Researchers determine timing is key for type 2 diabetes drug performance

by Rhiannon Koch,University of AdelaideStudy protocol. Credit:Diabetologia(2024). DOI: 10.1007/s00125-024-06131-6Researchers from the University of Adelaide could be closer to discov

Diabetes & Endocrinology June 18,2024 8

Researchers determine timing is key for type 2 diabetes drug performance

by Rhiannon Koch,University of AdelaideStudy protocol. Credit:Diabetologia(2024). DOI: 10.1007/s00125-024-06131-6Researchers from the University of Adelaide could be closer to discov

Diabetes & Endocrinology June 18,2024 8

Greater reduction seen in mortality with bariatric surgery than GLP-1 RAs

by Elana GotkineBariatric metabolic surgery (BMS) is associated with a greater reduction in mortality than glucagon-like peptide-1 receptor agonist (GLP-1 RA) treatment among adults with a diabetes du

Diabetes & Endocrinology June 18,2024 8

Greater reduction seen in mortality with bariatric surgery than GLP-1 RAs

by Elana GotkineBariatric metabolic surgery (BMS) is associated with a greater reduction in mortality than glucagon-like peptide-1 receptor agonist (GLP-1 RA) treatment among adults with a diabetes du

Diabetes & Endocrinology June 18,2024 8

Learning and memory problems in Down syndrome linked to alterations in genome's 'dark matter'

by Center for Genomic RegulationThe activity of Snhg11 (red) pictured in the dentate gyrus region of the hippocampus in mice. Credit: Cesar Sierra/Centro de Regulación Genómica (CRG)Researchers a

Psychiatry June 18,2024 4

Learning and memory problems in Down syndrome linked to alterations in genome's 'dark matter'

by Center for Genomic RegulationThe activity of Snhg11 (red) pictured in the dentate gyrus region of the hippocampus in mice. Credit: Cesar Sierra/Centro de Regulación Genómica (CRG)Researchers a

Psychiatry June 18,2024 4

Mouse study finds aging sperm affects microRNA, increasing the risk of neurodevelopmental disorders

by Tohoku UniversityVenn diagram showing the number of miRNAs expressed in sperm samples from mice aged 3 M, 12 M and 20 M. A total of 447 miRNAs were expressed, and about half of them are common

Reproduction June 18,2024 8

Mouse study finds aging sperm affects microRNA, increasing the risk of neurodevelopmental disorders

by Tohoku UniversityVenn diagram showing the number of miRNAs expressed in sperm samples from mice aged 3 M, 12 M and 20 M. A total of 447 miRNAs were expressed, and about half of them are common

Reproduction June 18,2024 8

Team explores role of 'stimulator of interferon genes' in body's innate immune system

by Tokai National Higher Education and Research SystemA graphical illustration of cholesterol- and palmitoylation-dependent STING clustering at the TGN. Credit: Institute for Glyco-core ResearchWhen p

Neurology June 18,2024 8

Team explores role of 'stimulator of interferon genes' in body's innate immune system

by Tokai National Higher Education and Research SystemA graphical illustration of cholesterol- and palmitoylation-dependent STING clustering at the TGN. Credit: Institute for Glyco-core ResearchWhen p

Neurology June 18,2024 8

Research team discovers genetic cause of low birth weight among children conceived after fertility treatment

by Université libre de BruxellesLower birthweight spontaneously conceived individuals and ART that are exposed to Vitrolife culture medium have higher incidence of non-synonymous and rRNA variant

Obstetrics & Gynecology June 18,2024 5

Research team discovers genetic cause of low birth weight among children conceived after fertility treatment

by Université libre de BruxellesLower birthweight spontaneously conceived individuals and ART that are exposed to Vitrolife culture medium have higher incidence of non-synonymous and rRNA variant

Obstetrics & Gynecology June 18,2024 5

Exploring complement system response to adeno-associated virus vector gene therapy

by Kathryn Ryan,Mary Ann Liebert, IncCredit: CC0 Public DomainRecent clinical trials utilizing high doses of adeno-associated virus (AAV) vectors have highlighted a new challenge to AAV gene tra

Medical research June 18,2024 5

Exploring complement system response to adeno-associated virus vector gene therapy

by Kathryn Ryan,Mary Ann Liebert, IncCredit: CC0 Public DomainRecent clinical trials utilizing high doses of adeno-associated virus (AAV) vectors have highlighted a new challenge to AAV gene tra

Medical research June 18,2024 5

Could a computer diagnose Alzheimer's disease and dementia?

by Gina Mantica,Boston UniversityCredit: Pixabay/CC0 Public DomainIt takes a lot of time—and money—to diagnose Alzheimer's disease. After running lengthy in-person neuropsychological exams,

Neurology June 18,2024 4

Could a computer diagnose Alzheimer's disease and dementia?

by Gina Mantica,Boston UniversityCredit: Pixabay/CC0 Public DomainIt takes a lot of time—and money—to diagnose Alzheimer's disease. After running lengthy in-person neuropsychological exams,

Neurology June 18,2024 4

Computer simulations explore how Alzheimer's disease starts

by Rice UniversityA team of Rice University researchers built computer simulations of amyloid beta proteins to see what their energy landscapes reveal about the formation of plaques in patients w

Neurology June 18,2024 6

Computer simulations explore how Alzheimer's disease starts

by Rice UniversityA team of Rice University researchers built computer simulations of amyloid beta proteins to see what their energy landscapes reveal about the formation of plaques in patients w

Neurology June 18,2024 6

'Viral relicts' in the genome could fuel neurodegeneration

by Marcus Neitzert, Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)Different HERV glycoproteins increase intercellular protein aggregate spreading.aExperimental workflow.

Neurology June 18,2024 6

'Viral relicts' in the genome could fuel neurodegeneration

by Marcus Neitzert, Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)Different HERV glycoproteins increase intercellular protein aggregate spreading.aExperimental workflow.

Neurology June 18,2024 6