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Pelage Pharmaceuticals Advances Hair Loss Treatment with Phase 2 Study and $14M Funding

Pelage Pharmaceuticals Advances Hair Loss Treatment with Phase 2 Study and $14M Funding

Pelage Pharmaceuticals has commenced dosing the first patients in its Phase 2a clinical trial for PP405, a novel topical treatment designed to reactivate dormant hair follicle stem cells.
Dermatology August 14,2024
Pelage Pharmaceuticals Advances Hair Loss Treatment with Phase 2 Study and $14M Funding

Pelage Pharmaceuticals Advances Hair Loss Treatment with Phase 2 Study and $14M Funding

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Blood Types: What Letters, Positive, and Negative Signs Mean

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Blood Types: What Letters, Positive, and Negative Signs Mean

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Study reveals the role of the protein Kdm1a in maintaining neuronal identity

Study reveals the role of the protein Kdm1a in maintaining neuronal identity

by Miguel Hernandez University of ElcheNeurons from the brain of an adult mouse in which chromatin (in blue), the nuclear envelope (in green), and silenced regions of chromatin (in red) are label
Genetics March 20,2024
Study reveals the role of the protein Kdm1a in maintaining neuronal identity

Study reveals the role of the protein Kdm1a in maintaining neuronal identity

by Miguel Hernandez University of ElcheNeurons from the brain of an adult mouse in which chromatin (in blue), the nuclear envelope (in green), and silenced regions of chromatin (in red) are label
Genetics March 20,2024
Novel DNA shift discovery may benefit severe immune conditions

Novel DNA shift discovery may benefit severe immune conditions

by Felicia Spencer,Virginia TechCredit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113894Discovery of a DNA shift in the innate immune memory of cells may aid in the fight against
Genetics March 20,2024
Novel DNA shift discovery may benefit severe immune conditions

Novel DNA shift discovery may benefit severe immune conditions

by Felicia Spencer,Virginia TechCredit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113894Discovery of a DNA shift in the innate immune memory of cells may aid in the fight against
Genetics March 20,2024
Study links key gene to protection from severe illness and death from COVID infections in men under age 75

Study links key gene to protection from severe illness and death from COVID infections in men under age 75

by David March,NYU Langone HealthGraphical Abstract. Credit:The Journal of Infectious Diseases(2024). DOI: 10.1093/infdis/jiae031A certain variant of a key anti-inflammatory gene pro
Public Health & Prevention March 20,2024
Study links key gene to protection from severe illness and death from COVID infections in men under age 75

Study links key gene to protection from severe illness and death from COVID infections in men under age 75

by David March,NYU Langone HealthGraphical Abstract. Credit:The Journal of Infectious Diseases(2024). DOI: 10.1093/infdis/jiae031A certain variant of a key anti-inflammatory gene pro
Public Health & Prevention March 20,2024
Blood mutations increase risk for acute kidney injury, says study

Blood mutations increase risk for acute kidney injury, says study

by Vanderbilt University Medical CenterTet2-deficient macrophages are hyperinflammatory in early ischemic kidney injury. Credit:Nature Medicine(2024). DOI: 10.1038/s41591-024-02854-6A
Nephrology & Urology March 20,2024
Blood mutations increase risk for acute kidney injury, says study

Blood mutations increase risk for acute kidney injury, says study

by Vanderbilt University Medical CenterTet2-deficient macrophages are hyperinflammatory in early ischemic kidney injury. Credit:Nature Medicine(2024). DOI: 10.1038/s41591-024-02854-6A
Nephrology & Urology March 20,2024
Team performs the first gene therapy tests in a whole human liver

Team performs the first gene therapy tests in a whole human liver

by Children's Medical Research InstituteCredit: Pixabay/CC0 Public DomainIn a worldwide first-of-its-kind study published in the journalNature Communicationsthis week, a team of scient
Hepatobiliary&Pancreas Surgery March 20,2024
Team performs the first gene therapy tests in a whole human liver

Team performs the first gene therapy tests in a whole human liver

by Children's Medical Research InstituteCredit: Pixabay/CC0 Public DomainIn a worldwide first-of-its-kind study published in the journalNature Communicationsthis week, a team of scient
Hepatobiliary&Pancreas Surgery March 20,2024
Mutation provides insights into mechanisms of neurodegeneration in Parkinson's disease

Mutation provides insights into mechanisms of neurodegeneration in Parkinson's disease

by Olivia Dimmer,Northwestern UniversityVPS13C deficiency alters ER-lysosome and mitochondria-lysosome contact sites in iPSC-derived dopaminergic neurons. (A and B). Credit:Journal of Cell
Neurology March 20,2024
Mutation provides insights into mechanisms of neurodegeneration in Parkinson's disease

Mutation provides insights into mechanisms of neurodegeneration in Parkinson's disease

by Olivia Dimmer,Northwestern UniversityVPS13C deficiency alters ER-lysosome and mitochondria-lysosome contact sites in iPSC-derived dopaminergic neurons. (A and B). Credit:Journal of Cell
Neurology March 20,2024
Researchers identify mutation that alters Alzheimer's disease progression

Researchers identify mutation that alters Alzheimer's disease progression

by University of MalagaResearchers identify a mutation that alters Alzheimer's disease progression. The UMA coordinates this study, carried out by 100 multidisciplinary researchers from 50 di
Neurology March 20,2024
Researchers identify mutation that alters Alzheimer's disease progression

Researchers identify mutation that alters Alzheimer's disease progression

by University of MalagaResearchers identify a mutation that alters Alzheimer's disease progression. The UMA coordinates this study, carried out by 100 multidisciplinary researchers from 50 di
Neurology March 20,2024
In our cellular 'glue,' scientists find answers about heart attacks, strokes and more

In our cellular 'glue,' scientists find answers about heart attacks, strokes and more

by University of VirginiaAtherosclerosis is a condition affecting the cardiovascular system. If atherosclerosis occurs in the coronary arteries (which supply the heart) the result may be angina p
Cardiovascular Diseases March 20,2024
In our cellular 'glue,' scientists find answers about heart attacks, strokes and more

In our cellular 'glue,' scientists find answers about heart attacks, strokes and more

by University of VirginiaAtherosclerosis is a condition affecting the cardiovascular system. If atherosclerosis occurs in the coronary arteries (which supply the heart) the result may be angina p
Cardiovascular Diseases March 20,2024
FRYL gene variants linked to a new neurological disorder

FRYL gene variants linked to a new neurological disorder

by Texas Children's HospitalCredit: Unsplash/CC0 Public DomainA recent study from the lab of Dr. Hugo J. Bellen, distinguished service professor at Baylor College of Medicine and investigator
Neurology March 20,2024
FRYL gene variants linked to a new neurological disorder

FRYL gene variants linked to a new neurological disorder

by Texas Children's HospitalCredit: Unsplash/CC0 Public DomainA recent study from the lab of Dr. Hugo J. Bellen, distinguished service professor at Baylor College of Medicine and investigator
Neurology March 20,2024
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