DNA treatment could delay paralysis that strikes nearly all patients with ALS

byUniversity of California - San DiegoAn illustration of the connections between muscle fibers and a motor neuron, the latter of which relies on crucial proteins to create and send signals to th

Neurology April 09,2024

DNA treatment could delay paralysis that strikes nearly all patients with ALS

byUniversity of California - San DiegoAn illustration of the connections between muscle fibers and a motor neuron, the latter of which relies on crucial proteins to create and send signals to th

Neurology April 09,2024

Immune genes are altered in Alzheimer's patients' blood

byNorthwestern UniversityCredit:Neuron(2024). DOI: 10.1016/j.neuron.2024.01.013A new Northwestern Medicine study has found the immune system in the blood of Alzheimer's patients

Neurology April 09,2024

Immune genes are altered in Alzheimer's patients' blood

byNorthwestern UniversityCredit:Neuron(2024). DOI: 10.1016/j.neuron.2024.01.013A new Northwestern Medicine study has found the immune system in the blood of Alzheimer's patients

Neurology April 09,2024

New insights into the protein-mediated motor neuron loss in amyotrophic lateral sclerosis

by Niigata UniversityUsing novel mouse ALS models, researchers discovered that the pathogenic TDP-43 exhibits distinct propagation patterns in the corticospinal pathway and spinal circuits, providing

Neurology April 09,2024

New insights into the protein-mediated motor neuron loss in amyotrophic lateral sclerosis

by Niigata UniversityUsing novel mouse ALS models, researchers discovered that the pathogenic TDP-43 exhibits distinct propagation patterns in the corticospinal pathway and spinal circuits, providing

Neurology April 09,2024

From pills to pulses: Electrifying medicine using the peripheral nervous system

byIMECBio-electronic medicine is a new form of therapy that uses electrical pulses to modulate nerve activity. The small implant delivering the pulses sits in the body, a wearable device deliver

Neurology April 09,2024

From pills to pulses: Electrifying medicine using the peripheral nervous system

byIMECBio-electronic medicine is a new form of therapy that uses electrical pulses to modulate nerve activity. The small implant delivering the pulses sits in the body, a wearable device deliver

Neurology April 09,2024

Clues to COVID-19 complications come from NET-like inflammatory response

by University of Utah Health SciencesUniversity of Utah Health critical care specialist Elizabeth Middleton, MD, treats patients with COVID-19 in the intensive care unit. A research team includin

Public Health & Prevention April 09,2024

Clues to COVID-19 complications come from NET-like inflammatory response

by University of Utah Health SciencesUniversity of Utah Health critical care specialist Elizabeth Middleton, MD, treats patients with COVID-19 in the intensive care unit. A research team includin

Public Health & Prevention April 09,2024

CAR-T immunotherapy could be improved to kill solid tumors

by Thomas Jefferson UniversityCancer cell during cell division. Credit: National Institutes of HealthImmunotherapy, which harnesses the power of the body's immune system to fight disease, is

Oncology April 09,2024

CAR-T immunotherapy could be improved to kill solid tumors

by Thomas Jefferson UniversityCancer cell during cell division. Credit: National Institutes of HealthImmunotherapy, which harnesses the power of the body's immune system to fight disease, is

Oncology April 09,2024

CAR T cell therapy: On the cusp of 'an immunotherapy revolution'?

by Delthia Ricks , Medical XpressCancer cell during cell division. Credit: National Institutes of HealthA deeper understanding of the immune system's role in controlling cancer has helped drive &q

Oncology April 09,2024

CAR T cell therapy: On the cusp of 'an immunotherapy revolution'?

by Delthia Ricks , Medical XpressCancer cell during cell division. Credit: National Institutes of HealthA deeper understanding of the immune system's role in controlling cancer has helped drive &q

Oncology April 09,2024

CAR T-cell immunotherapy rids woman of tough-to-treat lupus

by Amy Norton(HealthDay)—In a first, researchers have used genetically tweaked immune system cells to send a woman's severe lupus into remission.The treatment—called CAR T-cell therapy—is already

Immunology & Rheumatology April 09,2024

CAR T-cell immunotherapy rids woman of tough-to-treat lupus

by Amy Norton(HealthDay)—In a first, researchers have used genetically tweaked immune system cells to send a woman's severe lupus into remission.The treatment—called CAR T-cell therapy—is already

Immunology & Rheumatology April 09,2024

CAR T cell immunotherapy for solid tumors? First, you have to break the cancers' sugar shield

by Delthia Ricks , Medical XpressModeling of the impact of tumor N-glycans on the targeting by CAR T cells. Left, the N-glycan decoration of tumors 1) repels CAR T cells by impeding immunological syna

Oncology April 09,2024

CAR T cell immunotherapy for solid tumors? First, you have to break the cancers' sugar shield

by Delthia Ricks , Medical XpressModeling of the impact of tumor N-glycans on the targeting by CAR T cells. Left, the N-glycan decoration of tumors 1) repels CAR T cells by impeding immunological syna

Oncology April 09,2024

CAR T cell therapies may lead to reactivation of childhood viral infections

by Justin Jackson , Medical XpressPetabase-scale analysis of viral nucleic acids reveals that HHV-6 is reactivated in human T cells. a, Schematic of life cycles of endogenous human viruses. Viruses ca

Immunology & Rheumatology April 09,2024

CAR T cell therapies may lead to reactivation of childhood viral infections

by Justin Jackson , Medical XpressPetabase-scale analysis of viral nucleic acids reveals that HHV-6 is reactivated in human T cells. a, Schematic of life cycles of endogenous human viruses. Viruses ca

Immunology & Rheumatology April 09,2024