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Pelage Pharmaceuticals Advances Hair Loss Treatment with Phase 2 Study and $14M Funding

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Pelage Pharmaceuticals has commenced dosing the first patients in its Phase 2a clinical trial for PP405, a novel topical treatment designed to reactivate dormant hair follicle stem cells.
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Pelage Pharmaceuticals Advances Hair Loss Treatment with Phase 2 Study and $14M Funding

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Pelage Pharmaceuticals has commenced dosing the first patients in its Phase 2a clinical trial for PP405, a novel topical treatment designed to reactivate dormant hair follicle stem cells.
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Blood Types: What Letters, Positive, and Negative Signs Mean

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SCO-101 Plus FOLFIRI Provides Survival Benefit in Metastatic Colorectal Cancer

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November 22, 2023Kristi RosaSCO-101 in combination with leucovorin, fluorouracil, and irinotecan (FOLFIRI) provided a clinically meaningful overall survival benefit in heavily pretreated patients with
World medicine November 23,2023
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November 22, 2023Kristi RosaSCO-101 in combination with leucovorin, fluorouracil, and irinotecan (FOLFIRI) provided a clinically meaningful overall survival benefit in heavily pretreated patients with
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Maintaining a healthy weight could reduce future gastrointestinal cancer risk

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Doctors have long stressed the importance of maintaining a healthy weight for improving overall health, but a large new study also suggests it could also reduce future gastrointestinal cancer (GI) ris
World medicine November 23,2023
Maintaining a healthy weight could reduce future gastrointestinal cancer risk

Maintaining a healthy weight could reduce future gastrointestinal cancer risk

Doctors have long stressed the importance of maintaining a healthy weight for improving overall health, but a large new study also suggests it could also reduce future gastrointestinal cancer (GI) ris
World medicine November 23,2023
RLY-4008 Shows Initial Activity With a Manageable Safety Profile in Cholangiocarcinoma

RLY-4008 Shows Initial Activity With a Manageable Safety Profile in Cholangiocarcinoma

August 31, 2023Kyle DohertyMitesh J. Borad, MD, highlights key additional findings from ReFocus and how RLY-4008 differs from currently available FGFR2 inhibitors.Mitesh J. Borad, MDThe first highly s
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RLY-4008 Shows Initial Activity With a Manageable Safety Profile in Cholangiocarcinoma

RLY-4008 Shows Initial Activity With a Manageable Safety Profile in Cholangiocarcinoma

August 31, 2023Kyle DohertyMitesh J. Borad, MD, highlights key additional findings from ReFocus and how RLY-4008 differs from currently available FGFR2 inhibitors.Mitesh J. Borad, MDThe first highly s
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Testing hundreds of existing therapeutics to fight blood cancer more effectively

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Multiple myeloma is a rare blood cancer caused by the uncontrolled multiplication of abnormal plasma cells. These plasma cells are a special type of white blood cells that play an important role in th
World medicine November 23,2023
Testing hundreds of existing therapeutics to fight blood cancer more effectively

Testing hundreds of existing therapeutics to fight blood cancer more effectively

Multiple myeloma is a rare blood cancer caused by the uncontrolled multiplication of abnormal plasma cells. These plasma cells are a special type of white blood cells that play an important role in th
World medicine November 23,2023
REGAL Trial Examining Galinpepimut-S in AML to Continue Without Modifications

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August 24, 2023Kristi RosaAn independent data monitoring committee has recommended that the phase 3 REGAL trial evaluating galinpepimut-S in patients with acute myeloid leukemia should continue withou
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REGAL Trial Examining Galinpepimut-S in AML to Continue Without Modifications

REGAL Trial Examining Galinpepimut-S in AML to Continue Without Modifications

August 24, 2023Kristi RosaAn independent data monitoring committee has recommended that the phase 3 REGAL trial evaluating galinpepimut-S in patients with acute myeloid leukemia should continue withou
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PROSPECT Trial Confirms Feasibility of De-escalation of Neoadjuvant Chemoradiation in Locally Advanced Rectal Cancer

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August 23, 2023Courtney FlahertyMichael Cecchini, MD, expands on key updates in gastrointestinal cancer from the 2023 ASCO Annual Meeting, including the clinical significance of findings from the PROS
World medicine November 23,2023
PROSPECT Trial Confirms Feasibility of De-escalation of Neoadjuvant Chemoradiation in Locally Advanced Rectal Cancer

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August 23, 2023Courtney FlahertyMichael Cecchini, MD, expands on key updates in gastrointestinal cancer from the 2023 ASCO Annual Meeting, including the clinical significance of findings from the PROS
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NVL-655 Elicits Preliminary Activity, Safety in Heavily Pretreated, ALK+ Advanced NSCLC

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October 13, 2023Ryan ScottTreatment with the novel, ALK-selective TKI NVL-655 generated responses and was well tolerated in heavily pretreated patients with ALK-positive, advanced non–small cell lung
World medicine November 23,2023
NVL-655 Elicits Preliminary Activity, Safety in Heavily Pretreated, ALK+ Advanced NSCLC

NVL-655 Elicits Preliminary Activity, Safety in Heavily Pretreated, ALK+ Advanced NSCLC

October 13, 2023Ryan ScottTreatment with the novel, ALK-selective TKI NVL-655 generated responses and was well tolerated in heavily pretreated patients with ALK-positive, advanced non–small cell lung
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Using engineered stem cells to treat ALS and retinitis pigmentosa

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Cedars-Sinai investigators are developing a novel way to treat amyotrophic lateral sclerosis (ALS) and retinitis pigmentosa using engineered stem cells that may eventually lead to personalized treatme
World medicine November 23,2023
Using engineered stem cells to treat ALS and retinitis pigmentosa

Using engineered stem cells to treat ALS and retinitis pigmentosa

Cedars-Sinai investigators are developing a novel way to treat amyotrophic lateral sclerosis (ALS) and retinitis pigmentosa using engineered stem cells that may eventually lead to personalized treatme
World medicine November 23,2023
NCCN Endorses Goserelin in Salivary Gland Tumors in New Head and Neck Cancers Guidelines

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November 13, 2023Kyle DohertyTerSera Therapeutics LLC announced that The National Comprehensive Cancer Network Head and Neck Cancers Panel recommended the GnRH agonist goserelin for patients with recu
World medicine November 23,2023
NCCN Endorses Goserelin in Salivary Gland Tumors in New Head and Neck Cancers Guidelines

NCCN Endorses Goserelin in Salivary Gland Tumors in New Head and Neck Cancers Guidelines

November 13, 2023Kyle DohertyTerSera Therapeutics LLC announced that The National Comprehensive Cancer Network Head and Neck Cancers Panel recommended the GnRH agonist goserelin for patients with recu
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Maintenance Mirvetuximab Soravtansine Plus Bevacizumab Under Exploration in FRα+ Ovarian Cancer

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September 1, 2023Courtney FlahertyThe efficacy of maintenance mirvetuximab soravtansine plus bevacizumab is being compared with bevacizumab alone in patients with folate receptor alpha–positive recurr
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Maintenance Mirvetuximab Soravtansine Plus Bevacizumab Under Exploration in FRα+ Ovarian Cancer

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