Exploring complement system response to adeno-associated virus vector gene therapy

by Kathryn Ryan,Mary Ann Liebert, IncCredit: CC0 Public DomainRecent clinical trials utilizing high doses of adeno-associated virus (AAV) vectors have highlighted a new challenge to AAV gene tra

Breakthroughs June 18,2024

Exploring complement system response to adeno-associated virus vector gene therapy

by Kathryn Ryan,Mary Ann Liebert, IncCredit: CC0 Public DomainRecent clinical trials utilizing high doses of adeno-associated virus (AAV) vectors have highlighted a new challenge to AAV gene tra

Breakthroughs June 18,2024

Could a computer diagnose Alzheimer's disease and dementia?

by Gina Mantica,Boston UniversityCredit: Pixabay/CC0 Public DomainIt takes a lot of time—and money—to diagnose Alzheimer's disease. After running lengthy in-person neuropsychological exams,

Neurology June 18,2024

Could a computer diagnose Alzheimer's disease and dementia?

by Gina Mantica,Boston UniversityCredit: Pixabay/CC0 Public DomainIt takes a lot of time—and money—to diagnose Alzheimer's disease. After running lengthy in-person neuropsychological exams,

Neurology June 18,2024

Computer simulations explore how Alzheimer's disease starts

by Rice UniversityA team of Rice University researchers built computer simulations of amyloid beta proteins to see what their energy landscapes reveal about the formation of plaques in patients w

Neurology June 18,2024

Computer simulations explore how Alzheimer's disease starts

by Rice UniversityA team of Rice University researchers built computer simulations of amyloid beta proteins to see what their energy landscapes reveal about the formation of plaques in patients w

Neurology June 18,2024

'Viral relicts' in the genome could fuel neurodegeneration

by Marcus Neitzert, Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)Different HERV glycoproteins increase intercellular protein aggregate spreading.aExperimental workflow.

Neurology June 18,2024

'Viral relicts' in the genome could fuel neurodegeneration

by Marcus Neitzert, Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)Different HERV glycoproteins increase intercellular protein aggregate spreading.aExperimental workflow.

Neurology June 18,2024

The link between memory perceptions and Alzheimer's risk

by Kristie Auman-Bauer,Pennsylvania State UniversityCredit: AI-generated imageOver 20 percent of older adults suffer from subjective memory impairment, where a person reports having trouble reme

Neurology June 18,2024

The link between memory perceptions and Alzheimer's risk

by Kristie Auman-Bauer,Pennsylvania State UniversityCredit: AI-generated imageOver 20 percent of older adults suffer from subjective memory impairment, where a person reports having trouble reme

Neurology June 18,2024

New treatments for Alzheimer's and stroke revealed in several new studies

by American Physiological SocietyCredit: Pixabay/CC0 Public DomainThe results of three new studies indicate there could be new treatments for Alzheimer's and stroke. One study reveals a possi

Neurology June 18,2024

New treatments for Alzheimer's and stroke revealed in several new studies

by American Physiological SocietyCredit: Pixabay/CC0 Public DomainThe results of three new studies indicate there could be new treatments for Alzheimer's and stroke. One study reveals a possi

Neurology June 18,2024

Poorer schools could bring higher dementia rates many decades later

by Alan MozesWhat do race and early education have to do with dementia risk among seniors?Quite a bit, a new study suggests.Researchers spent decades tracking the onset ofdementiaamong nea

Neurology June 18,2024

Poorer schools could bring higher dementia rates many decades later

by Alan MozesWhat do race and early education have to do with dementia risk among seniors?Quite a bit, a new study suggests.Researchers spent decades tracking the onset ofdementiaamong nea

Neurology June 18,2024

'Aggressive' new advance directive would let dementia patients refuse food

by Jonel Aleccia, Kaiser Health NewsCredit: CC0 Public DomainTreading into ethically and legally uncertain territory, a New York end-of-life agency has approved a new document that lets people stipula

Neurology June 18,2024

'Aggressive' new advance directive would let dementia patients refuse food

by Jonel Aleccia, Kaiser Health NewsCredit: CC0 Public DomainTreading into ethically and legally uncertain territory, a New York end-of-life agency has approved a new document that lets people stipula

Neurology June 18,2024

Tau-based biomarker tracks Alzheimer's progression

by Washington University School of MedicineKanta Horie, PhD, works with a mass spectrometer that he uses to measure protein levels in cerebrospinal fluid samples. Horie and colleagues at Washingt

Neurology June 18,2024

Tau-based biomarker tracks Alzheimer's progression

by Washington University School of MedicineKanta Horie, PhD, works with a mass spectrometer that he uses to measure protein levels in cerebrospinal fluid samples. Horie and colleagues at Washingt

Neurology June 18,2024

Blood-based biomarkers for Alzheimer's disease could greatly simplify diagnosis and reduce costs

by Hôpitaux Universitaires de GenèveProportion of traditional exams that could be saved by using plasma biomarkers with 95%-sensitivity or 95%-specificity cut-offs. Values indicate the proportion of s

Neurology June 18,2024

Blood-based biomarkers for Alzheimer's disease could greatly simplify diagnosis and reduce costs

by Hôpitaux Universitaires de GenèveProportion of traditional exams that could be saved by using plasma biomarkers with 95%-sensitivity or 95%-specificity cut-offs. Values indicate the proportion of s

Neurology June 18,2024