Trials and tribulations of cell therapy for heart failure, an update on ongoing trials

by Jeff Hansen,University of Alabama at BirminghamJianyi "Jay" Zhang. Credit: UABPathways to new treatments for heart failure take time—as long as four decades for two now accepted the

Cardiology & Vascular surgery December 19,2024 0

Trials and tribulations of cell therapy for heart failure, an update on ongoing trials

by Jeff Hansen,University of Alabama at BirminghamJianyi "Jay" Zhang. Credit: UABPathways to new treatments for heart failure take time—as long as four decades for two now accepted the

Cardiology & Vascular surgery December 19,2024 0

Unexpected discovery revives abandoned breast cancer treatment

byLund UniversityMolecular analyses of IGFBP7 expression in I-SPY2 and SCAN-B. Credit:npj Precision Oncology(2024). DOI: 10.1038/s41698-024-00712-9A recent study led by Lund Universi

Drug Discovery December 19,2024 0

Unexpected discovery revives abandoned breast cancer treatment

byLund UniversityMolecular analyses of IGFBP7 expression in I-SPY2 and SCAN-B. Credit:npj Precision Oncology(2024). DOI: 10.1038/s41698-024-00712-9A recent study led by Lund Universi

Drug Discovery December 19,2024 0

Research team finds shortcomings in documentation of time-to-event analyses in systematic reviews

byInstitute for Quality and Efficiency in Health CareCredit: Pixabay/CC0 Public DomainSystematic reviews with time-to-event (TTE) analyses provide fundamental insights in many areas of research.

Drug Discovery December 19,2024 0

Research team finds shortcomings in documentation of time-to-event analyses in systematic reviews

byInstitute for Quality and Efficiency in Health CareCredit: Pixabay/CC0 Public DomainSystematic reviews with time-to-event (TTE) analyses provide fundamental insights in many areas of research.

Drug Discovery December 19,2024 0

Therapeutic technique shows potential for inhibiting the proliferation of SARS-CoV-2

byUniversity of BarcelonaSchematic representation of the SARS-CoV-2 genome and the location of the target regions for CC1 and CC3 PPRHs. Credit:Journal of Biological Chemistry(2024).

Infectious Diseases December 19,2024 0

Therapeutic technique shows potential for inhibiting the proliferation of SARS-CoV-2

byUniversity of BarcelonaSchematic representation of the SARS-CoV-2 genome and the location of the target regions for CC1 and CC3 PPRHs. Credit:Journal of Biological Chemistry(2024).

Infectious Diseases December 19,2024 0

New protocol targets fraud in rural online studies

by Elodie Smith,Cornell UniversityCredit: Pixabay/CC0 Public DomainA new protocol can detect and remove fake data created by bots and humans attempting to enroll in online research studies, in o

Drug Discovery December 19,2024 0

New protocol targets fraud in rural online studies

by Elodie Smith,Cornell UniversityCredit: Pixabay/CC0 Public DomainA new protocol can detect and remove fake data created by bots and humans attempting to enroll in online research studies, in o

Drug Discovery December 19,2024 0

Potential molecular therapy reverses placental development issues in mice

byFederation of American Societies for Experimental BiologyGraphic illustration of the mechanism by which METTL3-mediated m6A modification regulates FOSL1 expression to inhibit trophoblast invas

Medicial Breakthroughs December 19,2024 0

Potential molecular therapy reverses placental development issues in mice

byFederation of American Societies for Experimental BiologyGraphic illustration of the mechanism by which METTL3-mediated m6A modification regulates FOSL1 expression to inhibit trophoblast invas

Medicial Breakthroughs December 19,2024 0

Rules-based electronic triggers effectively ID missed opportunities in diagnosis

by Lori SolomonRules-based electronic triggers (e-triggers) are useful for post hoc detection of missed opportunities in diagnosis (MODs) in emergency department visits, according to a study published

Drug Discovery December 19,2024 0

Rules-based electronic triggers effectively ID missed opportunities in diagnosis

by Lori SolomonRules-based electronic triggers (e-triggers) are useful for post hoc detection of missed opportunities in diagnosis (MODs) in emergency department visits, according to a study published

Drug Discovery December 19,2024 0

Unique experiment sends T-cells into space

byKarolinska InstitutetRocket launch at Esrange 26 Nov. 2024. Credit: O. Jansson / S. KrämerOn 26 November, an experiment in a sounding rocket was launched at Esrange Space Center in Kiruna, Swe

Allergy&Clinical immunology December 18,2024 0

Unique experiment sends T-cells into space

byKarolinska InstitutetRocket launch at Esrange 26 Nov. 2024. Credit: O. Jansson / S. KrämerOn 26 November, an experiment in a sounding rocket was launched at Esrange Space Center in Kiruna, Swe

Allergy&Clinical immunology December 18,2024 0

First mouse strain susceptible to severe COVID-19 without the need for genetic modification identified

byJackson LaboratoryOut of these eight strains of mice, only the CAST mouse was susceptible to SARS-CoV-2, including beta, omicron and delta variants. The eight strains include A/J, B6J, CAST, 1

Public Health&Prevention December 18,2024 0

First mouse strain susceptible to severe COVID-19 without the need for genetic modification identified

byJackson LaboratoryOut of these eight strains of mice, only the CAST mouse was susceptible to SARS-CoV-2, including beta, omicron and delta variants. The eight strains include A/J, B6J, CAST, 1

Public Health&Prevention December 18,2024 0

About one-third eligible for weight loss drugs meet trial exclusion criteria

by Elana GotkineAbout one-third of U.S. adults without diabetes who are eligible for weight loss treatment with glucagon-like peptide 1 (GLP-1) receptor agonists and GLP-1/glucose-dependent insulinotr

Diabetes & Endocrinology December 18,2024 0

About one-third eligible for weight loss drugs meet trial exclusion criteria

by Elana GotkineAbout one-third of U.S. adults without diabetes who are eligible for weight loss treatment with glucagon-like peptide 1 (GLP-1) receptor agonists and GLP-1/glucose-dependent insulinotr

Diabetes & Endocrinology December 18,2024 0