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Pelage Pharmaceuticals Advances Hair Loss Treatment with Phase 2 Study and $14M Funding

Pelage Pharmaceuticals Advances Hair Loss Treatment with Phase 2 Study and $14M Funding

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Dermatology August 14,2024
Pelage Pharmaceuticals Advances Hair Loss Treatment with Phase 2 Study and $14M Funding

Pelage Pharmaceuticals Advances Hair Loss Treatment with Phase 2 Study and $14M Funding

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Blood Types: What Letters, Positive, and Negative Signs Mean

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A histone post-translational modification linked to lifelong susceptibility to stress in mice

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A histone post-translational modification linked to lifelong susceptibility to stress in mice

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by Ingrid Fadelli , Medical XpressThe cover art theme is "the weight of a histone." This visual serves as a rodent metaphor for Atlas, a Titan from Greek mythology who was condemned to carry
Psychiatry & Mental Health October 09,2024
Largest-ever genetic study of epilepsy finds possible therapeutic targets

Largest-ever genetic study of epilepsy finds possible therapeutic targets

by Ari Navetta,Broad Institute of MIT and HarvardEpilepsy genetic architecture from large-scale genetic association studies. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024
Neurology October 09,2024
Largest-ever genetic study of epilepsy finds possible therapeutic targets

Largest-ever genetic study of epilepsy finds possible therapeutic targets

by Ari Navetta,Broad Institute of MIT and HarvardEpilepsy genetic architecture from large-scale genetic association studies. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024
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Unveiling genetic insights: How PAI-1 polymorphisms influence COVID-19 outcomes

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Unveiling genetic insights: How PAI-1 polymorphisms influence COVID-19 outcomes

Unveiling genetic insights: How PAI-1 polymorphisms influence COVID-19 outcomes

by Juntendo University Research Promotion CenterPAI-1 genetic variations impact blood clotting and inflammation in COVID-19, potentially guiding personalized treatments. Credit: Dr. Beate Heissig from
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Study reveals key role of TRIO gene in epileptic encephalopathies

Study reveals key role of TRIO gene in epileptic encephalopathies

byUniversity of MontrealDefective migration of MGE-derived cortical INs inTrio–/–embryos. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-024-02742-yWhat are the m
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Study reveals key role of TRIO gene in epileptic encephalopathies

Study reveals key role of TRIO gene in epileptic encephalopathies

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Genetic variants linked to Alzheimer's trigger brain inflammation in females, preclinical study finds

Genetic variants linked to Alzheimer's trigger brain inflammation in females, preclinical study finds

byWeill Cornell Medical CollegeInflammatory microglia from afemalebrainin amouse model ofAlzheimer's disease. The mice also carry the APOE4 and TREM2 genetic ri
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Genetic variants linked to Alzheimer's trigger brain inflammation in females, preclinical study finds

Genetic variants linked to Alzheimer's trigger brain inflammation in females, preclinical study finds

byWeill Cornell Medical CollegeInflammatory microglia from afemalebrainin amouse model ofAlzheimer's disease. The mice also carry the APOE4 and TREM2 genetic ri
Neurology October 09,2024
Comprehensive mapping of genetic activity brings hope to patients with chronic pain

Comprehensive mapping of genetic activity brings hope to patients with chronic pain

by Felicia Lindberg,Karolinska InstitutetTemporal molecular dynamics of nociceptors and pain states during neuropathic pain. Credit:Nature Communications(2024). DOI: 10.1038/s41467-0
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Comprehensive mapping of genetic activity brings hope to patients with chronic pain

Comprehensive mapping of genetic activity brings hope to patients with chronic pain

by Felicia Lindberg,Karolinska InstitutetTemporal molecular dynamics of nociceptors and pain states during neuropathic pain. Credit:Nature Communications(2024). DOI: 10.1038/s41467-0
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Live-cell model system can decode genetic risk for psychiatric disorders

Live-cell model system can decode genetic risk for psychiatric disorders

byUniversity of North Carolina at Chapel Hill School of MedicineGene regulatory changes induced by Wnt stimulation.a, Cartoon of the canonical Wnt signaling pathway.b, Schematic of s
Psychiatry & Mental Health October 09,2024
Live-cell model system can decode genetic risk for psychiatric disorders

Live-cell model system can decode genetic risk for psychiatric disorders

byUniversity of North Carolina at Chapel Hill School of MedicineGene regulatory changes induced by Wnt stimulation.a, Cartoon of the canonical Wnt signaling pathway.b, Schematic of s
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Research explores genetic treatment for rare arrhythmias

Research explores genetic treatment for rare arrhythmias

by Albert McKeon,Children's Hospital BostonCredit: CC0 Public DomainVariants in a gene that plays a key role in heart function can cause potentially life-threatening arrhythmia syndromes kno
Cardiovascular Diseases October 09,2024
Research explores genetic treatment for rare arrhythmias

Research explores genetic treatment for rare arrhythmias

by Albert McKeon,Children's Hospital BostonCredit: CC0 Public DomainVariants in a gene that plays a key role in heart function can cause potentially life-threatening arrhythmia syndromes kno
Cardiovascular Diseases October 09,2024
New genomic surveillance tools could help efforts to eliminate damaging parasitic infections

New genomic surveillance tools could help efforts to eliminate damaging parasitic infections

byWashington University in St. LouisOverview of experiments and analysis. (a) Brugia malayi experiments. Adult worms collected from an experimental host (gerbils) and microfilariae of a known pe
Public Health & Prevention October 09,2024
New genomic surveillance tools could help efforts to eliminate damaging parasitic infections

New genomic surveillance tools could help efforts to eliminate damaging parasitic infections

byWashington University in St. LouisOverview of experiments and analysis. (a) Brugia malayi experiments. Adult worms collected from an experimental host (gerbils) and microfilariae of a known pe
Public Health & Prevention October 09,2024
Scientists uncover genetic cause of rare autoimmune disorder

Scientists uncover genetic cause of rare autoimmune disorder

by Olivia Dimmer,Northwestern UniversityCredit: Unsplash/CC0 Public DomainA team of international scientists has uncovered the genetic underpinnings of a rare, inherited autoimmune disorder, acc
Reproduction October 09,2024
Scientists uncover genetic cause of rare autoimmune disorder

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by Olivia Dimmer,Northwestern UniversityCredit: Unsplash/CC0 Public DomainA team of international scientists has uncovered the genetic underpinnings of a rare, inherited autoimmune disorder, acc
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