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Pelage Pharmaceuticals Advances Hair Loss Treatment with Phase 2 Study and $14M Funding

Pelage Pharmaceuticals Advances Hair Loss Treatment with Phase 2 Study and $14M Funding

Pelage Pharmaceuticals has commenced dosing the first patients in its Phase 2a clinical trial for PP405, a novel topical treatment designed to reactivate dormant hair follicle stem cells.
Dermatology August 14,2024
Pelage Pharmaceuticals Advances Hair Loss Treatment with Phase 2 Study and $14M Funding

Pelage Pharmaceuticals Advances Hair Loss Treatment with Phase 2 Study and $14M Funding

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Blood Types: What Letters, Positive, and Negative Signs Mean

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A chemistry pioneer works to improve a flawed test for a common cancer

A chemistry pioneer works to improve a flawed test for a common cancer

by Clare Milliken,Northwestern UniversityKelleher says top-down proteomics provides a more comprehensiveunderstanding of human proteins than bottom-up proteomics, which is both imprecise a
Oncology May 23,2024
A chemistry pioneer works to improve a flawed test for a common cancer

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by Clare Milliken,Northwestern UniversityKelleher says top-down proteomics provides a more comprehensiveunderstanding of human proteins than bottom-up proteomics, which is both imprecise a
Oncology May 23,2024
Tracking the epigenetic evolution of a cancer, cell by cell

Tracking the epigenetic evolution of a cancer, cell by cell

by Weill Cornell Medical CollegeDr. Dan Landau. Credit: Rene PerezA powerful new set of scientific tools developed by Weill Cornell Medicine and New York Genome Center (NYGC) researchers enables
Oncology May 23,2024
Tracking the epigenetic evolution of a cancer, cell by cell

Tracking the epigenetic evolution of a cancer, cell by cell

by Weill Cornell Medical CollegeDr. Dan Landau. Credit: Rene PerezA powerful new set of scientific tools developed by Weill Cornell Medicine and New York Genome Center (NYGC) researchers enables
Oncology May 23,2024
Front-line osimertinib improves overall survival in EGFR-mutation positive NSCLC

Front-line osimertinib improves overall survival in EGFR-mutation positive NSCLC

by European Society for Medical OncologyCredit: © European Society for Medical OncologyFirst-line osimertinib significantly lengthens overall survival compared to older generation EGFR-TKIs in pa
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Front-line osimertinib improves overall survival in EGFR-mutation positive NSCLC

Front-line osimertinib improves overall survival in EGFR-mutation positive NSCLC

by European Society for Medical OncologyCredit: © European Society for Medical OncologyFirst-line osimertinib significantly lengthens overall survival compared to older generation EGFR-TKIs in pa
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Drug combo heralds major shift in chronic lymphocytic leukemia treatment

Drug combo heralds major shift in chronic lymphocytic leukemia treatment

by Stanford University Medical CenterCancer cells. Credit: Dr. Cecil Fox, National Cancer InstituteA combination of two drugs keeps patients with chronic lymphocytic leukemia disease-free and ali
Oncology May 23,2024
Drug combo heralds major shift in chronic lymphocytic leukemia treatment

Drug combo heralds major shift in chronic lymphocytic leukemia treatment

by Stanford University Medical CenterCancer cells. Credit: Dr. Cecil Fox, National Cancer InstituteA combination of two drugs keeps patients with chronic lymphocytic leukemia disease-free and ali
Oncology May 23,2024
Two for the price of one: Mechanistic insights lead to drug repositioning

Two for the price of one: Mechanistic insights lead to drug repositioning

by University of TsukubaMolecular mechanism at a glance. SFN binds with SKP1 to sequester it in cytoplasm,resulting in the obstruction of SCFFBW7 598 complex formation. Oncoproteins including cyc
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Two for the price of one: Mechanistic insights lead to drug repositioning

Two for the price of one: Mechanistic insights lead to drug repositioning

by University of TsukubaMolecular mechanism at a glance. SFN binds with SKP1 to sequester it in cytoplasm,resulting in the obstruction of SCFFBW7 598 complex formation. Oncoproteins including cyc
Oncology May 23,2024
Drug combo slows progression in advanced breast cancer

Drug combo slows progression in advanced breast cancer

(HealthDay)—Treatment with a combination of alpelisib and fulvestrant prolongs progression-free survival among patients withPIK3CA-mutated, hormone receptor (HR)-positive, human epidermal growth
Oncology May 23,2024
Drug combo slows progression in advanced breast cancer

Drug combo slows progression in advanced breast cancer

(HealthDay)—Treatment with a combination of alpelisib and fulvestrant prolongs progression-free survival among patients withPIK3CA-mutated, hormone receptor (HR)-positive, human epidermal growth
Oncology May 23,2024
National cancer control efforts should address the system, not its individual parts, says new report

National cancer control efforts should address the system, not its individual parts, says new report

by National Academy of SciencesCredit: CC0 Public DomainCurrent cancer control efforts in the United States typically are fragmented and uncoordinated, but taking a systems approach to establish
Oncology May 23,2024
National cancer control efforts should address the system, not its individual parts, says new report

National cancer control efforts should address the system, not its individual parts, says new report

by National Academy of SciencesCredit: CC0 Public DomainCurrent cancer control efforts in the United States typically are fragmented and uncoordinated, but taking a systems approach to establish
Oncology May 23,2024
Promise of liquid biopsy in cancer biomarker detection and prenatal screening

Promise of liquid biopsy in cancer biomarker detection and prenatal screening

by Mary Ann Liebert, IncCredit: Mary Ann Liebert, Inc., publishersThe promise and challenges of liquid biopsy, an emerging, noninvasive method for targeted disease diagnosis and detection of canc
Oncology May 23,2024
Promise of liquid biopsy in cancer biomarker detection and prenatal screening

Promise of liquid biopsy in cancer biomarker detection and prenatal screening

by Mary Ann Liebert, IncCredit: Mary Ann Liebert, Inc., publishersThe promise and challenges of liquid biopsy, an emerging, noninvasive method for targeted disease diagnosis and detection of canc
Oncology May 23,2024
Drug combination shows promise in preclinical models of triple negative breast cancer

Drug combination shows promise in preclinical models of triple negative breast cancer

by Alhaji Janneh,Medical University of South CarolinaYueying Liu and Dr. Antonio Giordano study PLK1 inhibitors, traffic light-like signals that stop the uncontrolled growth of breast cancer cel
Oncology May 23,2024
Drug combination shows promise in preclinical models of triple negative breast cancer

Drug combination shows promise in preclinical models of triple negative breast cancer

by Alhaji Janneh,Medical University of South CarolinaYueying Liu and Dr. Antonio Giordano study PLK1 inhibitors, traffic light-like signals that stop the uncontrolled growth of breast cancer cel
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Global study predicts more than 50 percent rise in chemotherapy demand by 2040

Global study predicts more than 50 percent rise in chemotherapy demand by 2040

byLancetCredit: CC0 Public DomainTo deliver optimal treatment by 2040, a significant expansion of the chemotherapy workforce is needed.Between 2018 and 2040, the number of patients requiri
Oncology May 23,2024
Global study predicts more than 50 percent rise in chemotherapy demand by 2040

Global study predicts more than 50 percent rise in chemotherapy demand by 2040

byLancetCredit: CC0 Public DomainTo deliver optimal treatment by 2040, a significant expansion of the chemotherapy workforce is needed.Between 2018 and 2040, the number of patients requiri
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