. Nanopa
Long-term study supports link between inflammation and cognitive problems in older breast cancer survivors

Long-term study supports link between inflammation and cognitive problems in older breast cancer survivors

by University of California, Los AngelesCredit: Pixabay/CC0 Public DomainScientists are still trying to understand why many breast cancer survivors experience troubling cognitive problems for yea

Long-term study supports link between inflammation and cognitive problems in older breast cancer survivors

by University of California, Los AngelesCredit: Pixabay/CC0 Public DomainScientists are still trying to understand why many breast cancer survivors experience troubling cognitive problems for yea
Obesity-linked cancers on the rise in young adults

Obesity-linked cancers on the rise in young adults

Credit: CC0 Public DomainA sharp increase in obesity-linked cancers among young adults in the United States could foreshadow a reversal in the overall decline in cancer mortality, researchers warned M

Obesity-linked cancers on the rise in young adults

Credit: CC0 Public DomainA sharp increase in obesity-linked cancers among young adults in the United States could foreshadow a reversal in the overall decline in cancer mortality, researchers warned M
Artificial intelligence tool developed to predict risk of lung cancer

Artificial intelligence tool developed to predict risk of lung cancer

byMassachusetts General HospitalCredit: CC0 Public DomainLung cancer is the leading cause of cancer death in the United States and around the world. Low-dose chest computed tomography (LDCT) is

Artificial intelligence tool developed to predict risk of lung cancer

byMassachusetts General HospitalCredit: CC0 Public DomainLung cancer is the leading cause of cancer death in the United States and around the world. Low-dose chest computed tomography (LDCT) is