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Science-2024 Breakthrough of the Year:The long shot

Science-2024 Breakthrough of the Year:The long shot

An innovative injectable HIV drug, lenacapavir, has shown significant effectiveness in preventing infections, offering a promising new breakthrough in the fight against the virus.

Science-2024 Breakthrough of the Year:The long shot

An innovative injectable HIV drug, lenacapavir, has shown significant effectiveness in preventing infections, offering a promising new breakthrough in the fight against the virus.
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Cell-based immunotherapy shows promise in early clinical trial for breast cancer

Cell-based immunotherapy shows promise in early clinical trial for breast cancer

byKent State UniversityBreast imaging of one trial patient before (left image) and after (right image) six weeks of experimental immunotherapy. Note diminution of area of disease (dense white ar

Cell-based immunotherapy shows promise in early clinical trial for breast cancer

byKent State UniversityBreast imaging of one trial patient before (left image) and after (right image) six weeks of experimental immunotherapy. Note diminution of area of disease (dense white ar
New toolkit to support the collection of cancer-patient-reported outcome measures

New toolkit to support the collection of cancer-patient-reported outcome measures

byUniversity of Strathclyde, GlasgowCredit: Pixabay/CC0 Public DomainA new Scotland-wide toolkit is supporting the collection of patient-reported outcome measures (PROMs) to understand the impac

New toolkit to support the collection of cancer-patient-reported outcome measures

byUniversity of Strathclyde, GlasgowCredit: Pixabay/CC0 Public DomainA new Scotland-wide toolkit is supporting the collection of patient-reported outcome measures (PROMs) to understand the impac
Enzyme identified as new therapeutic target for 'cold' tumors

Enzyme identified as new therapeutic target for 'cold' tumors

by Rebecca Dzombak,University of MichiganCredit: Pixabay/CC0 Public DomainA study from the University of Michigan Health Rogel Cancer Center may have—at last—cracked the cold case of immunothera

Enzyme identified as new therapeutic target for 'cold' tumors

by Rebecca Dzombak,University of MichiganCredit: Pixabay/CC0 Public DomainA study from the University of Michigan Health Rogel Cancer Center may have—at last—cracked the cold case of immunothera
Unraveling the viral puzzle of why humans are susceptible to hepatitis B virus, but monkeys are not

Unraveling the viral puzzle of why humans are susceptible to hepatitis B virus, but monkeys are not

byTokyo University of ScienceStructural comparison of mNTCP and hNTCP. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-53533-6Hepatitis B virus (HBV) infection is a leadi

Unraveling the viral puzzle of why humans are susceptible to hepatitis B virus, but monkeys are not

byTokyo University of ScienceStructural comparison of mNTCP and hNTCP. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-53533-6Hepatitis B virus (HBV) infection is a leadi
Scientists identify brain cell type as master controller of urination

Scientists identify brain cell type as master controller of urination

by Emily Packer, George Litchfield,eLifePMCESR1+cells tightly correlate with successful voiding. Credit:eLife(2024). DOI: 10.7554/eLife.103224.1Researchers have identified a su

Scientists identify brain cell type as master controller of urination

by Emily Packer, George Litchfield,eLifePMCESR1+cells tightly correlate with successful voiding. Credit:eLife(2024). DOI: 10.7554/eLife.103224.1Researchers have identified a su
Scientists discover new receptor for nerve growth factor—a promising target for treating pain

Scientists discover new receptor for nerve growth factor—a promising target for treating pain

byNew York UniversityNerve growth factor receptor TrkA (in green) and co-receptor NRP1 (in purple) are coexpressed in the same nerve cells in mice. Credit: Bunnett LabResearchers at the NYU Pain

Scientists discover new receptor for nerve growth factor—a promising target for treating pain

byNew York UniversityNerve growth factor receptor TrkA (in green) and co-receptor NRP1 (in purple) are coexpressed in the same nerve cells in mice. Credit: Bunnett LabResearchers at the NYU Pain
Discontinuing cholinesterase when starting memantine not tied to institutionalization care

Discontinuing cholinesterase when starting memantine not tied to institutionalization care

by Lori SolomonDiscontinuing cholinesterase inhibitors upon memantine initiation is not associated with an increased risk for long-term care institutionalization among older adults with dementia, acco

Discontinuing cholinesterase when starting memantine not tied to institutionalization care

by Lori SolomonDiscontinuing cholinesterase inhibitors upon memantine initiation is not associated with an increased risk for long-term care institutionalization among older adults with dementia, acco
Gut microbiota: A consensus paper to regulate the 'wild west' of diagnostic tests

Gut microbiota: A consensus paper to regulate the 'wild west' of diagnostic tests

byCatholic University of the Sacred HeartCredit: CC0 Public DomainThe gut microbiota might perhaps one day become a routine tool for the early diagnosis of many diseases and to guide treatment,

Gut microbiota: A consensus paper to regulate the 'wild west' of diagnostic tests

byCatholic University of the Sacred HeartCredit: CC0 Public DomainThe gut microbiota might perhaps one day become a routine tool for the early diagnosis of many diseases and to guide treatment,
New method of drug discovery and development offers better understanding of how drugs work

New method of drug discovery and development offers better understanding of how drugs work

byKarolinska InstitutetCeTEAM is predicated on stability-dependent biosensors to measure drug binding. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-54415-7According to

New method of drug discovery and development offers better understanding of how drugs work

byKarolinska InstitutetCeTEAM is predicated on stability-dependent biosensors to measure drug binding. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-54415-7According to
Mouse study captures aging process at the cellular level

Mouse study captures aging process at the cellular level

by Holly Hartigan,Cornell UniversityDetermining the cell type composition in each day post injury. Credit:Nature Aging(2024). DOI: 10.1038/s43587-024-00756-3As muscles age, their cel

Mouse study captures aging process at the cellular level

by Holly Hartigan,Cornell UniversityDetermining the cell type composition in each day post injury. Credit:Nature Aging(2024). DOI: 10.1038/s43587-024-00756-3As muscles age, their cel
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