Researchers identify the 'broken gate' causing unstoppable brain signals in severe childhood epilepsy

by Florey Institute of Neuroscience and Mental Health2D transmembrane topology of the wild-type (WT) Nav1.2 channel showing 27 domains DI−DIV and amino acid residues N1662 (cytosolic side of S5DIV) an

Neurology August 03,2024 0

Researchers identify the 'broken gate' causing unstoppable brain signals in severe childhood epilepsy

by Florey Institute of Neuroscience and Mental Health2D transmembrane topology of the wild-type (WT) Nav1.2 channel showing 27 domains DI−DIV and amino acid residues N1662 (cytosolic side of S5DIV) an

Neurology August 03,2024 0

Hydroxyurea does not reduce ovarian reserve in patients with sickle cell disease, study shows

byAmerican Society of HematologyCredit: National Institutes of HealthIn female patients living with sickle cell disease (SCD), hydroxyurea had no effect on ovarian reserve, suggesting that ferti

Obstetrics & Gynecology August 03,2024 0

Hydroxyurea does not reduce ovarian reserve in patients with sickle cell disease, study shows

byAmerican Society of HematologyCredit: National Institutes of HealthIn female patients living with sickle cell disease (SCD), hydroxyurea had no effect on ovarian reserve, suggesting that ferti

Obstetrics & Gynecology August 03,2024 0

Most studies of massage for pain show low certainty of evidence

by Lori SolomonMost reviews of the use of massage therapy for painful adult health conditions report low- or very low-certainty evidence, according to a reviewpublishedonline July 15 in&nb

Anesthesiology & Pain August 03,2024 0

Most studies of massage for pain show low certainty of evidence

by Lori SolomonMost reviews of the use of massage therapy for painful adult health conditions report low- or very low-certainty evidence, according to a reviewpublishedonline July 15 in&nb

Anesthesiology & Pain August 03,2024 0

Bird flu isn't spreading in humans for now—but there are vaccines in the pipeline if that changes

by Paul Griffin,The ConversationCredit: CC0 Public DomainSince May, a number of poultry farms around Australia have faced outbreaks ofavian influenza, or bird flu. These outbreaks have bee

Epidemiology & Public Health August 03,2024 0

Bird flu isn't spreading in humans for now—but there are vaccines in the pipeline if that changes

by Paul Griffin,The ConversationCredit: CC0 Public DomainSince May, a number of poultry farms around Australia have faced outbreaks ofavian influenza, or bird flu. These outbreaks have bee

Epidemiology & Public Health August 03,2024 0

Distinct signaling pathway identified as key driver for epithelial cancer development

by Kurt Bodenmüller,University of ZurichSide section of the skin with epidermal stem cells (green) with one particular clone in red. Cell nuclei are stained in blue, the white dashed lines indic

Oncology August 03,2024 0

Distinct signaling pathway identified as key driver for epithelial cancer development

by Kurt Bodenmüller,University of ZurichSide section of the skin with epidermal stem cells (green) with one particular clone in red. Cell nuclei are stained in blue, the white dashed lines indic

Oncology August 03,2024 0

Scientists develop first bone marrow model that supports human stem cells

byUniversity of GlasgowSchematic of the bone marrow (BM) niche microenvironment. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-50054-0Scientists have created the first

Oncology August 03,2024 0

Scientists develop first bone marrow model that supports human stem cells

byUniversity of GlasgowSchematic of the bone marrow (BM) niche microenvironment. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-50054-0Scientists have created the first

Oncology August 03,2024 0

Researchers discuss HER2-low and HER2-zero in breast cancer

by Impact Journals LLCMicrograph showing a lymph node invaded by ductal breast carcinoma, with extension of the tumor beyond the lymph node. Credit: Nephron/WikipediaA new editorial paper titled &quot

Oncology August 03,2024 0

Researchers discuss HER2-low and HER2-zero in breast cancer

by Impact Journals LLCMicrograph showing a lymph node invaded by ductal breast carcinoma, with extension of the tumor beyond the lymph node. Credit: Nephron/WikipediaA new editorial paper titled &quot

Oncology August 03,2024 0

Eliminating senescent cells could help treat breast, pancreatic cancers

byWashington University in St. LouisShown is a human breast tumor sample. The white arrows point to senescent cells in the tumor. Eliminating senescent cells, which drive inflammation, could bec

Oncology August 03,2024 0

Eliminating senescent cells could help treat breast, pancreatic cancers

byWashington University in St. LouisShown is a human breast tumor sample. The white arrows point to senescent cells in the tumor. Eliminating senescent cells, which drive inflammation, could bec

Oncology August 03,2024 0

Knockout of CD5 on CAR T cells shown to boost anti-tumor efficacy

byPerelman School of Medicine at the University of PennsylvaniaCD5 KO enhances CAR T cell cytotoxicity. Credit:Science Immunology(2024). DOI: 10.1126/sciimmunol.adn6509The effectiven

Oncology August 03,2024 0

Knockout of CD5 on CAR T cells shown to boost anti-tumor efficacy

byPerelman School of Medicine at the University of PennsylvaniaCD5 KO enhances CAR T cell cytotoxicity. Credit:Science Immunology(2024). DOI: 10.1126/sciimmunol.adn6509The effectiven

Oncology August 03,2024 0

Testosterone therapy may protect against breast cancer in trans masculine individuals

by Jacqueline Mitchell,Beth Israel Deaconess Medical Centera) Lobular atrophy was assessed by the pathologists using four categories. b) The duration of testosterone therapy (TT) significantly c

Oncology August 03,2024 0

Testosterone therapy may protect against breast cancer in trans masculine individuals

by Jacqueline Mitchell,Beth Israel Deaconess Medical Centera) Lobular atrophy was assessed by the pathologists using four categories. b) The duration of testosterone therapy (TT) significantly c

Oncology August 03,2024 0