Mosaics of predisposition found to cause skin disease

by Kobe UniversityTo develop porokeratosis, people need two damaged copies of the gene, "two hits." One they acquire either from their parents (left) or through epigenetic silencing early in

Dermatology May 14,2024

Mosaics of predisposition found to cause skin disease

by Kobe UniversityTo develop porokeratosis, people need two damaged copies of the gene, "two hits." One they acquire either from their parents (left) or through epigenetic silencing early in

Dermatology May 14,2024

Environment may influence metacognitive abilities more than genetics

by Cell PressGraphical abstract Credit: Cell Reports (2024). DOI: 10.1016/j.celrep.2024.114060Twin studies have proven invaluable for teasing out the effects of both genetics and the environment on hu

Public Health & Prevention May 14,2024

Environment may influence metacognitive abilities more than genetics

by Cell PressGraphical abstract Credit: Cell Reports (2024). DOI: 10.1016/j.celrep.2024.114060Twin studies have proven invaluable for teasing out the effects of both genetics and the environment on hu

Public Health & Prevention May 14,2024

New gene therapy for metachromatic leukodystrophy proves effective in mice

by Marie Simon, Paris Brain InstituteGraphical abstract. Credit: Molecular Therapy - Methods & Clinical Development (2024). DOI: 10.1016/j.omtm.2024.101248Metachromatic leukodystrophy is a rare ge

Neurology May 14,2024

New gene therapy for metachromatic leukodystrophy proves effective in mice

by Marie Simon, Paris Brain InstituteGraphical abstract. Credit: Molecular Therapy - Methods & Clinical Development (2024). DOI: 10.1016/j.omtm.2024.101248Metachromatic leukodystrophy is a rare ge

Neurology May 14,2024

Potential modifier gene identified as cause of ciliary pathology in retinitis pigmentosa patient

by University of BarcelonaIn silico studies of c.920C>A;p.(Thr307Lys) variant in the RPGR gene. Credit: Cells (2024). DOI: 10.3390/cells13060524Ciliopathies are rare diseases in which the formation

Ophthalmology May 14,2024

Potential modifier gene identified as cause of ciliary pathology in retinitis pigmentosa patient

by University of BarcelonaIn silico studies of c.920C>A;p.(Thr307Lys) variant in the RPGR gene. Credit: Cells (2024). DOI: 10.3390/cells13060524Ciliopathies are rare diseases in which the formation

Ophthalmology May 14,2024

Researchers identify abrupt epigenetic aging of the colon

by Leibniz Institute on Aging – Fritz Lipmann Institute (FLI)Pie charts with the cytosine proportion in the particular cluster to all aDMR cytosines; DNA methylation trajectories during aging as Z-sco

Gastroenterology May 14,2024

Researchers identify abrupt epigenetic aging of the colon

by Leibniz Institute on Aging – Fritz Lipmann Institute (FLI)Pie charts with the cytosine proportion in the particular cluster to all aDMR cytosines; DNA methylation trajectories during aging as Z-sco

Gastroenterology May 14,2024

'Miracle' weight-loss drugs could have reduced health disparities: Instead they got worse

by Karen Kaplan, Los Angeles TimesCredit: Pixabay/CC0 Public DomainThe American Heart Association calls them "game changers."Oprah Winfrey says they're "a gift."Science magazin

Diabetes & Endocrinology May 14,2024

'Miracle' weight-loss drugs could have reduced health disparities: Instead they got worse

by Karen Kaplan, Los Angeles TimesCredit: Pixabay/CC0 Public DomainThe American Heart Association calls them "game changers."Oprah Winfrey says they're "a gift."Science magazin

Diabetes & Endocrinology May 14,2024

Shoe technology helps reduce risk of diabetic foot ulcers

by Katherine Egan Bennett, University of Texas at ArlingtonAbout one-third of people with diabetes develop foot ulcers during their lifetime. In the U.S., more than 160,000 lower extremity amputations

Diabetes & Endocrinology May 14,2024

Shoe technology helps reduce risk of diabetic foot ulcers

by Katherine Egan Bennett, University of Texas at ArlingtonAbout one-third of people with diabetes develop foot ulcers during their lifetime. In the U.S., more than 160,000 lower extremity amputations

Diabetes & Endocrinology May 14,2024

Three ways to improve diabetes care through telehealth

by UC DavisSenior author Stephanie Crossen uses telehealth. Credit: UC RegentsGrocery stores, airports and beaches aren't great places to have telehealth visits with your endocrinologist. But home

Diabetes & Endocrinology May 14,2024

Three ways to improve diabetes care through telehealth

by UC DavisSenior author Stephanie Crossen uses telehealth. Credit: UC RegentsGrocery stores, airports and beaches aren't great places to have telehealth visits with your endocrinologist. But home

Diabetes & Endocrinology May 14,2024

New findings on pancreatic anatomy may affect diabetes research and treatment

by Claes Björnberg, Umea UniversityGeneration of volumetric and 3D-spatial data sets of the complete β-cell distribution across the human pancreas. Credit: Nature Communications (2024). DOI: 10.1038/s

Diabetes & Endocrinology May 14,2024

New findings on pancreatic anatomy may affect diabetes research and treatment

by Claes Björnberg, Umea UniversityGeneration of volumetric and 3D-spatial data sets of the complete β-cell distribution across the human pancreas. Credit: Nature Communications (2024). DOI: 10.1038/s

Diabetes & Endocrinology May 14,2024

Type 2 diabetes is not one-size-fits-all: Subtypes affect complications and treatment options

by Lili Grieco-St-Pierre and Jennifer Bruin, The ConversationCredit: CC0 Public DomainYou may have heard of Ozempic, the "miracle drug" for weight loss, but did you know that it was actually

Diabetes & Endocrinology May 14,2024

Type 2 diabetes is not one-size-fits-all: Subtypes affect complications and treatment options

by Lili Grieco-St-Pierre and Jennifer Bruin, The ConversationCredit: CC0 Public DomainYou may have heard of Ozempic, the "miracle drug" for weight loss, but did you know that it was actually

Diabetes & Endocrinology May 14,2024